Ootake Hiromasa 大竹寛雅

… Alternative Names

Otake Hiromasa 大竹寛雅

Less

Researcher Number	60593803
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 神戸大学, 医学部附属病院, 准教授 2017 – 2021: 神戸大学, 医学部附属病院, 講師 2015 – 2016: 神戸大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator OCT / 不安定プラーク / 数値流体力学解析 / plaque structural stress / 数値流体解析 / wall shear stress / 冠動脈疾患 / acute coronary syndrome / vulnerable plaque / computed tomography … More / thin cap fibroatheroma / Shear stress / プラークの不安定化 / 血行力学的因子 / ずり応力 … More Except Principal Investigator eQTL解析 / マルチオミックス解析 / クローン性造血 / T細胞レパトア解析 / マクロファージ / 動脈硬化 / シングルセル解析 / 心房繊維化 / モノサイト / 炎症性単球 / PETMRI / LGEMRI / 心房炎症 / 炎症 / 心房線維化 / LGE-MRI / カテーテルアブレーション / 心房細動 Less

Clarifying the mechanisms of atherosclerotic cardiovascular diseases via genome and single cell integrated omics analyses.
- Principal Investigator
  
  平田健一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
An exploratory study to identify high-risk plaques using stress evaluation within coronary plaquesPrincipal Investigator
- Principal Investigator
  
  Otake Hiromasa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Catheter ablation for atrial fibrosis and inflammation in patients with persistent atrial fibrillation
- Principal Investigator
  
  kiuchi kunihiko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kobe University
Hemodynamic approach for the evaluation of patients with ischemic heart diseasePrincipal Investigator
- Principal Investigator
  
  Otake Hiromasa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kobe University

All 2024 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Single-Cell RNA Sequencing Reveals an Immune Landscape of CD4 <sup>+</sup> T Cells in Coronary Culprit Plaques With Acute Coronary Syndrome in Humans2024
- Author(s)
  Takeda Shintaro、Emoto Takuo、Yamashita Tomoya、Yamamoto Hiroyuki、Takaya Tomofumi、Sawada Takahiro、Yoshida Takeshi、Inoue Masatoshi、Suzuki Yuya、Hamana Tomoyo、Inoue Taishi、Taniguchi Masayuki、Sasaki Naoto、Otake Hiromasa、Ohkawa Takenao、Furuyashiki Tomoyuki、Kawai Hiroya、Hirata Ken-ichi
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: - Issue: 5 Pages: 1135-1143
- DOI
  10.1161/atvbaha.123.320409
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06359, KAKENHI-PROJECT-22K16105, KAKENHI-PUBLICLY-23H04234, KAKENHI-PROJECT-21H04812, KAKENHI-PROJECT-23K27596
[Journal Article] Lumen Boundaries Extracted from Coronary Computed Tomography Angiography on Computed Fractional Flow Reserve (FFRCT): Validation with Optical Coherence Tomography.2018
- Author(s)
  Kenzo Uzu, Hiromasa Otake, Gilwoo Choi, Takayoshi Toba, Hyun Jin Kim, Arjun Roy, Michiel Schaap, Leo Grady, Masahito Kawata, Toshiro Shinke, Charles A. Taylor, Ken-ichi Hirata
- Journal Title
  
  EuroIntervention
  
  Volume: 印刷中 Issue: 15 Pages: e1609-e1618
- DOI
  10.4244/eij-d-17-01132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Journal Article] Computational fluid dynamic measures of wall shear stress are related to coronary lesion characteristics2016
- Author(s)
  Park JB, Choi G, Chun EJ, Kim HJ, Park J, Jung JH, Lee MH, Otake H, Doh JH, Nam CW, Shin ES, De Bruyne B, Taylor CA, Koo BK.
- Journal Title
  
  Heart
  
  Volume: 102(20) Issue: 20 Pages: 1655-1661
- DOI
  10.1136/heartjnl-2016-309299
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Journal Article] Coronary Artery Axial Plaque Stress and its Relationship With Lesion Geometry: Application of Computational Fluid Dynamics to Coronary CT Angiography.2015
- Author(s)
  Choi G, Lee JM, Kim HJ, Park JB, Sankaran S, Otake H, Doh JH, Nam CW, Shin ES, Taylor CA, Koo BK.
- Journal Title
  
  journal of american college of cardiology cardiovascular imaging
  
  Volume: 印刷中 Issue: 10 Pages: 1156-1166
- DOI
  10.1016/j.jcmg.2015.04.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Journal Article] Computational replication of the patient-specific stenting procedure for coronary artery bifurcations: From OCT and CT imaging to structural and hemodynamics analyses.2015
- Author(s)
  Chiastra C, Wu W, Dickerhoff B, Aleiou A, Dubini G, Otake H, Migliavacca F LaDisa JF Jr
- Journal Title
  
  J Biotech.
  
  Volume: 印刷中 Issue: 11 Pages: 2102-2111
- DOI
  10.1016/j.jbiomech.2015.11.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] High Wall Shear Stress Was Strongly Associated with Plaque Vulnerability in Combined Optical Coherence Tomography and Heartflow FFRCT Simulation.2018
- Author(s)
  Takayoshi Toba, Gilwoo Choi, Yuichiro Nagano, Ryo Takeshige, Shumpei Mori, Toshiro Shinke, Charles Taylor, Hiromasa Otake
- Organizer
  日本循環器学会総会日本
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] Why does thin-cap fibroatheroma cluster in the proximal segment in left anterior coronary artery, but are evenly distributed throughout the entire right coronary artery? ;Results from computational fluid dynamics simulation by CT-FFR-2017
- Author(s)
  鳥羽敬義, Gilwoo Choi,Hyun Jin Kim, Arjun Roy, Tran Nguyen, Michiel Schaa, Leo Grady, 宇津賢三, 森俊平, 新家俊郎, Bon-Kwon Koo, Charles Taylor, 大竹寛雅
- Organizer
  第81回日本循環器学会学術集会金沢
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] High Wall Shear Stress Was Strongly Associated with Plaque Vulnerability in Computational Fluid Dynamics with Combined Optical Coherence Tomography and Heartflow FFRCT Simulation.2017
- Author(s)
  Takayoshi Toba, Gilwoo Choi, Yuichiro Nagano, Ryo Takeshige, Shumpei Mori, Toshiro Shinke, Charles Taylor, Hiromasa Otake
- Organizer
  TCT 2017 米国デンバー
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] プラークの不安定化に対する新規アプローチ-血行力学的評価の重要性-2016
- Author(s)
  大竹　寛雅
- Organizer
  第25回日本心血管インターベンション治療学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-07-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] Impact of Wall Shear Stress and Axial Plaque Stress on Coronary Plaque Initiation and Progression2016
- Author(s)
  Takayoshi Toba, Gilwoo Choi, Hyun Jin Kim, Arjun Roy, Tran Nguyen, Michiel Schaap, Leo Grady, Kenzo Uzu, Shumpei Mori, Tomofumi Takaya, Toshiro Shinke, Bon-Kwon Koo, Charles Taylor, Hiromasa Otake
- Organizer
  American college of cardiology 2016
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] Correlation of Wall Shear Stress and Axial Plaque Stress between models derived from CT and OCT data2016
- Author(s)
  Gilwoo Choi, Kenzo Uzu, Takayoshi Toba, Hyun Jin Kim, Arjun Roy, Tran Nguyen, Bon-Kwon Koo, Leo Grady, Charles Taylor, Hiromasa Otake
- Organizer
  American college of cardiology 2016
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] Evaluation of local hemodynamic forces acting on plaque may help predict plaque vulnerability; Lessons from combined analysis of optical coherence tomography and computational fluid dynamics simulation2016
- Author(s)
  Kenzo Uzu, Gilwoo Choi,, Hyun Jin Kim, Arjun Roy, Tran Nguyen, Michiel Schaap, Leo Grady, Takayoshi Toba, Shumpei Mori, Tomofumi Takaya, Toshiro Shinke, Bon-Kwon Koo, Charles Taylor, Hiromasa Otake
- Organizer
  American college of cardiology 2016
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120
[Presentation] Impact of precision of lumen boundary extracted from coronary CT on FFRCT: validation with OCT2016
- Author(s)
  Takayoshi Toba, Gilwoo Choi, Kenzo Uzu, Hyun Jin Kim, Arjun Roy, Tran Nguyen, Michiel Schaap, Leo Grady, Shumpei Mori, Tomofumi Takaya, Toshiro Shinke, Bon-Kwon Koo, Charles Taylor, Hiromasa Otake
- Organizer
  American college of cardiology 2016
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09120

1. kiuchi kunihiko (50777612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 新家俊郎 (60379419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 福沢公二 (70535856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 佐々木直人 (00514746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 清家史靖 (10771561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 保田和則 (80239756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 平田健一 (20283880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 井上大志 (50868487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山中勝弘 (70729384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 江本拓央 (80855023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 岡田健次 (90284356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山下智也 (90437468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 谷口将之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ootake Hiromasa 大竹 寛雅

Otake Hiromasa 大竹 寛雅

Research Projects

Research Products

Co-Researchers

Clarifying the mechanisms of atherosclerotic cardiovascular diseases via genome and single cell integrated omics analyses.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An exploratory study to identify high-risk plaques using stress evaluation within coronary plaquesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Catheter ablation for atrial fibrosis and inflammation in patients with persistent atrial fibrillation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hemodynamic approach for the evaluation of patients with ischemic heart diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Single-Cell RNA Sequencing Reveals an Immune Landscape of CD4 <sup>+</sup> T Cells in Coronary Culprit Plaques With Acute Coronary Syndrome in Humans2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lumen Boundaries Extracted from Coronary Computed Tomography Angiography on Computed Fractional Flow Reserve (FFRCT): Validation with Optical Coherence Tomography.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational fluid dynamic measures of wall shear stress are related to coronary lesion characteristics2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coronary Artery Axial Plaque Stress and its Relationship With Lesion Geometry: Application of Computational Fluid Dynamics to Coronary CT Angiography.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational replication of the patient-specific stenting procedure for coronary artery bifurcations: From OCT and CT imaging to structural and hemodynamics analyses.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] High Wall Shear Stress Was Strongly Associated with Plaque Vulnerability in Combined Optical Coherence Tomography and Heartflow FFRCT Simulation.2018

Author(s)

Organizer

Data Source

[Presentation] Why does thin-cap fibroatheroma cluster in the proximal segment in left anterior coronary artery, but are evenly distributed throughout the entire right coronary artery? ;Results from computational fluid dynamics simulation by CT-FFR-2017

Author(s)

Organizer

Data Source

[Presentation] High Wall Shear Stress Was Strongly Associated with Plaque Vulnerability in Computational Fluid Dynamics with Combined Optical Coherence Tomography and Heartflow FFRCT Simulation.2017

Author(s)

Organizer

Data Source

[Presentation] プラークの不安定化に対する新規アプローチ-血行力学的評価の重要性-2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Impact of Wall Shear Stress and Axial Plaque Stress on Coronary Plaque Initiation and Progression2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Correlation of Wall Shear Stress and Axial Plaque Stress between models derived from CT and OCT data2016

Author(s)

Ootake Hiromasa 大竹寛雅

Otake Hiromasa 大竹寛雅