Kinoshita Masaharu 木下正治

Researcher Number	60599083
Other IDs	https://orcid.org/0000-0001-8588-843X
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定准教授
Affiliation (based on the past Project Information) *help	2024: 弘前大学, 医学研究科, 准教授 2016 – 2022: 弘前大学, 医学研究科, 准教授 2015: 弘前大学, 大学院医学研究科, 准教授 2013 – 2015: 弘前大学, 医学(系)研究科(研究院), 准教授
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Neurophysiology / General neuroscience / Biological Sciences Except Principal Investigator Neurophysiology / General neuroscience
Keywords	Principal Investigator 光遺伝学 / ウイルスベクター / マカクザル / 視覚情報処理 / 神経科学 / 盲視 / optogenetics / 知覚的充填 / neural pathway / macaque monkey … More / gene introduction / 霊長類 / 経路選択的神経伝達遮断 / 神経経路 / サッケード / 遺伝子導入 / 上丘 / 視床枕 … More Except Principal Investigator 行動選択 / 運動制御 / 大脳皮質 / 大脳基底核 / ニホンザル / 光遺伝学 / ニューロン活動 / 随意運動 / 大脳基底核連関 / オプトジェネティクス / optogenetics / neuronal activity / reaching / motor control / cerebellum / basal ganglia Less

光遺伝学を非ヒト霊長類に応用して経路選択的な神経伝達の操作を実現するPrincipal Investigator
- Principal Investigator
  
  木下正治
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Hirosaki University
Blockade of specific neural pathway in non human primates brain by using optogenetic method.Principal Investigator
- Principal Investigator
  
  KINOSHITA MASAHARU
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Hirosaki University
A new artificial scotoma model by optogenetics and neural mechanisms of perceptual filling inPrincipal Investigator
- Principal Investigator
  
  Kinoshita Masaharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Hirosaki University
光遺伝学を用いた霊長類の視覚－運動変換系の神経経路選択的な伝達遮断法の確立Principal Investigator
- Principal Investigator
  
  木下正治
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hirosaki University
Identification of functional role of neural networks between basal ganglia and cerebral cortex by optogenetics
- Principal Investigator
  
  Kurata Kiyoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Hirosaki University
Study about the superior colliculus related neural pathway for blindsight by using new genetic methodPrincipal Investigator
- Principal Investigator
  
  Kinoshita Masaharu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Hirosaki University

All 2022 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] Phylogenetic view of the compensatory mechanisms in motor and sensory systems after neuronal injury2022
- Author(s)
  Isa Tadashi、Tohyama Takamichi、Kinoshita Masaharu
- Journal Title
  
  Current Research in Neurobiology
  
  Volume: 3 Pages: 100058-100058
- DOI
  10.1016/j.crneur.2022.100058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06880, KAKENHI-PROJECT-19KK0192, KAKENHI-PLANNED-19H05723, KAKENHI-PROJECT-22H04992
[Journal Article] Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration2019
- Author(s)
  Tu Hung-Ya、Watanabe Takehito、Shirai Hiroshi、Yamasaki Suguru、Kinoshita Masaharu、Matsushita Keizo、Hashiguchi Tomoyo、Onoe Hirotaka、Matsuyama Take、Kuwahara Atsushi、Kishino Akiyoshi、Kimura Toru、Eiraku Mototsugu、Suzuma Kiyoshi、Kitaoka Takashi、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  EBioMedicine
  
  Volume: 39 Pages: 562-574
- DOI
  10.1016/j.ebiom.2018.11.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994, KAKENHI-PROJECT-16K06983
[Journal Article] Dissecting the circuit for blindsight to reveal the critical role of pulvinar and superior colliculus2019
- Author(s)
  Kinoshita M, Kato R, Isa K, Kobayashi K, Kobayashi K, Onoe H, Isa T
- Journal Title
  
  Nat Commun
  
  Volume: 10 Issue: 1 Pages: 135-135
- DOI
  10.1038/s41467-018-08058-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06535, KAKENHI-PLANNED-26112002, KAKENHI-PLANNED-26112003, KAKENHI-PLANNED-26112008, KAKENHI-PROJECT-26221003, KAKENHI-PROJECT-16K06983
[Journal Article] Contribution of propriospinal neurons to recovery of hand dexterity after corticospinal tract lesions in monkeys.2017
- Author(s)
  Tohyama, T., Kinoshita, M., Kobayashi, K., Isa, K., Watanabe, D., Kobayashi, K., Liu, M., and Isa, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 114 Issue: 3 Pages: 604-609
- DOI
  10.1073/pnas.1610787114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26112002, KAKENHI-PLANNED-26112008, KAKENHI-PROJECT-24220009, KAKENHI-PROJECT-26221003, KAKENHI-PROJECT-15K14315, KAKENHI-PROJECT-16K06983, KAKENHI-PUBLICLY-15H01411, KAKENHI-PLANNED-26112007
[Presentation] Transplantation of human induced pluripotent stem cell-derived retinal tissue in primate models of retinal degeneration with perimetric analysis2016
- Author(s)
  Hiroshi Shirai, Michiko Mandai, Masaharu Kinoshita, Hirotaka Onoe, Keizo Matsushita, Atsushi Kuwahara, Suguru Yamasaki, Hiroko Terasaki, Yoshiki Sasai, Masayo Takahashi
- Organizer
  ARVO 2016 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01411
[Presentation] Pulvinar inactivation impairs the visually guided saccade in the blindsight monkeys.2015
- Author(s)
  M. KINOSHITA, R. KATO, K. ISA, K. KOBAYASHI, H. ONOE, T. ISA
- Organizer
  Neuroscience 2015 (Society for Nuroscience)
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430023
[Presentation] Pulvinar inactivation impairs performance of the visually guided saccade in the blindsight monkeys.2015
- Author(s)
  木下正治、加藤利佳子、伊佐かおる、小林憲太、尾上浩隆、伊佐正
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県、神戸市）
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-25430023

1. Kurata Kiyoshi (30170070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Tu HungYa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 小林和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小林憲太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kinoshita Masaharu 木下 正治

Research Projects

Research Products

Co-Researchers

光遺伝学を非ヒト霊長類に応用して経路選択的な神経伝達の操作を実現するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Blockade of specific neural pathway in non human primates brain by using optogenetic method.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A new artificial scotoma model by optogenetics and neural mechanisms of perceptual filling inPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

光遺伝学を用いた霊長類の視覚－運動変換系の神経経路選択的な伝達遮断法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of functional role of neural networks between basal ganglia and cerebral cortex by optogenetics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study about the superior colliculus related neural pathway for blindsight by using new genetic methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Phylogenetic view of the compensatory mechanisms in motor and sensory systems after neuronal injury2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Medium- to long-term survival and functional examination of human iPSC-derived retinas in rat and primate models of retinal degeneration2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dissecting the circuit for blindsight to reveal the critical role of pulvinar and superior colliculus2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Contribution of propriospinal neurons to recovery of hand dexterity after corticospinal tract lesions in monkeys.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Transplantation of human induced pluripotent stem cell-derived retinal tissue in primate models of retinal degeneration with perimetric analysis2016

Author(s)

Organizer

Data Source

[Presentation] Pulvinar inactivation impairs the visually guided saccade in the blindsight monkeys.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Pulvinar inactivation impairs performance of the visually guided saccade in the blindsight monkeys.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Kinoshita Masaharu 木下正治