Mogushi Kaoru 茂櫛薫

… Alternative Names

Researcher Number	60569292
Other IDs
Affiliation (Current)	2020: 順天堂大学, 医学(系)研究科(研究院), 非常勤講師 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師
Affiliation (based on the past Project Information) *help	2018 – 2019: 順天堂大学, 医学(系)研究科(研究院), 非常勤講師 2017: 順天堂大学, 医学(系)研究科(研究院), 講師 2014 – 2016: 順天堂大学, 医学(系)研究科(研究院), 助教 2015: 順天堂大学大学院医学系研究科ゲノム, 再生医療センター, 助教 2014: 順天堂大学, 医学(系)研究科, 助教 2013: 東京医科歯科大学, 難治疾患研究所, 非常勤講師
Review Section/Research Field	Principal Investigator Digestive surgery / Tumor therapeutics / Basic Section 43060:System genome science-related Except Principal Investigator Digestive surgery / Respiratory organ internal medicine / Gastroenterology / Medical genome science / General surgery / Surgical dentistry / Basic Section 53030:Respiratory medicine-related / Basic Section 55040:Respiratory surgery-related
Keywords	Principal Investigator 遺伝子発現解析 / バイオインフォマティクス / 肝細胞癌 / 部分最小二乗回帰 / 多変量解析 / シグナル伝達 / マイクロアレイ / 仮想ダイセクション法 / 教師なし学習 / 仮想ダイセクション / 臨床検体 / 遺伝子発現情報 … More Except Principal Investigator … More

Development and its application of the "virtual dissection" method using gene expression profiles of clinical specimensPrincipal InvestigatorOngoing
- Principal Investigator
  
  茂櫛薫
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Juntendo University
胸腺癌における新規治療標的遺伝子異常の探索Ongoing
- Principal Investigator
  
  高橋和久
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Juntendo University
CAGE発現解析を用いた大腸がん肺転移予測マーカーの特定Ongoing
- Principal Investigator
  
  柳沼行宏
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Juntendo University
小細胞肺癌における新規治療標的遺伝子異常の解析Ongoing
- Principal Investigator
  
  高橋史行
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Identification of biomaker for predicting liver metastasis of colorectal cancer with CAGE analysisOngoing
- Principal Investigator
  
  小見山博光
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Juntendo University
Inactivation of tumor suppressor by histone methylation in lung cancer
- Principal Investigator
  
  Tajima Ken
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Development of biomarker for detection of lymphnode metastasis and prediction of recurrence in colorectal cancer using CAGE analysis
- Principal Investigator
  
  Okuzawa Atsushi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Juntendo University
Searching for miRNA as a biomarker in blood colorectal cancer in blood to evaluate sensitivities against chemotherapies for colorectal cancer
- Principal Investigator
  
  TAKAHSHI Makoto
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Juntendo University
Construction of personalized monitoring system for colorectal caner using circulating tumor DNA
- Principal Investigator
  
  KAMIYAMA HIROHIKO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Juntendo University
Study on formation and evaluation method of intratumoral heterogeneity in oral cancer
- Principal Investigator
  
  UZAWA NARIKAZU
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Osaka University
  Tokyo Medical and Dental University
System-based drug discovery database using partial least square regressionPrincipal Investigator
- Principal Investigator
  
  MOGUSHI Kaoru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
  Tumor therapeutics
- Research Institution
  Juntendo University
Identification and clinical application of pathway-based markers for cancer
- Principal Investigator
  
  Tanaka Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical genome science
- Research Institution
  Tokyo Medical and Dental University
Functional analysis of oxidative stress-induced hepatocarcinogenic genes for molecular target treatment
- Principal Investigator
  
  TSUBOTA Akihito
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Jikei University School of Medicine

All 2019 2018 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Comprehensive molecular and immunological characterization of hepatocellular carcinoma2019
- Author(s)
  Shimada S, Mogushi K, Akiyama Y, Furuyama T, Watanabe S, Ogura T, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Tanabe M, Wands JR, Tanaka S.
- Journal Title
  
  EBioMedicine.
  
  Volume: 40 Pages: 457-470
- DOI
  10.1016/j.ebiom.2018.12.058
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670
[Journal Article] Identification of genes and pathways, including the CXCL2 axis, altered by DNA methylation in hepatocellular carcinoma.2019
- Author(s)
  Subat S, Mogushi K, Yasen M, Kohda T, Ishikawa Y, Tanaka H.
- Journal Title
  
  Journal of cancer research and clinical oncology
  
  Volume: 145(3) Pages: 675-684
- DOI
  10.1007/s00432-018-2824-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08798
[Journal Article] Glucose metabolism changes during the development and progression of oral tongue squamous cell carcinomas2019
- Author(s)
  Nakazato K, Mogushi K, Kayamori K, Tsuchiya M, Takahashi KI, Sumino J, Michi Y, Yoda T, Uzawa N.
- Journal Title
  
  Oncology Letters
  
  Volume: 18 Pages: 1372-1380
- DOI
  10.3892/ol.2019.10420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06198
[Journal Article] Idebenone has preventative and therapeutic effects on pulmonary fibrosis via preferential suppression of fibroblast activity2019
- Author(s)
  Sugizaki T, Tanaka KI, Asano T, Kobayashi D, Hino Y, Takafuji A, Shimoda M, Mogushi K, Kawahara M, Mizushima T.
- Journal Title
  
  Cell Death Discovery
  
  Volume: 5 Pages: 146-146
- DOI
  10.1038/s41420-019-0226-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06198
[Journal Article] Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism2019
- Author(s)
  Nakayama S, Shimonaka S, Elahi M, Nishioka K, Oji Y, Matsumoto SE, Li Y, Yoshino H, Mogushi K, Hatano T, Sato T, Ikura T, Ito N, Motoi Y, Hattori N.
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 19
- DOI
  10.1016/j.neurobiolaging.2019.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-18K06198
[Journal Article] Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome2019
- Author(s)
  Borna NN, Kishita Y, Kohda M, Lim SC, Shimura M, Wu Y, Mogushi K, Yatsuka Y, Harashima H, Hisatomi Y, Fushimi T, Ichimoto K, Murayama K, Ohtake A, Okazaki Y.
- Journal Title
  
  neurogenetics
  
  Volume: 20(1) Pages: 9-25
- DOI
  10.1007/s10048-018-0561-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-17F17714, KAKENHI-PROJECT-16K09973
[Journal Article] Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity.,2019
- Author(s)
  Matsumura Y, Ito Y, Mezawa Y, Sulidan K, Daigo Y, Hiraga T, Mogushi K, Wali N, Suzuki H, Itoh T, Miyagi Y, Yokose T, Shimizu S, Takano A, Terao Y, Saeki H, Ozawa M, Abe M, Takeda S, Okumura K, Habu S, Hino O, Takeda K, Hamada M, Orimo A.
- Journal Title
  
  Life Sci. Alliance
  
  Volume: 2(4):e201900425. Pages: 1-24
- DOI
  10.26508/lsa.201900425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K07207, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-19K07884, KAKENHI-PROJECT-18K19656, KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-19H03559, KAKENHI-PROJECT-18K19483, KAKENHI-PROJECT-19K21278, KAKENHI-PROJECT-16H05879
[Journal Article] Estrogen Receptor-positive Ductal Carcinoma In Situ Frequently Overexpresses HER2 Protein Without Gene Amplification.2019
- Author(s)
  Horimoto Y, Terao T, Tsutsumi Y, Tanabe M, Mogushi K, Hlaing MT, Sasaki R, Saeki H, Okazaki M, Sonoue H, Arakawa A, Saito M.
- Journal Title
  
  The American Journal of Surgical Pathology
  
  Volume: 43(9) Pages: 1221-1228
- DOI
  10.1097/pas.0000000000001300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K16287
[Journal Article] FABP4 overexpressed in intratumoral hepatic stellate cells within hepatocellular carcinoma with metabolic risk factors.2018
- Author(s)
  Chiyonobu N、Shimada S、Akiyama Y、Mogushi K、Itoh M、Akahoshi K、Matsumura S、Ogawa K、Ono H、Mitsunori Y、Ban D、Kudo A、Arii S、Suganami T、Yamaoka S、Ogawa Y、Tanabe M、Tanaka S
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 188 Pages: 1213-1224
- DOI
  10.1016/j.ajpath.2018.01.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08732, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PUBLICLY-17H05500, KAKENHI-PROJECT-16H05171, KAKENHI-PROJECT-16KT0110
[Journal Article] Elucidation of inhibitory effects on metastatic sentinel lymph nodes of breast cancer during One-Step Nucleic Acid Amplification2018
- Author(s)
  Horimoto Y, Tanabe M, Kazuno S, Miura Y, Mogushi K, Sonoue H, Arakawa A, Kajino K, Kobayashi T, Saito M.
- Journal Title
  
  Scientific Reports
  
  Volume: 8(1):7563 Pages: 1-7
- DOI
  10.1038/s41598-018-25911-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798
[Journal Article] Tumor sidedness and enriched gene groups for efficacy of first-line cetuximab treatment in metastatic colorectal cancer.2018
- Author(s)
  Sunakawa Y, Mogushi K, Lenz HJ, Zhang W, Tsuji A, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Ichikawa W.　et al
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 17(12) Pages: 2788-2795
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08798
[Journal Article] <i>KCTD12</i> is negatively regulated by Kit in gastrointestinal stromal tumors2018
- Author(s)
  Suehara Y, Akaike K, Mukaihara K, Kurisaki-Arakawa A, Kubota D, Okubo T, Mitomi H, Mitani K, Takahashi M, Toda-Ishii M1, Kim Y, Tanabe Y, Takagi T, Hayashi T, Mogushi K, Kaneko K, Yao T, Saito T.
- Journal Title
  
  Oncotarget
  
  Volume: 9(43) Pages: 27016-27026
- DOI
  10.18632/oncotarget.25469
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K08730, KAKENHI-PROJECT-17K10987, KAKENHI-PROJECT-18K06198, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K15329, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-16K20070
[Journal Article] Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer2018
- Author(s)
  Sunakawa Y, Mogushi K, Lenz HJ, Zhang W, Tsuji A, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Segawa Y, Tanioka H, Negoro Y, Moran M, Astrow SH, Hsiang J, Stephens C, Fujii M, Ichikawa W.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 17 Pages: 2788-2795
- DOI
  10.1158/1535-7163.mct-18-0694
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09333, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K06198
[Journal Article] GCH1 mutations in dopa-responsive dystonia and Parkinson’s disease.2018
- Author(s)
  Yoshino H, Nishioka K, Li Y, Oji Y, Oyama G, Hatano T, Machida Y, Shimo Y, Hayashida A, Ikeda A, Mogushi K, Shibagaki Y, Hosaka A, Iwanaga H, Fujitake J, Ohi T, Miyazaki D, Sekijima Y, Oki M, Kusaka H, Fujimoto KI Ugawa Y, Funayama M, Hattori N.
- Journal Title
  
  J Neurol.
  
  Volume: 265(8) Pages: 1860-1870
- DOI
  10.1007/s00415-018-8930-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-16K09700
[Journal Article] Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic neuroendocrine tumors.2018
- Author(s)
  Ueda H, Akiyama Y, Shimada S, Mogushi K, Serizawa M, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.
- Journal Title
  
  Endocrine-Related Cancer
  
  Volume: 25(6) Pages: 619-631
- DOI
  10.1530/erc-17-0328
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-15H04926
[Journal Article] COQ2 variants in Parkinson's disease and multiple system atrophy.2018
- Author(s)
  Mikasa M, Kanai K, Li Y, Yoshino H, Mogushi K, Hayashida A, Ikeda A, Kawajiri S, Okuma Y, Kashihara K, Sato T, Kondo H, Funayama M, Nishioka K, Hattori N.
- Journal Title
  
  Journal of Neural Transmission
  
  Volume: - Pages: 937-944
- DOI
  10.1007/s00702-018-1885-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09676, KAKENHI-PROJECT-26461319, KAKENHI-PROJECT-15KK0354, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-17K09811, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-18K08798, KAKENHI-PROJECT-16K09678, KAKENHI-PROJECT-16K09700
[Journal Article] Non-small cell lung carcinoma with diffuse co-expression of thyroid transcription factor-1 and ΔNp63/p40.2018
- Author(s)
  Hayashi Takuo、Takamochi Kazuya、Yanai Yuka、Mitani Keiko、Tomita Hisashi、Mogushi Kaoru、Suehara Yoshiyuki、Takahashi Fumiyuki、Suzuki Kenji、Saito Tsuyoshi、Yao Takashi
- Journal Title
  
  Hum Pathol
  
  Volume: S0046-8177 Pages: 177-181
- DOI
  10.1016/j.humpath.2018.01.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09230, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15670, KAKENHI-PROJECT-15KK0353, KAKENHI-PROJECT-15H04964, KAKENHI-PROJECT-26461200, KAKENHI-PROJECT-16K10476, KAKENHI-PROJECT-18K08798
[Journal Article] Molecular and clinical features of the <i>TP53</i> signature gene expression profile in early-stage breast cancer2018
- Author(s)
  Yamaguchi S, Takahashi S, Mogushi K, Izumi Y, Nozaki Y, Nomizu T, Kakugawa Y, Ishida T, Ohuchi N, Ishioka C, Kato S.
- Journal Title
  
  Oncotarget. 9(18):14193-14206.
  
  Volume: 9(18) Pages: 14193-14206
- DOI
  10.18632/oncotarget.24447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-15K06851, KAKENHI-PROJECT-15K10081, KAKENHI-PROJECT-16K11029
[Journal Article] ARID2 modulates DNA damage response in human hepatocellular carcinoma cells2017
- Author(s)
  Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S.
- Journal Title
  
  J Hepatol.
  
  Volume: in press Pages: 942-951
- DOI
  10.1016/j.jhep.2016.12.026
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10421, KAKENHI-PROJECT-17K10653, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926
[Journal Article] Clinical significance of methylation and reduced expression of the quaking gene in colorectal cancer2017
- Author(s)
  Iwata N, Ishikawa T, Okazaki S, Mogushi K, Baba H, Ishiguro M, Kobayashi H, Tanaka H, Kawano T, Sugihara K, Uetake H.
- Journal Title
  
  Anticancer Res
  
  Volume: 37(2) Pages: 489-498
- DOI
  10.21873/anticanres.11341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10552
[Journal Article] Promoter-level transcriptome in primary lesion of endometrial cancer identified biomarkers associated with lymph node metastasis2017
- Author(s)
  Yoshida E, Terao Y, Hayashi N, Mogushi K, Arakawa A, Tanaka Y, Ito Y, Ohmiya H, Hayashizaki Y, Takeda S, Itoh M, Kawaji H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7(1):14160 Pages: 14160-14160
- DOI
  10.1038/s41598-017-14418-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-15K10732
[Journal Article] Acquired Resistance with Epigenetic Alterations Under Long-Term Antiangiogenic Therapy for Hepatocellular Carcinoma2017
- Author(s)
  Ohata Y, Akiyama Y, Shimada S, Mogushi K, Nakao K, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Tanabe M, Tanaka S.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: in press Pages: 1155-1165
- DOI
  10.1158/1535-7163.mct-16-0728
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-16K10421, KAKENHI-PROJECT-17K10689, KAKENHI-PROJECT-16H02670
[Journal Article] Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer.2017
- Author(s)
  Satoh M, Takano S, Sogawa K, Noda K, Yoshitomi H, Ishibashi M, Mogushi K, Takizawa H, Otsuka M, Shimizu H, Miyazaki M, Nomura F.
- Journal Title
  
  Cancer Science.
  
  Volume: 印刷中 Pages: 795-803
- DOI
  10.1111/cas.13181
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04925, KAKENHI-PROJECT-26293299, KAKENHI-PROJECT-26460505, KAKENHI-PROJECT-15K08610, KAKENHI-PROJECT-16K15607, KAKENHI-PROJECT-17K10652, KAKENHI-PROJECT-17KT0124
[Journal Article] LSD1/KDM1 isoform LSD1+8a contributes to neural differentiation in small cell lung cancer.2017
- Author(s)
  Jotatsu, T., Yagishita, S., Tajima, K., Takahashi, F., Mogushi, K., Hidayat, M., Wirawan, A., Ko, R., Kanemaru, R., Shimada, N., Mitani, K., Saito, T., Takamochi, K., Suzuki, K., Kohsaka, S., Kojima, S., Mukae, H., Yatera, K., and Takahashi, K.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: ９ Pages: 86-94
- DOI
  10.1016/j.bbrep.2016.11.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09586, KAKENHI-PROJECT-17K09669, KAKENHI-PROJECT-16K15625
[Journal Article] Correlation of EGFR or KRAS mutation status with 18F-FDG uptake on PET-CT scan in lung adenocarcinoma.2017
- Author(s)
  Takamochi K, Mogushi K, Kawaji H, Imashimizu K, Fukui M, Oh S, Itoh M, Hayashizaki Y, Ko W, Akeboshi M, Suzuki K.
- Journal Title
  
  PLoS One
  
  Volume: 12(4):e0175622.
- DOI
  10.1371/journal.pone.0175622
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10035
[Journal Article] CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells2016
- Author(s)
  Katsuta, E., Tanaka, S., Mogushi, K., Shimada, S., Akiyama, Y., Aihara, A., Matsumura, S., Mitsunori, Y., Ban, D., Ochiai, T., Kudo, A., Fukamachi, H., Tanaka, H., Nakayama, K., Arii, S., Tanabe, M.
- Journal Title
  
  Int J Oncol.
  
  Volume: 48 Pages: 657-659
- DOI
  10.3892/ijo.2015.3299
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25462082, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-26462025
[Journal Article] Novel biomarkers that assist in accurate discrimination of squamous cell carcinoma from adenocarcinoma of the lung2016
- Author(s)
  Kazuya Takamochi, Hiroko Ohmiya, Masayoshi Itoh, Kaoru Mogushi, Tsuyoshi Saito, Kieko Hara, Keiko Mitani, Yasushi Kogo, Yasunari Yamanaka, Jun Kawai, Yoshihide Hayashizaki, Shiaki Oh, Kenji Suzuki, Hideya Kawaji
- Journal Title
  
  BMC cancer
  
  Volume: 16:760 Pages: 1-10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10552
[Journal Article] Expression of connective tissue growth factor in the livers of non-viral hepatocellular carcinoma patients with metabolic risk factors2016
- Author(s)
  Katsuta E, Tanaka S, Mogushi K, Shimada S, Akiyama Y, Aihara A, Matsumura S, Mitsunori Y, Ban D, Ochiai T, Kudo A, Fukamachi H, Tanaka H, Nakayama K, Arii S, Tanabe M.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 48 Pages: 910-22
- DOI
  10.1007/s00535-015-1159-8
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-26870175
[Journal Article] Characterizing Genetic Transitions of Copy Number Alterations and Allelic Imbalances in Oral Tongue Carcinoma Metastasis.2016
- Author(s)
  Morita T, Uzawa N, Mogushi K, Sumino J, Michikawa C, Takahashi KI, Myo K, Izumo T, Harada K
- Journal Title
  
  Genes Chromosomes Cancer.
  
  Volume: 55 Pages: 975-986
- DOI
  10.1002/gcc.22395
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861913, KAKENHI-PROJECT-26861704, KAKENHI-PROJECT-26861705, KAKENHI-PROJECT-15K11288
[Journal Article] Overexpression of the S100A2 protein as a prognostic marker for patients with stage II and III colorectal cancer.2016
- Author(s)
  Masuda T, Ishikawa T, Mogushi K, Okazaki S, Ishiguro M, Iida S, Mizushima H, Tanaka H, Uetake H, Sugihara K.
- Journal Title
  
  Int J Oncol. 2016 Mar;48(3):975-82..
  
  Volume: 48(3) Pages: 975-982
- DOI
  10.3892/ijo.2016.3329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10035
[Journal Article] Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model.2015
- Author(s)
  Aikawa T, Mogushi K, Iijima-Tsutsui K, Ishikawa K, Sakurai　H, Tanaka H, Mizusawa H, Watase K
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 24（17） Pages: 4780-4791
- DOI
  10.1093/hmg/ddv202
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-26860661, KAKENHI-PROJECT-25282241
[Journal Article] Identification of a gene associated with autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study2015
- Author(s)
  Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Yuanzhe L, Ogaki K, Ando M, Yoshinon H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N.
- Journal Title
  
  The Lancet Neurology
  
  Volume: 14 Pages: 274-282
- DOI
  10.1016/s1474-4422(14)70266-2
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22129006, KAKENHI-PROJECT-24390224, KAKENHI-PROJECT-24500868, KAKENHI-PROJECT-24790903, KAKENHI-PUBLICLY-25110720, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111007, KAKENHI-PUBLICLY-25129707, KAKENHI-PROJECT-25461291, KAKENHI-PROJECT-25461292, KAKENHI-PROJECT-25670420, KAKENHI-PROJECT-25713015, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-15K10050, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111003, KAKENHI-PLANNED-23111004, KAKENHI-PROJECT-25257507, KAKENHI-PROJECT-15H04842, KAKENHI-PROJECT-25860725, KAKENHI-PROJECT-25305030
[Journal Article] Prognostic significance of Traf2-and Nck- interacting kinase (TNIK) in colorectal cancer.2015
- Author(s)
  Takahashi H, Ishikawa T, Ishiguro M, Okazaki S, Mogushi K, Kobayashi H, Iida S, Mizushima H, Tanaka H, Uetake H, Sugihara K.
- Journal Title
  
  BMC Cancer
  
  Volume: 15 Pages: 794-794
- DOI
  10.1186/s12885-015-1783-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870175
[Journal Article] Distinct clinicopathological phenotype of hepatocellular carcinoma with ethoxybenzyl-magnetic resonance imaging hyperintensity: association with gene expression signature.2015
- Author(s)
  Miura T, Ban D, Tanaka S, Mogushi K, Kudo A, Matsumura S, Mitsunori Y, Ochiai T, Tanaka H, Tanabe M.
- Journal Title
  
  Am J Surg
  
  Volume: 210 Pages: 561-569
- DOI
  10.1016/j.amjsurg.2015.03.027
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25462082
[Journal Article] Mitochondrial metabolism in the noncancerous liver determine the occurrence of hepatocellular carcinoma: a prospective study.2014
- Author(s)
  Kudo A, Mogushi K, Takayama T, Matsumura S, Ban D, Irie T, Ochiai T, Nakamura N, Tanaka H, Anzai N, Sakamoto M, Tanaka S, Arii S.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 49 Pages: 502-10
- DOI
  10.1007/s00535-013-0791-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591868, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PROJECT-26870175
[Journal Article] Involvement of MAP3K8 and miR-17-5p in poor virologic response to interferon-based combination therapy for chronic hepatitis C.2014
- Author(s)
  Tsubota A, Mogushi K, Aizaki H, Miyaguchi K, Nagatsuma K, Matsudaira H, Kushida T, Furihata T, Tanaka H, Matsuura T.
- Journal Title
  
  PLoS One.
  
  Volume: 9
- DOI
  10.1371/journal.pone.0097078
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23590995, KAKENHI-PROJECT-24591001, KAKENHI-PROJECT-26870175
[Journal Article] Age-related clinicopathologic and molecular features of patients receiving curative hepatectomy for hepatocellular carcinoma.2014
- Author(s)
  Katsuta E, Tanaka S, Mogushi K, Matsumura S, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Tanaka H, Tanabe M, Arii S.
- Journal Title
  
  Am J Surg
  
  Volume: 208(3) Pages: 450-456
- DOI
  10.1016/j.amjsurg.2014.01.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22130005, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PROJECT-26870175
[Journal Article] Visualization of stem cell features in human hepatocellular carcinoma reveals in vivo significance of tumor-host interaction and clinical course.2013
- Author(s)
  Muramatsu S
- Journal Title
  
  Hepatology
  
  Volume: 58 Pages: 218-228
- DOI
  10.1002/hep.26345
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130005, KAKENHI-PROJECT-22249050, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PLANNED-22117004
[Journal Article] Contrast-enhanced intraoperative ultrasonography for vascular imaging of hepatocellular carcinoma: clinical and biological significance.2013
- Author(s)
  Sato K
- Journal Title
  
  Hepatology
  
  Volume: 57 Pages: 1436-1447
- DOI
  10.1002/hep.26122
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-22249050, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-25290070, KAKENHI-PLANNED-22130005
[Journal Article] PathAct: a novel method for pathway analysis using gene expression profiles.2013
- Author(s)
  Mogushi K, Tanaka H.
- Journal Title
  
  Bioinformation
  
  Volume: 9 Pages: 394-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290070
[Presentation] Gene expression analysis and cancer signaling networks2017
- Author(s)
  Kaoru Mogushi
- Organizer
  International Symposium on BioComplexity
- Place of Presentation
  B-Conプラザ (別府)
- Year and Date
  2017-01-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870175
[Presentation] 小細胞肺がんにおけるヒストン脱メチル化酵素LSD1+8aの役割2016
- Author(s)
  Aditya Wirawan、田島健、丈達陽順、柳下薫寛、高遼、Moulid Hidayat、金丸良太、濃沼淑芳、井原宏彰、嶋田奈緒子、茂櫛薫、高橋史行、高橋和久
- Organizer
  第57回日本肺癌学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-16K09586
[Presentation] 舌癌同一患者における原発巣－転移リンパ節間の全ゲノムコピー数異常の比較2015
- Author(s)
  森田琢磨、鵜澤成一、茂櫛薫、名生邦彦、高橋謙一郎、道川千絵子、炭野淳、出雲俊之、原田清
- Organizer
  第５３回日本癌治療学会学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-15K11288
[Presentation] A novel method for pathway analysis using gene expression profiles2013
- Author(s)
  茂櫛薫、田中博
- Organizer
  CBI学会2013年大会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-25290070

1. 小見山博光 (30348982)

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2. 加藤俊介 (40312657)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. Tajima Ken (50384102)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 高橋史行 (70327823)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. 高橋和久 (80245711)

# of Collaborated Projects: 3 results

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6. TSUBOTA Akihito (90322643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Tanaka Hiroshi (60155158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. Tanaka Shinji (30253420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
9. Morioka Katuki (30351589)

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10. TAKAHSHI Makoto (40445549)

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11. KAMIYAMA HIROHIKO (00365595)

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12. UZAWA NARIKAZU (30345285)

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13. Okuzawa Atsushi (00348913)

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14. 坂本啓 (00302886)

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15. 島田周 (20609705)

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16. 柳沼行宏 (60338415)

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17. ITO Michiko

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# of Collaborated Products: 3 results
18. SUGANAMI takayoshi

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# of Collaborated Products: 2 results
19. SATAKE Wataru

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# of Collaborated Products: 1 results
20. NORIHIKO Furuya

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# of Collaborated Products: 1 results
21. FUNAYAMA Manabu

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# of Collaborated Products: 3 results
22. TOMIYAMA Hiroyuki

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# of Collaborated Products: 1 results
23. KAWAJI Hideya

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# of Collaborated Products: 1 results
24. ITOH Masayoshi

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# of Collaborated Products: 1 results
25. TAKEDA Satoru

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# of Collaborated Products: 1 results
26. HAYASHIZAKI Yoshihide

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# of Collaborated Products: 1 results
27. SAITO Tsuyoshi

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# of Collaborated Products: 5 results
28. KUBOTA Daisuke

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29. MUKAIHARA Kenta

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30. AKAIKE Keisuke

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31. ISHII Midori

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32. SUEHARA Yoshiyuki

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33. Hayashi Takuo

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34. Tanabe Yu

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35. SHIMIZU Shimizu

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36. HATANO Taku

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# of Collaborated Products: 1 results
37. IKEDA aya

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38. TAKAHASHI Shin

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39. YAMAGUCHI Shigeo

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40. OKAZAKI Yasushi

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41. OHTAKE Akira

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42. MURAYAMA Kei

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43. TAKANO Atsushi

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44. 藍原有弘

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45. 秋山好光

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46. 落合高徳

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47. 田辺稔

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48. 落合匠

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49. 伴大輔

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50. 工藤篤

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51. 相川知徳

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52. 水澤英洋

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53. 渡瀬啓

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54. 中村典明

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55. 戸田達史

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56. 服部信孝

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57. 天羽拓

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58. 斉木臣二

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59. 内山安男

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60. 大野博司

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61. 李元哲

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62. 西岡健弥

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63. 大江賢治

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64. 佐々木光穂

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65. 葛原茂樹

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66. 小久保康昌

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67. 寺尾泰久

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68. 深町博史

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70. 相崎英樹

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73. 有井滋樹

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74. 宮崎勝

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75. 吉富秀幸

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76. 高野重紹

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77. 佐藤守

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78. 小川祥二郎

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79. 野村文夫

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80. 傳田忠道

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82. 小島豊

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84. 名生邦彦

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85. 炭野淳

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86. 道川千絵子

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87. 角川陽一郎

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88. LIM SZE CHERN

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89. 岡崎康司

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90. 木下善仁

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91. ワリナディラ

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92. 折茂彰

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93. 醍醐弥太郎

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94. 平賀徹

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95. 竹田和由

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96. 伊藤匠

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97. 浜田道昭

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98. 堀本義哉

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Mogushi Kaoru 茂櫛 薫

MOGUSHI Kaoru 茂櫛 薫

Research Projects

Research Products

Co-Researchers

Development and its application of the "virtual dissection" method using gene expression profiles of clinical specimensPrincipal InvestigatorOngoing

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胸腺癌における新規治療標的遺伝子異常の探索Ongoing

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CAGE発現解析を用いた大腸がん肺転移予測マーカーの特定Ongoing

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小細胞肺癌における新規治療標的遺伝子異常の解析Ongoing

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Identification of biomaker for predicting liver metastasis of colorectal cancer with CAGE analysisOngoing

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Inactivation of tumor suppressor by histone methylation in lung cancer

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Development of biomarker for detection of lymphnode metastasis and prediction of recurrence in colorectal cancer using CAGE analysis

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Searching for miRNA as a biomarker in blood colorectal cancer in blood to evaluate sensitivities against chemotherapies for colorectal cancer

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Construction of personalized monitoring system for colorectal caner using circulating tumor DNA

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Study on formation and evaluation method of intratumoral heterogeneity in oral cancer

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System-based drug discovery database using partial least square regressionPrincipal Investigator

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Identification and clinical application of pathway-based markers for cancer

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Functional analysis of oxidative stress-induced hepatocarcinogenic genes for molecular target treatment

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Mogushi Kaoru 茂櫛薫

MOGUSHI Kaoru 茂櫛薫