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Takado Yuhei  高堂 裕平

ORCIDConnect your ORCID iD *help
Researcher Number 60593564
Other IDs
Affiliation (Current) 2023: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 主幹研究員
Affiliation (based on the past Project Information) *help 2022 – 2023: 国立研究開発法人量子科学技術研究開発機構, 量子生命科学研究所, 主幹研究員
2021 – 2022: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所 脳機能イメージング研究部, 主幹研究員
2021: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 脳機能イメージング研究部, 主幹研究員(定常)
2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 脳機能イメージング研究部, 主幹研究員(任常)
2016 – 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 脳機能イメージング研究部, 研究員(任常)
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 52020:Neurology-related / Medium-sized Section 47:Pharmaceutical sciences and related fields
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Medium-sized Section 51:Brain sciences and related fields / Basic Section 08030:Family and consumer sciences, and culture and living-related
Keywords
Principal Investigator
磁気共鳴スペクトロスコピー / ポジトロン断層撮像法 / タウオパチー / バイオマーカー / MRS / アルツハイマー病 / アストロサイト / グルタミン酸 / 後部帯状回 / PET … More / 磁気共鳴スペクトロメトリー / タウ / 興奮抑制バランス / ポジトロン断層撮影 / 認知症 / 興奮・抑制バランス / 超偏極MRS … More
Except Principal Investigator
中枢性感作 / MRスペクトロスコピー / 三叉神経 / 慢性疼痛 / 代謝産物 / MR spectroscopy / 安静時fMRI / 神経障害性疼痛 / 安静時機能的MRI / Infra-slow oscillation / オシレーション / fMRI / 視覚 / 可塑性 / 磁気共鳴分光法 / 興奮抑制バランス / ニューロフィードバック / 学習 / 脳イメージング / 口腔顔面痛 / 機能的MRI / Dynamic Causal Modeling / ペプチド / 認知機能 / 海馬 / ストレス Less
  • Research Projects

    (7 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (20 People)
  •  Effects of food peptide on cognitive function and the hippocampal mechanism

    • Principal Investigator
      水重 貴文
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 08030:Family and consumer sciences, and culture and living-related
    • Research Institution
      Utsunomiya University
  •  疼痛の中枢性感作における生体内情報の処理過程に対する動的因果モデルの検証

    • Principal Investigator
      照光 真
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  超偏極MRSとDREADDによるアストロサイトイメージングバイオマーカー開発Principal Investigator

    • Principal Investigator
      高堂 裕平
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  E/I balance disruption in tau-related dementiaPrincipal Investigator

    • Principal Investigator
      Takado Yuhei
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      National Institutes for Quantum Science and Technology
  •  興奮抑制バランス操作による脳の可塑性メカニズムの理解

    • Principal Investigator
      柴田 和久
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 51:Brain sciences and related fields
    • Research Institution
      Institute of Physical and Chemical Research
  •  Central Sensitization for Neuropathic Pain in Trigeminal Nerve-Modulation of Infra-slow Oscillation

    • Principal Investigator
      TERUMITSU Makoto
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Evaluation of tau protein related neural dysfunction: PET and 3T MRS studyPrincipal Investigator

    • Principal Investigator
      Takado Yuhei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      National Institutes for Quantum and Radiological Science and Technology

All 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Neurodegenerative processes accelerated by protein malnutrition and decelerated by essential amino acids in a tauopathy mouse model2021

    • Author(s)
      Sato H、Takado Y、Toyoda S、Tsukamoto-Yasui M、Minatohara K、Takuwa H、Urushihata T、Takahashi M、Shimojo M、Ono M、Maeda J、Orihara A、Sahara N、Aoki I、Karakawa S、Isokawa M、Kawasaki N、Kawasaki M、Ueno S、Kanda M、Nishimura M、Suzuki K、Mitsui A、Nagao K、Kitamura A、Higuchi M
    • Journal Title

      Science Advances

      Volume: 7 Issue: 43 Pages: 1-11

    • DOI

      10.1126/sciadv.abd5046

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06896, KAKENHI-PROJECT-19K08005, KAKENHI-PROJECT-20K15910, KAKENHI-PUBLICLY-21H00446, KAKENHI-PUBLICLY-21H05705, KAKENHI-PROJECT-21H02818, KAKENHI-PROJECT-21K07580
  • [Journal Article] MRS-measured glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice2021

    • Author(s)
      Takado Yuhei、Takuwa Hiroyuki、Sampei Kazuaki、Urushihata Takuya、Takahashi Manami、Shimojo Masafumi、Uchida Shoko、Nitta Nobuhiro、Shibata Sayaka、Nagashima Keisuke、Ochi Yoshihiro、Ono Maiko、Maeda Jun、Tomita Yutaka、Sahara Naruhiko、Near Jamie、Aoki Ichio、Shibata Kazuhisa、Higuchi Makoto
    • Journal Title

      Journal of Cerebral Blood Flow & Metabolism

      Volume: 42 Issue: 1 Pages: 197-212

    • DOI

      10.1177/0271678x211045449

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06896, KAKENHI-PROJECT-19K08005, KAKENHI-PUBLICLY-21H00446, KAKENHI-PUBLICLY-21H05705, KAKENHI-PROJECT-19H01041, KAKENHI-PROJECT-21H02818, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K07580
  • [Journal Article] Selective Disruption of Inhibitory Synapses Leading to Neuronal Hyperexcitability at an Early Stage of Tau Pathogenesis in a Mouse Model.2020

    • Author(s)
      Shimojo M, Takuwa H, Takado Y, Tokunaga M, Tsukamoto S, Minatohara K, Ono M, Seki C, Maeda J, Urushihata T, Minamihisamatsu T, Aoki I, Kawamura K, Zhang MR, Suhara T, Sahara N, Higuchi M.
    • Journal Title

      J Neurosci.

      Volume: 40 Issue: 17 Pages: 3491-3501

    • DOI

      10.1523/jneurosci.2880-19.2020

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06542, KAKENHI-PROJECT-18K07777, KAKENHI-PROJECT-19K08005, KAKENHI-PUBLICLY-18H04752, KAKENHI-PROJECT-16H05324, KAKENHI-PROJECT-17K10387, KAKENHI-PROJECT-19K06896, KAKENHI-PROJECT-20K15910, KAKENHI-PUBLICLY-19H05437
  • [Presentation] The association between plasma and brain Glutamine and Glutamate in healthy twenties probed by LC-MS and 1H-MRS2019

    • Author(s)
      Naoto Sato, Yuhei Takado, Yuta Kanbe, Moyoko Tomiyasu, Jamie Near, Xin Lijing, Tatsuya Higashi, Tetsuya Suhara, Makoto Higuchi and Takayuki Obata
    • Organizer
      ISMRM 27TH ANNUAL MEETING & EXHIBITION
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09733
  • [Presentation] Tau protein accumulation and neurodegeneration in tauopathy model mice detected by PET and MRS2019

    • Author(s)
      Yuhei Takado, Hiroyuki Takuwa, Takuya Urushihata, Manami Takahashi, Maiko Ono, Jun Maeda, Masafumi Shimojo, Nobuhiro Nitta, Sayaka Shibata, Ichio Aoki, Naruhiko Sahara, Tetsuya Suhara, Makoto Higuchi
    • Organizer
      BRAIN & BRAIN PET 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08005
  • [Presentation] MRSを用いたin vivo脳内タウリン濃度測定:マウスからヒトまで2018

    • Author(s)
      高堂 裕平 , 田桑 弘之 , 下條 雅文 , 小野 麻衣子 , 塚本 智史 , 青木 伊知男 , 小畠 隆行 , 東 達也 , 佐原 成彦 , 須原 哲也 , 樋口 真人
    • Organizer
      第4回国際タウリン研究会日本部会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09733
  • [Presentation] SNR comparison of 1H-MRS sequences: SPECIAL vs PRESS2017

    • Author(s)
      佐藤直人,高堂裕平,富安もよこ,Lijing Xin, Jamie Near,吉川宏起,樋口真人,小畠隆行
    • Organizer
      第45回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-16K09733
  • [Presentation] 1H-MRS 用シーケンス SPECIAL と PRESS における信号雑音比の比較2017

    • Author(s)
      佐藤 直人, 高堂 裕平, 富安 もよこ, Hyerin Oh, Jamie Near, 吉川 宏起, 樋口 真人, 小畠 隆行
    • Organizer
      第 29 回 臨床 MR 脳機能研究会
    • Place of Presentation
      損保会館(東京都・千代田区)
    • Year and Date
      2017-04-08
    • Data Source
      KAKENHI-PROJECT-16K09733
  • 1.  TERUMITSU Makoto (60401767)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  福田 謙一 (80228907)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  瀬尾 憲司 (40242440)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  大塚 有紀子 (30815767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  倉田 行伸 (20464018)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  吉本 裕代 (40453287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  金澤 香 (40453279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  大桶 華子 (90295907)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  柴田 和久 (20505979)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  高野 正行 (50197117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  梅田 聡 (90317272)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  水重 貴文 (70571008)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  鈴木 智大 (10649601)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  蕪山 由己人 (20285042)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SUHARA Tetsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  SHIMADA Hitoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  IKOMA Yoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  OBATA Takayuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 19.  TAKUWA Hiroyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  佐原 成彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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