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EGUCHI JUN  江口 潤

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Eguchi Jun  江口 潤

EGUCHI Jun  江口 潤

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Researcher Number 60616366
Other IDs
Affiliation (Current) 2025: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2022: 岡山大学, 医歯薬学域, 准教授
2020: 岡山大学, 医歯薬学総合研究科, 准教授
2016 – 2018: 岡山大学, 大学病院, 講師
2012 – 2015: 岡山大学, 大学病院, 助教
2012: 岡山大学, 岡山大学病院, 助教
2011: 岡山大学, 医学部, 客員研究員
Review Section/Research Field
Principal Investigator
Metabolomics / Basic Section 54040:Metabolism and endocrinology-related
Keywords
Principal Investigator
インスリン抵抗性 / メタボリックシンドローム / 脂肪細胞 / 脂肪組織 / メタボリック症候群 / 肥満サルコペニア / 肥満 / 糖尿病 / 肥満症 / マクロファージ / IRF4 / 慢性炎症
  • Research Projects

    (4 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (8 People)
  •  Identification of a novel protein that regulates adipose tissue dysfunction and its pathophysiological significancePrincipal Investigator

    • Principal Investigator
      Eguchi Jun
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Okayama University
  •  Functional roles of proline/arginine-rich end leucine-rich repeat protein (PRELP) in adipocytesPrincipal Investigator

    • Principal Investigator
      Eguchi Jun
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Okayama University
  •  Identification and characterization of a novel protein that regulates adipogenesis and myogenesisPrincipal Investigator

    • Principal Investigator
      EGUCHI JUN
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Okayama University
  •  A novel transcriptional pathway of chronic inflammation in metabolic syndromePrincipal Investigator

    • Principal Investigator
      EGUCHI Jun
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Metabolomics
    • Research Institution
      Okayama University

All 2022 2021 2020 2019 2018 2017 2016 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Roles of Transmembrane Protein 97 (TMEM97) in Adipose Tissue and Skeletal Muscle2022

    • Author(s)
      Tenta M, Eguchi J, Wada J.
    • Journal Title

      Acta Medica Okayama

      Volume: 76 Issue: 3 Pages: 235-245

    • DOI

      10.18926/AMO/63717

    • URL

      https://ousar.lib.okayama-u.ac.jp/63717

    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08908
  • [Journal Article] Circulating GPIHBP1 levels and microvascular complications in patients with type 2 diabetes: A cross-sectional study.2022

    • Author(s)
      Kurooka N, Eguchi J, Murakami K, Kamei S, Kikutsuji T, Sasaki S, Seki A, Yamaguchi S, Nojima I, Watanabe M, Higuchi C, Katayama A, Uchida HA, Nakatsuka A, Shikata K, Wada J.
    • Journal Title

      J Clin Lipidol.

      Volume: 22 Issue: 2 Pages: 21-26

    • DOI

      10.1016/j.jacl.2022.01.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-20K08908, KAKENHI-PROJECT-20K08608
  • [Journal Article] Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4.2022

    • Author(s)
      Yamaguchi S, Zhang D, Katayama A, Kurooka N, Sugawara R, Albuayjan HHH, Nakatsuka A, Eguchi J, Wada J.
    • Journal Title

      Front Endocrinol (Lausanne).

      Volume: 12 Pages: 750261-750261

    • DOI

      10.3389/fendo.2021.750261

    • NAID

      120007188342

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-20K08908, KAKENHI-PROJECT-20K08608
  • [Journal Article] The Association of Postprandial Triglyceride Variability with Renal Dysfunction and Microalbuminuria in Patients with Type 2 Diabetic Mellitus: A Retrospective and Observational Study2022

    • Author(s)
      Matsuoka-Uchiyama Natsumi、Uchida Haruhito A.、Okamoto Shugo、Onishi Yasuhiro、Katayama Katsuyoshi、Tsuchida-Nishiwaki Mariko、Takeuchi Hidemi、Takemoto Rika、Hada Yoshiko、Umebayashi Ryoko、Kurooka Naoko、Tsuji Kenji、Eguchi Jun、Nakajima Hirofumi、Shikata Kenichi、Wada Jun
    • Journal Title

      Journal of Diabetes Research

      Volume: 2022 Pages: 1-12

    • DOI

      10.1155/2022/3157841

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08908
  • [Journal Article] A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease2021

    • Author(s)
      Nakatsuka A, Yamaguchi S, Eguchi J, Kakuta S, Iwakura Y, Sugiyama H, Wada J.
    • Journal Title

      Commun Biol .

      Volume: 4 Issue: 1 Pages: 373-373

    • DOI

      10.1038/s42003-021-01902-y

    • NAID

      120007004153

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08608, KAKENHI-PROJECT-20K08908, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-19K17984, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K08679
  • [Journal Article] Longitudinal observation of insulin secretory ability before and after the onset of immune checkpoint inhibitor‐induced diabetes mellitus: A report of two cases2021

    • Author(s)
      Fujiwara Noriko、Watanabe Mayu、Katayama Akihiro、Noda Yohei、Eguchi Jun、Kataoka Hitomi、Kagawa Shunsuke、Wada Jun
    • Journal Title

      Clinical Case Reports

      Volume: 9 Issue: 9

    • DOI

      10.1002/ccr3.4574

    • NAID

      120007161107

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08908
  • [Journal Article] Upregulation of Mir342 in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control.2021

    • Author(s)
      Zhang D, Yamaguchi S, Zhang X, Yang B, Kurooka N, Sugawara R, Albuayjan HHH, Nakatsuka A, Eguchi J, Hiyama TY, Kamiya A, Wada J.
    • Journal Title

      Front Endocrinol (Lausanne).

      Volume: 12 Pages: 727915-727915

    • DOI

      10.3389/fendo.2021.727915

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-20K08908, KAKENHI-PROJECT-20K08608
  • [Journal Article] Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.2021

    • Author(s)
      Nunoue T, Yamaguchi S, Teshigawara S, Katayama A, Nakatsuka A, Eguchi J, Niki T, Wada J.
    • Journal Title

      Sci Rep.

      Volume: 16 Issue: 1 Pages: 5991-5991

    • DOI

      10.1038/s41598-021-85080-1

    • NAID

      120007004155

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08608, KAKENHI-PROJECT-20K08908, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-19K17984
  • [Journal Article] Dysfunction of CD8 + PD-1 + T cells in type 2 diabetes caused by the impairment of metabolism-immune axis2020

    • Author(s)
      Nojima I, Eikawa S, Tomonobu N, Hada Y, Kajitani N, Teshigawara S, Miyamoto S, Tone A, Uchida HA, Nakatsuka A, Eguchi J, Shikata K, Udono H, Wada J.
    • Journal Title

      Sci Rep.

      Volume: 10 Issue: 1 Pages: 14928-14928

    • DOI

      10.1038/s41598-020-71946-3

    • NAID

      120006891215

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08608, KAKENHI-PROJECT-20K08908, KAKENHI-PROJECT-18H04033, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-17K09698
  • [Journal Article] GPIHBP1 autoantibody syndrome during interferon β1a treatment.2019

    • Author(s)
      Eguchi J, Miyashita K, Fukamachi I, Nakajima K, Murakami M, Kawahara Y, Yamashita T, Ohta Y, Abe K, Nakatsuka A, Mino M, Takase S, Okazaki H, Hegele RA, Ploug M, Hu X, Wada J, Young SG, Beigneux AP.
    • Journal Title

      J Clin Lipidol

      Volume: 13 Issue: 1 Pages: 62-69

    • DOI

      10.1016/j.jacl.2018.10.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09861, KAKENHI-PROJECT-17H04109, KAKENHI-PROJECT-16K09783
  • [Journal Article] Effect of an enhanced recovery after surgery protocol in patients undergoing pancreaticoduodenectomy: A randomized controlled trial.2018

    • Author(s)
      Takagi K, Yoshida R, Yagi T, Umeda Y, Nobuoka D, Kuise T, Hinotsu S, Matsusaki T, Morimatsu H, Eguchi J, Wada J, Senda M, Fujiwara T.
    • Journal Title

      Clinical Nutrition

      Volume: in press Issue: 1 Pages: 174-181

    • DOI

      10.1016/j.clnu.2018.01.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10573, KAKENHI-PROJECT-16K09783
  • [Journal Article] Acquired partial lipoatrophy as graft-versus-host disease and treatment with metreleptin: two case reports.2018

    • Author(s)
      Shibata Y, Nakatsuka A, Eguchi J, Miyamoto S, Masuda Y, Awazawa M, Takaki A, Yoshida R, Yagi T, Wada J.
    • Journal Title

      J Med Case Rep.

      Volume: 12 Issue: 1 Pages: 368-368

    • DOI

      10.1186/s13256-018-1901-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09861, KAKENHI-PROJECT-16K09783
  • [Journal Article] Identification of Novel Urinary Biomarkers for Predicting Renal Prognosis in Patients With Type 2 Diabetes by Glycan Profiling in a Multicenter Prospective Cohort Study: U-CARE Study 1.2018

    • Author(s)
      Mise K, Imamura M, Yamaguchi S, Teshigawara S, Tone A, Uchida HA, Eguchi J, Nakatsuka A, Ogawa D, Yoshida M, Yamada M, Shikata K, Wada J.
    • Journal Title

      Diabetes Care.

      Volume: 41 Issue: 8 Pages: 1765-1775

    • DOI

      10.2337/dc18-0030

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09861, KAKENHI-PROJECT-16K09783, KAKENHI-PROJECT-17K09698
  • [Journal Article] Renal expression of trefoil factor 3 mRNA in association with tubulointerstitial fibrosis in IgA nephropathy2018

    • Author(s)
      Tanaka Keiko、Sugiyama Hitoshi、Yamanari Toshio、Mise Koki、Morinaga Hiroshi、Kitagawa Masashi、Onishi Akifumi、Ogawa-Akiyama Ayu、Tanabe Katsuyuki、Eguchi Jun、Ohmoto Yasukazu、Shikata Kenichi、Wada Jun
    • Journal Title

      Nephrology

      Volume: 23 Issue: 9 Pages: 855-862

    • DOI

      10.1111/nep.13444

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16002, KAKENHI-PROJECT-16K09616, KAKENHI-PROJECT-16K09783, KAKENHI-PROJECT-17K09698
  • [Journal Article] メタボリックシンドロームにおける脂肪組織繊維化の発症分子機構2017

    • Author(s)
      江口 潤
    • Journal Title

      臨床病理

      Volume: 65 Pages: 824-828

    • Data Source
      KAKENHI-PROJECT-16K09783
  • [Journal Article] Antiobesity action of ACAM by modulating the dynamics of cell adhesion and actin polymerization in adipocytes.2016

    • Author(s)
      Murakami K, Eguchi J, Hida K, Nakatsuka A, Katayama A, Sakurai M, Choshi H, Furutani M, Ogawa D, Takei K, Otsuka F, Wada J
    • Journal Title

      Diabetes

      Volume: 65(5) Issue: 5 Pages: 1255-1267

    • DOI

      10.2337/db15-1304

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293218, KAKENHI-PROJECT-26461361, KAKENHI-PROJECT-26461362, KAKENHI-PROJECT-15K09434, KAKENHI-PROJECT-16K09783
  • [Journal Article] IRF3 promotes adipose inflammation and insulin resistance and represses browning.2016

    • Author(s)
      Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED.
    • Journal Title

      J Clin Invest

      Volume: 126 Issue: 8 Pages: 2839-54

    • DOI

      10.1172/jci86080

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09783
  • [Journal Article] Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose-induced oxidative stress in type 1 diabetic mice.2016

    • Author(s)
      Hatanaka T, Ogawa D, Tachibana H, Eguchi J, Inoue T, Yamada H, Takei K, Makino H, Wada J.
    • Journal Title

      Pharmacol Res Perspect.

      Volume: 4(4) Issue: 4

    • DOI

      10.1002/prp2.239

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293218, KAKENHI-PROJECT-16K09783
  • [Journal Article] Interferon Regulatory Factor 4 Regulates Obesity-Induced Inflammation Through Regulation of Adipose Tissue Macrophage Polarization2013

    • Author(s)
      Jun Eguchi, Xingxing Kong, Masafumi Tenta, Xun Wang, Sona Kang and Evan D. Rosen
    • Journal Title

      Diabetes

      Volume: 62 Issue: 10 Pages: 3394-3403

    • DOI

      10.2337/db12-1327

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461354
  • [Journal Article] FOSL2 promotes human adipocyte-specific leptin gene expression2012

    • Author(s)
      Wrann CD, Eguchi J, Bozec A, Xu Z, Mikkelsen T, Gimble J, Nave H, Wagner EF, Ong SE, Rosen ED
    • Journal Title

      Journal Clin Invest

      Volume: 122 Pages: 1010-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Journal Article] RXR antagonism induces G(0)/G(1) cell cycle arrest and ameliorates obesity by up-regulating the p53-p21 pathway in adipocytes.2012

    • Author(s)
      Nakatsuka A, Wada J, Hida K, Hida A,Eguchi J, Teshigawara S, Murakami K, Kanzaki M, Inoue K, Terami T, Katayama A, Ogawa D, Kagechika H, Makino H
    • Journal Title

      J Pathol

      Volume: 226 Pages: 784-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Journal Article] Serum vaspin concentrations are closely related to insulin resistance, and rs77060950 at serpina12 genetically defines distinct group with higher serum levels in japanese population.2012

    • Author(s)
      Teshigawara S, Wada J, Hida K, Nakatsuka A, Eguchi J,Murakami K, Kanzaki M, Inoue K, Terami T, Katayama A, Iseda I, Matsushita Y, Miyatake N, McDonald JF, Hotta K, Makino H
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 97(7) Pages: 1202-7

    • NAID

      120005232486

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Journal Article] Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes.2011

    • Author(s)
      Kanzaki M, Wada J, Sugiyama K, Nakatsuka A, Teshigawara S, Murakami K, Inoue K, Terami T, Katayama A, Eguchi J,Makino H
    • Journal Title

      Endocrinology

      Volume: 153(2) Pages: 612-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] 脂肪組織リモデリングの制御因子の同定と機能解析2017

    • Author(s)
      江口 潤
    • Organizer
      ConBio2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09783
  • [Presentation] 脂肪組織のリモデリングにおけるPRELPの病態生理的意義2017

    • Author(s)
      江口 潤
    • Organizer
      第38回日本肥満学会
    • Data Source
      KAKENHI-PROJECT-16K09783
  • [Presentation] Roles of PRELP in adiocyte biology2017

    • Author(s)
      JUN EGUCHI
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Keystone conference center
    • Year and Date
      2017-01-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09783
  • [Presentation] 脂肪組織のリモデリングにおけるPRELPの病態生理的意義2016

    • Author(s)
      江口 潤
    • Organizer
      第19回アディポサイエンス・シンポジウム
    • Place of Presentation
      千里ライフサイエンスセンサー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09783
  • [Presentation] レプチン遺伝子の発現を制御する新規転写因子の同定2012

    • Author(s)
      江口 潤
    • Organizer
      第33回日本肥満学会 シンポジウム「Adiposcienceの新展開 肥満症の基礎研究」
    • Place of Presentation
      京都
    • Year and Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] 「Roles of IRF4 in adipocyte biology」シンポジウム2011

    • Author(s)
      江口 潤
    • Organizer
      第34回日本分子生物学学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] メタボリック症候群におけるIRF4 の役割2011

    • Author(s)
      江口 潤
    • Organizer
      2011 年度アディポサイエンス研究会 (招待講演)
    • Place of Presentation
      大阪府豊中市
    • Year and Date
      2011-08-20
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] メタボリック症候群におけるIRF4の役割2011

    • Author(s)
      江口潤
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(招待講演)
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] メタボリック症候群におけるマクロファージIRF4の役割2011

    • Author(s)
      江口潤
    • Organizer
      1.第32回日本肥満学会
    • Place of Presentation
      兵庫県淡路市
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] メタボリック症候群におけるマクロファージIRF4の役割2011

    • Author(s)
      江口 潤
    • Organizer
      第32回日本肥満学会
    • Place of Presentation
      兵庫県淡路市
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] メタボリック症候群におけるIRF4の役割2011

    • Author(s)
      江口潤
    • Organizer
      2011年度アディポサイエンス研究会
    • Place of Presentation
      大阪府豊中市(招待講演)
    • Year and Date
      2011-08-20
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] レプチン遺伝子の発現を制御する新規転写因子の同定

    • Author(s)
      江口 潤
    • Organizer
      第33回日本肥満学会
    • Place of Presentation
      京都市
    • Invited
    • Data Source
      KAKENHI-PROJECT-23890116
  • [Presentation] メタボリック症候群におけるマクロファージIRF4の病態生理学的意義

    • Author(s)
      江口 潤
    • Organizer
      第55回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23890116
  • 1.  YAGI Takahito
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  UMEDA Yuzo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  FUJI Tomokazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  MORI Yoshiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  藤原 俊義
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  中司 敦子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 7.  和田 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 8.  田中 景子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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