Takahashi Ken 高橋健

… Alternative Names

TAKAHASHI Ken 高橋健

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Researcher Number	60594372
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2023: 京都大学, 医学研究科, 准教授 2022: 公益財団法人田附興風会, 医学研究所腫瘍研究部, 研究員 2017 – 2021: 京都大学, 医学研究科, 助教 2011 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2012: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator ワクチン / 自然免疫 / がん免疫 / 膵癌 / 消化器がん / 肝臓病学 / 免疫学 / 光免疫療法 / TLR9 / 肝細胞癌 … More / 肝がん / 消化器癌 / 肝炎ウイルス / ウイルス肝炎 / 免疫 / 感染症 / ウイルス Less

光免疫療法を組み込んだin situワクチンによる消化器がんの術前免疫療法の開発Principal Investigator
- Principal Investigator
  
  高橋健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyoto University
Preclinical study of near-infrared photoimmunotherapy for pancreatic cancer that incorporates nanoparticulate TLR9 agonist K3-SPGPrincipal Investigator
- Principal Investigator
  
  Ken Takahashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The Tazuke Kofukai
  Kyoto University
Preclinical study of in situ vaccine immunotherapy for hepatocellular carcinoma targeting TLR9 and RIG-IPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Ken
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Comprehensive analysis of immune response in hapatitis B using novel disease mouse modelPrincipal Investigator
- Principal Investigator
  
  Takahashi Ken
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Dissecting themechanism of plasmacytoid dendritic cell activation triggered by hepatitis C virus-infected cellsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Ken
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University

All 2023 2022 2016 2015 2014 2012

All Journal Article Presentation Patent

[Journal Article] In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy2022
- Author(s)
  Okada H, Takahashi K, Yaku H, Kobiyama K, Iwaisako K, Zhao X, Shiokawa M, Uza N, Kodama Y, Ishii KJ, Seno H.
- Journal Title
  
  Sci Rep.
  
  Volume: 12 Issue: 1 Pages: 2132-2132
- DOI
  10.1038/s41598-022-05702-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-20K08996, KAKENHI-PROJECT-21K20802, KAKENHI-PROJECT-20K08329
[Journal Article] Mouse models of hepatitis B virus infection comprising host-virus immunologic interactions2014
- Author(s)
  Inuzuka T, Takahashi K, Chiba T, Marusawa H.
- Journal Title
  
  Pathogens
  
  Volume: 3 Issue: 2 Pages: 377-389
- DOI
  10.3390/pathogens3020377
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J02056, KAKENHI-PROJECT-25460991
[Journal Article] Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro2014
- Author(s)
  Wieland SF, Takahashi K, Boyd B, Whitten-Bauer C, Ngo N, de la Torre JC, Chisari FV.
- Journal Title
  
  Journal of Virology
  
  Volume: 88 Issue: 1 Pages: 752-757
- DOI
  10.1128/jvi.01714-13
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460991
[Journal Article] Dynamics of Hepatitis B Virus Quasispecies in Association with Nucleos(t)ide Analogue Treatment Determined by Ultra-Deep Sequencing.2012
- Author(s)
  Nishijima N
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 4 Pages: 35052-35052
- DOI
  10.1371/journal.pone.0035052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590972, KAKENHI-PROJECT-23790790, KAKENHI-PROJECT-24229005
[Patent] がん特異的細胞表面分子に対する結合性分子および光感受性分子の複合体ならびにアジュバントを含む医薬2022
- Inventor(s)
  高橋健
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-171961
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K08329
[Patent] がん特異的細胞表面分子に対する結合性分子および光感受性分子の複合体ならびにアジュバントを含む医薬2022
- Inventor(s)
  高橋健
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Overseas
- Data Source
  KAKENHI-PROJECT-20K08329
[Presentation] In situ vaccine combining TLR9 nanoligand K3-SPG and near-infrared photoimmu notherapy evokes potent antitumor immunity2023
- Author(s)
  Hiroaki Yaku, Ken Takahashi, Hirokazu Okada, Kouji Kobiyama, Masahiro Shiokawa, Norimitsu Uza, Ken J. Ishii, Hiroshi Seno
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07386
[Presentation] RNA-seq analysis of innate immune response in hepatitis B2016
- Author(s)
  Ken Takahashi
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  SanDiego, CA, USA
- Year and Date
  2016-05-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460991
[Presentation] B型肝炎の免疫応答解析におけるRNA-seqの有用性2015
- Author(s)
  高橋健
- Organizer
  第41回日本肝臓学会西部会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-25460991
[Presentation] C型肝炎ウイルス薬剤耐性クローンの次世代ゲノムアナライザー解析2012
- Author(s)
  高橋健
- Organizer
  第54回日本消化器病学会大会 (JDDW 2012)
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Data Source
  KAKENHI-PROJECT-23790790
[Presentation] C 型肝炎ウイルス薬剤耐性クローンの次世代ゲノムアナライザー解析2012
- Author(s)
  高橋健他
- Organizer
  第54回日本消化器病学会大会(JDDW 2012)
- Place of Presentation
  神戸ポートピアホテル (神戸)
- Year and Date
  2012-10-10
- Data Source
  KAKENHI-PROJECT-23790790
[Presentation] C型肝炎ウイルス感染細胞による形質細胞様樹状細胞活性化とその分子機序の解明2012
- Author(s)
  高橋健
- Organizer
  Liver Forum in Kyoto
- Place of Presentation
  ホテルオークラ京都（京都府）
- Data Source
  KAKENHI-PROJECT-23790790

1. 石井健 (00448086)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 宇座徳光 (30447958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 妹尾浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Ken 高橋 健

TAKAHASHI Ken 高橋 健

Research Projects

Research Products

Co-Researchers

光免疫療法を組み込んだin situワクチンによる消化器がんの術前免疫療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preclinical study of near-infrared photoimmunotherapy for pancreatic cancer that incorporates nanoparticulate TLR9 agonist K3-SPGPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preclinical study of in situ vaccine immunotherapy for hepatocellular carcinoma targeting TLR9 and RIG-IPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of immune response in hapatitis B using novel disease mouse modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Dissecting themechanism of plasmacytoid dendritic cell activation triggered by hepatitis C virus-infected cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In situ vaccination using unique TLR9 ligand K3-SPG induces long-lasting systemic immune response and synergizes with systemic and local immunotherapy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mouse models of hepatitis B virus infection comprising host-virus immunologic interactions2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamics of Hepatitis B Virus Quasispecies in Association with Nucleos(t)ide Analogue Treatment Determined by Ultra-Deep Sequencing.2012

Author(s)

Journal Title

DOI

Data Source

[Patent] がん特異的細胞表面分子に対する結合性分子および 光感受性分子の複合体ならびにアジュバントを含む医薬2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] がん特異的細胞表面分子に対する結合性分子および光感受性分子の複合体ならびにアジュバントを含む医薬2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] In situ vaccine combining TLR9 nanoligand K3-SPG and near-infrared photoimmu notherapy evokes potent antitumor immunity2023

Author(s)

Organizer

Data Source

[Presentation] RNA-seq analysis of innate immune response in hepatitis B2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] B型肝炎の免疫応答解析におけるRNA-seqの有用性2015

Author(s)

Takahashi Ken 高橋健

TAKAHASHI Ken 高橋健

[Patent] がん特異的細胞表面分子に対する結合性分子および光感受性分子の複合体ならびにアジュバントを含む医薬2022