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IZUMIKAWA KEIICHI  泉川 桂一

… Alternative Names

泉川 桂一  イズミカワ ケイイチ

IZUMIKAWA Keiichi  泉川 桂一

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Researcher Number 60625713
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7262-5403
Affiliation (Current) 2025: 明治薬科大学, 薬学部, 准教授
2025: 東京農工大学, (連合)農学研究科(研究院), 特任助教
Affiliation (based on the past Project Information) *help 2018: 東京農工大学, (連合)農学研究科(研究院), 特任助教
2015: 東京農工大学, (連合)農学研究科(研究院), 助教
2015: 東京農工大学, 大学院農学府, 特任助教
2014: 首都大学東京, 理工学研究科, 助教
2014: 東京農工大学, 大学院農学研究院, 助教
2012 – 2013: 東京農工大学, (連合)農学研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 37030:Chemical biology-related
Except Principal Investigator
Plant molecular biology/Plant physiology / Chemical biology
Keywords
Principal Investigator
イントロンリテンション / スプライシング阻害剤 / βサラセミア / スクリーニング / γグロビン / サラセミア / CHTOP / スプライシング
Except Principal Investigator
RNA干渉 / 栄養欠乏ストレス … More / DCL4 / DCL3 / 基質特異性 / 小分子RNA / 2本鎖RNA / DCL4 / DCL3 / シロイヌナズナ / ダイサー / エピジェネティクス / リボソームRNAのプロセシング / エピジェンティック / リボソームRNAプロセシング / エピジェンティクス / 抗がん薬 / タンパク質相互作用 / 転写抑制 / ガン治療 / 機能プロテオミクス / がん / 医薬品探査 / プロテオミクス / ケミカルバイオロジー Less
  • Research Projects

    (3 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (13 People)
  •  βサラセミア治療薬を目指すCHTOPを標的としたスプライシング阻害剤の探索Principal Investigator

    • Principal Investigator
      泉川 桂一
    • Project Period (FY)
      2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Search for drugs targeted against the LYAR cell growth factor

    • Principal Investigator
      Takahashi Nobuhiro
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemical biology
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Enzymatic properties and functional divergence of plant Dicers

    • Principal Investigator
      FUKUHARA Toshiyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plant molecular biology/Plant physiology
    • Research Institution
      Tokyo University of Agriculture and Technology

All 2019 2018 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Patent

  • [Journal Article] TDP-43 regulates site-specific 2'-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs.2019

    • Author(s)
      Izumikawa Keiichi, Nobe Yuko, Ishikawa Hideaki, Yamauchi Yoshio, Taoka Masato, Sato Ko, Nakayama Hiroshi, Simpson RJ, Isobe Toshiaki, Takahashi Nobuhiro.
    • Journal Title

      Nucleic Acids Research

      Volume: 47 Issue: 5 Pages: 2487-2505

    • DOI

      10.1093/nar/gkz086

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05350
  • [Journal Article] Modulating the expression of Chtop, a versatile regulator of gene-specific transcription and mRNA export.2018

    • Author(s)
      Izumikawa Keiichi、Ishikawa Hideaki、Simpson Richard J、Takahashi Nobuhiro
    • Journal Title

      RNA Biology

      Volume: 15 Issue: 7 Pages: 849-855

    • DOI

      10.1080/15476286.2018.1465795

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05350
  • [Journal Article] Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.2015

    • Author(s)
      Yoshikawa H., Ishikawa H., Izumikawa K., Miura Y., Hayano T., Isobe T., Simpson R.J. and Takahashi N.
    • Journal Title

      Nucleic Acids Research

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Journal Article] Comprehensive Analysis of RNA–Protein Complex Using Mass Spectrometry-Based Technology2015

    • Author(s)
      泉川桂一、石川英明、吉川治孝、礒辺俊明、高橋信弘
    • Journal Title

      KAGAKU TO SEIBUTSU

      Volume: 53 Issue: 12 Pages: 850-859

    • DOI

      10.1271/kagakutoseibutsu.53.850

    • NAID

      130005284426

    • ISSN
      0453-073X, 1883-6852
    • Language
      Japanese
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Journal Article] Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.2015

    • Author(s)
      Yoshikawa H, Ishikawa H, Izumikawa K, Miura Y, Hayano T, Isobe T, Simpson RJ, Takahashi N.
    • Journal Title

      Nucleic Acids Res.

      Volume: 43 Issue: 11 Pages: 5524-5536

    • DOI

      10.1093/nar/gkv470

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26500003, KAKENHI-PROJECT-24241075
  • [Journal Article] Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5’-3’ exoribonuclease) in the nucleoplasm.2015

    • Author(s)
      Sato+, S., Ishikawa+, H., Yoshikawa, H., Izumikawa, K., Simpson, R.J. and Takahashi, N.
    • Journal Title

      Nucleic Acids Res.

      Volume: 43 Pages: 10397-10397

    • DOI

      10.1093/nar/gkv1069

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Journal Article] Human cell growth regulator Ly-1 antibody reactive homolog accelerates processing of pre-ribosomal RNA2014

    • Author(s)
      Miyazawa N., Yoshikawa, H., Magae S., Ishikawa H., Izumikawa K., Terukina G., Suzuki A, Nakamura-Fujiyama S., Miura Y., Hayano T, Komatsu K., Isobe T, and Takahashi N.
    • Journal Title

      Genes to Cells

      Volume: 19 Issue: 4 Pages: 273-286

    • DOI

      10.1111/gtc.12129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Patent] 細胞増殖促進剤及び癌細胞増殖抑制剤の単離方法2016

    • Inventor(s)
      宮澤直樹、高橋信弘、泉川桂一、石川英明、吉川治孝
    • Industrial Property Rights Holder
      宮澤直樹、高橋信弘、泉川桂一、石川英明、吉川治孝
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-057432
    • Filing Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Patent] TDP-43細胞内存在量関連疾患の認定方法2013

    • Inventor(s)
      泉川桂一、高橋信弘、他
    • Industrial Property Rights Holder
      東京農工大学・首都大学東京
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-02-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] The Role of Nucleolar Protein Nop52 in the pre-rRNA Processing During Human Ribosome Biogenesis by Proteomic Approach2013

    • Author(s)
      Yoshikawa, H., Ishikawa, H., Izumikawa, K., Hayano, T., Miura, Y., Yamauchi, Y., Isobe, T., Takahashi, N.
    • Organizer
      HUPO 12th Annual Wold Congress-JHUPO 2013 Anual Joint Congress
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] Human cell growth regulator LYAR is highly expressed in many tumors and accelerates ribosome biogenesis.2013

    • Author(s)
      Izumikawa, K., Miyazawa, N., Yoshikawa, H., Ishikawa, H., Terukina, G., Miura, Y., Hayano, T., Isobe, T., Watanabe, A., Aburatani, H., Takahashi, N.
    • Organizer
      HUPO 12th Annual Wold Congress-JHUPO 2013 Anual Joint Congress
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] ヒトリボソーム40Sサブユニット生合成におけるPARNタンパク質の役割2013

    • Author(s)
      石川英明、泉川桂一、吉川治孝、礒辺俊明、高橋信弘(高橋信弘)
    • Organizer
      第2回RIBOSOME MEETING
    • Place of Presentation
      東京、東京農工大学農学部
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] プロテオミクスの手法を用いた核小体タンパク質Nop52のヒトリボソーム生合成における役割の解明2012

    • Author(s)
      吉川治孝、川崎実由希、早野俊哉、泉川桂一、石川英明、山内芳雄、礒辺俊明、高橋信弘(高橋信弘)
    • Organizer
      日本プロテオーム学会2012大会(10th JHUPO conference)
    • Place of Presentation
      東京、日本科学未来館
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] 多種類の腫瘍細胞で高発現しているヒト細胞増殖因子LYARはリボソーム生合成を昂進している2012

    • Author(s)
      宮澤直樹、吉川治孝、馬替恵美、石川英明、泉川桂一、照喜名悟朗、鈴木愛、藤山-中村沙理1、三浦豊、早野俊哉、礒辺俊明、渡辺亮、油谷裕幸、高橋信弘(高橋信弘)
    • Organizer
      日本プロテオーム学会2012大会(10th JHUPO conference)
    • Place of Presentation
      東京、日本科学未来館
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] 癌抑制因子Arfの相互作用タンパク質CARFの細胞増殖における新規機能2012

    • Author(s)
      佐藤慈子、石川英明、泉川桂一、高橋信弘(高橋信弘)
    • Organizer
      日本プロテオーム学会2012大会(10th JHUPO conference)
    • Place of Presentation
      東京、日本科学未来館
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] ヒト細胞増殖因子LYARは多種類の腫瘍細胞で高発現しておりリボソーム合成を昂進している

    • Author(s)
      吉川治孝、宮澤直樹、馬替恵美、石川英明、泉川桂一、照喜名悟朗、三浦豊、早野俊哉、礒辺俊明、渡辺亮、油谷裕幸、高橋信弘
    • Organizer
      日本プロテオーム学会2014(JHUPO2014)
    • Place of Presentation
      つくば国際会議場、筑波
    • Year and Date
      2014-07-14 – 2014-07-15
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] リボヌクレアーゼを介したヒトリボソーム生合成調節機構

    • Author(s)
      石川英明、佐藤慈子、泉川桂一、吉川治孝3、礒辺俊明、高橋信弘
    • Organizer
      第三回リボソームミーティング
    • Place of Presentation
      ANAホリデイ・イン リゾート 宮崎
    • Year and Date
      2015-03-17 – 2015-03-18
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] プロテオミクスによるヒトのリボソーム合成過程の解析

    • Author(s)
      吉川治孝、石川英明、泉川桂一、高橋信弘
    • Organizer
      第三回リボソームミーティング
    • Place of Presentation
      ANAホリデイ・イン リゾート 宮崎
    • Year and Date
      2015-03-17 – 2015-03-18
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] 細胞増殖制御因子hLARのリボソーム生合成経路における機能解析

    • Author(s)
      泉川桂一、宮澤直樹、石川英明、吉川治孝、長橋花織、高橋信弘
    • Organizer
      第三回リボソームミーティング
    • Place of Presentation
      ANAホリデイ・イン リゾート 宮崎
    • Year and Date
      2015-03-17 – 2015-03-18
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] リボヌクレオプロテオミクスによる疾患解析

    • Author(s)
      高橋信弘、石川英明、泉川桂一、中山洋、田岡万悟、礒辺俊明(高橋信弘)
    • Organizer
      第8回臨床プロテオーム研究会
    • Place of Presentation
      東京、都市センターホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-24241075
  • [Presentation] ガン細胞に特異的なリボソーム合成促進因子をターゲットとした細胞増殖阻害物質探索法の開発

    • Author(s)
      泉川桂一、吉川治孝、石川英明、高橋信弘
    • Organizer
      東京バイオマーカー・イノベーション技術組合 TOBIRA研究交流フォーラム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24241075
  • 1.  ISHIKAWA Hideaki (80625715)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 2.  Takahashi Nobuhiro (80293017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 3.  MIURA Yutaka (10219595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 4.  YOSHIKAWA Harunori (60709567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 5.  ISOBE Toshiaki (70106607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  FUKUHARA Toshiyuki (90228924)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  HABU Yoshiki (80266915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YOSHIKAWA Manabu (80391564)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ISHII Kazuo (60449238)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KOZAKI Toshinori (60442828)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NAGANO Hideaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SETA Atsushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  磯部 俊明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 10 results

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