Takayama Yuzo 高山祐三

Researcher Number	60608438
Other IDs	https://orcid.org/0000-0002-6382-8767
Affiliation (Current)	2025: 芝浦工業大学, システム理工学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 芝浦工業大学, システム理工学部, 准教授 2020 – 2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2021: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ付 2017: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2015 – 2016: 国立研究開発法人産業技術総合研究所, 創薬基盤研究部門, 研究員 2014: 独立行政法人産業技術総合研究所, その他部局等, 研究員 2013 – 2014: 独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 研究員
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Basic Section 90110:Biomedical engineering-related / Medium-sized Section 90:Biomedical engineering and related fields Except Principal Investigator Basic Section 28050:Nano/micro-systems-related / Basic Section 47060:Clinical pharmacy-related / Basic Section 90110:Biomedical engineering-related / Plastic surgery
Keywords	Principal Investigator ヒトiPS細胞 / 自律神経 / 微細加工 / 交感神経 / 生体外再構築 / 生体モデリング / 血管 / 幹細胞 / 糖尿病 / 汗腺 … More / 再生医療 / 再生、細胞移植 / 循環器・高血圧 / ヒト多能性幹細胞 / 副交感神経 / 心筋細胞 / 心筋 / 自律神経細胞 / 生物・生体工学 / 再生医工学 / 神経細胞 … More Except Principal Investigator organs-on-chip / MPS / Organ-on-chip / 自律神経 / 血管 / 灌流 / Drug screening / In vitro model / 中枢神経系疾患 / in vitro / 生体模倣システム / 血液脳関門 / 微小電極アレイ / 脱髄 / 感覚神経細胞 / マイクロ加工 / 疼痛 / 末梢神経 / ミエリン鞘 / 電気計測 / 軸索 / 顔面神経不全麻痺モデル / 坐骨神経損傷モデル / 脂肪由来幹細胞 / 人工神経 / 末梢神経再生 Less

Creation of 3D tissue culture system integrated with blood vessels and autonomic nerves
- Principal Investigator
  
  森宣仁
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28050:Nano/micro-systems-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Construction of an in vitro blood vessel model that reproduces the hypertension state and its application to assay systemsPrincipal Investigator
- Principal Investigator
  
  高山祐三
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Shibaura Institute of Technology
  National Institute of Advanced Industrial Science and Technology
In Vitro Construction of Human Sweat Gland FunctionPrincipal Investigator
- Principal Investigator
  
  高山祐三
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
ヒト脳マイクロパソフィジオロジカルシステムズ：脳疾患の生体模倣と創薬研究への応用
- Principal Investigator
  
  降幡知巳
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Construction of an On-Chip Cardiomyocyte Model incorporated with Autonomic NeuronsPrincipal Investigator
- Principal Investigator
  
  Takayama Yuzo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Studying Intracellular Mechanisms of Pain Information Generation by High-Resolution Electrical Measurement
- Principal Investigator
  
  Shimba Kenta
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Reconstruction of sympathetic neuron-vascular interactions in vitro and its applicationsPrincipal Investigator
- Principal Investigator
  
  Takayama Yuzo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Introduction of some kind of artificial axon to peripheral nerve repair
- Principal Investigator
  
  Sekido Mitsuru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Plastic surgery
- Research Institution
  University of Tsukuba
Production of pancreatic beta cells/neurons in the autonomic nervous system and neural interface applicationPrincipal Investigator
- Principal Investigator
  
  Takayama Yuzo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institute of Advanced Industrial Science and Technology
神経インターフェース技術に基づいたインスリン分泌制御手法の開発とデバイス化Principal Investigator
- Principal Investigator
  
  高山祐三
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2023 2020 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book Patent

[Book] 臓器チップの技術と開発動向2018
- Author(s)
  高山祐三、木田泰之、他
- Total Pages
  293
- Publisher
  シーエムシー出版
- ISBN
  9784781313252
- Data Source
  KAKENHI-PROJECT-26702015
[Book] 臓器チップの技術と開発動向2018
- Author(s)
  高山祐三、木田泰之、他
- Total Pages
  293
- Publisher
  シーエムシー出版
- ISBN
  9784781313252
- Data Source
  KAKENHI-PROJECT-16K12887
[Journal Article] Deciphering the Molecular Mechanisms of Autonomic Nervous System Neuron Induction through Integrative Bioinformatics Analysis2023
- Author(s)
  Yuzo Takayama, Yuka Akagi, Yasuyuki S. Kida
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 10 Pages: 9053-9053
- DOI
  10.3390/ijms24109053
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K28419
[Journal Article] Brief Exposure to Small Molecules Allows Induction of Mouse Embryonic Fibroblasts into Neural Crest-like Precursors2017
- Author(s)
  高山祐三、若林珠実、櫛笥博子、齋藤裕、渋谷陽一郎、芝田晋介、赤松和土、岡野栄之、木田泰之
- Journal Title
  
  FEBS Letters
  
  Volume: 591 Issue: 4 Pages: 590-602
- DOI
  10.1002/1873-3468.12572
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26702015, KAKENHI-PROJECT-15K15649, KAKENHI-PROJECT-15K16089
[Journal Article] In Vitro Reconstruction of Neuronal Networks Derived from Human iPS Cells Using Microfabricated Devices2016
- Author(s)
  Yuzo Takayama and Yasuyuki S Kida
- Journal Title
  
  PLOS ONE
  
  Volume: Vol. 11(2) Issue: 2 Pages: e0148559-e0148559
- DOI
  10.1371/journal.pone.0148559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15649, KAKENHI-PROJECT-26702015
[Journal Article] Induced Current-Pharmacological Split Stimulation System for Neuronal Networks2014
- Author(s)
  Saito A., Takayama Y., Kotani K., Jimbo Y.
- Journal Title
  
  IEEE Trans. BME
  
  Volume: 61 Issue: 2 Pages: 463-472
- DOI
  10.1109/tbme.2013.2281079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240065, KAKENHI-PROJECT-25882056
[Journal Article] Neural Transplantation Model Using Integration Co-Culture Chamber2014
- Author(s)
  Kenta Shimba, Atsushi Saito, Akimasa Takeuchi, Yuzo Takayama, Kiyoshi Kotani and Yasuhiko Jimbo
- Journal Title
  
  Electronics and Communications in Japan
  
  Volume: 97 Issue: 2 Pages: 36-43
- DOI
  10.1002/ecj.11523
- NAID
  210000185007
- Data Source
  KAKENHI-PROJECT-25882056
[Journal Article] Efficient Sequential Bayesian Inference Method for Real-time Detection and Sorting of Overlapped Neural Spikes2013
- Author(s)
  Tatsuya Haga, Osamu Fukayama, Yuzo Takayama, Takayuki Hoshino, Kunihiko Mabuchi
- Journal Title
  
  Journal of Neuroscience Methods
  
  Volume: Vol.219 Issue: 1 Pages: 92-103
- DOI
  10.1016/j.jneumeth.2013.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J09939, KAKENHI-PROJECT-25882056
[Journal Article] Effects of electric field stimulation timing on calcium dynamics of cultured cardiomyocytes2013
- Author(s)
  Leo Miyashita, Yuzo Takayama, Tatsuya Haga, Takafumi Suzuki, Kunihiko Mabuchi
- Journal Title
  
  IEEJ Transactions on Electrical and Electronic Engineering
  
  Volume: 8 Issue: S1
- DOI
  10.1002/tee.21927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25882056
[Patent] 神経堤細胞から自律神経系の細胞への分化誘導方法2016
- Inventor(s)
  木田泰之、高山祐三
- Industrial Property Rights Holder
  木田泰之、高山祐三
- Industrial Property Rights Type
  特許
- Filing Date
  2016-04-26
- Overseas
- Data Source
  KAKENHI-PROJECT-26702015
[Patent] 神経堤細胞から自律神経系の細胞への分化誘導方法2015
- Inventor(s)
  木田泰之、高山祐三
- Industrial Property Rights Holder
  木田泰之、高山祐三
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-112237
- Filing Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] Specification of peripheral neurons from human pluripotent stem cells allows construction of nerve-innervating culture models2020
- Author(s)
  高山祐三、赤木祐香、木田泰之
- Organizer
  FENS Forum 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12613
[Presentation] 自律神経を備えたヒト培養組織の構築とその応用2020
- Author(s)
  高山祐三
- Organizer
  CBI学会2020年大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12613
[Presentation] Selective derivation of human peripheral neurons in the autonomic nervous system facilitate precise control of cardiomyocyte beating2020
- Author(s)
  高山祐三、櫛笥博子、赤木祐香、鈴木　穣、熊谷雄太郎、木田泰之
- Organizer
  ISSCR 2020 Virtual
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K12613
[Presentation] ヒト多能性幹細胞からの自律神経細胞誘導とその応用2017
- Author(s)
  高山祐三、若林玲実、櫛笥博子、木田泰之
- Organizer
  平成29年電気学会電子・情報・システム部門大会
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] Brief Exposure to Small Molecular Compounds Allows Induction of Mouse Embryonic Fibroblasts into Neural Crest-Like Precursors2017
- Author(s)
  高山祐三、若林玲実、櫛笥博子、齋藤裕、渋谷陽一郎、芝田　晋介、赤松　和土、岡野　栄之、木田泰之
- Organizer
  ISSCR2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] Brief Exposure to Small Molecular Compounds Allows Induction of Mouse Embryonic Fibroblasts into Neural Crest-Like Precursors2017
- Author(s)
  高山祐三、若林玲実、櫛笥博子、齋藤裕、渋谷陽一郎、芝田　晋介、赤松　和土、岡野　栄之、木田泰之
- Organizer
  ISSCR2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K12887
[Presentation] ヒト多能性幹細胞からの自律神経細胞誘導とその応用2017
- Author(s)
  高山祐三、若林玲実、櫛笥博子、木田泰之
- Organizer
  平成29年電気学会電子・情報・システム部門大会
- Data Source
  KAKENHI-PROJECT-16K12887
[Presentation] 微細加工技術を用いた末梢神経細胞と膵b細胞との共培養2017
- Author(s)
  高山祐三、木田泰之
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] 微細加工培養デバイスを用いたヒト末梢神経系のin vitro再構成2015
- Author(s)
  高山祐三, 木田泰之
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド(兵庫）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] 神経インターフェース技術に基づくインスリン分泌制御手法の開発とデバイス化2015
- Author(s)
  高山祐三、櫛笥博子、渋谷陽一郎、中須麻子、木田泰之
- Organizer
  第13回産総研・産技連LS-BT合同研究発表会
- Place of Presentation
  産業技術総合研究所、つくば
- Year and Date
  2015-02-03
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] Constructing in vitro networks between peripheral neurons and insulin-producing cells using microfabricated devices2015
- Author(s)
  Yuzo Takayama, Yasuyuki S. Kida
- Organizer
  Keystone Symposia, Kyoto, Japan
- Place of Presentation
  Westin Miyako Kyoto（京都府京都市）
- Year and Date
  2015-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15649
[Presentation] Constructing in vitro networks between peripheral neurons and insulin-producing cells using microfabricated devices2015
- Author(s)
  Yuzo Takayama, Yasuyuki S. Kida
- Organizer
  Keystone Symposia; Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies
- Place of Presentation
  ウェスティン都ホテル京都（京都）
- Year and Date
  2015-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] 微細加工培養デバイスを用いたヒト末梢神経系のin vitro再構成2015
- Author(s)
  高山　祐三, 木田　泰之
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15649
[Presentation] Brief Exposure to Small Molecules Allows Conversion of Fibroblasts into Neurons2014
- Author(s)
  高山祐三、櫛笥博子、渋谷陽一郎、中須麻子、木田泰之
- Organizer
  The 9th FENS forum of European Neuroscience
- Place of Presentation
  MiCo - Milano Congressi, Milan, Italy
- Year and Date
  2014-07-08
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] 精密工学技術に基づくin vitro神経回路活動の計測と制御2014
- Author(s)
  高山祐三、鈴木隆文、満渕邦彦、神保泰彦
- Organizer
  第53回日本生体医工学会大会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2014-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-26702015
[Presentation] 脂肪由来細胞からの神経系細胞の誘導
- Author(s)
  櫛笥博子, 高山祐三, 渋谷陽一郎, 中須麻子, 木田泰之
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25882056
[Presentation] 遺伝子導入による幹細胞のtenocyteへの分化誘導法開発およびモデルマウスにおける損傷腱再生迅速化への応用
- Author(s)
  渋谷陽一郎, 木田泰之, 高山祐三, 櫛笥博子, 関堂充
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25882056
[Presentation] 神経インターフェース技術に基づくインスリン分泌制御手法の開発とデバイス化
- Author(s)
  高山祐三, 木田泰之
- Organizer
  第13回産総研・産技連LS-BT合同研究発表会
- Place of Presentation
  産業技術総合研究所（茨城県）
- Data Source
  KAKENHI-PROJECT-25882056
[Presentation] 低分子化合物による線維芽細胞からの神経細胞ダイレクトリプログラミング
- Author(s)
  高山祐三, 櫛笥博子, 渋谷陽一郎, 中須麻子, 木田泰之
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25882056

1. Sekido Mitsuru (40372255)

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2. Shimba Kenta (80792655)

# of Collaborated Projects: 1 results

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3. 足立孝二 (70572569)

# of Collaborated Projects: 1 results

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4. 佐々木薫 (10536220)

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5. 木田泰之 (20396526)

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# of Collaborated Products: 3 results
6. 降幡知巳 (80401008)

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7. 枡田大生 (10722936)

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8. 森尾花恵 (70908524)

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9. 小島伸彦 (90342956)

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10. 森宣仁 (70806215)

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11. 渋谷陽一郎 (50783883)

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12. 冨田峻介 (50726817)

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13. JINBO Yasuhiko

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# of Collaborated Products: 1 results

Takayama Yuzo 高山 祐三

Research Projects

Research Products

Co-Researchers

Creation of 3D tissue culture system integrated with blood vessels and autonomic nerves

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of an in vitro blood vessel model that reproduces the hypertension state and its application to assay systemsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In Vitro Construction of Human Sweat Gland FunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト脳マイクロパソフィジオロジカルシステムズ：脳疾患の生体模倣と創薬研究への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of an On-Chip Cardiomyocyte Model incorporated with Autonomic NeuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studying Intracellular Mechanisms of Pain Information Generation by High-Resolution Electrical Measurement

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reconstruction of sympathetic neuron-vascular interactions in vitro and its applicationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Introduction of some kind of artificial axon to peripheral nerve repair

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Production of pancreatic beta cells/neurons in the autonomic nervous system and neural interface applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経インターフェース技術に基づいたインスリン分泌制御手法の開発とデバイス化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臓器チップの技術と開発動向2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 臓器チップの技術と開発動向2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Deciphering the Molecular Mechanisms of Autonomic Nervous System Neuron Induction through Integrative Bioinformatics Analysis2023

Author(s)

Journal Title

DOI

Takayama Yuzo 高山祐三