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Okinaga Toshinori  沖永 敏則

… Alternative Names

OKINAGA Toshinori  沖永 敏則

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Researcher Number 60582773
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-0598-5246
Affiliation (Current) 2025: 大阪歯科大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 大阪歯科大学, 歯学部, 教授
2017: 九州歯科大学, 健康増進学講座感染分子生物学分野, 講師
2014 – 2017: 九州歯科大学, 歯学部, 講師
2011 – 2013: 九州歯科大学, 歯学部, 助教
2012: 九州歯科大学, 歯学科・感染分子生物学分野, 助教
Review Section/Research Field
Principal Investigator
Pathobiological dentistry/Dental radiology / Basic Section 57020:Oral pathobiological science-related
Except Principal Investigator
Basic Section 57080:Social dentistry-related / Pathobiological dentistry/Dental radiology / Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 57020:Oral pathobiological science-related / Periodontology / Social dentistry
Keywords
Principal Investigator
マクロファージ / ピロトーシス / 炎症性サイトカイン / 歯周病細菌 / インフラマソーム / 炎症 / 膜小胞 / 免疫細胞 / 細菌叢 / 口腔細菌 … More / プロポリス / プラーク / 不飽和脂肪酸 / 脂肪酸 / GasderminD / サイトカイン / オメガ3系脂肪酸 / 自然免疫 / 宿主寄生体相互関係 / 歯周病原細菌 / 心血管疾患 / クオラムセンシング / 歯周病原性細菌 / 歯周病と全身疾患 / 感染 / 免疫 … More
Except Principal Investigator
細菌叢 / 口腔健康 / 口腔細菌叢 / 高齢者 / インフラマソーム / マクロファージ / 光線力学療法 / インプラント周囲炎 / ポルフィリン類 / ポルフィリン / ウイルス性呼吸器感染症 / 口腔細菌 / 舌苔 / ゲノム解析 / メタゲノム解析 / 細菌ゲノム解析 / 口腔菌叢バランス / 遺伝子改変 / Rothia属細菌 / 硝酸還元菌 / 口腔善玉菌 / 泡沫化 / ピロトーシス / 心筋梗塞 / 歯周病 / 動脈硬化 / 慢性歯周炎 / AIM / 共益因子 / 炎症性骨吸収 / スフェロイド / 共役因子 / 骨リモデリング / サイトカイン / 血管流路 / 最大呼気量 / 歯周疾患 / 口腔ケア / 菌叢解析 / 栄養 / apelin / 身体活動 / dectin-1 / β1-3グルカン Less
  • Research Projects

    (13 results)
  • Research Products

    (148 results)
  • Co-Researchers

    (22 People)
  •  Microbiota transition to a healthy form of peri-implantitis with super-selective photodynamic therapy

    • Principal Investigator
      草野 薫
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Osaka Dental University
  •  プレバイオティクスを見据えた細菌叢と免疫細胞の偏移に関わる物質探索Principal Investigator

    • Principal Investigator
      沖永 敏則
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Osaka Dental University
  •  ウイルス性呼吸器感染症予防に向けた口腔細菌叢によるポルフィリン類産生機構の解明

    • Principal Investigator
      高橋 一也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Osaka Dental University
  •  Construction of a novel oral health indicator based on an oral microbiota culture model

    • Principal Investigator
      Mashimo Chiho
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Osaka Dental University
  •  Exploratory study of factors inducing tongue microbiota transition in the elderly for the prevention of pneumonia

    • Principal Investigator
      TAKAHASHI Kazuya
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Osaka Dental University
  •  Mechanisms involved in pathogenesis of myocardial infarction by foam cell formation and inflammasome activation

    • Principal Investigator
      Tatsuji Nishihara
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Kyushu Dental College
  •  Molecular biological analysis on periodontal disease and obesity centered on fat metabolism analysis of bacterial invaded macrophagesPrincipal Investigator

    • Principal Investigator
      OKINAGA TOSHINORI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kyushu Dental College
  •  Role of apelin on mechanisms to improve state of periodontitis by physical activity and its application to preventive dentistry

    • Principal Investigator
      Akifusa Sumio
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Social dentistry
    • Research Institution
      Kyushu Dental College
  •  Eluciation for coupling factors for bone remodeling using 3-D spheroid culture system

    • Principal Investigator
      Tastuji Nishihara
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kyushu Dental College
  •  The effect of AIM for periodontitis and body

    • Principal Investigator
      Morishita Masaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontology
    • Research Institution
      Kyushu Dental College
  •  Analysis of the inflammatory mechanism in host-parasite relationship through inflammasome activityPrincipal Investigator

    • Principal Investigator
      OKINAGA TOSHINORI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kyushu Dental College
  •  Development of biopolymer compound to elucidate the effect of glucan on innate immune system

    • Principal Investigator
      NISHIHARA Tatsuji
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kyushu Dental College
  •  Investigate of the quorum sensing by which cardiovascular disease are influenced by periodontopathic bacterium infectionPrincipal Investigator

    • Principal Investigator
      OKINAGA Toshinori
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Kyushu Dental College

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

  • [Book] 第2回 マクロファージにおける炎症応答でのインフラマソームの役割2012

    • Author(s)
      沖永敏則、西原達次著
    • Publisher
      ヒョーロン
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Book] 文献と臨床の橋わたし 歯周炎におけるマクロファージの機能の多様性 「第2回 マクロファージにおける炎症応答でのインフラマソームの役割2012

    • Author(s)
      沖永敏則、西原達次 (沖永敏則)
    • Total Pages
      3
    • Publisher
      ヒョーロン出版
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Book] 文献と臨床の橋わたし 歯周炎におけるマクロファージの機能の多様性 第2回:マクロファージにおける炎症応答でのインフラマソームの役割2012

    • Author(s)
      沖永敏則、西原達次
    • Total Pages
      3
    • Publisher
      ヒョーロン・パブリッシャーズ
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Journal Article] Transposon insertion in Rothia dentocariosa.2024

    • Author(s)
      Boang Liu, Chiho Mashimo, Takayuki Nambu, Hugo Maruyama, Toshinori Okinaga.
    • Journal Title

      Journal of Oral Biosciences

      Volume: - Issue: 2 Pages: 358-364

    • DOI

      10.1016/j.job.2024.04.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K09518, KAKENHI-PROJECT-19K10456
  • [Journal Article] Effect of Brazilian propolis from the state of Bahia on oral bacteria2023

    • Author(s)
      Takigawa H, Mashimo C, Nambu T, Maruyama H, Okinaga T.
    • Journal Title

      J Osaka Dent Univ.

      Volume: 57 Pages: 125-129

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09954
  • [Journal Article] Effect of blue LED irradiation on the cariogenic bacteria Streptococcus mutans and gingival epithelial cells.2023

    • Author(s)
      Xie Z, Yoshikawa K, Nambu T, Yasuo K, Iwata N, Okinaga T, Yamoto K
    • Journal Title

      J Osaka Dent Univ.

      Volume: 57 Pages: 239-244

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09954
  • [Journal Article] Effect of cell death induced by deferriferrichrysin on oral squamous cell carcinoma cells.2023

    • Author(s)
      Tani M, Okinaga T, Mambu T, Mashimo C, Maruyama H, Iseki T.
    • Journal Title

      J Osaka Dent Univ.

      Volume: 57 Pages: 89-97

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09954
  • [Journal Article] Effect of Brazilian propolis from the state of Bahia on oral bacteria.2023

    • Author(s)
      Hiroki Takigawa, Chiho Mashimo, Takayuki Nambu, Hugo Maruyama, Toshinori Okinaga
    • Journal Title

      Journal of Osaka Dental University

      Volume: 57 Pages: 125-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K10456
  • [Journal Article] Antimicrobial property of Hawaiian propolis against oral pathogenic bacteria2022

    • Author(s)
      Kang W, Maruyama H, Kawano A, Okinaga T
    • Journal Title

      Journal of Osaka Dental University

      Volume: 56 Pages: 161-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09954
  • [Journal Article] Complete Genome Sequence of Actinomyces oris Strain K20, Isolated from an Oral Apical Lesion2022

    • Author(s)
      Nambu Takayuki、Mashimo Chiho、Maruyama Hugo、Taniguchi Makoto、Huang Yao、Takigawa Hiroki、Kang Wenyan、Yan Qianqian、Zhang Lei、Yang Lin、Takahashi Kazuya、Okinaga Toshinori
    • Journal Title

      Microbiology Resource Announcements

      Volume: 11 Issue: 8

    • DOI

      10.1128/mra.00541-22

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10285, KAKENHI-PROJECT-21K10245, KAKENHI-PROJECT-22K09954
  • [Journal Article] Inter-site and interpersonal diversity of salivary and tongue microbiomes, and the effect of oral care tablets.2021

    • Author(s)
      Maruyama H, Masago A, Nambu T, Mashimo C, Takahashi K, Okinaga T.
    • Journal Title

      F1000Research

      Volume: 9 Pages: 1477-1477

    • DOI

      10.12688/f1000research.27502.2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10456
  • [Journal Article] Interdental Plaque Microbial Community Changes under In Vitro Violet LED Irradiation2021

    • Author(s)
      Wang Dan、Nambu Takayuki、Tanimoto Hiroaki、Iwata Naohiro、Yoshikawa Kazushi、Okinaga Toshinori、Yamamoto Kazuyo
    • Journal Title

      Antibiotics

      Volume: 10 Issue: 11 Pages: 1348-1348

    • DOI

      10.3390/antibiotics10111348

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10473, KAKENHI-PROJECT-20K10285
  • [Journal Article] Inter-site and interpersonal diversity of salivary and tongue microbiomes, and the effect of oral care tablets2020

    • Author(s)
      Hugo Maruyama, Ayako Masago, Takayuki Nambu, Chiho Mashimo, Kazuya Takahashi, Toshinori Okinaga
    • Journal Title

      F1000Research

      Volume: 9 Pages: 1477-1477

    • DOI

      10.12688/f1000research.27502.1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10456, KAKENHI-PROJECT-19K10473, KAKENHI-PROJECT-19K10475, KAKENHI-PROJECT-20K10285
  • [Journal Article] Docosahexaenoic acid attenuates cell death and interleukin-1beta secretion in THP-1 cells responded to Aggregatibacter actinomycetemcomitans invasion2020

    • Author(s)
      Kawano Aki, Ariyoshi Wataru, Yamasaki Ryota, Yoshioka Yoshie, Kashiwagi Kosuke, Namikawa Daisuke, Nishihara Tatsuji, Okinaga Toshinori
    • Journal Title

      Biomedical Research

      Volume: 31 Pages: 93-100

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Journal Article] β-glucan suppresses cell death of ASC deficient macrophages invaded by periodontopathic bacteria through the caspase-11 pathway2019

    • Author(s)
      Inoue Maki、Okinaga Toshinori、Usui Michihiko、Kawano Aki、Thongsiri Chuencheewit、Nakashima Keisuke、Ariyoshi Wataru、Nishihara Tatsuji
    • Journal Title

      FEMS Microbiology Letters

      Volume: 366 Issue: 8

    • DOI

      10.1093/femsle/fnz093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09556, KAKENHI-PROJECT-18K09797
  • [Journal Article] The Biological Effects of Interleukin-17A on Adhesion Molecules Expression and Foam Cell Formation in Atherosclerotic Lesions2019

    • Author(s)
      Shiotsugu Shohei、Okinaga Toshinori、Habu Manabu、Yoshiga Daigo、Yoshioka Izumi、Nishihara Tatsuji、Ariyoshi Wataru
    • Journal Title

      Journal of Interferon & Cytokine Research

      Volume: 39 Issue: 11 Pages: 694-702

    • DOI

      10.1089/jir.2019.0034

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09555, KAKENHI-PROJECT-18K09556, KAKENHI-PROJECT-18K09797
  • [Journal Article] Nitric oxide donor modulates a multispecies oral bacterial community - an in vitro study.2019

    • Author(s)
      Takayuki Nambu, Dan Wang, Chiho Mashimo, Hugo Maruyama, Kosuke Kashiwagi, Kazushi Yoshikawa, Kazuyo Yamamoto, Toshinori Okinaga.
    • Journal Title

      Microorganisms

      Volume: 7 Issue: 9 Pages: 353-353

    • DOI

      10.3390/microorganisms7090353

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K10456, KAKENHI-PROJECT-17K15254, KAKENHI-PROJECT-16K11469, KAKENHI-PROJECT-16K11876
  • [Journal Article] Docosahexaenoic acid enhances M2 macrophage polarization via the p38 signaling pathway and autophagy2019

    • Author(s)
      Kawano Aki、Ariyoshi Wataru、Yoshioka Yoshie、Hikiji Hisako、Nishihara Tatsuji、Okinaga Toshinori
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: 印刷中 Issue: 8 Pages: 12604-12617

    • DOI

      10.1002/jcb.28527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09556, KAKENHI-PROJECT-19K10340
  • [Journal Article] Zoledronic acid exacerbates inflammation through M1 macrophage polarization2018

    • Author(s)
      Kaneko Junya、Okinaga Toshinori、Hikiji Hisako、Ariyoshi Wataru、Yoshiga Daigo、Habu Manabu、Tominaga Kazuhiro、Nishihara Tatsuji
    • Journal Title

      Inflammation and Regeneration

      Volume: 38 Issue: 1

    • DOI

      10.1186/s41232-018-0074-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Journal Article] Ky-2, a hybrid compound histone deacetylase inhibitor, regulated inflammatory response in LPS-driven human macrophages2018

    • Author(s)
      Kaneko Junya、Okinaga Toshinori、Ariyoshi Wataru、Hikiji Hisako、Fujii Seiko、Iwanaga Kenjiro、Tominaga Kazuhiro、Nishihara Tatsuji
    • Journal Title

      Cell Biology International

      Volume: 42 Issue: 12 Pages: 1622-1631

    • DOI

      10.1002/cbin.11058

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09556, KAKENHI-PROJECT-16H05545, KAKENHI-PROJECT-16K11698
  • [Journal Article] High molecular weight hyaluronic acid regulates MMP13 expression in chondrocytes via DUSP10/MKP52017

    • Author(s)
      Furuta J, Ariyoshi W, Okinaga T, Takeuchi J, Mitsugi S, Tominaga K, Nishihara T.
    • Journal Title

      J Orthop Res

      Volume: 35 Issue: 12 Pages: 331-339

    • DOI

      10.1002/jcp.25809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-15K11263, KAKENHI-PROJECT-15K11423
  • [Journal Article] Mechanisms involved in enhancement of matrix metalloproteinase-9 expression in macrophages by interleukin-332017

    • Author(s)
      Ariyoshi W, Okinaga T, Chaweewannakorn W, Akifusa S, Nisihara T
    • Journal Title

      J Cell Physiol

      Volume: 20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Journal Article] Ameloblastin and enamelin prevent osteoclast formation by suppressing RANKL expression via MAPK signaling pathway2017

    • Author(s)
      Chaweewannakorn W, Ariyoshi W, Okinaga T, Morikawa K, Saeki K, Maki K, Nishihara T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 485 Issue: 3 Pages: 621-626

    • DOI

      10.1016/j.bbrc.2017.01.181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-15K11263
  • [Journal Article] Ameloblastin Upregulates Inflammatory Response through Induction of IL-1β in Human Macrophages2017

    • Author(s)
      Otsuka M, Okinaga T, Ariyoshi W, Kitamura C, Nishihara T.
    • Journal Title

      J Cell Biochem

      Volume: - Issue: 10 Pages: 3308-3317

    • DOI

      10.1002/jcb.25983

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-26293406
  • [Journal Article] Mature Biofilm Degradation by Potential Probiotics: Aggregatibacter actinomycetemcomitans versus Lactobacillus spp2016

    • Author(s)
      Jaffar N, Ishikawa Y, Mizuno K, Okinaga T, Maeda T
    • Journal Title

      PLos one

      Volume: 11 Issue: 7 Pages: e0159466-e0159466

    • DOI

      10.1371/journal.pone.0159466

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Journal Article] Diagnosis of Periodontal Disease from Saliva Samples Using Fourier Transform Infrared Microscopy Coupled with Partial Least Squares Discriminant Analysis2016

    • Author(s)
      Fujii S, Sato S, Fukuda K, Okinaga T, Ariyoshi W, Usui M, Nakashima K, Nishihara T, Takenaka S.
    • Journal Title

      Anal. Sci.

      Volume: 32 Issue: 2 Pages: 225-231

    • DOI

      10.2116/analsci.32.225

    • NAID

      130005125648

    • ISSN
      0910-6340, 1348-2246
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Journal Article] Lysophosphatidylethanolamina acyltransfcrase/membrane-bound O-acyltransferase 1 regulates morphology and function of P19C6 cell-derived neurons.2016

    • Author(s)
      Tabe S, Hikiji H, Ariyoshi W, Hashidate-Yoshida T, Shindou H,Okinaga T, Shimizu T, Tominaga K,Nishihara T.
    • Journal Title

      FASEB. J

      Volume: 30 Issue: 7 Pages: 2591-2601

    • DOI

      10.1096/fj.201500097r

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05545, KAKENHI-PROJECT-26460380, KAKENHI-PROJECT-15K15696, KAKENHI-PROJECT-15K15746, KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-16K21651
  • [Journal Article] Essential role of mitogen-activated protein kinases in IL-17A-induced MMP-3 expression in human synovial sarcoma cells2016

    • Author(s)
      Sakurai T, Yoshiga D, Ariyoshi W, Okinaga T, Kiyomiya H, Furuta J, Yoshioka I, Tominaga K, Nishihara T
    • Journal Title

      BMC Res Notes

      Volume: 9 (1) Issue: 1 Pages: 68-68

    • DOI

      10.1186/s13104-016-1892-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15696, KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-26861577
  • [Journal Article] Essential Role of Lysophosphatidylcholine Acyltransferase 3 in the Induction of Macrophage Polarization in PMA-Treated U937 Cells2015

    • Author(s)
      Taniguchi K, Hikiji H, Okinaga T, Hashidate-Yoshida T, Shindou H, Ariyoshi W, Shimizu T, Tominaga K, Nishihara T
    • Journal Title

      J Cell Biochem

      Volume: 116 Issue: 12 Pages: 2840-2848

    • DOI

      10.1002/jcb.25230

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11083, KAKENHI-PROJECT-26460380, KAKENHI-PROJECT-15K15746, KAKENHI-PROJECT-26870879, KAKENHI-PROJECT-24229003
  • [Journal Article] Aggregatibacter actinomycetemcomitans Invasion Induces Interleukin-1β Production Through Reactive Oxygen Species and Cathepsin B2015

    • Author(s)
      Okinaga T, Ariyoshi W, Nishihara T.
    • Journal Title

      Journal of interferon & cytokine research

      Volume: 0 Issue: 6 Pages: 0-0

    • DOI

      10.1089/jir.2014.0127

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Journal Article] Effects of proinflammatory cytokines on odontoblastic differentiation and mineralization of odontoblast-like cells2015

    • Author(s)
      Nakagawa A, Okinaga T, Ariyoshi W, Morotomo T, Kitamura C, Nishihara T
    • Journal Title

      Inflammation and Regeneration

      Volume: 35 (4) Pages: 210-217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15696
  • [Journal Article] Essential role of JAK/STAT pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter actinomycetemcomitans.2013

    • Author(s)
      Okinaga T, Ariyoshi W, Akifusa S, Nishihara T.
    • Journal Title

      Med Microbiol Immunol.

      Volume: 202 Issue: 2 Pages: 167-174

    • DOI

      10.1007/s00430-012-0282-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390389, KAKENHI-PROJECT-23390482, KAKENHI-PROJECT-23792149, KAKENHI-PROJECT-24593000, KAKENHI-PROJECT-24659841, KAKENHI-PROJECT-24659937
  • [Journal Article] A. actinomycetemcomitans LPS Enhances Foam Cell Formation Induced by LDL2013

    • Author(s)
      Morishita M, Ariyoshi W, Okinaga T, Usui M, Nakashima K, Nishihara T
    • Journal Title

      J Dent Res

      Volume: 92 Pages: 241-6

    • Data Source
      KAKENHI-PROJECT-23792149
  • [Journal Article] Mechanisms involved in suppression of ADAMTS4 expression in synoviocytes by high molecular weight hyaluronic acid2013

    • Author(s)
      Kataoka Y, Ariyoshi W, Okinaga T, Kaneuji T,Mitsugi S, Takahashi T, Nishihara T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 432 Issue: 4 Pages: 580-585

    • DOI

      10.1016/j.bbrc.2013.02.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390389, KAKENHI-PROJECT-24593000, KAKENHI-PROJECT-24659841, KAKENHI-PROJECT-23592995
  • [Journal Article] Mechanisms of G1 cell cycle arrest and apoptosis in myeloma cells induced by hybrid-compound histone deacetylase inhibitor.2013

    • Author(s)
      Fujii S, Okinaga T, Ariyoshi W, Takahashi O, Iwanaga K, Nishino N, Tominaga K, Nishihara T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 434 (3) Pages: 413-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Journal Article] Mechanisms of G1 cell cycle arrest and apoptosis in myeloma cells induced by hybrid-compound histone deacetylase inhibitor2013

    • Author(s)
      Fujii, S., Okinaga, T., Ariyoshi, W., Takahashi, O., Iwanaga, K., Nishino, N., Tominaga, K., Nishihara, T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 434 Issue: 3 Pages: 413-20

    • DOI

      10.1016/j.bbrc.2013.03.043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390389, KAKENHI-PROJECT-23792377, KAKENHI-PROJECT-24593000, KAKENHI-PROJECT-24659841
  • [Journal Article] High Molecular Weights Hyaluronic Acid Regulates Osteoclast Formation by Inhibiting Receptor Activator of NF-κB Ligand through Rho Kinase2013

    • Author(s)
      Ariyoshi W, Okinaga T, Knudson C, Knudson W, Nishihara T
    • Journal Title

      Osteoarthritis Cartilage

      Volume: 22 (1) Issue: 1 Pages: 111-120

    • DOI

      10.1016/j.joca.2013.10.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24593000, KAKENHI-PROJECT-24659841
  • [Journal Article] Essential role of JAK/STAT pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter actinomycetemcomitans2013

    • Author(s)
      Okinaga T, Ariyoshi W, Akifusa S, Nishihara T
    • Journal Title

      Med Microbiol Immunol

      Volume: 202 Pages: 167-74

    • Data Source
      KAKENHI-PROJECT-23792149
  • [Journal Article] A. actinomycetemcomitans LPS Enhances Foam Cell Formation Induced by LDL2013

    • Author(s)
      Morishita M, Ariyoshi W, Okinaga T, Usui M, Nakashima K, Nishihara T (Morishita)
    • Journal Title

      Journal of Dental Research

      Volume: 92 Issue: 3 Pages: 241-246

    • DOI

      10.1177/0022034512473309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792149, KAKENHI-PROJECT-24593000, KAKENHI-PROJECT-24593129, KAKENHI-PROJECT-24659841
  • [Journal Article] 歯周炎におけるマクロファージの機能の多様性2012

    • Author(s)
      沖永敏則,西原達次
    • Journal Title

      第2回マクロファージにおける炎症応答でのインフラマソームの役割日本歯科評論

      Volume: 第841号 Pages: 153-155

    • Data Source
      KAKENHI-PROJECT-24659841
  • [Journal Article] Mechanisms involved in inhibition of chondrogenesis by activin-A2012

    • Author(s)
      Mitsugi S, Ariyoshi W, Okinaga T, Kaneuji T, Kataoka Y, Takahashi T, Nishihara T
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 420 (2) Issue: 2 Pages: 380-384

    • DOI

      10.1016/j.bbrc.2012.03.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24593000, KAKENHI-PROJECT-24659841, KAKENHI-PROJECT-23592995
  • [Presentation] Transposon insersion mutagenesis in Rothia dentocariosa.2023

    • Author(s)
      B. Liu, C. Mashimo, T. Nambu, H. Maruyama, T. Okinaga.
    • Organizer
      101st General Session & Exhibition of the International Association Dental Research
    • Data Source
      KAKENHI-PROJECT-19K10456
  • [Presentation] Rothia属細菌を利用した新規遺伝子改変技術の開発2023

    • Author(s)
      劉柏昂, 真下千穂, 南部隆之, 円山由郷, 沖永敏則
    • Organizer
      第65回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10456
  • [Presentation] Considering the Balance of Oral Bacterial Flora ~Focusing on Fusobacterium spices involved in systemic disease~2023

    • Author(s)
      Okinaga T
    • Organizer
      2nd Asia-Pacific Dental High-tech Expo
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K09954
  • [Presentation] F. nucleatum が誘導する上皮間葉転換に対するレスベラトロール の影響2023

    • Author(s)
      Jie Min,沖永敏則,真下千穂,南部隆之,円山由郷
    • Organizer
      第96回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-22K09954
  • [Presentation] ハワイ州産プロポリスの口腔細菌へ与える影響について2022

    • Author(s)
      康文岩、円山由郷、川野亜希、沖永敏則
    • Organizer
      第573回大阪歯科学会例会
    • Data Source
      KAKENHI-PROJECT-22K09954
  • [Presentation] ブラジル連邦共和国バイーア州産プロポリスの口腔細菌への影響2022

    • Author(s)
      瀧川博樹、真下千穂、南部隆之、円山由郷、沖永敏則
    • Organizer
      第64回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K10456
  • [Presentation] Interdental Plaque Microbial Community Changes under In Vitro Violet LED Irradiation2021

    • Author(s)
      Wang Dan、Nambu Takayuki、Tanimoto Hiroaki、Iwata Naohiro、Yoshikawa Kazushi、Okinaga Toshinori、Yamamoto Kazuyo
    • Organizer
      第74回日本細菌学会関西支部総会
    • Data Source
      KAKENHI-PROJECT-19K10473
  • [Presentation] 高齢者舌苔細菌叢に与えるサルコペニアの影響2020

    • Author(s)
      並河大裕,真砂彩子,南部隆之,小渕隆一郎,奥野健太郎,Kang Wenyan,Zhang Lei,沖永敏則,高橋一也
    • Organizer
      第31回日本老年歯科医学会
    • Data Source
      KAKENHI-PROJECT-19K10473
  • [Presentation] プロポリスが示す細菌種特異的な増殖抑制効果2020

    • Author(s)
      並河大裕,円山由郷,真砂彩子,真下千穂,南部隆之,沖永敏則,高橋一也
    • Organizer
      第73回日本細菌学会関西支部総会
    • Data Source
      KAKENHI-PROJECT-19K10473
  • [Presentation] 細菌誘導のマクロファージ細胞応答におけるオメガ3系脂肪酸の影響2019

    • Author(s)
      川野亜希、有吉 渉、沖永敏則
    • Organizer
      第40回日本炎症・再生医学会2019
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] Role of omega-3 fatty acid on inflammasome activity in Aggregatibacter actinomycetemcomitans-invaded macrophages2019

    • Author(s)
      Aki Kawano, Wataru Ariyoshi, Toshinori Okinaga
    • Organizer
      Asia-Pacific Conference in Fukuoka 2019- International Symposium on Oral Education and Research in Kitakyushu
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] インフラマソーム活性に対するオメガ3 系脂肪酸の影響2019

    • Author(s)
      川野亜希、有吉 渉、吉岡香絵、山崎亮太、沖永敏則
    • Organizer
      第61回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] 単球マクロファージ系細胞の分化に対する多価不飽和脂肪酸の影響2018

    • Author(s)
      川野亜希、沖永敏則、有吉 渉、引地尚子、西原達次
    • Organizer
      第39回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] Effect of β-glucan and dectin-1 binding on periodontopathic bacteria-invaded macrophages2018

    • Author(s)
      Maki Inoue, Toshinori Okinaga, Wataru Ariyoshi, Masaki Morishita, Michihiko Usui, Keisuke Nakashima, Tatsuji Nishihara
    • Organizer
      Asia-Pacific Conference in Fukuoka 2018- International Symposium on Oral Education and Research in Kitakyushu
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] マクロファージ分化に及ぼすドコサヘキサエン酸の影響2018

    • Author(s)
      川野亜希、沖永敏則、有吉 渉、引地尚子、西原達次
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] 血管内皮細胞におけるIL-17Aの生物学的機能の解明について2018

    • Author(s)
      塩次將平、有吉 渉、沖永敏則、吉岡 泉、西原達次
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] βグルカン添加による歯周病細菌侵入マクロファージに見られる細胞死抑制効果について2018

    • Author(s)
      井上真紀、沖永敏則、有吉 渉、守下昌輝、臼井通彦、西原達次
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] 歯周病細菌誘導のインフラマソーム活性におけるオメガ3脂肪酸の役割2018

    • Author(s)
      沖永敏則、有吉 渉、Chuencheewit Thongsiri、西原達次
    • Organizer
      第60回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] Effect of polyunsaturated fatty acids on macrophage polarization2018

    • Author(s)
      Aki Kawano, Toshinori Okinaga, Wataru Ariyoshi, Hisako Hikiji, Tatsuji Nishihara
    • Organizer
      Effect of polyunsaturated fatty acids on macrophage polarization Asia-Pacific Conference in Fukuoka 2018- International Symposium on Oral Education and Research in Kitakyushu
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] 血管内皮細胞におけるInterleukin-17A(IL-17A)の生物学的機能の解明について2018

    • Author(s)
      塩次將平、有吉 渉、沖永敏則、吉岡 泉、西原達次
    • Organizer
      第78回九州歯科学会総会学術大会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] 血管内皮細胞におけるInterleukin-17A(IL-17A)の生物学的機能の解明について2018

    • Author(s)
      塩次將平、有吉 渉、沖永敏則、西原達次
    • Organizer
      第39回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-18K09556
  • [Presentation] ドコサヘキサエン酸は歯周病細菌誘導インフラマソーム活性を制御する2017

    • Author(s)
      沖永敏則, 有吉渉, 西原達次
    • Organizer
      第70回日本細菌学会九州支部総会
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] The role of Docosahexaenoic acid on inflammasome activity induced by A. actinomycetemcomitans invasion macrophages2017

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      日本細菌学会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-19
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] The role of Docosahexaenoic acid on inflammasome activity induced by A. actinomycetemcomitans invasion macrophages2017

    • Author(s)
      沖永敏則, 有吉渉, 西原達次
    • Organizer
      第90回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] Omega-3 fatty acids regulate inflammasome activity and pyroptosis induced by A. actinomycetemcomitans invasion in macrophages2017

    • Author(s)
      Okinaga T, Ariyoshi W, Nishihara T
    • Organizer
      15th International Congress of Bacteriology and Applied Microbiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] オメガ3脂肪酸は歯周病細菌が誘導するインフラマソーム活性を抑制する2017

    • Author(s)
      沖永敏則, 有吉渉, 西原達次
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] クロファージ分化におけるω-3系脂肪酸の役割2016

    • Author(s)
      川野亜希、沖永敏則、引地尚子、有吉渉、西原達次
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      北海道
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] オメガ3脂肪酸は歯周病細菌侵入マクロファージが誘導するインフラマソーム活性を抑制する2016

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      北海道
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] A. actinomycetemcomitansが誘導するサイトカイン産生に対するオメガ3脂肪酸の影響2016

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      日本細菌学会九州支部総会
    • Place of Presentation
      宮崎
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] Docosahexaenoic acid downregulates inflammasome activity and endocytosis in A. actinomycetemcomitans-invaded macrophages2016

    • Author(s)
      沖永敏則, 有吉渉, 西原達次
    • Organizer
      日本細菌学会
    • Place of Presentation
      大阪
    • Year and Date
      2016-03-23
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] ATDC5細胞の軟骨分化におけるリゾリン脂質アシル転移酵素の働き2016

    • Author(s)
      田部士郎、引地尚子、有吉 渉、沖永敏則、西原達次
    • Organizer
      第58回歯科基礎医学会学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2016-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15696
  • [Presentation] Lysophosphatidylethanolamine acyltransferase 1 regulates morphology and function of P19C6 cell-derived neurons2016

    • Author(s)
      Tabe S, Hikiji H, Ariyoshi W, Okinaga T, Nishihara T
    • Organizer
      IADR/APR General Session & Exhibition
    • Place of Presentation
      Seoul, Republic of Korea
    • Year and Date
      2016-06-22
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15696
  • [Presentation] オメガ3脂肪酸は歯周病細菌が誘導するインフラマソーム活性を抑制する2015

    • Author(s)
      沖永敏則, 有吉渉, 西原達次
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K11083
  • [Presentation] The anti-inflammatory effect of a newly identified adipokine apelin on macrophage.2014

    • Author(s)
      SHIGEYUKI OBARA, SUMIO AKIFUSA, MICHIHIKO USUI, WATARU ARIYOSHI, TOSHINORI OKINAGA, TATSUJI NISHIHARA, KEISUKE NAKASHIMA
    • Organizer
      Asia-Pacific Conference in Fukuoka 2014- International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Dectin-1 activation inhibits an inflammatory response to bacterial infection2014

    • Author(s)
      沖永敏則, 有吉渉, 西原達次
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 細菌誘導インフラマソーム活性に対するβ-1,3 glucanの制御2014

    • Author(s)
      沖永敏則、有吉渉、臼井通彦、西原達次
    • Organizer
      日本炎症・再生医学会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Presentation] Pyroptosis and NLRP3 inflammasome activation in periodontopathic bacteria infected-macrophages are mediated by reactive oxygen species and cathepsin B.2014

    • Author(s)
      TOSHINORI OKINAGA, WATARU ARIYIOSHI, TATSUJI NISHIHARA
    • Organizer
      Asia-Pacific Conference in Fukuoka 2014- International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Dectin-1 activation inhibits an inflammatory response to bacterial infection2014

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      日本細菌学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Presentation] 歯周病細菌感染マクロファージにおけるインフラマソーム活性2013

    • Author(s)
      沖永敏則,有吉渉,西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 西原達次 歯周病原性細菌マクロファージのピロトーシス誘導におけるインフラマソームの役割2013

    • Author(s)
      沖永敏則、有吉渉
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 歯周病細菌感染マクロファージにおけるインフラマソーム活性2013

    • Author(s)
      沖永敏則、有吉 渉、西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 新規アディポカインapelinによる炎症反応に対する影響2013

    • Author(s)
      小原成将, 秋房住郎, 臼井通彦, 笠井宏記, 有吉渉, 沖永敏則, 西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Inflammasome activation via periodontopathic bacterial infection in macrophage2013

    • Author(s)
      T. Okinaga, W. Ariyoshi, M. Usui and T. Nishihara
    • Organizer
      IADR-APR
    • Place of Presentation
      タイ バンコク
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Presentation] Curdlan regulates osteoclastic differenti- ation and function2013

    • Author(s)
      Yamazaki T, Ariyoshi W, Okinaga T, Hosokawa R, Nishihara T
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] The involvement of inflammasome in mouse macrophage infected with Aggregatibacter actinomycetem- comitans2013

    • Author(s)
      Okinaga T, Ariyoshi W, Nishihara T
    • Organizer
      International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Year and Date
      2013-01-26
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 歯周病細菌感染マクロファージにおけるインフラマソーム活性2013

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Presentation] High-molecular-weight hyaluronic acid down-regulates the expression of ADAMTS4 in synoviocytes2013

    • Author(s)
      Kataoka Y, Ariyoshi W, Okinaga T, Kaneuji T, Takahashi T, Nishihara T
    • Organizer
      IADR
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Classification of periodontal disease patients by FT-IR.2013

    • Author(s)
      SATOSHI FUJII, KEISUKE FUKUDA、SHINOBU SATO, TOSHINORI OKINAGA, WATARU ARIYOSHI, KEISUKE NAKASHIMA, TATSUJI NISHIHARA, SHIGEORI TAKENAKA
    • Organizer
      Asia-Pacific Conference in Fukuoka 2013- International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Effect of Dectin-1 signaling on osteoclasto- genesis2013

    • Author(s)
      Yamasaki T, Ariyoshi W, Okinaga T, Hosokawa R, Nishihara T
    • Organizer
      IADR
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 歯周病原性細菌感染マクロファージのピロトーシス誘導におけるインフラマソームの役割2013

    • Author(s)
      沖永敏則、有吉 渉、西原達次
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Inflammasome activation via periodontopathic bacterial infection in macrophage.2013

    • Author(s)
      TOSHINORI OKINAGA, WATARU ARIYIOSHI, TATSUJI NISHIHARA
    • Organizer
      2nd Meeting of the International Association for Dental Research – Asia Pacific Region
    • Place of Presentation
      Bangkok, Thailand
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] High molecular weights Hyaluronic Acid Regulates Osteoclastogenesis.2013

    • Author(s)
      WATARU ARIYOSHI, TOSHINORI OKINAGA, CHERYL B KNUDSON, WARREN KNUDSON, TATSUJI NISHIHARA
    • Organizer
      Hyaluronan 2013
    • Place of Presentation
      Oklahoma, United States
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 新規アディポカインapelinによる炎応答に対する影響2013

    • Author(s)
      小原成将、秋房住郎、臼井通彦、笠井宏記、沖永敏則、有吉 渉、西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] アメロブラスチンは口腔上皮細胞の細胞増殖を抑制する2013

    • Author(s)
      西藤法子, 有吉渉, 沖永敏則, 鷲尾絢子, 北村知昭, 西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Curdlan regulates osteoclastic differentiation and function.2013

    • Author(s)
      TORU YAMASAKI, WATARU ARIYOSHI, TOSHINORI OKINAGA, RYUJI HOSOKAWA, TATSUJI NISHIHARA.
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] アメロブラスチンは口腔上皮細胞増殖を抑制する2013

    • Author(s)
      西藤法子、有吉 渉、沖永敏則、鷲尾絢子、北村知昭、西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 新規アディポカインapelinの免疫機能に対する影響について2013

    • Author(s)
      小原成将, 秋房住郎, 臼井通彦, 笠井宏記, 有吉渉, 沖永敏則, 西原達次, 中島啓介
    • Organizer
      第74回九州歯科学会総会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Streptococcus sanguinisはマクロファージの泡沫化と細胞死を誘導する2013

    • Author(s)
      岡橋暢夫,沖永敏則,桜井敦朗,寺尾豊,中田匡宣,川端重忠,西原達次
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] The involvement of inflammasome in mouse macrophage infected with Aggregatibacter actinomycetemcomitans.2013

    • Author(s)
      TOSHINORI OKINAGA, WATARU ARIYIOSHI, TATSUJI NISHIHARA
    • Organizer
      Asia-Pacific Conference in Fukuoka 2013- International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] PC12細胞の神経細胞分化に対する各種セメントの影響2013

    • Author(s)
      中川愛加,沖永敏則,鷲尾絢子,寺下正道,北村知昭,西原達次
    • Organizer
      第74回九州歯科学会総会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] New detection system for the adhesion of oral bacteria on macrophages in vitro2013

    • Author(s)
      Morishita M, Okinaga T, Ariyoshi W, Nakashima K, Nishihara T
    • Organizer
      International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Year and Date
      2013-01-26
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 歯周病細菌の生育を抑制・阻害する緑膿菌分泌物の作用機構の追及2013

    • Author(s)
      常岡祐介,前田憲成,沖永敏則,西原達次
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 新規アディポカインapelinの免疫機能に対する影響について2013

    • Author(s)
      小原成将、秋房住郎、臼井通彦、笠井宏記、有吉 渉、沖永敏則、西原達次、中島啓介
    • Organizer
      第73回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] High-Molecular-Weight Hyaluronic Acid down-regulates the expression of ADAMTS4 in synoviocytes.2013

    • Author(s)
      YOSHIHIRO KATAOKA, WATARU ARIYOSHI, TOSHINORI OKINAGA, TAKESHI KANEUJI, TETSU TAKAHASHI, TATSUJI NISHIHARA.
    • Organizer
      91th General Session & Exhibition of the IADR
    • Place of Presentation
      Seattle, United States
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Role of Ameloblastin in Epithelial Cells Proliferation.2013

    • Author(s)
      NORIKO SAITOU, SACHIKO KURAMITSU, AYAKO WASHIO, WATARU ARIYOSHI, TOSHINORI OKINAGA, CHIAKI KITAMURA, KAZUNORI YAMAGUCHI, TATSUJI NISHIHARA.
    • Organizer
      91th General Session & Exhibition of the IADR
    • Place of Presentation
      Seattle, United States
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Inhibitory effect of hyaluronic acid on osteoclastogenesis via Rho kinase2013

    • Author(s)
      Ariyoshi W, Okinaga T, Nishihara T
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Effect of Dectin-1 signaling on osteoclastogenesis.2013

    • Author(s)
      TORU YAMASAKI, WATARU ARIYOSHI, TOSHINORI OKINAGA, RYUJI HOSOKAWA, TATSUJI NISHIHARA.
    • Organizer
      91th General Session & Exhibition of the IADR
    • Place of Presentation
      Seattle, United States
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] New detection system the adhesion of oral bacteria on macrophages in vitro.2013

    • Author(s)
      MASAKI MORISHITA, TOSHINORI OKINAGA, WATARU ARIYOSHI, KEISUKE NAKASHIMA, TATSUJI NISHIHARA
    • Organizer
      Asia-Pacific Conference in Fukuoka 2013- International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] アメロブラスチン発現による上皮細胞増殖への影響について2013

    • Author(s)
      西藤法子、蔵満幸子、有吉 渉、沖永敏則、北村知昭、山口和憲、西原達次
    • Organizer
      第73回九州歯科学会総会
    • Place of Presentation
      北九州市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] The effect of HDAC inhibitor on mouse myeloma cells.2013

    • Author(s)
      SEIKO FUJII, TOSHINORI OKINAGA, WATARU ARIYOSHI WATARU, OSAMU TAKAHASHI, KENJIRO IWANAGA, MANABU HABU, KAZUHIRO TOMINAGA, TATSUJI NISHIHARA
    • Organizer
      91th General Session & Exhibition of the IADR
    • Place of Presentation
      Seattle, United States
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 歯周病原性細菌マクロファージのピロトーシス誘導におけるインフラマソームの役割2013

    • Author(s)
      沖永敏則, 有吉渉, 西原達次
    • Organizer
      第86回日本細菌学会総会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Inhibitory Effect of Hyaluronic Acid on Osteoclastogenesis via Rho Kinase.2013

    • Author(s)
      WATARU ARIYOSHI, TOSHINORI OKINAGA, TATSUJI NISHIHARA
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] High molecular weight hyaluronan down-regulates the expression of ADAMTS4 via p38 MAPK signaling pathway in human synoviacytes2013

    • Author(s)
      Kataoka Y, Ariyoshi W, Okinaga T, Nishihara T
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] アメロブラスチン発現による上皮細胞増殖への影響について2013

    • Author(s)
      西藤法子, 蔵満幸子, 有吉渉, 沖永敏則, 北村知昭, 山口和憲, 西原達次
    • Organizer
      第74回九州歯科学会総会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] High molecular weight hyaluronan down-regulates the expression of ADAMTS4 via p38 MAPK signaling pathway in human synoviocytes.2013

    • Author(s)
      YOSHIHIRO KATAOKA, WATARU ARIYOSHI, TOSHINORI OKINAGA, TATSUJI NISHIHARA.
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and The Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Inactivation of periodontal pathogens by Pseudomonas aeruginosa.2013

    • Author(s)
      YUSUKE TSUNEOKA, TOSHINARI MAEDA, TOSHINORI OKINAGA, WATARU ARIYOSHI, TATSUJI NISHIHARA
    • Organizer
      Asia-Pacific Conference in Fukuoka 2013- International Symposium on Oral Education and Research in Kitakyushu
    • Place of Presentation
      Kitakyushu, Japan
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Curdlan-dectin-1を介した新たな破骨細胞分化の制御機構2013

    • Author(s)
      山﨑徹,有吉渉,沖永敏則,細川隆司,西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] The effect of HDAC inhibitor on mouse myeloma cells2013

    • Author(s)
      Fujii S, Okinaga T, Ariyoshi W, Takahashi O, Iwanaga K, Habu M, Tominaga K, Nishihara T
    • Organizer
      IADR
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] High molecular weights hyaluronic acid regulates osteoclastogenesis2013

    • Author(s)
      Ariyoshi W, Okinaga T, Knudson CB, Knudson W, Nishihara T
    • Organizer
      Hyaluronan 2013
    • Place of Presentation
      Oklahoma, USA
    • Year and Date
      2013-06-07
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Curdlan-dectin-1を介した新たな破骨細胞分化の制御機構2013

    • Author(s)
      山﨑 徹、有吉 渉、沖永敏則、細川隆司、西原達次
    • Organizer
      第55回歯科基礎医学会学術大会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Inflammasome activation via periodontopathic bacterial infection in macrophage2013

    • Author(s)
      Okinaga T, Ariyoshi W, Usui M, Nishihara T
    • Organizer
      2^<nd> meeting of IADR-Asia Pathific Region
    • Place of Presentation
      Bangkok, Thailand
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] The involvement of inflammasome in mouse macrophage infected with Aggregatibacter actinomycetemcomitans Asia-Pacific Conference in Fukuoka 2013 International Symposium on Oral Education and Research in Kitakyushu Kyushu Dental University2013

    • Author(s)
      T Okinaga, W Ariyoshi, T Nishihara
    • Organizer
      Asia-Pacific Conference in Fukuoka 2013 International Symposium on Oral Education and Research in Kitakyushu Kyushu Dental University
    • Place of Presentation
      Kitakyushu, Japan 26th
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 破骨細胞支持能に対する高分子ヒアルロン酸の抑制効果について2012

    • Author(s)
      有吉渉,沖永敏則,西原達次
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      群山
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 西原達次Streptococcus sanguinis のマクロファージへの付着に関わる分子について2012

    • Author(s)
      守下昌輝、沖永敏則、有吉渉
    • Organizer
      第65回日本細菌学会九州支部総会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] アメロブラスチンの上皮細胞増殖への影響について2012

    • Author(s)
      西藤法子、蔵満幸子、有吉 渉、沖永敏則、北村知昭、山口和憲、西原達次
    • Organizer
      第72回九州歯科学会学術大会
    • Place of Presentation
      北九州市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 歯周病原性細菌はマクロファージにおけるpyroptosisを誘導する2012

    • Author(s)
      有吉 渉、沖永敏則、西原達次
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      郡山市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 歯周病原性細菌はマクロファージにおけるpyroptosis を誘導する2012

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      第54回歯科基礎医学会
    • Place of Presentation
      郡山
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 歯周病原性細菌はマクロファージにおけるpyroptosisを誘導する2012

    • Author(s)
      沖永敏則,有吉渉,西原達次
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      群山
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 滑膜細胞における高分子量ヒアルロン酸によるADAMTS4産生抑制機構2012

    • Author(s)
      片岡良浩、有吉 渉、沖永敏則、金氏 毅、高橋 哲、西原達次
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      郡山市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] マクロファージ貪食機能ににおけるデクチンの役割について2012

    • Author(s)
      井上真紀,藤井誠子,片岡良浩,守下昌輝,沖永敏則,有吉渉,西原達次
    • Organizer
      第72回九州歯科学会総会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] マクロファージ貪食機能におけるデクチンの役割について2012

    • Author(s)
      井上真紀、藤井誠子、片岡良浩、守下昌輝、沖永敏則、有吉 渉、西原達次
    • Organizer
      第72回九州歯科学会学術大会
    • Place of Presentation
      北九州市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 破骨細胞分化におけるDectin-1の作用について2012

    • Author(s)
      山﨑 徹、有吉 渉、沖永敏則、細川隆司、西原達次
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      郡山市
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] A simple approach to test periodontal disease frpm saliva using fourier transporform infrared spectroscopy2012

    • Author(s)
      Fujii S, Fukuda K, Okinaga T, Ariyoshi W, Nakashima K, Nishihara T, Sarai A, Sato S, Takenaka S
    • Organizer
      The fifth Japan-Korea Joint Symposium on Bio-microsensing Technology
    • Place of Presentation
      Kitakyushu, Japan
    • Year and Date
      2012-10-26
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] 破骨細胞文化におけるDectin-1の作用について2012

    • Author(s)
      山崎徹,有吉渉,沖永敏則,細川隆司,西原達次
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      群山
    • Data Source
      KAKENHI-PROJECT-24659841
  • [Presentation] Effects of Lipopolysaccharide and lipoproteinon the plaque formation of murine macrophages2011

    • Author(s)
      Morishita M., Nakashima K., Okinaga T., Ariyoshi W., Nishihara T
    • Organizer
      International Union ofMicrobiological Societies 2011 Congress
    • Place of Presentation
      Sapporo, JAPAN
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 西原達次歯周病細菌感染アポトーシス誘導モデルにおける SOCS の調節メカニズム2011

    • Author(s)
      沖永敏則、有吉渉、秋房住郎
    • Organizer
      第53回歯科基礎医学会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 西原達次 LPS で刺激した RAW264.7細胞の凝集形成におけるリポタンパク質の影響について2011

    • Author(s)
      守下昌輝、中島啓介、沖永敏則、有吉渉
    • Organizer
      第53回歯科基礎医学会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 歯周病細菌が誘導する炎症性サイトカイン産生に対するβ-1,3 glucanの制御

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      日本細菌学会 九州支部総会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-09-05 – 2014-09-06
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Presentation] Effects of Lipopolysaccharide and lipoprotein on the plaque formation of murine macrophages.

    • Author(s)
      11)Morishita M., Nakashima K., Okinaga T., Ariyoshi W., Nishihara T.
    • Organizer
      International Union of Microbiological Societies
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] The involvement of inflammasome in mouse macrophage infected with Aggregatibacter actinomycetemcomitans

    • Author(s)
      Toshinori Okinaga, Wataru Ariyoshi, Tatsuji Nishihara
    • Organizer
      Asia-Pacific Conference in Fukuoka 2013 International Symposium on Oral Education and Research
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 歯周病細菌感染アポトーシス誘導モデルにおけるSOCSの調節メカニズム

    • Author(s)
      沖永敏則、有吉渉、秋房住郎、西原達次
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] Streptococcus sanguinisのマクロファージへの付着に関わる分子について

    • Author(s)
      守下昌輝、沖永敏則、有吉渉、西原達次 (沖永敏則)
    • Organizer
      日本細菌学会 九州支部総会
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] β-1,3 glucanのインフラマソーム活性制御メカニズムについて

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      歯科基礎医学会学術大会
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Presentation] 細菌誘導インフラマソーム活性に対するβ -1,3 glucan の制御

    • Author(s)
      沖永敏則,有吉渉,臼井通彦,西原達次
    • Organizer
      日本炎症再生医学会
    • Place of Presentation
      沖縄
    • Year and Date
      2014-07-01 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-25861775
  • [Presentation] LPSで刺激したRAW264.7細胞の凝集形成におけるリポタンパク質の影響について

    • Author(s)
      守下昌輝、中島啓介、沖永敏則、有吉渉、西原達次
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      岐阜
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 歯周病原性細菌はマクロファージにおけるpyroptosisを誘導する

    • Author(s)
      沖永敏則、有吉渉、西原達次 (沖永敏則)
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      郡山
    • Data Source
      KAKENHI-PROJECT-23792149
  • [Presentation] 歯周病原性細菌マクロファージのピロトーシス誘導におけるインフラマソームの役割

    • Author(s)
      沖永敏則、有吉渉、西原達次
    • Organizer
      日本細菌学会総会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23792149
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