Lee Youngae 李英愛

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LEE YOUNGAE 李英愛

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Researcher Number	60610681
Affiliation (based on the past Project Information) *help	2016 – 2019: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤) 2013: 大阪大学, 免疫学フロンティア研究センター, 特任研究員(常勤) 2013: 大阪大学, 免疫学フロンテイア研究センター, 特任研究員(常勤) 2012: 大阪大学, 学内共同利用施設等, 研究員
Review Section/Research Field	Principal Investigator Immunology / Basic Section 42020:Veterinary medical science-related
Keywords	Principal Investigator トキソプラズマ / インターフェロン / 人畜共通感染症 / 寄生胞 / IFN誘導性GTPase / Pphospholipid / Ubiquitination / Toxoplasma gondii / Irgb6 / 獲得免疫系 … More / Ubiquitin / Toxoplasma / IFN-gamma / Nbr1 / NDP52 / p62 / 獲得免疫 / アダプター / オートファジー / マスト細胞 / 細胞分化 / マスト細胞プロテアーゼ / 小腸 / マスト細胞前駆体 / 自然リンパ系細胞（ILC / Mast cell progenitors / α-defensins / Small intestine / Mast cells / Innate lymphoid cells / DEFAs / IL-17F / IL-22 Less

トキソプラズマ原虫に対する宿主免疫系におけるIRGB6の役割の解明Principal Investigator
- Principal Investigator
  
  李英愛
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka University
Role of p62-related autophagy adaptor proteins in anti-microbial host defensePrincipal Investigator
- Principal Investigator
  
  Lee Youngae
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Identification of functional relationship between the ILCs and the mast cells in the small intestinePrincipal Investigator
- Principal Investigator
  
  LEE YOUNGAE
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University

All 2019 2018 2017 2014 2013 2012

All Journal Article Presentation

[Journal Article] Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense.2019
- Author(s)
  Lee, Y., Yamada, H., Pradipta, A., Ma, J.S., Okamoto, M., Nagaoka, H., Takashima, E., Standley, D.M., Sasai, M., Takei, K., Yamamoto, M.
- Journal Title
  
  Life Science Alliance
  
  Volume: 3 Issue: 1 Pages: 000-000
- DOI
  10.26508/lsa.201900549
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07084, KAKENHI-PROJECT-18KK0226, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-18H02430, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-19H03225, KAKENHI-PROJECT-17K08808, KAKENHI-PROJECT-18K05970, KAKENHI-PROJECT-18K15135, KAKENHI-PUBLICLY-19H04809
[Journal Article] Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells2018
- Author(s)
  Bando Hironori、Sakaguchi Naoya、Lee Youngae、Pradipta Ariel、Ma Ji Su、Tanaka Shun、Lai De-Hua、Liu Jianfa、Lun Zhao-Rong、Nishikawa Yoshifumi、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 2073-2073
- DOI
  10.3389/fimmu.2018.02073
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05970, KAKENHI-PROJECT-18K15135, KAKENHI-PROJECT-18KK0226, KAKENHI-PUBLICLY-17H05507, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-17K19538, KAKENHI-PROJECT-17K19556, KAKENHI-PROJECT-17K15677, KAKENHI-PROJECT-15H05275
[Journal Article] Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response2018
- Author(s)
  Bando Hironori、Lee Youngae、Sakaguchi Naoya、Pradipta Ariel、Ma Ji Su、Tanaka Shun、Cai Yihong、Liu Jianfa、Shen Jilong、Nishikawa Yoshifumi、Sasai Miwa、Yamamoto Masahiro
- Journal Title
  
  mBio
  
  Volume: 9 Issue: 5 Pages: 5-5
- DOI
  10.1128/mbio.01738-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05970, KAKENHI-PROJECT-18K15135, KAKENHI-PROJECT-18KK0226, KAKENHI-PUBLICLY-17H05507, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-17K19538, KAKENHI-PROJECT-17K19556, KAKENHI-PROJECT-17K15677, KAKENHI-PROJECT-15H05275
[Journal Article] Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense2017
- Author(s)
  Sasai Miwa、Sakaguchi Naoya、Ma Ji Su、Nakamura Shuhei、Kawabata Tsuyoshi、Bando Hironori、Lee Youngae、Saitoh Tatsuya、Akira Shizuo、Iwasaki Akiko、Standley Daron M、Yoshimori Tamotsu、Yamamoto Masahiro
- Journal Title
  
  Nature Immunology
  
  Volume: 18 Issue: 8 Pages: 899-910
- DOI
  10.1038/ni.3767
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19556, KAKENHI-PROJECT-26713005, KAKENHI-PUBLICLY-17H05507, KAKENHI-PUBLICLY-17H05533, KAKENHI-PUBLICLY-17H06009, KAKENHI-PLANNED-17H06415, KAKENHI-PLANNED-25111002, KAKENHI-PROJECT-15H04745, KAKENHI-PROJECT-17H05064, KAKENHI-PROJECT-16K19116, KAKENHI-PROJECT-16K19153
[Journal Article] Role of Mouse and Human Autophagy Proteins in IFN-γ-Induced Cell-Autonomous Responses against Thxoplasma gondii2014
- Author(s)
  Jun Ohshima, Youngae Lee, Miwa Sasai, Tatsuya Saitoh, Ji Su Ma, Naganori Kamiyama, Yoshiharu Matsuura, Suh Pann-Ghill, Mikako Hayashi, Shigeyuki Ebisu, Kiyoshi Takeda, Shizuo Akira, and Masahiro Yamamoto.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 192(7) Issue: 7 Pages: 3328-35
- DOI
  10.4049/jimmunol.1302822
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J01218, KAKENHI-PROJECT-23689029, KAKENHI-PROJECT-24790474, KAKENHI-PROJECT-24890106, KAKENHI-PUBLICLY-25117717, KAKENHI-PROJECT-25670027, KAKENHI-PUBLICLY-26111514, KAKENHI-PROJECT-26713005, KAKENHI-PROJECT-26860189
[Journal Article] Intestinal Lin-c-Kit+NKp46-CD4- Population Strongly Produces IL-22 upon IL-1β Stimulation2013
- Author(s)
  Youngae Lee, Yutaro Kumagai, Min Seong Jang, Jung-Hwan Kim, Bo-Gie Yang, Eun-Jung Lee, You-Me Kim, Shizuo Akira, and Myoung Ho Jang
- Journal Title
  
  The Journal of Immunology
  
  Volume: 190 Issue: 10 Pages: 5296-5305
- DOI
  10.4049/jimmunol.1201452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790474
[Journal Article] Journal of Dermatological Science2012
- Author(s)
  Hee Jin Byun, Kwang Hyun Cho, Hee Chul Eun, Min-Jung Lee, Youngae Lee, Serah Lee, Jin Ho Chung
- Journal Title
  
  Lipid ingredients in moisturizers can modulate skin responses to UV in barrier-disrupted human skin in vivo.
  
  Volume: 65 Issue: 2 Pages: 110-117
- DOI
  10.1016/j.jdermsci.2011.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790474
[Presentation] An effector IRG is a critical factor mediating interferon-g-induced ubiquitin decoration of Toxoplasma gondii parasitophorous vacuoles2019
- Author(s)
  Youngae Lee
- Organizer
  Parasite-Immunology conference
- Data Source
  KAKENHI-PROJECT-18K05970
[Presentation] An effector IRG is a critical factor mediating interferon-γ-induced ubiquitin decoration of Toxoplasma gondii parasitophorous vacuoles2018
- Author(s)
  Youngae Lee
- Organizer
  Forum Cheju 19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19153
[Presentation] Intestinal Lin-c-Kit+NKp46-CD4- population highly produces IL-22 upon IL-1β stimulation2013
- Author(s)
  Youngae Lee, Yutaro Kumagai, Shizuo Akira, and Myoung Ho Jang
- Organizer
  AAI
- Place of Presentation
  Honolulu, Hawaii
- Data Source
  KAKENHI-PROJECT-24790474
[Presentation] Intestinal Lin^-c-Kit^+NKp46^-CD4^ - population highly produces IL-22 upon IL-1βstimulation2013
- Author(s)
  Y Lee, Y Kumagai, MS Jang, JH Kim, BG Yang, S Akira, and MH Jang
- Organizer
  The American Association of Immunologists (AAI)
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24790474
[Presentation] Intestinal mast cell progenitors function as innate lymphoid cells2012
- Author(s)
  Y Lee, Y Kumagai, S Akira, and MH Jang
- Organizer
  The American Association of Immunologists (AAI)
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24790474
[Presentation] Intestinal mast cell progenitors function as innate lymphoid cells.2012
- Author(s)
  Youngae Lee
- Organizer
  Immunology 2012, AAI Annual meeting
- Place of Presentation
  Hynes Convention Center (Boston, Massachusetts, USA)
- Data Source
  KAKENHI-PROJECT-24790474

1. Sasai Miwa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 竹居孝二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山田浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 山本雅裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Lee Youngae 李 英愛

LEE YOUNGAE 李 英愛

Research Projects

Research Products

Co-Researchers

トキソプラズマ原虫に対する宿主免疫系におけるIRGB6の役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of p62-related autophagy adaptor proteins in anti-microbial host defensePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of functional relationship between the ILCs and the mast cells in the small intestinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Initial phospholipid-dependent Irgb6 targeting to Toxoplasma gondii vacuoles mediates host defense.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Mouse and Human Autophagy Proteins in IFN-γ-Induced Cell-Autonomous Responses against Thxoplasma gondii2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intestinal Lin-c-Kit+NKp46-CD4- Population Strongly Produces IL-22 upon IL-1β Stimulation2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Journal of Dermatological Science2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] An effector IRG is a critical factor mediating interferon-g-induced ubiquitin decoration of Toxoplasma gondii parasitophorous vacuoles2019

Author(s)

Organizer

Data Source

[Presentation] An effector IRG is a critical factor mediating interferon-γ-induced ubiquitin decoration of Toxoplasma gondii parasitophorous vacuoles2018

Author(s)

Organizer

Data Source

[Presentation] Intestinal Lin-c-Kit+NKp46-CD4- population highly produces IL-22 upon IL-1β stimulation2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Intestinal Lin^-c-Kit^+NKp46^-CD4^ - population highly produces IL-22 upon IL-1βstimulation2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Intestinal mast cell progenitors function as innate lymphoid cells2012

Author(s)

Organizer

Place of Presentation

Lee Youngae 李英愛

LEE YOUNGAE 李英愛