Kimura Atsuko 木村敦子

… Alternative Names

KIMURA Atsuko 木村敦子

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Researcher Number	60569143
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所免疫研究部, 研究員 2025: 公益財団法人東京都医学総合研究所, 疾患制御研究分野, 研究員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所免疫研究部, 研究員 2022: 公益財団法人東京都医学総合研究所, 疾患制御研究分野, 研究員 2020 – 2021: 公益財団法人東京都医学総合研究所, 疾患制御研究分野, 主任研究員 2017 – 2019: 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 主任研究員 2013 – 2015: 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 主任研究員 2012: 公益財団法人東京都医学総合研究所, 運動・感覚システム研究分野, 研究員 2011: (財)東京都医学総合研究所, 運動・感覚システム研究分野, 研究員
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 52020:Neurology-related / Basic Section 56060:Ophthalmology-related / Neurochemistry/Neuropharmacology Except Principal Investigator Neurochemistry/Neuropharmacology
Keywords	Principal Investigator 緑内障 / 神経保護 / 神経変性疾患 / 視神経炎 / neuroinflammation / NKT cells / multiple sclerosis / 神経再生 / 軸索再生 / 遺伝子治療 … More / RGC / AAV / TrkB / HDAC阻害剤 / グルタミン酸 / 網膜神経節細胞 / グルタミン酸トランスポーター / グルタミン酸毒性 / バルプロ酸 / オリゴデンドロサイト / 脱髄 / 神経細胞死 / 神経変性 / Dock3 … More Except Principal Investigator GEF / アクチン骨格 / 軸索再生 / 多発性硬化症 / アルツハイマー病 / 微小管 / アクチン / 細胞死 / Dockファミリー / 視神経再生 / 神経変性疾患 / 神経保護 / 緑内障 / Dock3 Less

Research on pathogenic immune cells associated with the gut-brain axis in neuroinflammationPrincipal Investigator
- Principal Investigator
  
  木村敦子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  National Center of Neurology and Psychiatry
Gene therapy for glaucoma by stimulating neuroprotection and regenerationPrincipal Investigator
- Principal Investigator
  
  KIMURA Atsuko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Development of neuroprotective strategies for treatment of neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  KIMURA Atsuko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
The role of Dock molecules in glaucoma and optic neuritisPrincipal Investigator
- Principal Investigator
  
  KIMURA Atsuko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Dock family proteins in neurodegeneration
- Principal Investigator
  
  NAMEKATA Kazuhiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
New therapy for glaucoma and optic neuritis using Dock3Principal Investigator
- Principal Investigator
  
  KIMURA Atsuko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  公益財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] ASK1-p38 経路の阻害は視神経外傷後の神経細胞死を抑制する日本眼科学会雑誌2013
- Author(s)
  香留崇, 行方和彦, 郭暁麗, 仙波賢太郎, 橘高大二, 川村和人, 木村敦子, 原田知加子, 一條秀憲, 三田村佳典, 原田高幸
- Data Source
  KAKENHI-PROJECT-23300138
[Book] ASK1-p38 経路の阻害は視神経外傷後の神経細胞死を抑制する.2013
- Author(s)
  留　崇、行方和彦、郭　暁麗、仙波賢太郎、橘高大二、川村和人、木村敦子、原田知加子、一條秀憲、三田村佳典、原田高幸.
- Total Pages
  11
- Publisher
  日本眼科学会雑誌
- Data Source
  KAKENHI-PROJECT-23300138
[Book] Dock3 はグリコーゲン合成酵素キナーゼ-3β (GSK-3β)による微小管重合を介して軸索伸長を促進する日本眼科学会会誌2012
- Author(s)
  行方和彦, 原田知加子, 郭暁麗, 木村敦子, 橘高大二, 渡邉快記, 原田高幸
- Data Source
  KAKENHI-PROJECT-23300138
[Book] TLR-ASK1-p38経路による神経炎症と脱髄症状の制御日本眼科学会会誌2011
- Author(s)
  郭暁麗, 原田知加子, 行方和彦, 松沢厚, Monsterrat Camps, Hong Ji, Dominique Swinnen, Catherine Jorand-Lebrun, Mathilde Muzerelle, Pierre-Alain Vitte, Thomas Rückle, 木村敦子, 神山邦子, 松本陽, 一條秀憲, 原田高幸
- Data Source
  KAKENHI-PROJECT-23300138
[Book] Spermidine 投与による実験的自己免疫性脳脊髄炎の軽症化日本眼科学会会誌2011
- Author(s)
  郭暁麗, 原田知加子, 行方和彦, 木村敦子, 三田村佳典, 吉田寛, 松本陽, 原田高幸
- Data Source
  KAKENHI-PROJECT-23300138
[Book] 網膜の変性と再生過程におけるグリアおよび神経特異的なTrkB シグナルの機能解析日本眼科学会会誌2011
- Author(s)
  原田知加子, 郭暁麗, 行方和彦, 木村敦子, 中村和昭, 田中光一, Luis F. Parada, 原田高幸
- Data Source
  KAKENHI-PROJECT-23300138
[Journal Article] Effects of constitutively active K-Ras on axon regeneration after optic nerve injury2023
- Author(s)
  Kiyota Naoki、Namekata Kazuhiko、Nishijima Euido、Guo Xiaoli、Kimura Atsuko、Harada Chikako、Nakazawa Toru、Harada Takayuki
- Journal Title
  
  Neuroscience Letters
  
  Volume: 799 Pages: 137124-137124
- DOI
  10.1016/j.neulet.2023.137124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09804, KAKENHI-PROJECT-21K18279, KAKENHI-PROJECT-22K16985, KAKENHI-PROJECT-21K20979, KAKENHI-PROJECT-19KK0229, KAKENHI-PROJECT-21H02819, KAKENHI-PROJECT-20K07751, KAKENHI-PROJECT-20K09820, KAKENHI-PROJECT-21K09688
[Journal Article] Vision protection and robust axon regeneration in glaucoma models by membrane-associated Trk receptors.2023
- Author(s)
  Nishijima E, Honda S, Kitamura Y, Namekata K, Kimura A, Guo X, Azuchi Y, Harada C, Murakami A, Matsuda A, Nakano T, Parada LF, Harada T.
- Journal Title
  
  Mol Ther.
  
  Volume: 31 Issue: 3 Pages: 810-824
- DOI
  10.1016/j.ymthe.2022.11.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09819, KAKENHI-PROJECT-22K16961, KAKENHI-PROJECT-22K16985, KAKENHI-PROJECT-21K20979, KAKENHI-PROJECT-20K07751, KAKENHI-PROJECT-20K09820, KAKENHI-PROJECT-19KK0229, KAKENHI-PROJECT-22K09804, KAKENHI-PROJECT-23K06818, KAKENHI-PROJECT-21K09688, KAKENHI-PROJECT-21K18279, KAKENHI-PROJECT-21H02819
[Journal Article] Effects of lighting environment on the degeneration of retinal ganglion cells in glutamate/aspartate transporter deficient mice, a mouse model of normal tension glaucoma2022
- Author(s)
  Ohashi Tsutomu、Namekata Kazuhiko、Guo Xiaoli、Kimura Atsuko、Harada Chikako、Harada Takayuki
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 29 Pages: 101197-101197
- DOI
  10.1016/j.bbrep.2021.101197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-21H02819, KAKENHI-PROJECT-20K09820, KAKENHI-PROJECT-21K18279, KAKENHI-PROJECT-19KK0229, KAKENHI-PROJECT-21K09688, KAKENHI-PROJECT-22K09804, KAKENHI-PROJECT-20K07751
[Journal Article] ASK1 signaling regulates phase-specific glial interactions during neuroinflammation2022
- Author(s)
  Guo Xiaoli、Kimura Atsuko、Namekata Kazuhiko、Harada Chikako、Arai Nobutaka、Takeda Kohsuke、Ichijo Hidenori、Harada Takayuki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 6
- DOI
  10.1073/pnas.2103812119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-20K07032, KAKENHI-PROJECT-20K07751, KAKENHI-PROJECT-20K09820, KAKENHI-PROJECT-21K09688, KAKENHI-PROJECT-22K09804, KAKENHI-PROJECT-21K18279, KAKENHI-PROJECT-19KK0229, KAKENHI-PROJECT-21H04760, KAKENHI-PROJECT-21H02819
[Journal Article] リパスジル点眼は視神経損傷後の成体マウスにおいて神経保護と軸索再生を促進する2021
- Author(s)
  西島義道、行方和彦、木村敦子、郭　暁麗、原田知加子、野呂隆彦、中野　匡、原田高幸
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 125 Pages: 82-82
- Data Source
  KAKENHI-PROJECT-20K09820
[Journal Article] Topical ripasudil stimulates neuroprotection and axon regeneration in adult mice following optic nerve injury2020
- Author(s)
  Nishijima Euido、Namekata Kazuhiko、Kimura Atsuko、Guo Xiaoli、Harada Chikako、Noro Takahiko、Nakano Tadashi、Harada Takayuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15709-15709
- DOI
  10.1038/s41598-020-72748-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-20K07751, KAKENHI-PROJECT-20K09820, KAKENHI-PROJECT-19KK0229, KAKENHI-PROJECT-20K18365
[Journal Article] Roles of the DOCK-D family proteins in a mouse model of neuroinflammation2020
- Author(s)
  Namekata Kazuhiko、Guo Xiaoli、Kimura Atsuko、Azuchi Yuriko、Kitamura Yuta、Harada Chikako、Harada Takayuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: in press Issue: 19 Pages: 6710-6720
- DOI
  10.1074/jbc.ra119.010438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-18K19625, KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-20K07751, KAKENHI-PROJECT-20K09820, KAKENHI-PROJECT-20K18404
[Journal Article] Role of animal models in glaucoma research2020
- Author(s)
  Kimura Atsuko、Noro Takahiko、Harada Takayuki
- Journal Title
  
  Neural Regeneration Research
  
  Volume: 15 Issue: 7 Pages: 1257-1258
- DOI
  10.4103/1673-5374.272578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-17K11499, KAKENHI-PROJECT-18K19625, KAKENHI-PROJECT-20K18365
[Journal Article] Normal tension glaucoma-like degeneration of the visual system in aged marmosets2019
- Author(s)
  Noro Takahiko、Namekata Kazuhiko、Kimura Atsuko、Azuchi Yuriko、Hashimoto Nanako、Moriya-Ito Keiko、Komaki Yuji、Lee Chia-Ying、Okahara Norio、Guo Xiaoli、Harada Chikako、Kim Euido、Nakano Tadashi、Tsuneoka Hiroshi、Inoue Takashi、Sasaki Erika、Tokuno Hironobu、Harada Takayuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 14852-14852
- DOI
  10.1038/s41598-019-51281-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-16K10842, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-17K11499, KAKENHI-PROJECT-18K19625
[Journal Article] Survival of Alpha and Intrinsically Photosensitive Retinal Ganglion Cells in NMDA-Induced Neurotoxicity and a Mouse Model of Normal Tension Glaucoma2019
- Author(s)
  Honda Sari、Namekata Kazuhiko、Kimura Atsuko、Guo Xiaoli、Harada Chikako、Murakami Akira、Matsuda Akira、Harada Takayuki
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 60 Issue: 12 Pages: 3696-3707
- DOI
  10.1167/iovs.19-27145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-19K09980, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-18K19625
[Journal Article] DOCK8 is expressed in microglia, and it regulates microglial activity during neurodegeneration in murine disease models2019
- Author(s)
  Namekata Kazuhiko、Guo Xiaoli、Kimura Atsuko、Arai Nobutaka、Harada Chikako、Harada Takayuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 36 Pages: 13421-13433
- DOI
  10.1074/jbc.ra119.007645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-18K19625
[Journal Article] 2種類の正常眼圧緑内障モデルマウスの網膜変性にないするN-acetylcysteineの異なる効果2019
- Author(s)
  佐埜弘樹、行方和彦、木村敦子、設楽浩志、郭暁麗、原田知加子、三田村佳典、原田高幸
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 123 Pages: 619-619
- Data Source
  KAKENHI-PROJECT-17K07123
[Journal Article] Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma2019
- Author(s)
  Sano Hiroki、Namekata Kazuhiko、Kimura Atsuko、Shitara Hiroshi、Guo Xiaoli、Harada Chikako、Mitamura Yoshinori、Harada Takayuki
- Journal Title
  
  Cell Death & Disease
  
  Volume: 10 Issue: 2 Pages: 75-75
- DOI
  10.1038/s41419-019-1365-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-16K08635, KAKENHI-PROJECT-16K11288, KAKENHI-PROJECT-16K11308, KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-18K19625
[Journal Article] Topical Ripasudil Suppresses Retinal Ganglion Cell Death in a Mouse Model of Normal Tension Glaucoma2018
- Author(s)
  Akaiwa Kei、Namekata Kazuhiko、Azuchi Yuriko、Sano Hiroki、Guo Xiaoli、Kimura Atsuko、Harada Chikako、Mitamura Yoshinori、Harada Takayuki
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 59 Issue: 5 Pages: 2080-2089
- DOI
  10.1167/iovs.17-23276
- NAID
  120006956850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11308, KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-16K11288
[Journal Article] Role of neuritin in retinal ganglion cell death in adult mice following optic nerve injury.2018
- Author(s)
  Azuchi Y, Namekata K, Shimada T, Guo X, Kimura A, Harada C, Saito A, Yamagata K, Harada T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10132-10132
- DOI
  10.1038/s41598-018-28425-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07086, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-18H02536, KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-16K08635
[Journal Article] Recent advances in genetically modified animal models of glaucoma and their roles in drug repositioning2018
- Author(s)
  Harada Chikako、Kimura Atsuko、Guo Xiaoli、Namekata Kazuhiko、Harada Takayuki
- Journal Title
  
  British Journal of Ophthalmology
  
  Volume: 103 Issue: 2 Pages: 161-166
- DOI
  10.1136/bjophthalmol-2018-312724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-16K08635, KAKENHI-PROJECT-16K11308, KAKENHI-PROJECT-19K09943, KAKENHI-PROJECT-18K19625
[Journal Article] The renin-angiotensin system regulates neurodegeneration in a mouse model of optic neuritis2017
- Author(s)
  Guo X., Namekata K., Kimura A., Harada C. & Harada T
- Journal Title
  
  American journal of pathology
  
  Volume: 187 Issue: 12 Pages: 2876-2885
- DOI
  10.1016/j.ajpath.2017.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-16K08635, KAKENHI-PROJECT-16K11308, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-15H04999
[Journal Article] Targeting oxidative stress for treatment of glaucoma and optic neuritis.2017
- Author(s)
  Kimura, A., Namekata, K., Guo, X., Noro, T., Harada, C., Harada, T.
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2017 Issue: 1 Pages: 2817252-2817252
- DOI
  10.1155/2017/2817252
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-16K08635, KAKENHI-PROJECT-16K11308, KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-17K11499
[Journal Article] Edaravone prevents retinal degeneration in adult mice following optic nerve injury.2017
- Author(s)
  Akiyama G, Azuchi Y, Guo X, Noro T, Kimura A, Harada C, *Namekata K, Harada T
- Journal Title
  
  Investigative Ophthalmology & Visual Science
  
  Volume: 58 Issue: 11 Pages: 4908-4914
- DOI
  10.1167/iovs.17-22250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08635, KAKENHI-PROJECT-16K11308, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-17K11499, KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-16K20341
[Journal Article] Valproic acid and ASK1 deficiency ameliorate optic neuritis and neurodegeneration in an animal model of multiple sclerosis.2017
- Author(s)
  Azuchi, Y., Kimura, A., Guo, X., Akiyama, G., Noro, T., Harada, C., Nishigaki, A., Namekata, K., Harada, T.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 639 Pages: 82-87
- DOI
  10.1016/j.neulet.2016.12.057
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-16K08635, KAKENHI-PROJECT-16K11308, KAKENHI-PROJECT-16K20341, KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-17K07123
[Journal Article] Valproic acid prevents retinal degeneration in a murine model of normal tension glaucoma2015
- Author(s)
  Kimura, A., Guo, X., Noro, T., Harada, C., Tanaka, K., Namekata, K. and Harada, T
- Journal Title
  
  Neuroscience Letters
  
  Volume: 588 Pages: 108-113
- DOI
  10.1016/j.neulet.2014.12.054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Valproic acid prevents NMDA-induced retinal ganglion cell death via stimulation of neuronal TrkB receptor signaling2015
- Author(s)
  Kimura, A., Namekata, K., Guo, X., Noro, T., Harada, C. and Harada, T.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 185 Issue: 3 Pages: 756-764
- DOI
  10.1016/j.ajpath.2014.11.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Spermidine ameliorates neurodegeneration in a mouse model of normal tension glaucoma.2015
- Author(s)
  Noro, T., Namekata, K., Azuchi, Y., Kimura, A., Guo, X., Harada, C., Nakano, T., Tsuneoka, H., Harada, T.
- Journal Title
  
  Investigative Ophthalmology & Visual Science
  
  Volume: 56 Issue: 8 Pages: 5012-5019
- DOI
  10.1167/iovs.15-17142
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Brimonidine suppresses loss of retinal neurons and visual function in a murine model of optic neuritis2015
- Author(s)
  Guo, X., Namekata, K., Kimura, A., Noro, T., Azuchi, Y., Semba, K., Harada, C., Yoshida, H., Mitamura, Y. and Harada, T.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 592 Pages: 27-31
- DOI
  10.1016/j.neulet.2015.02.059
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-15K20266, KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Spermidine promotes retinal ganglion cell survival and optic nerve regeneration in adult mice following optic nerve injury.2015
- Author(s)
  Noro, T., Namekata, K., Kimura, A., Guo, X., Azuchi, Y., Harada, C., Nakano, T., Tsuneoka, H. and Harada, T.
- Journal Title
  
  Cell Death and Disease
  
  Volume: 6 Issue: 4 Pages: e1720-e1720
- DOI
  10.1038/cddis.2015.93
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] TrkB signaling in retinal glia stimulates neuroprotection after optic nerve injury.2015
- Author(s)
  Harada, C., Azuchi, Y., Noro, T., Guo, X., Kimura, A., Namekata, K., Harada, T.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 185 Issue: 12 Pages: 3238-3247
- DOI
  10.1016/j.ajpath.2015.08.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04999, KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Dock3 protects myelin in the cuprizone model for demyelination.2014
- Author(s)
  Namekata K, Kimura A, Harada C, Yoshida H, Matsumoto Y, Harada T.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 5 Issue: 8 Pages: e1395-e1395
- DOI
  10.1038/cddis.2014.357
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Dock GEFs and their therapeutic potential: neuroprotection and axon regeneration.2014
- Author(s)
  Namekata K, Kimura A, Kawamura K, Harada C, Harada T.
- Journal Title
  
  Prog Retin Eye Res.
  
  Volume: 43 Pages: 1-16
- DOI
  10.1016/j.preteyeres.2014.06.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Dock3 overexpression and p38 MAPK inhibition synergistically stimulate neuroprotection and axon regeneration after optic nerve injury.2014
- Author(s)
  Semba K, Namekata K, Kimura A, Harada C, Katome T, Yoshida H, Mitamura Y, Harada, T
- Journal Title
  
  Neurosci Lett
  
  Volume: 581 Pages: 89-93
- DOI
  10.1016/j.neulet.2014.08.034
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462717, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043, KAKENHI-PROJECT-26640048, KAKENHI-PROJECT-26861479
[Journal Article] Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma.2013
- Author(s)
  Namekata K, Kimura A, Kawamura K, Guo X, Harada C, Tanaka K, Harada, T.
- Journal Title
  
  Cell Death and Differentiation
  
  Volume: 20 Issue: 9 Pages: 1250-1256
- DOI
  10.1038/cdd.2013.91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138, KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043
[Journal Article] Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma2013
- Author(s)
  Namekata K, Kimura A, Kawamura K, Guo X, Harada C, Tanaka K, Harada, T
- Journal Title
  
  Cell Death and Differentiation
  
  Volume: 20 Pages: 1250-1256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138
[Journal Article] ASK1-p38 経路の阻害は視神経外傷後の神経細胞死を抑制する2013
- Author(s)
  香留崇、行方和彦、郭暁麗、仙波賢太郎、橘高大二、川村和人、木村敦子、原田知加子、一條秀憲、三田村佳典、原田高幸
- Journal Title
  
  日眼会誌
  
  Volume: 117(2) Pages: 161-161
- Data Source
  KAKENHI-PROJECT-23792024
[Journal Article] Inhibition of ASK1-p38 pathway prevents neural cell death following optic nerve injury2013
- Author(s)
  Katome, T., Namekata, K., Guo, X., Semba, K., Kittaka, D., Kawamura, K., Kimura, A., Harada, C., Ichijo, H., Mitamura, Y. and Harada, T
- Journal Title
  
  Cell Death and Differentiation
  
  Volume: 20 Pages: 270-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138
[Journal Article] Inhibition of ASK1-p38 pathway prevents neural cell death following optic nerve injury.2013
- Author(s)
  Katome, T., Namekata, K., Guo, X., Semba, K., Kittaka, D., Kawamura, K., Kimura, A., Harada, C., Ichijo, H., Mitamura, Y. and Harada, T.
- Journal Title
  
  Cell Death Differ.
  
  Volume: 20 Issue: 2 Pages: 270-280
- DOI
  10.1038/cdd.2012.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229004, KAKENHI-PROJECT-22591929, KAKENHI-PROJECT-23300138, KAKENHI-PROJECT-23659033, KAKENHI-PROJECT-23700459, KAKENHI-PROJECT-23792024, KAKENHI-PROJECT-23890254, KAKENHI-PROJECT-24791884, KAKENHI-PROJECT-25430082, KAKENHI-PROJECT-25462766, KAKENHI-PROJECT-25640043
[Journal Article] Dock3 regulates BDNF-TrkB signaling for neurite outgrowth by forming a ternary complex with Elmo and RhoG2012
- Author(s)
  Namekata K, Watanabe H, Guo X, Kittaka D, Kawamura K, Kimura A, Harada C, Harada T
- Journal Title
  
  Genes Cells
  
  Volume: 17(8) Pages: 688-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138
[Journal Article] Dock3はグリコーゲン合成酵素キナーゼ-3β (GSK-3β)による微小管重合を介して軸索伸長を促進する2012
- Author(s)
  行方和彦、原田知加子、郭暁麗、木村敦子、橘高大二、渡邉快記、原田高幸
- Journal Title
  
  日眼会誌
  
  Volume: 116(5) Pages: 527-527
- Data Source
  KAKENHI-PROJECT-23792024
[Journal Article] Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly2012
- Author(s)
  Namekata K., Harada C., Guo X., Kimura H., Kittaka D., Watanabe H., Harada T.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 32 Issue: 1 Pages: 264-274
- DOI
  10.1523/jneurosci.4884-11.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138, KAKENHI-PROJECT-23792024, KAKENHI-PROJECT-23890254, KAKENHI-PROJECT-24700392
[Journal Article] Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly2012
- Author(s)
  Namekata K, Harada C, Guo X, Kimura A, Kittaka D, Watanabe H, and Harada T
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 32 (1) Pages: 264-274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138
[Journal Article] Dock3 regulates BDNF-TrkB signaling for neurite outgrowth by forming a ternary complex with Elmo and RhoG.2012
- Author(s)
  Namekata K、他6名
- Journal Title
  
  Genes to Cells.
  
  Volume: 17 Issue: 8 Pages: 688-697
- DOI
  10.1111/j.1365-2443.2012.01616.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138, KAKENHI-PROJECT-23792024, KAKENHI-PROJECT-23890254, KAKENHI-PROJECT-24700392, KAKENHI-PROJECT-24791884
[Journal Article] Spermidine alleviates severity of murine experimental autoimmune encephalomyelitis2011
- Author(s)
  Guo, X., Harada, C., Namekata, K., Kimura, A., Mitamura, Y., Yoshida, H., Matsumoto, Y., and Harada, T
- Journal Title
  
  Investigative Ophthalmology & Visual Science
  
  Volume: 52(5) Issue: 5 Pages: 2696-2703
- DOI
  10.1167/iovs.10-6015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792024, KAKENHI-PROJECT-23890254
[Journal Article] Spermidine alleviates severity of murine experimental autoimmune encephalomyelitis2011
- Author(s)
  Guo X, Harada C, Namekata K, Kimura A., Mitamura Y., Yoshida H., Matsumuto Y., Harada T
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 52(5) Pages: 2696-2703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138
[Journal Article] Spermidine投与による実験的自己免疫性脳脊髄炎の軽症化2011
- Author(s)
  郭暁麗、原田知加子、行方和彦、木村敦子、三田村佳典、吉田寛、松本陽、原田高幸
- Journal Title
  
  日眼会誌
  
  Volume: 115(8) Pages: 729-729
- Data Source
  KAKENHI-PROJECT-23792024
[Journal Article] Glia- and neuron-specific functions of TrkB signaling during retinal degeneration and regeneration2011
- Author(s)
  Harada, C.
- Journal Title
  
  Nature Communications
  
  Volume: 2 Issue: 1 Pages: 1-9
- DOI
  10.1038/ncomms1190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300137, KAKENHI-PROJECT-23700459, KAKENHI-PROJECT-23792024, KAKENHI-PROJECT-23890254
[Journal Article] 網膜の変性と再生過程におけるグリアおよび神経特異的なTrkBシグナルの機能解析2011
- Author(s)
  原田知加子、郭暁麗、行方和彦、木村敦子、中村和昭、田中光一、Luis F. Parada、原田高幸
- Journal Title
  
  日眼会誌
  
  Volume: 115(7) Pages: 637-637
- Data Source
  KAKENHI-PROJECT-23792024
[Journal Article] TLR-ASK1-p38経路による神経炎症と脱髄症状の制御2011
- Author(s)
  郭暁麗、原田知加子、行方和彦、松沢厚、Monsterrat Camps、Hong Ji、Dominique Swinnen、Catherine Jorand-Lebrun、Mathilde Muzerelle、Pierre-Alain Vitte、Thomas Ruckle、木村敦子、神山邦子、松本陽、一條秀憲、原田高幸
- Journal Title
  
  日眼会誌
  
  Volume: 115(5) Pages: 485-485
- Data Source
  KAKENHI-PROJECT-23792024
[Journal Article] Glia- and neuron-specific functions of TrkB signaling during retinal degeneration and regeneration2011
- Author(s)
  Harada C, Guo X, Namekata K, Kimura A, Nakamura K, Tanaka K, Parada LF, Harada T
- Journal Title
  
  Nature Communications
  
  Volume: 2 Pages: 189-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300138
[Journal Article] Dock3 attenuates neural cell death due to NMDA neurotoxicity and oxidative stress in a mouse model of normal tension glaucoma
- Author(s)
  Namekata, K., Kimura, A., Kawamura, K., Guo, X., Harada, C., Tanaka, K. and Harada, T
- Journal Title
  
  Cell Death and Differentiation
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792024
[Presentation] AAV-mediated delivery of constitutively active TrkB promotes CNS axon regeneration and neuroprotection2021
- Author(s)
  Atsuko Kimura, Euido Nishijima, Yuta Kitamura, Sari Honda, Xiaoli Guo, Chikako Harada, Kazuhiko Namekata, Takayuki Harada
- Organizer
  Neuroscience 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] Gene therapy with modified TrkB induces neuroprotection and axon regeneration2021
- Author(s)
  Atsuko Kimura, Euido Nishijima, Yuta Kitamura, Sari Honda, Xiaoli Guo, Chikako Harada, Kazuhiko Namekata, Takayuki Harada
- Organizer
  第44回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] Microglial DOCK8 and neurodegeneration2021
- Author(s)
  Atsuko Kimura, Kazuhiko Namekata, Xiaoli Guo, Nobutaka Arai, Chikako Harada, Takayuki Harada
- Organizer
  The 4th International Conference on Applied Biochemistry and Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] 活性型TrkBを用いた遺伝子治療は上丘における網膜神経節細胞の軸索再生を促進する2020
- Author(s)
  本田紗里、金義道、北村裕太、郭暁麗、木村敦子、行方和彦、松田彰、村上晶、原田高幸
- Organizer
  第１２４回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] TrkB欠損マウスにおける網膜神経節細胞の変性過程の検討2020
- Author(s)
  北村裕太、安土ゆり子、行方和彦、木村敦子、郭暁麗、山本修一、原田高幸
- Organizer
  第７４回日本臨床眼科学会
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] 活性型Rasの遺伝子治療による視神経保護と再生への影響2020
- Author(s)
  金義道、本田紗里、北村裕太、郭暁麗、木村敦子、行方和彦、中野匡、原田高幸
- Organizer
  第１２４回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] TrkB欠損マウスにおける網膜神経節細胞の変性過程の検討2020
- Author(s)
  北村裕太、安土ゆり子、行方和彦、木村敦子、郭暁麗、山本修一、原田高幸
- Organizer
  第１２４回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] GLAST欠損マウスによる網膜神経節細胞樹状突起の解析2020
- Author(s)
  北村裕太、行方和彦、木村敦子、郭暁麗、山本修一、原田高幸
- Organizer
  第３１回日本緑内障学会
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] 失明からの視機能回復に向けた新規遺伝子治療ベクターの開発2020
- Author(s)
  金義道、行方和彦、本田紗里、木村敦子、北村裕太、中野匡、原田高幸
- Organizer
  第１９回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K09820
[Presentation] ２種類の緑内障モデルマウスにおけるN-acetylcysteineの異なる神経保護効果2019
- Author(s)
  佐埜弘樹、行方和彦、木村敦子、郭　暁麗、原田知加子、三田村佳典、原田高幸
- Organizer
  第１２３回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] 緑内障モデルマウスにおけるaRGCおよびipRGCの障害耐性2019
- Author(s)
  本田沙里、行方和彦、木村敦子、郭　暁麗、松田彰、村上晶、原田高幸
- Organizer
  第１２３回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] 活性型TrkBを用いた遺伝子治療による神経保護と視神経軸索の再生効果2019
- Author(s)
  金　義道、本田沙里、安土ゆり子、郭　暁麗、木村敦子、行方和彦、中野匡、原田高幸
- Organizer
  第１２３回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] Spontaneous normal tension glaucoma in aged marmosets2019
- Author(s)
  Takayuki Harada, Takahiko Noro, Kazuhiko Namekata, Atsuko Kimura, Nanako Hashimoto, Keiko Moriya-Ito, Xiaoli Guo, Chikako Harada, Tadashi Nakano, Takashi Inoue, Erika Sasaki
- Organizer
  8th World Glaucoma Cogress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] 正常眼圧緑内障モデルマウスを用いたEdaravoneによる網膜神経節細胞保護効果の検討2018
- Author(s)
  赤岩慶、行方和彦、安土ゆり子、郭　暁麗、木村敦子、原田知加子、三田村佳典、原田高幸
- Organizer
  第１２２回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] Loss of neuritin accelerates RGC loss and retinal degeneration in adult mice following optic nerve injury2018
- Author(s)
  Yuriko Azuchi, Kazuhiko Namekata, Tadayuki Shimada, Xiaoli Guo, Atsuko Kimura, Chikako Harada, Atsuko Nishigaki, Kanato Yamagata, Takayuki Harada
- Organizer
  48th Annual Meeting of the Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] Topical ripasudil prevents retinal ganglion cell death in a mouse model of normal tension glaucoma2018
- Author(s)
  Takayuki Harada, Kei Akaiwa, Kazuhiko Namekata, Yuriko Azuchi, Xiaoli Guo, Atsuko Kimura, Chikako Harada, Yoshinori Mitamura
- Organizer
  13th European Glaucoma Society Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] Can valproic acid treat neurodegenerative diseases?2018
- Author(s)
  Atsuko Kimura, Kazuhiko Namekata, Xiaoli Guo, Yuriko Azuchi, Chikako Harada, Takayuki Harada
- Organizer
  International Conference on Neurovascular and Neurodegenerative Diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] DOCK8 regulates microglial activity in neuroinflammation2018
- Author(s)
  Kazuhiko Namekata, Xiaoli Guo, Atsuko Kimura, Nobutaka Arai, Chikako Harada, Takayuki Harada
- Organizer
  19th International Congress of Neuropathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] Manipulation of retinal glutamate levels by overexpression of GLAST reduces retinal ganglion cell death in an experimental model of glaucoma2018
- Author(s)
  Atsuko Kimura, Kazuhiko Namekata, Xiaoli Guo, Yuriko Azuchi, Chikako Harada, Takayuki Harada
- Organizer
  19th International Congress of Neuropathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] カロリー制限による正常眼圧緑内障モデルにおける網膜神経節細胞及び視機能の保護2017
- Author(s)
  郭暁麗、木村敦子、安土ゆり子、秋山悟一、野呂隆彦、原田知加子、行方和彦、原田高幸
- Organizer
  第１２１回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] Role of glial and neuronal TrkB signaling in protection of retinal ganglion cells following optic nerve injury2017
- Author(s)
  Yuriko Azuchi, Atsuko Kimura, Chikako Harada, Kazuhiko Namekata, Takayuki Harada
- Organizer
  47 th Annual Meeting of the Society for Neuroscience（国際学会）
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] 細胞種特異的なASK1遺伝子の欠損が神経炎症に与える影響の検討2017
- Author(s)
  郭暁麗、行方和彦、木村敦子、原田知加子、新井信隆、原田高幸
- Organizer
  第５８回日本神経病理学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] 神経炎症におけるDock8の機能解析2017
- Author(s)
  行方和彦、郭　暁麗、木村敦子、原田知加子、新井信隆、原田高幸
- Organizer
  第５８回日本神経病理学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] コモン・マーモセットを用いた緑内障研究2017
- Author(s)
  野呂隆彦、行方和彦、木村敦子、中野匡、常岡寛、原田高幸
- Organizer
  第１２１回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K07123
[Presentation] ブリモニジンは正常眼圧緑内障モデルマウスにおける神経変性を抑制する.2015
- Author(s)
  仙波賢太郎、行方和彦、木村敦子、原田知加子、三田村佳典、原田高幸.
- Organizer
  第119回　日本眼科学会総会
- Place of Presentation
  札幌芸文館（北海道札幌市）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-26861479
[Presentation] Brimonidine suppresses loss of retinal neurons and visual function in murine models of glaucoma and optic neuritis.2015
- Author(s)
  Xiaoli Guo, Kazuhiko Namekata, Atsuko Kimura, Takahiko Noro, Chikako Harada, Takayuki Harada.
- Organizer
  45th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861479
[Presentation] Valproic acid protects retinal neurons from NMDA-induced neurotoxicity via stimulation of neuronal TrkB receptors.2015
- Author(s)
  Atsuko Kimura, Kazuhiko Namekata, Xiaoli Guo, Takahiko Noro, Chikako Harada, Takayuki Harada.
- Organizer
  2015 Asia-ARVO
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-02-18
- Data Source
  KAKENHI-PROJECT-26861479
[Presentation] Spermidine stimulates neuroprotection and optic nerve regeneration following optic nerve injury.2015
- Author(s)
  Takahiko Noro , Kazuhiko Namekata, Xiaoli Guo, Atsuko Kimura, Yuriko Azuchi, Tadashi Nakano, Hiroshi Tsuneoka, Takayuki Harada.
- Organizer
  2015 Asia-ARVO
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-02-18
- Data Source
  KAKENHI-PROJECT-26861479
[Presentation] Dock3はERKシグナルを介して視神経の脱髄を抑制する.2015
- Author(s)
  行方和彦、木村敦子、郭　曉麗、原田知加子、原田高幸.
- Organizer
  第119回　日本眼科学会総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26861479
[Presentation] Brimonidine protects retinal neurons and visual function in a murine model of optic neuritis.2015
- Author(s)
  Guo X., Namekata K., Kimura A., Noro T., Harada C. & Harada T.
- Organizer
  第119回　日本眼科学会総会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-26861479
[Presentation] Neuroprotection by valproic acid and spermidine in a mouse model of normal tension glaucoma.2015
- Author(s)
  Takayuki Harada, Atsuko Kimura, Takahiko Noro, Xiaoli Guo, Kazuhiko Namekata, Chikako Harada
- Organizer
  45th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861479
[Presentation] ASK1 inhibition ameliorates optic neuritis by modulating glial innate immunity. Oral session : Macrophages and micro glial regulation of ocular inflammation2012
- Author(s)
  Guo X, Harada C, Namekata K, Kimura A, Harada T
- Organizer
  XX International Congress of Eye Research (ISER2012)
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-07-23
- Data Source
  KAKENHI-PROJECT-23300138
[Presentation] The role of Dock3 in axon regeneration following optic nerve injury2012
- Author(s)
  Kazuhiko Namekata, Chikako Harada, Xiaoli Guo, Atsuko Kimura, Takayuki Harada
- Organizer
  XX International Congress of Eye Research (ISER 2012)
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-07-24
- Data Source
  KAKENHI-PROJECT-23792024
[Presentation] Session "Macrophages and microglial regulation of ocular inflammation" ASK1 inhibition ameliorates optic neuritis by modulating glial innate immunity2012
- Author(s)
  Xiaoli Guo, Chikako Harada, Kazuhiko Namekata, Atsuko Kimura, Takayuki Harada
- Organizer
  XX International Congress of Eye Research (ISER2012)
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-07-23
- Data Source
  KAKENHI-PROJECT-23792024
[Presentation] The role of Dock3 in axon regeneration following optic nerve injury2012
- Author(s)
  Namekata K, Harada C, Guo X, Kimura A, Harada T
- Organizer
  Poster session : Retinal cell biology, XX International Congress of Eye Research (ISER 2012)
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-07-24
- Data Source
  KAKENHI-PROJECT-23300138
[Presentation] ASK1 inhibition ameliorates optic neuritis by modulating glial innate immunity2011
- Author(s)
  Guo X., Harada C., Namekata K., Kimura A., Ichijo H. & Harada T
- Organizer
  26th Asia Pacific Academy of Ophthalmology (APAO) Congress
- Place of Presentation
  Sydney
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-23300138
[Presentation] ASK1 inhibition ameliorates optic neuritis by modulating glial innate immunity2011
- Author(s)
  Xiaoli Guo, Chikako Harada, Kazuaki Nakamura, Atsuko Kimura, Hidenori Ichijo, Takayuki Harada
- Organizer
  The 26th Asia Pacific Academy of Ophthalmology (APAO) Congress
- Place of Presentation
  Sydney, Australia
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-23792024

1. NAMEKATA Kazuhiko (70392355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
2. GUO Xiaoli (50443114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
3. WATANABE Hayaki (70595587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. HARADA takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
5. 原田知加子

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
6. 島田忠之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 一條秀憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 三田村佳典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 松田彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Atsuko 木村 敦子

KIMURA Atsuko 木村 敦子

Research Projects

Research Products

Co-Researchers

Research on pathogenic immune cells associated with the gut-brain axis in neuroinflammationPrincipal Investigator

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Gene therapy for glaucoma by stimulating neuroprotection and regenerationPrincipal Investigator

Principal Investigator

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Development of neuroprotective strategies for treatment of neurodegenerative diseasesPrincipal Investigator

Principal Investigator

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The role of Dock molecules in glaucoma and optic neuritisPrincipal Investigator

Principal Investigator

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Dock family proteins in neurodegeneration

Principal Investigator

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Research Institution

New therapy for glaucoma and optic neuritis using Dock3Principal Investigator

Principal Investigator

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Research Institution

[Book] ASK1-p38 経路の阻害は視神経外傷後の神経細胞死を抑制する 日本眼科学会雑誌2013

Author(s)

Data Source

[Book] ASK1-p38 経路の阻害は視神経外傷後の神経細胞死を抑制する.2013

Author(s)

Total Pages

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Data Source

[Book] Dock3 はグリコーゲン合成酵素キナーゼ-3β (GSK-3β)による微小管重合を介して軸索伸長を促進する 日本眼科学会会誌2012

Author(s)

Data Source

[Book] TLR-ASK1-p38経路による神経炎症と脱髄症状の制御 日本眼科学会会誌2011

Author(s)

Data Source

[Book] Spermidine 投与による実験的自己免疫性脳脊髄炎の軽症化 日本眼科学会会誌2011

Author(s)

Data Source

[Book] 網膜の変性と再生過程におけるグリアおよび神経特異的なTrkB シグナルの機能解析 日本眼科学会会誌2011

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Data Source

[Journal Article] Effects of constitutively active K-Ras on axon regeneration after optic nerve injury2023

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[Journal Article] Vision protection and robust axon regeneration in glaucoma models by membrane-associated Trk receptors.2023

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[Journal Article] Effects of lighting environment on the degeneration of retinal ganglion cells in glutamate/aspartate transporter deficient mice, a mouse model of normal tension glaucoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ASK1 signaling regulates phase-specific glial interactions during neuroinflammation2022

Author(s)

Journal Title

DOI

Kimura Atsuko 木村敦子

KIMURA Atsuko 木村敦子

[Book] ASK1-p38 経路の阻害は視神経外傷後の神経細胞死を抑制する日本眼科学会雑誌2013

[Book] Dock3 はグリコーゲン合成酵素キナーゼ-3β (GSK-3β)による微小管重合を介して軸索伸長を促進する日本眼科学会会誌2012

[Book] TLR-ASK1-p38経路による神経炎症と脱髄症状の制御日本眼科学会会誌2011

[Book] Spermidine 投与による実験的自己免疫性脳脊髄炎の軽症化日本眼科学会会誌2011

[Book] 網膜の変性と再生過程におけるグリアおよび神経特異的なTrkB シグナルの機能解析日本眼科学会会誌2011