IZUMIKAWA KEIICHI 泉川桂一

… Alternative Names

泉川桂一イズミカワケイイチ

IZUMIKAWA Keiichi 泉川桂一

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Researcher Number	60625713
Other IDs	https://orcid.org/0000-0001-7262-5403
Affiliation (Current)	2024: 明治薬科大学, 薬学部, 准教授 2024: 東京農工大学, (連合)農学研究科(研究院), 特任助教
Affiliation (based on the past Project Information) *help	2018: 東京農工大学, (連合)農学研究科(研究院), 特任助教 2015: 東京農工大学, (連合)農学研究科(研究院), 助教 2015: 東京農工大学, 大学院農学府, 特任助教 2014: 首都大学東京, 理工学研究科, 助教 2014: 東京農工大学, 大学院農学研究院, 助教 2012 – 2013: 東京農工大学, (連合)農学研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related Except Principal Investigator Plant molecular biology/Plant physiology / Chemical biology
Keywords	Principal Investigator イントロンリテンション / スプライシング阻害剤 / βサラセミア / スクリーニング / γグロビン / サラセミア / CHTOP / スプライシング Except Principal Investigator RNA干渉 / 栄養欠乏ストレス … More / DCL4 / DCL3 / 基質特異性 / 小分子ＲＮＡ / ２本鎖ＲＮＡ / ＤＣＬ４ / ＤＣＬ３ / シロイヌナズナ / ダイサー / エピジェネティクス / リボソームRNAのプロセシング / エピジェンティック / リボソームRNAプロセシング / エピジェンティクス / 抗がん薬 / タンパク質相互作用 / 転写抑制 / ガン治療 / 機能プロテオミクス / がん / 医薬品探査 / プロテオミクス / ケミカルバイオロジー Less

βサラセミア治療薬を目指すCHTOPを標的としたスプライシング阻害剤の探索Principal Investigator
- Principal Investigator
  
  泉川桂一
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Tokyo University of Agriculture and Technology
Search for drugs targeted against the LYAR cell growth factor
- Principal Investigator
  
  Takahashi Nobuhiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Chemical biology
- Research Institution
  Tokyo University of Agriculture and Technology
Enzymatic properties and functional divergence of plant Dicers
- Principal Investigator
  
  FUKUHARA Toshiyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plant molecular biology/Plant physiology
- Research Institution
  Tokyo University of Agriculture and Technology

All 2019 2018 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Patent

[Journal Article] TDP-43 regulates site-specific 2'-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs.2019
- Author(s)
  Izumikawa Keiichi, Nobe Yuko, Ishikawa Hideaki, Yamauchi Yoshio, Taoka Masato, Sato Ko, Nakayama Hiroshi, Simpson RJ, Isobe Toshiaki, Takahashi Nobuhiro.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Issue: 5 Pages: 2487-2505
- DOI
  10.1093/nar/gkz086
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05350
[Journal Article] Modulating the expression of Chtop, a versatile regulator of gene-specific transcription and mRNA export.2018
- Author(s)
  Izumikawa Keiichi、Ishikawa Hideaki、Simpson Richard J、Takahashi Nobuhiro
- Journal Title
  
  RNA Biology
  
  Volume: 15 Issue: 7 Pages: 849-855
- DOI
  10.1080/15476286.2018.1465795
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05350
[Journal Article] Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.2015
- Author(s)
  Yoshikawa H., Ishikawa H., Izumikawa K., Miura Y., Hayano T., Isobe T., Simpson R.J. and Takahashi N.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24241075
[Journal Article] Comprehensive Analysis of RNA–Protein Complex Using Mass Spectrometry-Based Technology2015
- Author(s)
  泉川桂一、石川英明、吉川治孝、礒辺俊明、高橋信弘
- Journal Title
  
  KAGAKU TO SEIBUTSU
  
  Volume: 53 Issue: 12 Pages: 850-859
- DOI
  10.1271/kagakutoseibutsu.53.850
- NAID
  130005284426
- ISSN
  0453-073X, 1883-6852
- Language
  Japanese
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24241075
[Journal Article] Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.2015
- Author(s)
  Yoshikawa H, Ishikawa H, Izumikawa K, Miura Y, Hayano T, Isobe T, Simpson RJ, Takahashi N.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 43 Issue: 11 Pages: 5524-5536
- DOI
  10.1093/nar/gkv470
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26500003, KAKENHI-PROJECT-24241075
[Journal Article] Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5’-3’ exoribonuclease) in the nucleoplasm.2015
- Author(s)
  Sato+, S., Ishikawa+, H., Yoshikawa, H., Izumikawa, K., Simpson, R.J. and Takahashi, N.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 43 Pages: 10397-10397
- DOI
  10.1093/nar/gkv1069
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24241075
[Journal Article] Human cell growth regulator Ly-1 antibody reactive homolog accelerates processing of pre-ribosomal RNA2014
- Author(s)
  Miyazawa N., Yoshikawa, H., Magae S., Ishikawa H., Izumikawa K., Terukina G., Suzuki A, Nakamura-Fujiyama S., Miura Y., Hayano T, Komatsu K., Isobe T, and Takahashi N.
- Journal Title
  
  Genes to Cells
  
  Volume: 19 Issue: 4 Pages: 273-286
- DOI
  10.1111/gtc.12129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24241075
[Patent] 細胞増殖促進剤及び癌細胞増殖抑制剤の単離方法2016
- Inventor(s)
  宮澤直樹、高橋信弘、泉川桂一、石川英明、吉川治孝
- Industrial Property Rights Holder
  宮澤直樹、高橋信弘、泉川桂一、石川英明、吉川治孝
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-057432
- Filing Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-24241075
[Patent] TDP-43細胞内存在量関連疾患の認定方法2013
- Inventor(s)
  泉川桂一、高橋信弘、他
- Industrial Property Rights Holder
  東京農工大学・首都大学東京
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-28
- Overseas
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] The Role of Nucleolar Protein Nop52 in the pre-rRNA Processing During Human Ribosome Biogenesis by Proteomic Approach2013
- Author(s)
  Yoshikawa, H., Ishikawa, H., Izumikawa, K., Hayano, T., Miura, Y., Yamauchi, Y., Isobe, T., Takahashi, N.
- Organizer
  HUPO 12th Annual Wold Congress-JHUPO 2013 Anual Joint Congress
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] Human cell growth regulator LYAR is highly expressed in many tumors and accelerates ribosome biogenesis.2013
- Author(s)
  Izumikawa, K., Miyazawa, N., Yoshikawa, H., Ishikawa, H., Terukina, G., Miura, Y., Hayano, T., Isobe, T., Watanabe, A., Aburatani, H., Takahashi, N.
- Organizer
  HUPO 12th Annual Wold Congress-JHUPO 2013 Anual Joint Congress
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] ヒトリボソーム40Sサブユニット生合成におけるPARNタンパク質の役割2013
- Author(s)
  石川英明、泉川桂一、吉川治孝、礒辺俊明、高橋信弘（高橋信弘）
- Organizer
  第2回RIBOSOME MEETING
- Place of Presentation
  東京、東京農工大学農学部
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] プロテオミクスの手法を用いた核小体タンパク質Nop52のヒトリボソーム生合成における役割の解明2012
- Author(s)
  吉川治孝、川崎実由希、早野俊哉、泉川桂一、石川英明、山内芳雄、礒辺俊明、高橋信弘（高橋信弘）
- Organizer
  日本プロテオーム学会2012大会（10th JHUPO conference）
- Place of Presentation
  東京、日本科学未来館
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] 多種類の腫瘍細胞で高発現しているヒト細胞増殖因子LYARはリボソーム生合成を昂進している2012
- Author(s)
  宮澤直樹、吉川治孝、馬替恵美、石川英明、泉川桂一、照喜名悟朗、鈴木愛、藤山-中村沙理1、三浦豊、早野俊哉、礒辺俊明、渡辺亮、油谷裕幸、高橋信弘（高橋信弘）
- Organizer
  日本プロテオーム学会2012大会（10th JHUPO conference）
- Place of Presentation
  東京、日本科学未来館
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] 癌抑制因子Arfの相互作用タンパク質CARFの細胞増殖における新規機能2012
- Author(s)
  佐藤慈子、石川英明、泉川桂一、高橋信弘（高橋信弘）
- Organizer
  日本プロテオーム学会2012大会（10th JHUPO conference）
- Place of Presentation
  東京、日本科学未来館
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] ヒト細胞増殖因子LYARは多種類の腫瘍細胞で高発現しておりリボソーム合成を昂進している
- Author(s)
  吉川治孝、宮澤直樹、馬替恵美、石川英明、泉川桂一、照喜名悟朗、三浦豊、早野俊哉、礒辺俊明、渡辺亮、油谷裕幸、高橋信弘
- Organizer
  日本プロテオーム学会2014（JHUPO2014）
- Place of Presentation
  つくば国際会議場、筑波
- Year and Date
  2014-07-14 – 2014-07-15
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] リボヌクレアーゼを介したヒトリボソーム生合成調節機構
- Author(s)
  石川英明、佐藤慈子、泉川桂一、吉川治孝3、礒辺俊明、高橋信弘
- Organizer
  第三回リボソームミーティング
- Place of Presentation
  ANAホリデイ・インリゾート宮崎
- Year and Date
  2015-03-17 – 2015-03-18
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] プロテオミクスによるヒトのリボソーム合成過程の解析
- Author(s)
  吉川治孝、石川英明、泉川桂一、高橋信弘
- Organizer
  第三回リボソームミーティング
- Place of Presentation
  ANAホリデイ・インリゾート宮崎
- Year and Date
  2015-03-17 – 2015-03-18
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] 細胞増殖制御因子hLARのリボソーム生合成経路における機能解析
- Author(s)
  泉川桂一、宮澤直樹、石川英明、吉川治孝、長橋花織、高橋信弘
- Organizer
  第三回リボソームミーティング
- Place of Presentation
  ANAホリデイ・インリゾート宮崎
- Year and Date
  2015-03-17 – 2015-03-18
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] リボヌクレオプロテオミクスによる疾患解析
- Author(s)
  高橋信弘、石川英明、泉川桂一、中山洋、田岡万悟、礒辺俊明（高橋信弘）
- Organizer
  第8回臨床プロテオーム研究会
- Place of Presentation
  東京、都市センターホテル
- Invited
- Data Source
  KAKENHI-PROJECT-24241075
[Presentation] ガン細胞に特異的なリボソーム合成促進因子をターゲットとした細胞増殖阻害物質探索法の開発
- Author(s)
  泉川桂一、吉川治孝、石川英明、高橋信弘
- Organizer
  東京バイオマーカー・イノベーション技術組合　TOBIRA研究交流フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24241075

1. ISHIKAWA Hideaki (80625715)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. Takahashi Nobuhiro (80293017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
3. MIURA Yutaka (10219595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. YOSHIKAWA Harunori (60709567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. ISOBE Toshiaki (70106607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUKUHARA Toshiyuki (90228924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HABU Yoshiki (80266915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YOSHIKAWA Manabu (80391564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHII Kazuo (60449238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KOZAKI Toshinori (60442828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGANO Hideaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SETA Atsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 磯部俊明

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results

IZUMIKAWA KEIICHI 泉川 桂一

泉川 桂一 イズミカワ ケイイチ

IZUMIKAWA Keiichi 泉川 桂一

Research Projects

Research Products

Co-Researchers

βサラセミア治療薬を目指すCHTOPを標的としたスプライシング阻害剤の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for drugs targeted against the LYAR cell growth factor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enzymatic properties and functional divergence of plant Dicers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] TDP-43 regulates site-specific 2'-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulating the expression of Chtop, a versatile regulator of gene-specific transcription and mRNA export.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.2015

Author(s)

Journal Title

Data Source

[Journal Article] Comprehensive Analysis of RNA&#x2013;Protein Complex Using Mass Spectrometry-Based Technology2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Human nucleolar protein Nop52 (RRP1/NNP-1) is involved in site 2 cleavage in internal transcribed spacer 1 of pre-rRNAs at early stages of ribosome biogenesis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5’-3’ exoribonuclease) in the nucleoplasm.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human cell growth regulator Ly-1 antibody reactive homolog accelerates processing of pre-ribosomal RNA2014

Author(s)

Journal Title

DOI

Data Source

[Patent] 細胞増殖促進剤及び癌細胞増殖抑制剤の単離方法2016

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] TDP-43細胞内存在量関連疾患の認定方法2013

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] The Role of Nucleolar Protein Nop52 in the pre-rRNA Processing During Human Ribosome Biogenesis by Proteomic Approach2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Human cell growth regulator LYAR is highly expressed in many tumors and accelerates ribosome biogenesis.2013

IZUMIKAWA KEIICHI 泉川桂一

泉川桂一イズミカワケイイチ

IZUMIKAWA Keiichi 泉川桂一

[Journal Article] Comprehensive Analysis of RNA–Protein Complex Using Mass Spectrometry-Based Technology2015