Suzuki Toshiharu 鈴木俊治

… Alternative Names

SUZUKI Toshiharu 鈴木俊治

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Researcher Number	60618809
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 開拓研究所, 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人理化学研究所, 開拓研究本部, 客員研究員 2018 – 2020: 東京工業大学, 科学技術創成研究院, 特任教授 2016 – 2017: 東京大学, 大学院工学系研究科(工学部), 主幹研究員 2014 – 2015: 東京大学, 工学(系)研究科(研究院), 主幹研究員 2012 – 2013: 東京工業大学, 資源化学研究所, 東工大特別研究員
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Functional biochemistry
Keywords	Principal Investigator F1-ATPase / FoF1-ATP合成酵素 / ATP / ATPase / 結晶構造解析 / 分子モーター / motor protein / 反応機構 / ATP合成酵素 / motor proteins … More / X-ray crystallography / structural biology / FoF1-ATP syntase / crystal structure / X線結晶構造解析 / 顕微鏡一分子観察 / 構造機能相関 / 生体エネルギー変換 / FoF1-ATP synthase / 反応素過程 / human / single molecule analysis Less

X線結晶構造解析を駆使した哺乳類F1の回転力発生機構の解明Principal Investigator
- Principal Investigator
  
  鈴木俊治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Institute of Physical and Chemical Research
Analyses of torque-generation mechanism of F1-ATPase by time-divided X-ray crystallographic studyPrincipal Investigator
- Principal Investigator
  
  Suzuki Toshiharu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Institute of Physical and Chemical Research
  Tokyo Institute of Technology
Analysis of regulatory mechanism of human FoF1-ATP synthasePrincipal Investigator
- Principal Investigator
  
  Suzuki Toshiharu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Analyses of inhibitory effects of Inhibitory factor-1 on human ATP-synthase.Principal Investigator
- Principal Investigator
  
  SUZUKI Toshiharu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
  Tokyo Institute of Technology

All 2019 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 実験医学増刊「構造生命科学で何がわかるのか、何ができるのか」2014
- Author(s)
  鈴木俊治、吉田賢右
- Total Pages
  150
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24570149
[Journal Article] Structure of a Bacterial ATP Synthase2019
- Author(s)
  Gui H, Suzuki T, Rubunstein JL
- Journal Title
  
  Elife
  
  Volume: 8
- DOI
  10.7554/elife.43128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02409
[Journal Article] Perfect chemo-mechanical coupling of FoF1-ATP synthase.2017
- Author(s)
  Soga N, Kimura K, Kinosita, K Jr, Yoshida M and Suzuki T
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 114 Issue: 19 Pages: 4960-4965
- DOI
  10.1073/pnas.1700801114
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07014, KAKENHI-PUBLICLY-17H05717
[Journal Article] Identification of aqueous access residues of the sodium half channel in transmembrane helix 5 of the Fo-a subunit of Propionigenium modestum ATP synthase2017
- Author(s)
 Mitome N, Sato H, Tomiyama T, Shimabukuro K, Matsunishi T, Hamada K and Suzuki T
- Journal Title
 
 Biophysics and Physicobiology
 
 Volume: 14 Issue: 0 Pages: 41-47
- DOI
 10.2142/biophysico.14.0_41
- NAID
 130005449851
- ISSN
 2189-4779
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-15K07014, KAKENHI-PROJECT-16K14771
[Journal Article] Protons Regulate Vesicular Glutamate Transporters through an Allosteric Mechanism.2016
- Author(s)
  Eriksen J, Chang R, McGregor M, Silm K, Suzuki T, Edwards RH
- Journal Title
  
  Neuron
  
  Volume: 90(4) Issue: 4 Pages: 768-780
- DOI
  10.1016/j.neuron.2016.03.026
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07014
[Journal Article] Expression of mammalian mitochondrial F1-ATPase in Escherichia coli depends on two chaperone factors, AF1 and AF2.2016
- Author(s)
  Suzuki T, Iida N, Suzuki J, Watanabe Y, Endo T, Hisabori T and Yoshida M
- Journal Title
  
  FEBS Open Bio
  
  Volume: 6(12) Issue: 12 Pages: 1267-1272
- DOI
  10.1002/2211-5463.12143
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07014, KAKENHI-PROJECT-15H05705
[Journal Article] Structure of a thermophilic F1-ATPase inhibited by an ε-subunit: Deeper insight into the ε-inhibition mechanism.2015
- Author(s)
  Shirakihara Y, Shiratori A, Tanikawa H, Nakasako M, Yoshida M and Suzuki T
- Journal Title
  
  FEBS J
  
  Volume: 282 Issue: 15 Pages: 2895-913
- DOI
  10.1111/febs.13329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07014
[Journal Article] A simple mechanism how F1-ATPase motor rotates with near-perfect chemo-mechanical energy conversion.2015
- Author(s)
  Saita E, Suzuki T, Kinosita K Jr, Yoshida M
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 112 Issue: 31 Pages: 9626-9631
- DOI
  10.1073/pnas.1422885112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07014, KAKENHI-PROJECT-26221102
[Journal Article] Vesicular Glutamate Transporters use flexible anion and cation binding sites for efficient accumulation of neurotransmitter.2014
- Author(s)
  Preobraschenski, J, Zender, JF, Suzuki, T, and Jahn, R
- Journal Title
  
  Neuron
  
  Volume: 84 Issue: 6 Pages: 1287-301
- DOI
  10.1016/j.neuron.2014.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570149
[Journal Article] Chemo-mechanical coupling of human mitochondrial F1-ATPase motor.2014
- Author(s)
  Suzuki T*, Tanaka K, Wakabayashi C, Saita E, Yoshida M
- Journal Title
  
  Nature Chem Biol
  
  Volume: 10 Issue: 11 Pages: 930-936
- DOI
  10.1038/nchembio.1635
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23227006, KAKENHI-PROJECT-24570149
[Journal Article] Evaluation of intra-mitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation2013
- Author(s)
  Kioka H, Kato H, Fujikawa M, Tsukamoto O, Suzuki T, Imamura H, Nakano A, Higo S, Yamazaki S, Matsuzaki T, Tkafuji K, Asanuma H, Asakura M, Minamino T, Shintani Y, Yoshida M, Noji H, Kitakaze M, Komuro I, Asano Y and Takashima S
- Journal Title
  
  PNAS
  
  Volume: 111 Issue: 1 Pages: 273-278
- DOI
  10.1073/pnas.1318547111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-23227006, KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24570149, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790757, KAKENHI-PROJECT-24790917, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-25461119, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26461108
[Presentation] ATP加水分解反応中には何が起きているのか? -X線結晶構造解析による哺乳類F1-ATPaseのcatalytic turnoverの分析-2019
- Author(s)
  鈴木俊治、山下栄樹、馬場清喜、長谷川和也、熊坂崇、平田邦生、遠藤斗志也、吉田賢右、久堀徹
- Organizer
  日本結晶学会令和元年度年会
- Data Source
  KAKENHI-PROJECT-18H02409
[Presentation] タンパク質が力を紡ぎ出す仕組みとは? 近年の構造解析技術が明らかにしたFoF1-ATP合成酵素の回転力発生機構2019
- Author(s)
  鈴木俊治
- Organizer
  理研セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H02409
[Presentation] What happens during ATPase’s turnover? X-ray crystallographic analysis for catalytic turnover of mammalian F1-ATPases2019
- Author(s)
  Toshiharu Suzuki, Eiki Yamashita, Seiki Baba, Kazuya Hasegawa, Kunio Hirata, Takashi Kumasaka, Toshiya Endo, Masasuke Yoshida, Toru Hisabori
- Organizer
  ASCA2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02409
[Presentation] ハイブリッドF1-ATPaseの1分子回転観察2019
- Author(s)
  渡邉亮, 上野博史, 鈴木俊治, 小林稜平, 野地博行
- Organizer
  第57回生物物理学会
- Data Source
  KAKENHI-PROJECT-18H02409
[Presentation] Structural and biophysical analyses of torque generation mechanism of FoF1-ATP synthase2019
- Author(s)
  Toshiharu Suzuki
- Organizer
  第57回生物物理学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02409
[Presentation] F1-ATPaseの構造解析と反応機構の解明2019
- Author(s)
  195.鈴木俊治
- Organizer
  大阪大学蛋白研セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H02409
[Presentation] Structural and biophysical analyses of torque generation mechanism of FoF1-ATPase and F1-ATPase2019
- Author(s)
  Toshiharu Suzuki
- Organizer
  2019 Gordon Research Conference on Bioenergetics: Integration of Structure, Mechanism and Theory of Bioenergy Conversion in Health and Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02409
[Presentation] 角度分割・時分割X線結晶構造解析による、哺乳類F1-ATPaseのリン酸解離駆動の回転力発生機構の解明2017
- Author(s)
  鈴木俊治、平田邦生、山下栄樹、遠藤斗志也、久堀徹、吉田賢右、野地博行
- Organizer
  第6回日本生物物理学会関東支部会
- Place of Presentation
  早稲田大学(東京都)
- Year and Date
  2017-03-13
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] How does F1-ATPase drive rotation? X-ray crystallography and single-molecule studies of mammalian F1-ATPases、2016
- Author(s)
  Toshiharu Suzuki
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] Analyses of rotation and regulatory mechanisms of mammalian F1-ATPase by angle-divided X-ray crystallographic study.2016
- Author(s)
  Toshiharu Suzuki
- Organizer
  Japan Biophysical Society
- Place of Presentation
  茨城県つくば市つくば国際会議場
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] X線結晶構造解析と顕微鏡一分子解析による、哺乳類F1-ATPaseの回転力発生・調節機構の解明2016
- Author(s)
  鈴木俊治
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡県福岡市博多区福岡国際会議場
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] Angle-divided structural analysis of mammalian F1-ATPase:Torque generation and regulatory mechanisms.2016
- Author(s)
  Toshiharu Suzuki
- Organizer
  第54回日本生物物理学会年会(シンポジウム)
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] Determination of the proton pump activity and the H+/ATP ratio of thermophilic Bacillus PS3 FoF1-ATP synthase.2016
- Author(s)
  Naoya Iida, Yuzo Kasuya, Naoki Soga, Toshiharu Suzuki, Taro Uyeda, Masasuke Yoshida, Kazuhiko Kinosita
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] Arginine finger mediated rotation of bovine F1-ATPase driven by phosphate-release.2016
- Author(s)
  Toshiharu Suzuki, Masasuke Yoshida, Toshiya Endo, Toru Hisabori, Hiroyuki Noji
- Organizer
  European Bioenergetics Conference 2016
- Place of Presentation
  Congress centre, Riva del Garda TN, Italia
- Year and Date
  2016-07-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] Arginine finger mediated rotation of bovine F1-ATPase driven by phosphate-release.2016
- Author(s)
  Toshiharu Suzuki
- Organizer
  European Bioenergetics conference 2016
- Place of Presentation
  Riva del Garda (Italia)
- Year and Date
  2016-07-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] Unveiling the chemomechanical coupling of F1 ATPase of Paracoccus denitrificans.2016
- Author(s)
  Mariel Zarco - Zavala, Duncan G G McMillan, Toshiharu Suzuki, Hiroshi Ueno, Francisco Mendoza-Hoffmann, Jose J. Garcia-Trejo, Hiroyuki Noji
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] ResveratrolによるウシF1-ATPaseの回転調節機構の解明2015
- Author(s)
  奥村元、鈴木俊治、吉田賢右、遠藤斗志也、野地博行
- Organizer
  日本生体エネルギー研究会第41回討論会
- Place of Presentation
  東京都文京区東京大学
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] ヒトのエネルギー生産システムはどのように調節されるのか? 生体因子・天然物によるヒト・ウシF1-ATPaseの阻害の分子メカニズム2015
- Author(s)
  鈴木俊治、若林千晃、田中一巳、鈴木純子、野地博行、吉田賢右
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  徳島県徳島市藍場町あわぎんホール
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] 好熱菌由来Bacillus PS3由来FoF1-ATP合成酵素のATP駆動によるH+ポンプ活性の定量2015
- Author(s)
  飯田直也、粕谷有造、曽我直樹、田崎健、鈴木俊治、吉田賢右、木下一彦
- Organizer
  日本生体エネルギー研究会第41回討論会
- Place of Presentation
  東京都文京区東京大学
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] 哺乳類F1-ATPaseのリン酸解離による回転力発生機構2015
- Author(s)
  鈴木俊治、奥村元、吉川祐輔、飯田直也、鈴木純子、木下一彦、渡邊康紀、遠藤斗志也、野地博行、吉田賢右
- Organizer
  日本生体エネルギー研究会第41回討論会
- Place of Presentation
  東京都文京区東京大学
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] 哺乳類F1-ATPaseの回転を介したエネルギー変換の仕組みと、生体内因子・天然物による機能阻害のメカニズム2015
- Author(s)
  鈴木俊治
- Organizer
  BMB2015(生化学会分子生物学会合同年会)のワークショップ(呼吸鎖複合体とATP合成の新描像)
- Place of Presentation
  兵庫県神戸市中央区神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] Na+輸送型FoF1-ATP合成酵素のaサブユニットのイオンチャンネルの解析2015
- Author(s)
  富山泰至、佐藤宏樹、鈴木俊治、松西拓哉、濱田康平、吉田賢右、三留規誉
- Organizer
  日本生体エネルギー研究会第41回討論会
- Place of Presentation
  東京都文京区東京大学
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-15K07014
[Presentation] 生命のATPシステムを作り出すFoF1-ATP合成酵素2014
- Author(s)
  鈴木俊治
- Organizer
  大阪大学医学部講演会
- Place of Presentation
  大阪大学
- Invited
- Data Source
  KAKENHI-PROJECT-24570149
[Presentation] 生命のATPシステムを作り出す、FoF1-ATP合成酵素の分子機構2014
- Author(s)
  鈴木俊治
- Organizer
  東京大学講演会
- Place of Presentation
  東京大学・本郷
- Year and Date
  2014-06-10
- Invited
- Data Source
  KAKENHI-PROJECT-24570149
[Presentation] ヒトF1-ATPaseの一分子解析が明らかにした、バクテリアとは異なったミトコンドリアF1の回転スキーム2013
- Author(s)
  鈴木俊治、田中一巳、若林千晃、古池晶、税田英一郎、木下一彦、吉田賢右
- Organizer
  日本生体エネルギー研究会第39開討論会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24570149
[Presentation] Single molecule analyses of human F1-ATPase revealed distinct rotation scheme of mitochondrial F1 motor.2013
- Author(s)
  Toshiharu Suzuki, Kazumi Tanaka, Chiaki Wakabayashi, Shou Furuike, Eiichiro Saita, Kazuhiko Kinosita, Masasuke Yoshida
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24570149
[Presentation] ヒトF1-ATPaseの回転・制御機構2012
- Author(s)
  鈴木俊治
- Organizer
  分子モーター討論会
- Place of Presentation
  東大・本郷
- Invited
- Data Source
  KAKENHI-PROJECT-24570149
[Presentation] Single-molecule analyses of the rotation and regulation of human F1-ATPase2012
- Author(s)
  Toshiharu Suzuki, Tanaka Kazumi, Chiaki Wakabayashi, Eiichiro Saita, Shou Furuike, Kazuhiko Kinosita Jr, Masasuke Yoshida
- Organizer
  日本生物物理学会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-24570149
[Presentation] ヒトF1-ATPaseの回転と制御の一分子解析2012
- Author(s)
  鈴木俊治、田中一巳、若林千晃、古池晶、税田英一郎、木下一彦、吉田賢右
- Organizer
  日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24570149
[Presentation] Single molecule analyses of human F1-ATPase revealed distinct rotation scheme of mitochondrial F1 motor.
- Author(s)
  Toshiharu Suzuki
- Organizer
  Tokyo ATPase Workshop
- Place of Presentation
  東京大学・本郷
- Year and Date
  2014-06-02 – 2014-06-03
- Invited
- Data Source
  KAKENHI-PROJECT-24570149

1. 吉田賢右

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 野地博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Toshiharu 鈴木 俊治

SUZUKI Toshiharu 鈴木 俊治

Research Projects

Research Products

Co-Researchers

X線結晶構造解析を駆使した哺乳類F1の回転力発生機構の解明Principal Investigator

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Analyses of torque-generation mechanism of F1-ATPase by time-divided X-ray crystallographic studyPrincipal Investigator

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Analysis of regulatory mechanism of human FoF1-ATP synthasePrincipal Investigator

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Analyses of inhibitory effects of Inhibitory factor-1 on human ATP-synthase.Principal Investigator

Principal Investigator

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[Book] 実験医学増刊「構造生命科学で何がわかるのか、何ができるのか」2014

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[Journal Article] Structure of a Bacterial ATP Synthase2019

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[Journal Article] Perfect chemo-mechanical coupling of FoF1-ATP synthase.2017

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[Journal Article] Identification of aqueous access residues of the sodium half channel in transmembrane helix 5 of the F<sub>o</sub>-<i>a</i> subunit of <i>Propionigenium modestum</i> ATP synthase2017

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[Journal Article] Protons Regulate Vesicular Glutamate Transporters through an Allosteric Mechanism.2016

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[Journal Article] Expression of mammalian mitochondrial F1-ATPase in Escherichia coli depends on two chaperone factors, AF1 and AF2.2016

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[Journal Article] Structure of a thermophilic F1-ATPase inhibited by an ε-subunit: Deeper insight into the ε-inhibition mechanism.2015

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[Journal Article] A simple mechanism how F1-ATPase motor rotates with near-perfect chemo-mechanical energy conversion.2015

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[Journal Article] Vesicular Glutamate Transporters use flexible anion and cation binding sites for efficient accumulation of neurotransmitter.2014

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[Journal Article] Chemo-mechanical coupling of human mitochondrial F1-ATPase motor.2014

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Suzuki Toshiharu 鈴木俊治

SUZUKI Toshiharu 鈴木俊治