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Inoue Kazuki  井上 和樹

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KAZUKI INOUE  井上 和樹

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Researcher Number 60623725
Other IDs
Affiliation (based on the past Project Information) *help 2017: 愛媛大学, 学術支援センター, 助教
2012 – 2013: 愛媛大学, 総合科学研究支援センター, 助教
Review Section/Research Field
Principal Investigator
Applied biochemistry
Except Principal Investigator
Orthopaedic surgery
Keywords
Principal Investigator
性差 / Y染色体
Except Principal Investigator
遺伝子改変マウス / 分化 / 運動器 / 軟骨細胞 / DNAメチル化 / Uhrf1 / エピジェネティック制御因子 / ゲノムワイド解析 / 軟骨 / エピジェネティクス
  • Research Projects

    (2 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (9 People)
  •  Investigation of epigenetic therapeutic targets for musculoskeletal diseases

    • Principal Investigator
      Yuuki Imai
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Ehime University
  •  Study of Y chromosome gene in sex differences of skeletal growthPrincipal Investigator

    • Principal Investigator
      KAZUKI INOUE
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied biochemistry
    • Research Institution
      Ehime University

All 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

  • [Journal Article] Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression2017

    • Author(s)
      Yamashita Michiko、Inoue Kazuki、Saeki Noritaka、Ideta-Otsuka Maky、Yanagihara Yuta、Sawada Yuichiro、Sakakibara Iori、Lee Jiwon、Ichikawa Koichi、Kamei Yoshiaki、Iimura Tadahiro、Igarashi Katsuhide、Takada Yasutsugu、Imai Yuuki
    • Journal Title

      Development

      Volume: 145 Issue: 1 Pages: 157412-157412

    • DOI

      10.1242/dev.157412

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19728, KAKENHI-PROJECT-26293392, KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-17H01882, KAKENHI-PROJECT-16K20412
  • [Journal Article] The HIV co-receptor CCR5 regulates osteoclast function.2017

    • Author(s)
      Lee JW, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, Ueha S, Matsushima K, Yamaguchi A, Imai Y, Iimura T.
    • Journal Title

      Nat Commun

      Volume: 8 Issue: 1 Pages: 2226-2226

    • DOI

      10.1038/s41467-017-02368-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K19546, KAKENHI-PROJECT-17K19728, KAKENHI-PROJECT-16K20412, KAKENHI-PROJECT-26293392, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K18578
  • [Journal Article] Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation2015

    • Author(s)
      Inoue K and Imai Y
    • Journal Title

      BBA-Molecular Basis of Disease.

      Volume: 1852 Issue: 11 Pages: 2432-41

    • DOI

      10.1016/j.bbadis.2015.08.018

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Journal Article] Identification of Novel Transcription Factors in Osteoclast Differentiation using Genome–wide Analysis of Open Chromatin Determined by DNase-seq2014

    • Author(s)
      Inoue K and Imai Y
    • Journal Title

      J Bone Miner Res

      Volume: (Epub ahead of print) Issue: 8 Pages: 1823-1832

    • DOI

      10.1002/jbmr.2229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
  • [Journal Article] Estrogen receptor a in osteocytes regulates trabecular bone fo rmation in female mice.2014

    • Author(s)
      Kondoh S, Inoue K, Igaras hi K, Sugizaki H, Shirode-Fukuda Y, Inoue E, Yu T, Takeuchi JK, Kanno J, Bonewald LF, Imai Y.
    • Journal Title

      Bone

      Volume: 60 Pages: 68-77

    • DOI

      10.1016/j.bone.2013.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02106, KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
  • [Journal Article] Vitamin D receptor in osteoblasts is a negative regulator of bone mass control2013

    • Author(s)
      Yamamoto Y, Yoshizawa T, Fukuda T, Shirode-Fukuda Y, Yu T, Sekine K, Sato T, Kawano H, Aihara K, Naka michi Y, Watanabe T, Shindo M, Inoue K, Inoue E, Tsuji N, Hoshino M, Karsenty G, Metzger D, Chambon P, Kato S, Imai Y.
    • Journal Title

      Endocrinology.

      Volume: 154 Issue: 3 Pages: 1008-20

    • DOI

      10.1210/en.2012-1542

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02106, KAKENHI-PROJECT-23591347, KAKENHI-PROJECT-23659712, KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24614004, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24780094, KAKENHI-PROJECT-25462905, KAKENHI-PUBLICLY-23132502
  • [Journal Article] Novel insights into histone modifiers in Adipogenesis2013

    • Author(s)
      Okuno Y, Inoue K, Imai Y
    • Journal Title

      Adipocyte

      Volume: 2(4) Issue: 4 Pages: 285-8

    • DOI

      10.4161/adip.25731

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
  • [Journal Article] Nuclear Receptors in Bone Physiology and Diseases2013

    • Author(s)
      Imai Y, Youn MY, Inoue K, Takada I, Kouzmenko A, Kato S
    • Journal Title

      Physiol Rev

      Volume: 93(2) Issue: 2 Pages: 481-523

    • DOI

      10.1152/physrev.00008.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-24780094, KAKENHI-PROJECT-25462382
  • [Journal Article] Autoimmune regulator, Aire, is a novel regulator of chondrocyte differentiation2013

    • Author(s)
      Si Y, Inoue K, Igarashi K, Kanno J, Imai Y
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 437(4) Issue: 4 Pages: 579-84

    • DOI

      10.1016/j.bbrc.2013.07.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
  • [Journal Article] Female sex hormones ameliorate arthritis in SKG mice2013

    • Author(s)
      Inoue K, Inoue E, Imai Y
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 434(4) Issue: 4 Pages: 740-5

    • DOI

      10.1016/j.bbrc.2013.03.111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
  • [Journal Article] Nuclear Receptors in Bone Physiology and Diseases2012

    • Author(s)
      Imai Y, Youn MY, Inoue K, Takada I, Kouzmenko A, Kato S
    • Journal Title

      Physiol Rev

      Volume: 93(2) Pages: 481-523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24780094
  • [Presentation] エピゲノム制御因子Uhrf1によるDNAメチル化制御を介した軟骨分化・骨格形成2017

    • Author(s)
      山下美智子,井上和樹,佐伯法学,榊原伊織,李智媛,大塚まき,亀井義明,五十嵐勝秀,高田泰次,飯村忠浩,今井祐記
    • Organizer
      第35回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Presentation] Epigenetic regulator, Uhrf1, is a positive regulator in chondrocyte differentiation2016

    • Author(s)
      Michiko Yamashita,Kazuki Inoue,Iori Sakakibara,Akari Murakami,Yoshiaki Kamei,Yuuki Imai
    • Organizer
      第13回国際人類遺伝学会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Presentation] Epigenetic regulator, Uhrf1, is a positive regulator in chondrocyte differentiation.2016

    • Author(s)
      Michiko Yamashita, Kazuki Inoue, Iori Sakakibara, Akari Murakami, Yoshiaki Kamei, Yuuki Imai
    • Organizer
      第13回国際人類遺伝学会
    • Place of Presentation
      京都
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Presentation] Epigenetic Regulator, Uhrf1, Controls not Only Cell Proliferation but Also Chondrocyte Differentiation During Limb Development.2016

    • Author(s)
      Michiko Yamashita, Kazuki Inoue, Iori Sakakibara, Yuuki Imai
    • Organizer
      The American Society for Bone and Mineral Research 2016 Annual Meeting
    • Place of Presentation
      Atlanta, Georgia, USA
    • Year and Date
      2016-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Presentation] Chromatin remodeling during osteoclast differentiation determined by DNase-seq.2015

    • Author(s)
      Yuuki Imai,Kazuki Inoue
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Presentation] Inhibition of a cholesterol regulator, Srebp2, prevents RANKL-induced bone loss2015

    • Author(s)
      Kazuki Inoue, Yuuki Imai
    • Organizer
      4th Joint Meeting ECTS and IBMS
    • Place of Presentation
      Rotterdam, Netherlands
    • Year and Date
      2015-04-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Presentation] DNase-seqによる破骨細胞分化を制御する新規転写因子の同定2015

    • Author(s)
      井上和樹、今井祐記
    • Organizer
      第1回日本骨免疫学会
    • Place of Presentation
      ホテルブリーズベイマリーナ(沖縄県宮古島市)
    • Year and Date
      2015-06-30
    • Data Source
      KAKENHI-PROJECT-15H04961
  • [Presentation] Identification of Novel Transcription Factors in Osteoclast differentiation using DNase-seq2014

    • Author(s)
      Kazuki Inoue and Yuuki Imai
    • Organizer
      Herbert Fleisch Workshop
    • Place of Presentation
      Brugge, Belgium
    • Data Source
      KAKENHI-PROJECT-24780094
  • [Presentation] Identification of Novel Transcription Factors in Osteoclast differentiation using DNase-seq2014

    • Author(s)
      Kazuki Inoue and Yuuki Imai
    • Organizer
      Herbert Fleisch Workshop
    • Place of Presentation
      Brugge (Belgium)
    • Data Source
      KAKENHI-PROJECT-24780094
  • [Presentation] Dynamic changes in chromatin accessibility during early osteoclastogenesin2013

    • Author(s)
      Kazuki Inoue and Yuuki Imai
    • Organizer
      2^<nd> Joint Meeting of the International Bone and Mineral Society and the Japan Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-24780094
  • [Presentation] Dynamic changes in chromatin accessibility during early osteoclastogenesis2013

    • Author(s)
      Kazuki Inoue and Yuuki Imai
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research.
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24780094
  • [Presentation] Dynamic Changes of Chromatin Accessibility During Early Osteoclastogenesis2012

    • Author(s)
      KAZUKI INOUE, YUUKI IMAI
    • Organizer
      ASBMR 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, USA
    • Data Source
      KAKENHI-PROJECT-24780094
  • [Presentation] Dynamic changes in chromatin accessibility during early osteoclastogenesin2012

    • Author(s)
      Kazuki Inoue and Yuuki Imai
    • Organizer
      ASBMR 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, USA
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-24780094
  • 1.  Yuuki Imai (10423873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 14 results
  • 2.  Sakakibara Iori (50734662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  Yanagihara Yuta
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  Iimura Tadahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  Saeki Noritaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  Lee Jiwon
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  UEHA Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  Matsushima Kouji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  YU T.-y
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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