Imae Rieko 今江理恵子

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IMAE Rieko 今江理恵子

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Researcher Number	60584000
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 准主任研究員
Affiliation (based on the past Project Information) *help	2016 – 2023: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2014: 東京大学, 薬学研究科(研究院), 助教 2011 – 2013: 東京女子医科大学, 医学部, 助教 2010: 東京大学, 大学院・薬学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Functional biochemistry
Keywords	Principal Investigator CDP-グリセロール / 癌 / グリセロール-3-リン酸含有糖鎖 / CDP-エタノールアミン / 膵癌 / グリセロールリン酸 / α-ジストログリカン / 糖鎖 / PCYT2 / 細胞・組織 … More / 脂質 / トリグリセリド代謝 / 脂肪肝 / アラキドン酸 / ホスファチジルイノシトール / メンブレントラフィック / RNAi / ホスホイノシチド / 非対称分裂 Less

グリセロール-3-リン酸含有糖鎖の合成制御機構および癌における役割の解明Principal Investigator
- Principal Investigator
  
  今江理恵子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Investigation of the biological significance of glycerol phosphate-containing glycanPrincipal Investigator
- Principal Investigator
  
  Imae Rieko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
The biological significance of characteristic fatty acid composition of phosphatidylinositolPrincipal Investigator
- Principal Investigator
  
  Imae Rieko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Analysis of the molecular mechanisms involved in the intercellular transfer of double-stranded RNAPrincipal Investigator
- Principal Investigator
  
  IMAE Rieko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
  Tokyo Women's Medical University
Biological significance of the unique fatty acid composition of phosphatidylinositol in the asymmetric division of stem cells.Principal Investigator
- Principal Investigator
  
  IMAE Rieko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Women's Medical University
  The University of Tokyo

[Book] 生体の科学　特集　脂質ワールド2016
- Author(s)
  今江　理恵子, 河野　望, 新井　洋由
- Total Pages
  4
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-16K20996
[Journal Article] Endogenous reductase activities for the generation of ribitol-phosphate, a CDP-ribitol precursor, in mammals2023
- Author(s)
  Hoshino Shunsuke、Manya Hiroshi、Imae Rieko、Kobayashi Kazuhiro、Kanagawa Motoi、Endo Tamao
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 175 Issue: 4 Pages: 418-425
- DOI
  10.1093/jb/mvad115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06110, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-21H02685, KAKENHI-PROJECT-23K24244, KAKENHI-PROJECT-23K27328
[Journal Article] An endomembrane zinc transporter negatively regulates systemic RNAi in Caenorhabditis elegans2023
- Author(s)
  Dejima Katsufumi、Imae Rieko、Suehiro Yuji、Yoshida Keita、Mitani Shohei
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 6 Pages: 106930-106930
- DOI
  10.1016/j.isci.2023.106930
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06561, KAKENHI-PROJECT-23K06110, KAKENHI-PROJECT-20H03422
[Journal Article] Chemical and Chemo-Enzymatic Syntheses of Glycans Containing Ribitol Phosphate Scaffolding of Matriglycan2022
- Author(s)
  Tamura Jun-ichi、Tamura Takahiro、Hoshino Shunsuke、Imae Rieko、Kato Ryuichi、Yokono Mizuki、Nagase Mao、Ohno Shiho、Manabe Noriyoshi、Yamaguchi Yoshiki、Manya Hiroshi、Endo Tamao
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 17 Issue: 6 Pages: 1513-1523
- DOI
  10.1021/acschembio.2c00181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06562, KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-19H05648
[Journal Article] CDP-ribitol prodrug treatment ameliorates ISPD-deficient muscular dystrophy mouse model2022
- Author(s)
  Tokuoka Hideki、Imae Rieko、Nakashima Hitomi、Manya Hiroshi、Masuda Chiaki、Hoshino Shunsuke、Kobayashi Kazuhiro、Lefeber Dirk J.、Matsumoto Riki、Okada Takashi、Endo Tamao、Kanagawa Motoi、Toda Tatsushi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1847-1847
- DOI
  10.1038/s41467-022-29473-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-22K19509, KAKENHI-PROJECT-20H00526, KAKENHI-PROJECT-21H02685, KAKENHI-PROJECT-19K07058, KAKENHI-WRAPUP-22H04899, KAKENHI-PROJECT-23K20328, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-23K24244
[Journal Article] PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan2021
- Author(s)
  Imae Rieko、Manya Hiroshi、Tsumoto Hiroki、Miura Yuri、Endo Tamao
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 170 Issue: 2 Pages: 183-194
- DOI
  10.1093/jb/mvab069
- NAID
  40022723391
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-19H05648
[Journal Article] The structure of POMGNT2 provides new insights into the mechanism to determine the functional <i>O</i> ‐mannosylation site on α‐dystroglycan2021
- Author(s)
  Imae Rieko、Kuwabara Naoyuki、Manya Hiroshi、Tanaka Tomohiro、Tsuyuguchi Masato、Mizuno Mamoru、Endo Tamao、Kato Ryuichi
- Journal Title
  
  Genes to Cells
  
  Volume: 26 Issue: 7 Pages: 485-494
- DOI
  10.1111/gtc.12853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-19H05648
[Journal Article] Biosynthetic mechanisms and biological significance of glycerol phosphate-containing glycan in mammals.2021
- Author(s)
  Rieko Imae, Hiroshi Manya, Tamao Endo
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 21 Pages: 6675-6675
- DOI
  10.3390/molecules26216675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-19H05648
[Journal Article] Biosynthetic Mechanisms of a Unique Ribitol Phosphate-containing Glycan by FKRP, a Ribitol Phosphate Transferase2020
- Author(s)
  Imae R, Kuwabara N, Manya H, Kato R, Endo T
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 32 Issue: 190 Pages: E195-E200
- DOI
  10.4052/tigg.2008.1E
- NAID
  130007942390
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2020-11-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-19H05648
[Journal Article] Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.2020
- Author(s)
  Kuwabara N, Imae R, Manya H, Tanaka T, Mizuno M, Tsumoto H, Kanagawa M, Kobayashi K, Toda T, Senda T, Endo T, Kato R.
- Journal Title
  
  Nat Commun.
  
  Volume: 11 Issue: 1 Pages: 303-303
- DOI
  10.1038/s41467-019-14220-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07058, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-19H05648, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-17H06264
[Journal Article] Biosynthetic mechanisms of ribitol phosphate-containing glycan by FKRP, a muscular dystrophy gene product2020
- Author(s)
  今江　理恵子、桑原　直之、萬谷　博、加藤　龍一、遠藤　玉夫
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 6 Pages: 811-816
- DOI
  10.14952/SEIKAGAKU.2020.920811
- NAID
  40022454265
- ISSN
  0037-1017
- Year and Date
  2020-12-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07058, KAKENHI-PROJECT-19H05648
[Journal Article] CDP-glycerol inhibits the synthesis of the functionalO-mannosyl glycan of α-dystroglycan2018
- Author(s)
  Imae Rieko、Manya Hiroshi、Tsumoto Hiroki、Osumi Kenji、Tanaka Tomohiro、Mizuno Mamoru、Kanagawa Motoi、Kobayashi Kazuhiro、Toda Tatsushi、Endo Tamao
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 31 Pages: 12186-12198
- DOI
  10.1074/jbc.ra118.003197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-17H01563, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987, KAKENHI-PROJECT-18H02616, KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16K20996
[Journal Article] Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5.2018
- Author(s)
  Nishihara, R., Kobayashi, K., Imae, R., Tsumoto, H., Manya, H., Mizuno, M., Kanagawa, M., Endo, T., and Toda, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 497 Issue: 4 Pages: 1025-1030
- DOI
  10.1016/j.bbrc.2018.02.162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08262, KAKENHI-PROJECT-16K20996, KAKENHI-PROJECT-26253057, KAKENHI-PROJECT-15H04352, KAKENHI-PLANNED-17H06421, KAKENHI-PROJECT-16H05353, KAKENHI-PROJECT-17H03987
[Journal Article] The Tumor Suppressor BCL7B Functions in the Wnt Signaling Pathway.2015
- Author(s)
  Uehara T, Kage-Nakadai E, Yoshina S, Imae R, Mitani S.
- Journal Title
  
  PLoS Genet.
  
  Volume: 11 Issue: 1 Pages: e1004921-e1004921
- DOI
  10.1371/journal.pgen.1004921
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390053, KAKENHI-PROJECT-24790092, KAKENHI-PROJECT-25870759, KAKENHI-PROJECT-26830049
[Journal Article] Methods for single/low-copy integration by ultraviolet and trimethylpsoralen treatment in Caenorhabditis elegans.2014
- Author(s)
  Kage-Nakadai E, Imae R, Yoshina S, Mitani S
- Journal Title
  
  Methods
  
  Volume: Mar 12 Issue: 3 Pages: 91-7
- DOI
  10.1016/j.ymeth.2014.02.036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790256, KAKENHI-PROJECT-24390053, KAKENHI-PROJECT-24790092, KAKENHI-PROJECT-25870759, KAKENHI-PROJECT-26830049
[Journal Article] A Conditional Knockout Toolkit for Caenorhabditis elegans Based on the Cre/loxP Recombination.2014
- Author(s)
  Kage-Nakadai E, Imae R, Suehiro Y, Yoshina S, Hori S, Mitani S.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 12 Pages: e114680-e114680
- DOI
  10.1371/journal.pone.0114680
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390053, KAKENHI-PROJECT-24790092, KAKENHI-PROJECT-25870759, KAKENHI-PROJECT-26830049
[Journal Article] ホスファチジルイノシトールの特徴的脂肪酸鎖の形成機構と生物学的意義2014
- Author(s)
  今江理恵子、新井洋由
- Journal Title
  
  医学のあゆみ
  
  Volume: 248 Pages: 1099-1104
- Data Source
  KAKENHI-PROJECT-24790092
[Journal Article] 線虫を用いたホスファチジルイノシトールの脂肪酸組成を規定する酵素群の同定2013
- Author(s)
  今江理恵子、三谷昌平、新井洋由
- Journal Title
  
  遺伝子医学MOOK
  
  Volume: 24
- Data Source
  KAKENHI-PROJECT-24790092
[Journal Article] Intracellular Phospholipase A_1 and Acyltransferase, Which Are Involved in Caenorhabditis elegans Stem Cell Divisions, Determine the sn-1 Fatty Acyl Chain of Phosphatidylinositol2010
- Author(s)
  Rieko Imae, Takao Inoue, Masako Kimura, Takahiro Kanamori, Naoko H. Tomioka, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: VOL.21 Pages: 3114-3124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22890032
[Presentation] 哺乳動物細胞におけるリビトールリン酸産生に関わる還元酵素の活性評価2023
- Author(s)
  星野駿介、今江理恵子、萬谷博、遠藤玉夫
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] ラミニン結合性O-マンノース型糖鎖の生合成制御機構の解析2023
- Author(s)
  今江　理恵子
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] Aging-associated changes in the amount of nucleotide sugars, the donor substrates for glycan biosynthesis, in mouse tissues.2023
- Author(s)
  Rieko Imae, Hiroshi Manya, Hiroki Tsumoto, Yuri Miura, Tamao Endo
- Organizer
  IAGG-AOR2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] Chemical and chemo-enzymatic synthesis of tandem ribitol phosphate scaffolding of matriglycan.2023
- Author(s)
  Jun-ichi Tamra, Takahiro Tamra, Shunsuke Hoshino, Rieko Imae, Ryuichi Kato, Mizuki Yokono, Mao Nagase, Shiho Ohno, Noriyoshi Manabe, Yoshiki Yamaguchi, Hiroshi Manya, Tamao Endo
- Organizer
  Eurocarb 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] 高異型度漿液性卵巣がんにおける糖転移酵素POMGnT1の腫瘍促進因子としての役割2023
- Author(s)
  竹岩俊彦, 今江理恵子, 萬谷博, 池田和博, 堀江公仁子, 井上聡
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] O-Man β1-4GlcNAc転移酵素POMGNT2の基質特異性の解析2023
- Author(s)
  星野　駿介、今江　理恵子、水野　真盛、蜷川　暁、萬谷　博、遠藤　玉夫
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] 糖鎖合成基質である糖ヌクレオチドの加齢マウス臓器における変化2023
- Author(s)
  今江　理恵子、萬谷　博、津元　裕樹、三浦　ゆり、遠藤　玉夫
- Organizer
  第46回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] 膵癌由来MIA PaCa-2細胞におけるα-ジストログリカン糖鎖伸長阻害因子CDP-グリセロールの機能解析2023
- Author(s)
  今江　理恵子、萬谷　博、濱　弘太郎、横山　和明、石渡　俊行、遠藤　玉夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] マウス臓器における糖ヌクレオチド含量の加齢変化2023
- Author(s)
  今江　理恵子、萬谷　博、津元　裕樹、三浦　ゆり、遠藤　玉夫
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 膵癌細胞におけるCDP-グリセロールによるα-ジストログリカン糖鎖伸長阻害の意義2023
- Author(s)
  今江　理恵子、萬谷　博、濱　弘太郎、横山　和明、石渡　俊行、遠藤　玉夫
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06110
[Presentation] CDP-エタノールアミン合成酵素PCYT2によるCDP-グリセロール生合成機構の発見およびα-ジストログリカンの機能制御2022
- Author(s)
  今江　理恵子、萬谷　博、津元　裕樹、三浦　ゆり、遠藤　玉夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 哺乳類におけるリビトールリン酸産生酵素の解析2022
- Author(s)
  星野　駿介、今江　理恵子、萬谷　博、遠藤　玉夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 加齢マウス臓器における糖ヌクレオチド量の変化2022
- Author(s)
  今江　理恵子、萬谷　博、津元　裕樹、三浦　ゆり、遠藤　玉夫
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] CHEMICAL AND CHEMO-ENZYMATIC SYNTHESES OF GLYCANS CONTAINING RIBITOL PHOSPHATE SCAFFOLDING OF MATRIGLYCAN.2022
- Author(s)
  Jun-ichi Tamura, Takahiro Tamura, Shunsuke Hoshino, Rieko Imae, Mao Nagase, Shiho Ohno, Noriyoshi Manabe, Yoshiki Yamaguchi, Hiroshi Manya, and Tamao Endo
- Organizer
  30th International Carbohydrate Symposium (ICS2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] ISPD欠損型筋ジストロフィーに対するCDP-リビトール誘導体を用いた治療法の開発2022
- Author(s)
  金川　基、徳岡　秀紀、今江　理恵子、星野　駿介、萬谷　博、遠藤　玉夫、戸田　達史
- Organizer
  第41回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] マウス臓器における加齢に伴う糖ヌクレオチド変化2022
- Author(s)
  今江　理恵子、萬谷　博、津元　裕樹、三浦　ゆり、遠藤　玉夫
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] CDP-エタノールアミン合成酵素PCYT2によるCDP-グリセロールの合成およびα-ジストログリカンの制御2021
- Author(s)
  今江　理恵子、萬谷　博、津元　裕樹、三浦　ゆり、遠藤　玉夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 構造解析に基づく0-マンノース型糖鎖の生合成機構2021
- Author(s)
  萬谷　博、今江　理恵子、桑原　直之、田中　智博、露口　正人、水野　真盛、加藤　龍一、遠藤　玉夫
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 筋ジストロフィー症原因遺伝子産物FKRPによるO-マンノース型糖鎖へのリビトールリン酸転移機構2021
- Author(s)
  今江　理恵子、桑原　直之、萬谷　博、加藤　龍一、遠藤　玉夫
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 筋ジストロフィー症に関わる糖転移酵素POMGNT2の基質認識の分子機構2021
- Author(s)
  露口　正人、桑原　直之、萬谷　博、今江　理恵子、田中　智博、水野　真盛、遠藤玉夫、加藤　龍一
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 哺乳動物細胞におけるリビトールリン酸生合成経路の解析2021
- Author(s)
  星野　駿介、今江　理恵子、萬谷　博、遠藤　玉夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] O-マンノース型糖鎖の伸長過程におけるFKRPによるリビトールリン酸転移機構2020
- Author(s)
  今江　理恵子、桑原　直之、萬谷　博、加藤　龍一、遠藤　玉夫
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] α-ジストログリカン糖鎖合成阻害因子CDP-グリセロールの定量分析2020
- Author(s)
  今江理恵子、萬谷博、津元裕樹、遠藤玉夫
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] リビトールリン酸転移酵素FKRPによるO-マンノース型糖鎖伸長機構2020
- Author(s)
  今江　理恵子、桑原　直之、萬谷　博、加藤　龍一、遠藤　玉夫
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] グリセロールリン酸供与体CDP-グリセロールの哺乳動物における定量分析2019
- Author(s)
  今江理恵子、萬谷博、津元裕樹、石渡俊行、遠藤玉夫
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 哺乳動物培養細胞および組織におけるCDP-グリセロールの定量分析2019
- Author(s)
  今江理恵子、萬谷博、津元裕樹、石渡俊行、遠藤玉夫
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07058
[Presentation] 新規糖鎖修飾体グリセロールリン酸によるα-ジストログリカンの機能糖鎖合成阻害2018
- Author(s)
  今江理恵子, 萬谷博, 津元裕樹, 田中智博, 水野真盛, 金川基, 小林千浩, 戸田達史, 遠藤玉夫
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-16K20996
[Presentation] CDP-glycerolはα-ジストログリカンの糖鎖伸長を阻害する2018
- Author(s)
  今江理恵子, 萬谷博, 津元裕樹, 田中智博, 水野真盛, 金川基, 小林千浩, 戸田達史, 遠藤玉夫
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K20996
[Presentation] ホスファチジルイノシトールのsn-1位の脂肪酸組成は上皮細胞のアピカルジャンクション形成に重要である2017
- Author(s)
  今江理恵子、三谷昌平、新井洋由
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K20996
[Presentation] 非対称分裂におけるホスファチジルイノシトールのsn-1位の脂肪酸組成の役割2017
- Author(s)
  今江理恵子、三谷昌平、新井洋由
- Organizer
  第69回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-16K20996
[Presentation] ホスファチジルイノシトール特異的脂肪酸転移酵素LPIAT1の成体マウスにおける生理機能解析2016
- Author(s)
  徳丸陽介, 今江理恵子, 久保卓也, Mao Yanli, 河野望, 新井洋由
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K20996
[Presentation] ホスファチジルイノシトールのsn-1位に豊富なステアリン酸の導入に関わる酵素の同定2014
- Author(s)
  今江理恵子、三谷昌平、新井洋由
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都、京都国際会館
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-24790092
[Presentation] A conditional knockout system based on the single/low-copy integration of transgenes in C. elegans.2013
- Author(s)
  E. Kage-Nakadai, R. Imae, O. Funatsu, S. Hori, Y. Suehiro, S. Yoshina, S. Mitani.
- Organizer
  19th International C. elegans Meeting
- Place of Presentation
  USA, Los Angeles, UCLA
- Data Source
  KAKENHI-PROJECT-24790092
[Presentation] Single/low-copy integration of transgenes by UV/TMP methods.2012
- Author(s)
  Eriko Kage-Nakadai, Rieko Imae, Osamu Funatsu, Sayaka Hori, Yuji Suehiro, Sawako Yoshina, and Shohei Mitani
- Organizer
  5th East Asia C. elegans meeting
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-24790092
[Presentation] Intracellular PLA1 and acyltransferase, which are involved in C. elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol2011
- Author(s)
  Rieko Imae, Takao Inoue, Masako Kimura, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai
- Organizer
  18th International C. elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22890032
[Presentation] Intracellular PLA1 and acyltransferase, which are involved in C.elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidy linositol2011
- Author(s)
  Rieko Imae, Takao Inoue, Masako Kimura, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai
- Organizer
  18^<th> International C.elegans Meeting
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22890032
[Presentation] Intracellular PLA1 and acyltransferase, which are involved in C. elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol2010
- Author(s)
  Rieko Imae, Takao Inoue, Masako Kimura, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai
- Organizer
  ASCB(the American Society for Cell Biology) 50th Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-22890032
[Presentation] Intracellular Phospholipase A_1 and Acyltransferase, Which Are Involved in Caenorhabditis elegans Stem Cell Divisions, Determine the sn-1 Fatty Acyl Chain of Phosphatidylinositol2010
- Author(s)
  Rieko Imae, Takao Inoue, Masako Kimura, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai
- Organizer
  ASCB (the American Society for Cell Biology) 50th Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-22890032
[Presentation] Intracellular Phospholipase A_1 and Acyltransferase, Which Are Involved in Caenorhabditis elegans Stem Cell Divisions, Determine the sn-1 Fatty Acyl Chain of Phosphatidylinositol2010
- Author(s)
  Rieko Imae, Takao Inoue, Masako Kimura, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai
- Organizer
  4^<th> East Asia C. elegans Meeting
- Place of Presentation
  国立オリンピック記念青少年総合センター(東京都)
- Year and Date
  2010-07-13
- Data Source
  KAKENHI-PROJECT-22890032
[Presentation] Intracellular PLA1 and acyltransferase, which are involved in C. elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol2010
- Author(s)
  Rieko Imae, Takao Inoue, Masako Kimura, Eriko Kage-Nakadai, Shohei Mitani, Hiroyuki Arai
- Organizer
  4th East Asia C. elegans Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2010-07-13
- Data Source
  KAKENHI-PROJECT-22890032
[Presentation] Characteristic fatty acid composition in the sn-1 position of phosphatidylinositol; Formation and biological significance
- Author(s)
  Rieko Imae, Shohei Mitani and Hiroyuki Arai
- Organizer
  2014 FASEB Summer Research Conference: Phospholipid Cell Signaling and Metabolism in Inflammation and Cancer
- Place of Presentation
  New York, USA
- Year and Date
  2014-06-01 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-24790092
[Presentation] Characteristic fatty acid composition in the sn-1 position of phosphatidylinositol; Formation and biological significance
- Author(s)
  Rieko Imae, Shohei Mitani and Hiroyuki Arai
- Organizer
  6th International Conference Phospholipase A2 and Lipid Mediators
- Place of Presentation
  東京、京王プラザホテル
- Year and Date
  2015-02-10 – 2015-02-12
- Data Source
  KAKENHI-PROJECT-24790092
[Presentation] Analysis of the molecular mechanisms involved in the cellular uptake of double-stranded RNA
- Author(s)
  Rieko Imae, Hiroyuki Arai and Shohei Mitani
- Organizer
  Asia-Pacific C. elegans Meeting 2014
- Place of Presentation
  奈良、奈良県新公会堂
- Year and Date
  2014-07-15 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24790092
[]
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1. NAKADAI Eriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. KANAGAWA Motoi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 萬谷博

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. 三谷昌平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 真鍋法義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 遠藤玉夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 出嶋克史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Imae Rieko 今江 理恵子

IMAE Rieko 今江 理恵子

Research Projects

Research Products

Co-Researchers

グリセロール-3-リン酸含有糖鎖の合成制御機構および癌における役割の解明Principal Investigator

Principal Investigator

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Research Institution

Investigation of the biological significance of glycerol phosphate-containing glycanPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

The biological significance of characteristic fatty acid composition of phosphatidylinositolPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the molecular mechanisms involved in the intercellular transfer of double-stranded RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biological significance of the unique fatty acid composition of phosphatidylinositol in the asymmetric division of stem cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 生体の科学 特集 脂質ワールド2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Endogenous reductase activities for the generation of ribitol-phosphate, a CDP-ribitol precursor, in mammals2023

Author(s)

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DOI

Data Source

[Journal Article] An endomembrane zinc transporter negatively regulates systemic RNAi in Caenorhabditis elegans2023

Author(s)

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DOI

Data Source

[Journal Article] Chemical and Chemo-Enzymatic Syntheses of Glycans Containing Ribitol Phosphate Scaffolding of Matriglycan2022

Author(s)

Journal Title

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Data Source

[Journal Article] CDP-ribitol prodrug treatment ameliorates ISPD-deficient muscular dystrophy mouse model2022

Author(s)

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DOI

Data Source

[Journal Article] PCYT2 synthesizes CDP-glycerol in mammals and reduced PCYT2 enhances the expression of functionally glycosylated α-dystroglycan2021

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Journal Title

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NAID

Data Source

[Journal Article] The structure of POMGNT2 provides new insights into the mechanism to determine the functional <i>O</i> ‐mannosylation site on α‐dystroglycan2021

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[Journal Article] Biosynthetic mechanisms and biological significance of glycerol phosphate-containing glycan in mammals.2021

Author(s)

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Data Source

[Journal Article] Biosynthetic Mechanisms of a Unique Ribitol Phosphate-containing Glycan by FKRP, a Ribitol Phosphate Transferase2020

Author(s)

Journal Title

DOI

Imae Rieko 今江理恵子

IMAE Rieko 今江理恵子

[Book] 生体の科学　特集　脂質ワールド2016