Inoue Kazuki 井上和樹

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KAZUKI INOUE 井上和樹

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Researcher Number	60623725
Other IDs
Affiliation (based on the past Project Information) *help	2017: 愛媛大学, 学術支援センター, 助教 2012 – 2013: 愛媛大学, 総合科学研究支援センター, 助教
Review Section/Research Field	Principal Investigator Applied biochemistry Except Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 性差 / Y染色体 Except Principal Investigator 遺伝子改変マウス / 分化 / 運動器 / 軟骨細胞 / DNAメチル化 / Uhrf1 / エピジェネティック制御因子 / ゲノムワイド解析 / 軟骨 / エピジェネティクス

Investigation of epigenetic therapeutic targets for musculoskeletal diseases
- Principal Investigator
  
  Yuuki Imai
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Ehime University
Study of Y chromosome gene in sex differences of skeletal growthPrincipal Investigator
- Principal Investigator
  
  KAZUKI INOUE
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Ehime University

All 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression2017
- Author(s)
  Yamashita Michiko、Inoue Kazuki、Saeki Noritaka、Ideta-Otsuka Maky、Yanagihara Yuta、Sawada Yuichiro、Sakakibara Iori、Lee Jiwon、Ichikawa Koichi、Kamei Yoshiaki、Iimura Tadahiro、Igarashi Katsuhide、Takada Yasutsugu、Imai Yuuki
- Journal Title
  
  Development
  
  Volume: 145 Issue: 1 Pages: 157412-157412
- DOI
  10.1242/dev.157412
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19728, KAKENHI-PROJECT-26293392, KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-17H01882, KAKENHI-PROJECT-16K20412
[Journal Article] The HIV co-receptor CCR5 regulates osteoclast function.2017
- Author(s)
  Lee JW, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, Ueha S, Matsushima K, Yamaguchi A, Imai Y, Iimura T.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 2226-2226
- DOI
  10.1038/s41467-017-02368-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-16K11494, KAKENHI-PROJECT-17K19546, KAKENHI-PROJECT-17K19728, KAKENHI-PROJECT-16K20412, KAKENHI-PROJECT-26293392, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-16K15791, KAKENHI-PROJECT-16K18578
[Journal Article] Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation2015
- Author(s)
  Inoue K and Imai Y
- Journal Title
  
  BBA-Molecular Basis of Disease.
  
  Volume: 1852 Issue: 11 Pages: 2432-41
- DOI
  10.1016/j.bbadis.2015.08.018
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04961
[Journal Article] Identification of Novel Transcription Factors in Osteoclast Differentiation using Genome–wide Analysis of Open Chromatin Determined by DNase-seq2014
- Author(s)
  Inoue K and Imai Y
- Journal Title
  
  J Bone Miner Res
  
  Volume: (Epub ahead of print) Issue: 8 Pages: 1823-1832
- DOI
  10.1002/jbmr.2229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
[Journal Article] Estrogen receptor a in osteocytes regulates trabecular bone fo rmation in female mice.2014
- Author(s)
  Kondoh S, Inoue K, Igaras hi K, Sugizaki H, Shirode-Fukuda Y, Inoue E, Yu T, Takeuchi JK, Kanno J, Bonewald LF, Imai Y.
- Journal Title
  
  Bone
  
  Volume: 60 Pages: 68-77
- DOI
  10.1016/j.bone.2013.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02106, KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
[Journal Article] Vitamin D receptor in osteoblasts is a negative regulator of bone mass control2013
- Author(s)
  Yamamoto Y, Yoshizawa T, Fukuda T, Shirode-Fukuda Y, Yu T, Sekine K, Sato T, Kawano H, Aihara K, Naka michi Y, Watanabe T, Shindo M, Inoue K, Inoue E, Tsuji N, Hoshino M, Karsenty G, Metzger D, Chambon P, Kato S, Imai Y.
- Journal Title
  
  Endocrinology.
  
  Volume: 154 Issue: 3 Pages: 1008-20
- DOI
  10.1210/en.2012-1542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02106, KAKENHI-PROJECT-23591347, KAKENHI-PROJECT-23659712, KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24614004, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24780094, KAKENHI-PROJECT-25462905, KAKENHI-PUBLICLY-23132502
[Journal Article] Novel insights into histone modifiers in Adipogenesis2013
- Author(s)
  Okuno Y, Inoue K, Imai Y
- Journal Title
  
  Adipocyte
  
  Volume: 2(4) Issue: 4 Pages: 285-8
- DOI
  10.4161/adip.25731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
[Journal Article] Nuclear Receptors in Bone Physiology and Diseases2013
- Author(s)
  Imai Y, Youn MY, Inoue K, Takada I, Kouzmenko A, Kato S
- Journal Title
  
  Physiol Rev
  
  Volume: 93(2) Issue: 2 Pages: 481-523
- DOI
  10.1152/physrev.00008.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-23791662, KAKENHI-PROJECT-24780094, KAKENHI-PROJECT-25462382
[Journal Article] Autoimmune regulator, Aire, is a novel regulator of chondrocyte differentiation2013
- Author(s)
  Si Y, Inoue K, Igarashi K, Kanno J, Imai Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 437(4) Issue: 4 Pages: 579-84
- DOI
  10.1016/j.bbrc.2013.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
[Journal Article] Female sex hormones ameliorate arthritis in SKG mice2013
- Author(s)
  Inoue K, Inoue E, Imai Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 434(4) Issue: 4 Pages: 740-5
- DOI
  10.1016/j.bbrc.2013.03.111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24780094
[Journal Article] Nuclear Receptors in Bone Physiology and Diseases2012
- Author(s)
  Imai Y, Youn MY, Inoue K, Takada I, Kouzmenko A, Kato S
- Journal Title
  
  Physiol Rev
  
  Volume: 93(2) Pages: 481-523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780094
[Presentation] エピゲノム制御因子Uhrf1によるDNAメチル化制御を介した軟骨分化・骨格形成2017
- Author(s)
  山下美智子,井上和樹,佐伯法学,榊原伊織,李智媛,大塚まき,亀井義明,五十嵐勝秀,高田泰次,飯村忠浩,今井祐記
- Organizer
  第35回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04961
[Presentation] Epigenetic regulator, Uhrf1, is a positive regulator in chondrocyte differentiation2016
- Author(s)
  Michiko Yamashita,Kazuki Inoue,Iori Sakakibara,Akari Murakami,Yoshiaki Kamei,Yuuki Imai
- Organizer
  第13回国際人類遺伝学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04961
[Presentation] Epigenetic regulator, Uhrf1, is a positive regulator in chondrocyte differentiation.2016
- Author(s)
  Michiko Yamashita, Kazuki Inoue, Iori Sakakibara, Akari Murakami, Yoshiaki Kamei, Yuuki Imai
- Organizer
  第13回国際人類遺伝学会
- Place of Presentation
  京都
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04961
[Presentation] Epigenetic Regulator, Uhrf1, Controls not Only Cell Proliferation but Also Chondrocyte Differentiation During Limb Development.2016
- Author(s)
  Michiko Yamashita, Kazuki Inoue, Iori Sakakibara, Yuuki Imai
- Organizer
  The American Society for Bone and Mineral Research 2016 Annual Meeting
- Place of Presentation
  Atlanta, Georgia, USA
- Year and Date
  2016-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04961
[Presentation] Chromatin remodeling during osteoclast differentiation determined by DNase-seq.2015
- Author(s)
  Yuuki Imai,Kazuki Inoue
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15H04961
[Presentation] Inhibition of a cholesterol regulator, Srebp2, prevents RANKL-induced bone loss2015
- Author(s)
  Kazuki Inoue, Yuuki Imai
- Organizer
  4th Joint Meeting ECTS and IBMS
- Place of Presentation
  Rotterdam, Netherlands
- Year and Date
  2015-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04961
[Presentation] DNase-seqによる破骨細胞分化を制御する新規転写因子の同定2015
- Author(s)
  井上和樹、今井祐記
- Organizer
  第1回日本骨免疫学会
- Place of Presentation
  ホテルブリーズベイマリーナ（沖縄県宮古島市）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15H04961
[Presentation] Identification of Novel Transcription Factors in Osteoclast differentiation using DNase-seq2014
- Author(s)
  Kazuki Inoue and Yuuki Imai
- Organizer
  Herbert Fleisch Workshop
- Place of Presentation
  Brugge, Belgium
- Data Source
  KAKENHI-PROJECT-24780094
[Presentation] Identification of Novel Transcription Factors in Osteoclast differentiation using DNase-seq2014
- Author(s)
  Kazuki Inoue and Yuuki Imai
- Organizer
  Herbert Fleisch Workshop
- Place of Presentation
  Brugge (Belgium)
- Data Source
  KAKENHI-PROJECT-24780094
[Presentation] Dynamic changes in chromatin accessibility during early osteoclastogenesin2013
- Author(s)
  Kazuki Inoue and Yuuki Imai
- Organizer
  2^<nd> Joint Meeting of the International Bone and Mineral Society and the Japan Society for Bone and Mineral Research
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-24780094
[Presentation] Dynamic changes in chromatin accessibility during early osteoclastogenesis2013
- Author(s)
  Kazuki Inoue and Yuuki Imai
- Organizer
  2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research.
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24780094
[Presentation] Dynamic Changes of Chromatin Accessibility During Early Osteoclastogenesis2012
- Author(s)
  KAZUKI INOUE, YUUKI IMAI
- Organizer
  ASBMR 2012 Annual Meeting
- Place of Presentation
  Minneapolis, USA
- Data Source
  KAKENHI-PROJECT-24780094
[Presentation] Dynamic changes in chromatin accessibility during early osteoclastogenesin2012
- Author(s)
  Kazuki Inoue and Yuuki Imai
- Organizer
  ASBMR 2012 Annual Meeting
- Place of Presentation
  Minneapolis, USA
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-24780094

1. Yuuki Imai (10423873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. Sakakibara Iori (50734662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. Yanagihara Yuta

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. Iimura Tadahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. Saeki Noritaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. Lee Jiwon

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. UEHA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. Matsushima Kouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. YU T.-y

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Inoue Kazuki 井上 和樹

KAZUKI INOUE 井上 和樹

Research Projects

Research Products

Co-Researchers

Investigation of epigenetic therapeutic targets for musculoskeletal diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of Y chromosome gene in sex differences of skeletal growthPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The HIV co-receptor CCR5 regulates osteoclast function.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fatostatin, an SREBP inhibitor, prevented RANKL-induced bone loss by suppression of osteoclast differentiation2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Novel Transcription Factors in Osteoclast Differentiation using Genome–wide Analysis of Open Chromatin Determined by DNase-seq2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Estrogen receptor a in osteocytes regulates trabecular bone fo rmation in female mice.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vitamin D receptor in osteoblasts is a negative regulator of bone mass control2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel insights into histone modifiers in Adipogenesis2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear Receptors in Bone Physiology and Diseases2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autoimmune regulator, Aire, is a novel regulator of chondrocyte differentiation2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Female sex hormones ameliorate arthritis in SKG mice2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear Receptors in Bone Physiology and Diseases2012

Author(s)

Journal Title

Data Source

[Presentation] エピゲノム制御因子Uhrf1によるDNAメチル化制御を介した軟骨分化・骨格形成2017

Author(s)

Organizer

Data Source

[Presentation] Epigenetic regulator, Uhrf1, is a positive regulator in chondrocyte differentiation2016

Author(s)

Organizer

Place of Presentation

Year and Date

Inoue Kazuki 井上和樹

KAZUKI INOUE 井上和樹