Hashimoto Masakazu 橋本昌和

… Alternative Names

HASHIMOTO Masakazu 橋本昌和

橋本昌和ハシモトマサカズ

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Researcher Number	60580496
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 福島県立医科大学, 医学部, 准教授 2021 – 2023: 大阪大学, 大学院生命機能研究科, 准教授 2019 – 2021: 大阪大学, 生命機能研究科, 准教授 2015 – 2018: 大阪大学, 生命機能研究科, 助教 2014: 千葉大学, 医学(系)研究科(研究院), 助教 2011: National Institute for Basic Biology, 研究員 2010: 基礎生物学研究所, 形態形成研究部門, 特別協力研究員
Review Section/Research Field	Principal Investigator Developmental biology / Biological Sciences / Basic Section 44020:Developmental biology-related / Transformative Research Areas, Section (III) / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
Keywords	Principal Investigator エピブラスト / 細胞競合 / 割球間競合 / ゲノム編集 / 平面内細胞極性 / 一卵性双生児 / 全能性 / 割球間細胞競合 / 多能性 / 細胞死 … More / 個体発生 / Hippoシグナル / Tead活性 / 顔面形成 / 収斂伸長 / 鼻 / 軟骨細胞 / 原腸陥入 Less

エピブラストにおける次世代ゲノムのリスクマネジメント戦略Principal Investigator
- Principal Investigator
  
  橋本昌和
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Fukushima Medical University
体細胞突然変異からひも解く一卵性双生児の発生遺伝学Principal Investigator
- Principal Investigator
  
  橋本昌和
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Fukushima Medical University
マウス着床前胚におけるエピブラスト形成機構の解明Principal Investigator
- Principal Investigator
  
  橋本昌和
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Fukushima Medical University
  Osaka University
マウス母体内における2細胞期胚の割球間競合の抑制機構と意義の解明Principal Investigator
- Principal Investigator
  
  橋本昌和
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
受精後の精子尾部が与える全能性への影響の解明Principal Investigator
- Principal Investigator
  
  橋本昌和
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
マウス個体発生におけるTead/Yap依存的細胞競合に関する研究Principal Investigator
- Principal Investigator
  
  橋本昌和
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osaka University
The study of cell competition in mouse developmentPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Masakazu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Osaka University
The roles of planar cell polarity in non-epithelial tissuesPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Masakazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Osaka University
  Chiba University
個体発生および脳機能における平面内細胞極性因子の役割の解明Principal Investigator
- Principal Investigator
  
  橋本昌和
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Developmental biology
- Research Institution
  National Institute for Basic Biology

All 2023 2022 2020 2019 2018 2017 2016 2015 2010

All Journal Article Presentation

[Journal Article] Cell competition controls differentiation in mouse embryos and stem cells2020
- Author(s)
  Hashimoto Masakazu、Sasaki Hiroshi
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 67 Pages: 1-8
- DOI
  10.1016/j.ceb.2020.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06687, KAKENHI-PUBLICLY-19H04778, KAKENHI-PROJECT-19K22427
[Journal Article] Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse.2016
- Author(s)
  Hashimoto M, Yamashita Y, Takemoto T.
- Journal Title
  
  Developmental Biology
  
  Volume: 418 Issue: 1 Pages: 1-9
- DOI
  10.1016/j.ydbio.2016.07.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670092, KAKENHI-PROJECT-26840075, KAKENHI-PROJECT-16K14738, KAKENHI-PROJECT-16K18550
[Journal Article] Somatic cell reprogramming-free generation of genetically modified pigs.2016
- Author(s)
  Tanihara F, Takemoto T, Kitagawa E, Rao S, Do LT, Onishi A, Yamashita Y, Kosugi C, Suzuki H, Sembon S, Suzuki S, Nakai M, Hashimoto M, Yasue A, Matsuhisa M, Noji S, Fujimura T, Fuchimoto D, Otoi T.
- Journal Title
  
  Sci Adv
  
  Volume: 14 Issue: 9
- DOI
  10.1126/sciadv.1600803
- NAID
  120006240045
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05551, KAKENHI-PROJECT-26840075
[Journal Article] Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR/Cas9-based genome editing.2015
- Author(s)
  Hashimoto M. and Takemoto T.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 11315-11315
- DOI
  10.1038/srep11315
- NAID
  120006875680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670092, KAKENHI-PROJECT-26840075, KAKENHI-PROJECT-24687029
[Presentation] Understanding the mechanisms of epiblast formation and its application to the regenerative medicine2023
- Author(s)
  Masakazu Hashimoto
- Organizer
  The 1st JST International Symposium on Dynamics of Cellular Interactions in Multicellular Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27181
[Presentation] Understanding the mechanisms of epiblast formation and its application to the regenerative medicine2023
- Author(s)
  Masakazu Hashimoto
- Organizer
  The 1st JST International Symposium on Dynamics of Cellular Interactions in Multicellular Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04673
[Presentation] マウス着床前胚におけるエピブラスト形成機構2022
- Author(s)
  橋本昌和
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H05366
[Presentation] How is the epiblast established in the mouse pre-implantation embryo?2022
- Author(s)
  橋本昌和
- Organizer
  第55回日本発生生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06687
[Presentation] How is the epiblast established in the mouse pre-implantation embryo?2022
- Author(s)
  橋本昌和
- Organizer
  第55回日本発生生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H05366
[Presentation] マウス着床前胚におけるエピブラスト形成機構2022
- Author(s)
  橋本昌和
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06687
[Presentation] 細胞競合を介したマウスエピブラスト形成機構2019
- Author(s)
  橋本昌和
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06687
[Presentation] Tead-Yap activity in inner cell mass promotes naive pluripotency and its variation triggers cell competition to establish high quality epiblast2018
- Author(s)
  Masakazu Hashimoto
- Organizer
  Joint Annual Meeting of 51st JSDB and 70th JSCB
- Data Source
  KAKENHI-PROJECT-16K18550
[Presentation] マウス着床前胚のエピブラストはTead/Yap活性依存的な選択的細胞死を経て多能性を均質化させる2017
- Author(s)
  橋本昌和、竹之下憂祐、百合祐樹、佐々木洋
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K18550
[Presentation] The Role of Tead activity-dependent cell competition in mouse early development2017
- Author(s)
  Masakazu Hashimoto, Yusuke Takenoshita, Yuki Yuri, Hiroshi Sasaki
- Organizer
  細胞競合国際シンポジウム
- Data Source
  KAKENHI-PROJECT-16K18550
[Presentation] マウス初期胚における細胞競合の解析2016
- Author(s)
  橋本昌和、竹之下憂祐、百合祐樹、佐々木洋
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K18550
[Presentation] 個体発生における平面内細胞極性の役割2010
- Author(s)
  橋本昌和
- Organizer
  発生生物学会夏季シンポジウム
- Place of Presentation
  八王子セミナーハウス(東京都)
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22870019

1. TAKEMOTO Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 泰江章博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Masakazu 橋本 昌和

HASHIMOTO Masakazu 橋本 昌和

橋本 昌和 ハシモト マサカズ

Research Projects

Research Products

Co-Researchers

エピブラストにおける次世代ゲノムのリスクマネジメント戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

体細胞突然変異からひも解く一卵性双生児の発生遺伝学Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マウス着床前胚におけるエピブラスト形成機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マウス母体内における2細胞期胚の割球間競合の抑制機構と意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

受精後の精子尾部が与える全能性への影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マウス個体発生におけるTead/Yap依存的細胞競合に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of cell competition in mouse developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of planar cell polarity in non-epithelial tissuesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

個体発生および脳機能における平面内細胞極性因子の役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cell competition controls differentiation in mouse embryos and stem cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Somatic cell reprogramming-free generation of genetically modified pigs.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR/Cas9-based genome editing.2015

Author(s)

Journal Title

DOI

Hashimoto Masakazu 橋本昌和

HASHIMOTO Masakazu 橋本昌和

橋本昌和ハシモトマサカズ