Muroi Atsushi 室井敦

Researcher Number	60609402
Other IDs
Affiliation (based on the past Project Information) *help	2022: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 技師・研究員 2016 – 2020: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 技師・研究員 2015: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 研究員 2014: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, その他
Review Section/Research Field	Principal Investigator Basic Section 90130:Medical systems-related / Tumor therapeutics / System genome science Except Principal Investigator Complex systems
Keywords	Principal Investigator 大腸がん / RPPA / 逆相タンパク質アレイ / バイオバンク / 癌 / 分子標的薬 / 細胞死 / 分子標的治療薬 / 卵巣がん / 無細胞タンパク質合成 … More / ウイルス / 宿主因子 / プロテアーゼ / C型肝炎ウイルス … More Except Principal Investigator 生体機能利用 / 癌 / 発生・分化 / プロテオーム / 細胞・組織 / 生体組織の構築と破綻 / 時系列画像データ / 多次元時系列データ / 逆相蛋白質アレイ（RPPA) / 間葉上皮移行(MET) / 上皮間葉移行（EMT） / 逆走蛋白質アレイ / 数理腫瘍学 / 上皮細胞 / 混合正規分布 / 層別化解析 / 数理モデル、 / 逆相タンパク質アレイ / プロテオミクス / がん / チロシンキナーゼ受容体 / RPPA / シミュレーション / 上皮間葉転換（EMT） / 層化解析 / 数理モデル、シミュレーション / 上皮組織 / EMT / 受容体チロシンキナーゼ / 悪性化進展シグナル / 肝がん / 上皮間葉転換 / 肝がん幹細胞 / 生物統計 / 悪性化進展 / 数理シミュレーション / 数理モデル / 逆相タンパク質アレイ（RPPA） / 細胞シグナル / 幹細胞性 / 肝細胞がん Less

バイオバンクの効果的な利用に向けた品質予測法の開発Principal Investigator
- Principal Investigator
  
  室井敦
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Kanagawa Cancer Center Research Institute
Analysis of the molecular mechanism for formation and breakdown of biotissues by mathematical modeling
- Principal Investigator
  
  Koshikawa Naohiko
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Institute of Technology
  Kanagawa Cancer Center Research Institute
Analysis of a novel PACMA compound as a candidate drug for ovarian cancerPrincipal Investigator
- Principal Investigator
  
  Muroi Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kanagawa Cancer Center Research Institute
Comprehensive screening of novel host proteins cleaved by HCV proteasePrincipal Investigator
- Principal Investigator
  
  Muroi Atsushi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  System genome science
- Research Institution
  Kanagawa Cancer Center Research Institute

All 2021 2020 2019

All Journal Article Presentation Book

[Book] 膜タンパク質工学ハンドブック2020
- Author(s)
  室井　敦、星野大輔、清木元治、越川直彦
- Total Pages
  7
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PLANNED-17H06329
[Journal Article] Expression of Cancer Stem Cell Markers EpCAM and CD90 Is Correlated with Anti- and Pro-Oncogenic EphA2 Signaling in Hepatocellular Carcinoma2021
- Author(s)
  Asakura Nobuhiko、Nakamura Naotoshi、Muroi Atsushi、Nojima Yosui、Yamashita Taro、Kaneko Shuichi、Ikeda Kazuki、Koshikawa Naohiko、Suzuki Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 16 Pages: 8652-8652
- DOI
  10.3390/ijms22168652
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05422, KAKENHI-PLANNED-16H06576, KAKENHI-PROJECT-20K15422, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-21K09840
[Journal Article] 肝細胞がんのシグナル伝達と生物統計による層別化2021
- Author(s)
  朝倉暢彦、室井　敦、越川直彦、鈴木　貴
- Journal Title
  
  Precision medicine
  
  Volume: 13 Pages: 1224-1230
- Data Source
  KAKENHI-PLANNED-17H06329
[Journal Article] Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient2020
- Author(s)
  Osumi Hiroki、Muroi Atsushi、Sakahara Mizuho、Kawachi Hiroshi、Okamoto Takuya、Natsume Yasuko、Yamanaka Hitomi、Takano Hiroshi、Kusama Daisuke、Shinozaki Eiji、Ooki Akira、Yamaguchi Kensei、Ueno Masashi、Takeuchi Kengo、Noda Tetsuo、Nagayama Satoshi、Koshikawa Naohiko、Yao Ryoji
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 17455-17455
- DOI
  10.1038/s41598-020-74530-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-19K22570, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329
[Journal Article] Utility of a reverse phase protein array to evaluate multiple biomarkers in diffuse large B‐cell lymphoma2019
- Author(s)
  Suzuki M、Muroi A、Nojima M、Numata A、Takasaki H、Sakai R、Yokose T、Miyagi Y、Koshikawa N.
- Journal Title
  
  Proteomics Clinical Applications
  
  Volume: 14 Issue: 1 Pages: 1900091-1900091
- DOI
  10.1002/prca.201900091
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027
[Presentation] がん幹細胞マーカーによる肝細胞がんの分類とEphA2シグナル伝達2021
- Author(s)
  朝倉暢彦、室井敦、中村直俊、野島陽水、越川直彦、鈴木貴
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] EphA2およびEGFRを介した肝細胞がん進展の数理モデリング2021
- Author(s)
  中村直俊、室井敦、朝倉暢彦、野島陽水、榎本将士、鈴木貴、越川直彦
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] Biostatistical analysis for malignant signaling pathways of hepatocellular carcinoma.2020
- Author(s)
  Koshikawa, N, Muroi A, Asakura N, Enomoto M, Ishiwata M, Suzuki T
- Organizer
  5th Core to Core Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] びまん性大細胞B細胞性リンパ腫における新規診断補助ツールとしての逆相蛋白質アレイの有用性について2019
- Author(s)
  鈴木理樹、室井敦、野島寛、酒井リカ、横瀬智之、宮城洋平、越川直彦
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 逆相蛋白質アレイおよび数理モデルを用いた肝細胞がん悪性化制御シグナルの解析2019
- Author(s)
  室井敦、榎本将士、朝倉暢彦、森達樹、星野大輔、石渡道徳、鈴木貴、越川直彦
- Organizer
  第19回日本蛋白質化学学会年会、第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 数理モデルと逆相蛋白質アレイデータによる肝細胞がん悪性化シグナル経路の解析2019
- Author(s)
  鈴木貴、榎本将士、朝倉暢彦、室井敦、越川直彦
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 数理モデルを用いたがんの悪性化進展制御の解明、第92回日本生化学会大会2019
- Author(s)
  室井敦、榎本将士、森達樹、石渡道徳、星野大輔、鈴木貴、越川直彦
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329

1. Koshikawa Naohiko (70334282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 宮城洋平 (00254194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 石渡通徳 (30350458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 中村直俊 (30554472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 星野大輔 (30571434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 朝倉暢彦 (70308584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 板野景子 (00608416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Yamada Roppei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Sawasaki Tatsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 八尾良司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Muroi Atsushi 室井 敦

Research Projects

Research Products

Co-Researchers

バイオバンクの効果的な利用に向けた品質予測法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the molecular mechanism for formation and breakdown of biotissues by mathematical modeling

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of a novel PACMA compound as a candidate drug for ovarian cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive screening of novel host proteins cleaved by HCV proteasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 膜タンパク質工学ハンドブック2020

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Expression of Cancer Stem Cell Markers EpCAM and CD90 Is Correlated with Anti- and Pro-Oncogenic EphA2 Signaling in Hepatocellular Carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肝細胞がんのシグナル伝達と生物統計による層別化2021

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Utility of a reverse phase protein array to evaluate multiple biomarkers in diffuse large B‐cell lymphoma2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] がん幹細胞マーカーによる肝細胞がんの分類とEphA2シグナル伝達2021

Author(s)

Organizer

Data Source

[Presentation] EphA2およびEGFRを介した肝細胞がん進展の数理モデリング2021

Author(s)

Organizer

Data Source

[Presentation] Biostatistical analysis for malignant signaling pathways of hepatocellular carcinoma.2020

Author(s)

Organizer

Data Source

[Presentation] びまん性大細胞B細胞性リンパ腫における新規診断補助ツールとしての逆相蛋白質アレイの有用性について2019

Author(s)

Organizer

Data Source

[Presentation] 逆相蛋白質アレイおよび数理モデルを用いた肝細胞がん悪性化制御シグナルの解析2019

Author(s)

Organizer

Data Source

[Presentation] 数理モデルと逆相蛋白質アレイデータによる肝細胞がん悪性化シグナル経路の解析2019

Author(s)

Organizer

Data Source

[Presentation] 数理モデルを用いたがんの悪性化進展制御の解明、第92回 日本生化学会大会2019

Author(s)

Organizer

Data Source

Muroi Atsushi 室井敦

[Presentation] 数理モデルを用いたがんの悪性化進展制御の解明、第92回日本生化学会大会2019