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kikuchi hidetomo  菊地 秀与

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菊地 秀与  キクチ ヒデトモ

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Researcher Number 60614055
Other IDs
Affiliation (Current) 2025: 城西大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 城西大学, 薬学部, 准教授
2016 – 2018: 城西大学, 薬学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Except Principal Investigator
Basic Section 47060:Clinical pharmacy-related / Drug development chemistry
Keywords
Principal Investigator
ヒト骨髄系白血病細胞株 / アポトーシス / RXRアゴニス / レチノイドX受容体 / ジヒドロピリミジン誘導体
Except Principal Investigator
Antitumor activity / Cell differentiation / Transporter / Leukemic cells / Darinaparsin … More / Combination therapy / Glioblastoma / Bufadienolides / Arsenic compound / G2/Mアレスト / オートファジー / ガンマブフォタリン / ブファジエノラ イド / DNAダメージ / Notchシグナリング / 細胞周期 / 細胞死 / ブファジェノライド / ヒ素化合物 / 膠芽腫 / 細胞・組織 / 薬理学 / 生理活性 / 有機化学 / 薬学 / RXR / RAR / ベキサロテン / レチノイン酸 / タミバロテン / レチノイド / ジヒドロピリミジン Less
  • Research Projects

    (4 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (11 People)
  •  Fundamental research of antitumor activity of darinaparsin, a novel organic arsenical, against leukemic cells

    • Principal Investigator
      袁 博
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Josai University
  •  RXRを分子標的としたジヒドロピリミジン誘導体の抗悪性腫瘍薬への基礎的研究Principal Investigator

    • Principal Investigator
      菊地 秀与
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Josai University
  •  Fundamental research of antitumor activity of arsenic compound in combination with active bufadienolide compounds against glioblastoma cells

    • Principal Investigator
      袁 博
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Josai University
  •  Development of novel dihydropyrimidine retinoids for medicinal chemistry and drug dicovery

    • Principal Investigator
      Nishimura Yoshio
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Yasuda Women's University

All 2023 2022 2021 2019

All Journal Article Presentation

  • [Journal Article] Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells2023

    • Author(s)
      Yuan Bo、Kikuchi Hidetomo、Li Jingmei、Kawabata Atsushi、Yao Kozo、Takagi Norio、Okazaki Mari
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 3 Pages: 2282-2282

    • DOI

      10.3390/ijms24032282

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Journal Article] Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-872022

    • Author(s)
      Yuan Bo、Li Jingmei、Miyashita Shin-Ich、Kikuchi Hidetomo、Xuan Meiyan、Matsuzaki Hirokazu、Iwata Naohiro、Kamiuchi Shinya、Sunaga Katsuyoshi、Sakamoto Takeshi、Hibino Yasuhide、Okazaki Mari
    • Journal Title

      Molecules

      Volume: 27 Issue: 19 Pages: 6577-6577

    • DOI

      10.3390/molecules27196577

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Presentation] ヒト膠芽腫細胞U-87におけるAsIIIとブファジエノライドの併用による殺細胞効果の増強2023

    • Author(s)
      袁 博、李 ショウ美、宮下 振一、菊地 秀与、玄 美燕、松﨑 広和、岩田 直洋、神内 伸也、須永 克佳、坂本 武史、日比野 康英、岡﨑 真理
    • Organizer
      日本薬学会 第143年会
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Presentation] AsIIIとブファジエノライド化合物のヒト膠芽腫細胞U-87に対する細胞毒性における併用効果2022

    • Author(s)
      李 ショウ美、袁 博、玄 美燕、菊地 秀与、須永 克佳、神内 伸也、日比野 康英、松﨑 広和、岡﨑 真理
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Presentation] In vitroおよびin vivoにおけるAsIIIとブファジエノライド化合物のヒト膠芽腫細胞U-87に対する抗腫瘍活性2022

    • Author(s)
      李 ショウ美、、袁 博、玄 美燕、菊地 秀与、須永 克佳、岩田 直洋、神内 伸也、日比野 康英、松﨑 広和、岡﨑 真理
    • Organizer
      日本薬学会 第142年会
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Presentation] Cytocidal effect of bioactive natural products and its novel derivatives against2021

    • Author(s)
      李 ショウ美、袁 博、玄 美燕、髙山 淳、菊地 秀与、坂本 武史、須永 克佳、神内 伸也、日比野 康英、松﨑 広和、岡﨑 真理
    • Organizer
      日本薬学会 第141年会日本薬学会 第141年会
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Presentation] Antitumor mechanisms of arsenic compounds and its clinical application2021

    • Author(s)
      Bo Yuan, Hidetomo Kikuchi, Norio Takagi, Mari Okazaki
    • Organizer
      The 9th World Integrative Medicine Congress (WIMCO2021)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Presentation] Clinical application of arsenic compounds and the mechanisms underlying their anti-tumor activity2021

    • Author(s)
      Bo Yuan, Hidetomo Kikuchi, Norio Takagi, Mari Okazaki
    • Organizer
      The First Academic Conference of Chinese and Western Integrative Medicine Group, Hematology Branch, Chinese Medical Association
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07136
  • [Presentation] HL-60細胞に対する新規dihydropyrimidine誘導体の細胞毒性誘導2019

    • Author(s)
      菊地 秀与、西村 良夫、久保 貴紀、袁 博、須永 克佳、日比野 康英、長 秀連
    • Organizer
      日本薬学会 第139年会
    • Data Source
      KAKENHI-PROJECT-16K08335
  • 1.  袁 博 (10328552)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 2.  Nishimura Yoshio (60431516)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  岡崎 真理 (50272901)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  玄 美燕 (50711751)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 5.  宮下 振一 (60614766)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  松崎 広和 (80582238)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  久保 貴紀 (90435751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  梨本 正之 (30228069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  岩田 直洋 (50552759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  新井 理絵 (80909507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Cho Hidetsura
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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