Karasawa Tadayoshi 唐澤直義

… Alternative Names

KARASAWA Tadayoshi 唐澤直義

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Researcher Number	60631893
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 自治医科大学, 医学部, 講師 2013 – 2019: 自治医科大学, 医学部, 助教 2012: 自治医科大学, 医学部, ポストドクター
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 49010:Pathological biochemistry-related / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Basic Section 53020:Cardiology-related / Basic Section 54020:Connective tissue disease and allergy-related / Cardiovascular medicine / Basic Section 53040:Nephrology-related / Endocrinology
Keywords	Principal Investigator マクロファージ / インフラマソーム / 動脈硬化 / 炎症 / カスパーゼ / コレステロール結晶 / 好中球 / 細胞死 / サイトカイン / 飽和脂肪酸 … More / 慢性炎症 / カスパーゼ1 / インターロイキン / 制御された細胞死 / フェロトーシス / 炎症性カスパーゼ / 炎症性カスパーぜ / パイロトーシス / 脂質結晶 / Interleukin-1 / カスパーゼ-1 / 脂肪酸組成 / インスリン抵抗性 / 自然免疫 / 脂肪酸 … More Except Principal Investigator 炎症 / インフラマソーム / ユビキチン / 心血管病 / 炎症反応 / サイトカイン / 心血管疾患 / 細胞死 / 自然免疫 / 免疫 / タンパク質修飾 / β2ミクログロブリン / IP-10 / I型インターフェロン / 急速進行性間質性肺炎 / 抗MDA-5抗体陽性皮膚筋炎 / 慢性腎臓病 / 急性腎障害 / カリウム / メチロソーム / プロテアソーム / 川崎病 / 血管炎 / CAWS / 骨髄由来樹状細胞 / IL-1β / NLRP3インフラマソーム / CAWS血管炎 / 川崎病様血管炎 / タンパク質分解 / 免疫学 / ユビキチン化 / マクロファージ / ユビキチン修飾 / 血栓症 / 生活習慣病 Less

ステロール合成経路による細胞死の制御機構の解明Principal Investigator
- Principal Investigator
  
  唐澤直義
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Jichi Medical University
Role and mechanism of the inflammasome, a regulator of inflammation and cell death, in cardiovascular disease
- Principal Investigator
  
  高橋将文
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
The mechanism of immune regulation of potassium-dependent kidney response
- Principal Investigator
  
  駒田敬則
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Jichi Medical University
Analysis of the Involvement of the Type I IFN/IP-10 Axis and Pyroptosis Pathway in Anti-MDA-5 Antibody Positive Dermatomyositis
- Principal Investigator
  
  中村潤
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Jichi Medical University
The role of caspase-11-dependent pyroptosis in atherosclerotic lesionPrincipal Investigator
- Principal Investigator
  
  Karasawa Tadayoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Jichi Medical University
Role and Mechanism of a novel E3 ligase ARIH2 in Cardiovascular Disease
- Principal Investigator
  
  Takahashi Masafumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
Mechanism of NLRP3 inflammasome in CAWS-induced vasculitis
- Principal Investigator
  
  Nakamura Jun
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Jichi Medical University
Role of ARIH2 in the inflammasome-related cardiovascular disease
- Principal Investigator
  
  Takahashi Masafumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Jichi Medical University
Neutrophils in inflammatory response induced by lipid crystalsPrincipal Investigator
- Principal Investigator
  
  Karasawa Tadayoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Jichi Medical University
Role of adapter molecule ASC independent of inflammasome
- Principal Investigator
  
  Kawanishi Fumitake
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Toyama Prefectural University
The role of inflammasome in prolonged inflammation of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  Tadayoshi Karasawa
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical University
The study about inflammasome regulation system by protein degradation
- Principal Investigator
  
  Kawashima Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Teikyo University
Molecular mechanisms underlying inflammasome-mediated cardiovascular disease
- Principal Investigator
  
  Takahashi Masafumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Jichi Medical University
Regulation of NLRP3 inflammasome by modulation of lipid metabolismsPrincipal Investigator
- Principal Investigator
  
  Karasawa Tadayoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical University
Elucidation of novel regulatory mechanisms of inflammasome in metabolic diseasePrincipal Investigator
- Principal Investigator
  
  KARASAWA Tadayoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Metabolomics
- Research Institution
  Jichi Medical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2012 Other

All Journal Article Presentation Other

[Journal Article] Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice2023
- Author(s)
  Karasawa Tadayoshi、Komada Takanori、Baatarjav Chintogtokh、Aizawa Emi、Mizushina Yoshiko、Fujimura Kenta、Gunji Yoshitaka、Komori Satoko、Aizawa Hidetoshi、Jing Tao Cantona Billton、Matsumura Takayoshi、Takahashi Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 686 Pages: 149158-149158
- DOI
  10.1016/j.bbrc.2023.149158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15139, KAKENHI-PROJECT-21K06875, KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-22K16225, KAKENHI-PROJECT-22K20864
[Journal Article] NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy2023
- Author(s)
  Fujimura Kenta、Karasawa Tadayoshi、Komada Takanori、Yamada Naoya、Mizushina Yoshiko、Baatarjav Chintogtokh、Matsumura Takayoshi、Otsu Kinya、Takeda Norihiko、Mizukami Hiroaki、Kario Kazuomi、Takahashi Masafumi
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 180 Pages: 58-68
- DOI
  10.1016/j.yjmcc.2023.05.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15139, KAKENHI-PROJECT-21K06875, KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-22K16225, KAKENHI-PROJECT-22K20864
[Journal Article] A Myb enhancer-guided analysis of basophil and mast cell differentiation2022
- Author(s)
  Matsumura Takayoshi、Totani Haruhito、Gunji Yoshitaka、Fukuda Masahiro、Yokomori Rui、Deng Jianwen、Rethnam Malini、Yang Chong、Tan Tze King、Karasawa Tadayoshi、Kario Kazuomi、Takahashi Masafumi、Osato Motomi、Sanda Takaomi、Suda Toshio
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7064-7064
- DOI
  10.1038/s41467-022-34906-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-21K19514, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-19K07668, KAKENHI-PROJECT-23K24165
[Journal Article] Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome2022
- Author(s)
  Karasawa Tadayoshi、Komada Takanori、Yamada Naoya、Aizawa Emi、Mizushina Yoshiko、Watanabe Sachiko、Baatarjav Chintogtokh、Matsumura Takayoshi、Takahashi Masafumi
- Journal Title
  
  eLife
  
  Volume: 11 Pages: 1-26
- DOI
  10.7554/elife.75166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06875, KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-22K20864, KAKENHI-PROJECT-20K17290
[Journal Article] NLRP3 inflammasome is involved in testicular inflammation induced by lipopolysaccharide in mice2022
- Author(s)
  Sano Michiya、Komiyama Hiromu、Shinoda Riina、Ozawa Ren、Watanabe Hiroyuki、Karasawa Tadayoshi、Takahashi Masafumi、Torii Yasushi、Iwata Hisataka、Kuwayama Takehito、Shirasuna Koumei
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 87 Issue: 4
- DOI
  10.1111/aji.13527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21J13082, KAKENHI-PROJECT-21K08114
[Journal Article] dsDNA-induced AIM2 pyroptosis halts aberrant inflammation during rhabdomyolysis-induced acute kidney injury2022
- Author(s)
  Baatarjav Chintogtokh、Komada Takanori、Karasawa Tadayoshi、Yamada Naoya、Sampilvanjil Ariunaa、Matsumura Takayoshi、Takahashi Masafumi
- Journal Title
  
  Cell Death & Differentiation
  
  Volume: 29 Issue: 12 Pages: 2487-2502
- DOI
  10.1038/s41418-022-01033-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06875, KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-22K20864, KAKENHI-PROJECT-20K17290
[Journal Article] Calciprotein Particles Induce IL-1β/α?Mediated Inflammation through NLRP3 Inflammasome-Dependent and -Independent Mechanisms2021
- Author(s)
  Anzai Fumiya、Karasawa Tadayoshi、Komada Takanori、Yamada Naoya、Miura Yutaka、Sampilvanjil Ariunaa、Baatarjav Chintogtokh、Fujimura Kenta、Matsumura Takayoshi、Tago Kenji、Kurosu Hiroshi、Takeishi Yasuchika、Kuro-O Makoto、Takahashi Masafumi
- Journal Title
  
  ImmunoHorizons
  
  Volume: 5 Issue: 7 Pages: 602-614
- DOI
  10.4049/immunohorizons.2100066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-21K06875, KAKENHI-PROJECT-21K08114, KAKENHI-PROJECT-20K17290
[Journal Article] Crucial role of NLRP3 inflammasome in a murine model of Kawasaki disease.2020
- Author(s)
  4)Anzai F, Watanabe S, Kimura H, Kamata R, Karasawa T, Komada T, Nakamura J, Nagi-Miura N, Ohno N, Takeishi Y, Takahashi M
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 138 Pages: 185-196
- DOI
  10.1016/j.yjmcc.2019.11.158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-19K08523, KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-19K08916
[Journal Article] NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury2020
- Author(s)
  Ito Homare、Kimura Hiroaki、Karasawa Tadayoshi、Hisata Shu、Sadatomo Ai、Inoue Yoshiyuki、Yamada Naoya、Aizawa Emi、Hishida Erika、Kamata Ryo、Komada Takanori、Watanabe Sachiko、Kasahara Tadashi、Suzuki Takuji、Horie Hisanaga、Kitayama Joji、Sata Naohiro、Yamaji-Kegan Kazuyo、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 205 Issue: 5 Pages: 1393-1405
- DOI
  10.4049/jimmunol.2000217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K08630, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290, KAKENHI-PROJECT-20K17629, KAKENHI-PROJECT-17K09889
[Journal Article] GSDME-Dependent Incomplete Pyroptosis Permits Selective IL-1α Release under Caspase-1 Inhibition2020
- Author(s)
  Aizawa Emi、Karasawa Tadayoshi、Watanabe Sachiko、Komada Takanori、Kimura Hiroaki、Kamata Ryo、Ito Homare、Hishida Erika、Yamada Naoya、Kasahara Tadashi、Mori Yoshiyuki、Takahashi Masafumi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 5 Pages: 101070-101070
- DOI
  10.1016/j.isci.2020.101070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-20K17290
[Journal Article] GSDME-dependentincomplete pyroptosis permits selective IL-1α release under caspase-1 inhibition2020
- Author(s)
  Aizawa E, Karasawa T, Watanabe S, Komada T, Kimura H, Kamata R, ItoH, Hishida E, Yamada N, Kasahara T, Mori Y, Takahashi M
- Journal Title
  
  iScience
  
  Volume: －
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: potential role of ferroptosis.2020
- Author(s)
  3)Yamada N, Karasawa T, Wakiya T, Sadatomo A, Ito H, Kamata R, Watanabe S, Komada T, Kimura H, Sanada Y, Sakuma Y, Mizuta K, Sata N, Takahashi M
- Journal Title
  
  Am J Transplant
  
  Volume: - Issue: 6 Pages: 1606-1618
- DOI
  10.1111/ajt.15773
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K16329, KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-20K07365
[Journal Article] Role of the NLRP3 Inflammasome in Preeclampsia2020
- Author(s)
  Shirasuna Koumei、Karasawa Tadayoshi、Takahashi Masafumi
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 11 Pages: 80-80
- DOI
  10.3389/fendo.2020.00080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome2020
- Author(s)
  Watanabe Sachiko、Usui-Kawanishi Fumitake、Komada Takanori、Karasawa Tadayoshi、Kamata Ryo、Yamada Naoya、Kimura Hiroaki、Dezaki Katsuya、Ohmori Tsukasa、Takahashi Masafumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 531 Issue: 2 Pages: 125-132
- DOI
  10.1016/j.bbrc.2020.07.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K08524, KAKENHI-PROJECT-19K06358, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290, KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08370
[Journal Article] Glucose regulates hypoxia-induced NLRP3 inflammasome activation in macrophages.2020
- Author(s)
  1)Watanabe S, Usui-Kawanishi F, Karasawa, Kimura H, Kamata R, Inoue, Mise N, Kasahara T, Takahashi M
- Journal Title
  
  J Cell Physiol
  
  Volume: - Issue: 10 Pages: 7554-7566
- DOI
  10.1002/jcp.29659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-19K21319, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K06358, KAKENHI-PROJECT-20K07365, KAKENHI-PROJECT-20K17290
[Journal Article] Ferroptosis driven by radical oxidation of n-6 fatty acids mediates acetaminophen-induced acute liver failure.2020
- Author(s)
  2)Yamada N, Karasawa T, Kimura H, Watanabe S, Komada T, Kamata R, Sampilvanjil A, Ito J, Nakagawa K, Kuwata H, Hara S, Sakuma Y, Sata N, Takahashi M
- Journal Title
  
  Cell Death Dis
  
  Volume: 11 Issue: 2 Pages: 144-144
- DOI
  10.1038/s41419-020-2334-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-19K07087, KAKENHI-PROJECT-19H03375, KAKENHI-PROJECT-19K21319
[Journal Article] Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells2020
- Author(s)
  Sampilvanjil Ariunaa、Karasawa Tadayoshi、Yamada Naoya、Komada Takanori、Higashi Tsunehito、Baatarjav Chintogtokh、Watanabe Sachiko、Kamata Ryo、Ohno Nobuhiko、Takahashi Masafumi
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 318 Issue: 3 Pages: H508-H518
- DOI
  10.1152/ajpheart.00559.2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K11654, KAKENHI-PROJECT-19K21319
[Journal Article] Palmitic acid activates NLRP3 inflammasome and induces placental inflammation during pregnancy in mice2020
- Author(s)
  SANO Michiya、SHIMAZAKI Sayaka、KANEKO Yasuaki、KARASAWA Tadayoshi、TAKAHASHI Masafumi、OHKUCHI Akihide、TAKAHASHI Hironori、KUROSAWA Akira、TORII Yasushi、IWATA Hisataka、KUWAYAMA Takehito、SHIRASUNA Koumei
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 66 Issue: 3 Pages: 241-248
- DOI
  10.1262/jrd.2020-007
- NAID
  130007853972
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] Glucose regulates hypoxia-induced NLRP3inflammasome activation in macrophages2020
- Author(s)
  Watanabe S, Usui-Kawanishi F, Karasawa T, Kimura H, Kamata R, InoueY, Mise N, Kasahara T, Takahashi M
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: －
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] Crucial role of NLRP3 inflammasome in the development of peritoneal dialysis-related peritoneal fibrosis.2019
- Author(s)
  6)Hishida E, Ito H, Komada T, Karasawa T, Kimura H, Watanabe S, Kamata R, Aizawa E, Kasahara T, Morishita Y, AkimotoT, Nagata D, Takahashi M
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 10363-10363
- DOI
  10.1038/s41598-019-46504-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K15900, KAKENHI-PROJECT-18K16329, KAKENHI-PROJECT-19K21319
[Journal Article] Role of TLR5 in inflammation and tissue damage after intestinal ischemia-reperfusion injury.2019
- Author(s)
  7)Ito H, Sadatomo A, Inoue Y, Yamada N, Aizawa E, Hishida E, Kamata R, Karasawa T, Kimura H, Watanabe S, Komada T, Horie H, Kitagawa J, Sata N, Takahashi M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 519 Issue: 1 Pages: 15-22
- DOI
  10.1016/j.bbrc.2019.08.083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K15900, KAKENHI-PROJECT-18K16329, KAKENHI-PROJECT-19K21319
[Journal Article] Inflammasome-independent and atypical processing of IL-1β contributes to acid aspiration-induced acute lung injury.2019
- Author(s)
  5)Mizushina Y, Karasawa T, Aizawa K, Kimura H, Watanabe S, Kamata R, Komada T, Mato N, Kasahara T, Koyama S, Bando M, Hagiwara K, Takahashi M
- Journal Title
  
  J Immunol
  
  Volume: 203 Issue: 1 Pages: 236-246
- DOI
  10.4049/jimmunol.1900168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K15900, KAKENHI-PROJECT-19K21319
[Journal Article] Saturated fatty acid-crystals activate NLRP3 inflammasome2019
- Author(s)
  Karasawa Tadayoshi、Takahashi Masafumi
- Journal Title
  
  Aging
  
  Volume: 11 Issue: 6 Pages: 1613-1614
- DOI
  10.18632/aging.101892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08112
[Journal Article] Myeloid HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) Reductase Determines Atherosclerosis by Modulating Migration of Macrophages2018
- Author(s)
  Sakai Kent、Nagashima Shuichi、Wakabayashi Tetsuji、Tumenbayar Bayasgalan、Hayakawa Hiroko、Hayakawa Morisada、Karasawa Tadayoshi、Ohashi Ken、Yamazaki Hisataka、Takei Akihito、Takei Shoko、Yamamuro Daisuke、Takahashi Manabu、Yagyu Hiroaki、Osuga Jun-ichi、Takahashi Masafumi、Tominaga Shin-ichi、Ishibashi Shun
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 11 Pages: 2590-2600
- DOI
  10.1161/atvbaha.118.311664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-16K09789, KAKENHI-PROJECT-17K09865
[Journal Article] Exogenous nanoparticles and endogenous crystalline molecules as danger signals for the?NLRP3 inflammasomes2018
- Author(s)
  Shirasuna Koumei、Karasawa Tadayoshi、Takahashi Masafumi
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 234 Issue: 5 Pages: 5436-5450
- DOI
  10.1002/jcp.27475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-18K08112
[Journal Article] Inflammasome Activation Aggravates Cutaneous Xanthomatosis and Atherosclerosis in ACAT1 (Acyl-CoA Cholesterol Acyltransferase 1) Deficiency in Bone Marrow2018
- Author(s)
  Wakabayashi Tetsuji、Takahashi Manabu、Yamamuro Daisuke、Karasawa Tadayoshi、Takei Akihito、Takei Shoko、Yamazaki Hisataka、Nagashima Shuichi、Ebihara Ken、Takahashi Masafumi、Ishibashi Shun
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 11 Pages: 2576-2589
- DOI
  10.1161/atvbaha.118.311648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08485, KAKENHI-PROJECT-16K09789
[Journal Article] Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease.2018
- Author(s)
  Nakamura J, Watanabe S, Kimura H, Kobayashi M, Karasawa T, Kamata R, Usui-Kawanishi F, Sadatomo A, Mizukami H, Nagi-Miura N, Ohno N, Kasahara T, Minota S, Takahashi M.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 7601-7601
- DOI
  10.1038/s41598-018-25856-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K08485
[Journal Article] Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in MacrophagesHighlights2018
- Author(s)
  Karasawa Tadayoshi、Kawashima Akira、Usui-Kawanishi Fumitake、Watanabe Sachiko、Kimura Hiroaki、Kamata Ryo、Shirasuna Koumei、Koyama Yutaro、Sato-Tomita Ayana、Matsuzaka Takashi、Tomoda Hiroshi、Park Sam-Yong、Shibayama Naoya、Shimano Hitoshi、Kasahara Tadashi、Takahashi Masafumi
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 38 Issue: 4 Pages: 744-756
- DOI
  10.1161/atvbaha.117.310581
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-17K09889, KAKENHI-PUBLICLY-16H01395, KAKENHI-ORGANIZER-26105001, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-18K19724, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-16K09808, KAKENHI-INTERNATIONAL-15K21719
[Journal Article] Interaction of Neutrophils with Macrophages Promotes IL-1β Maturation and Contributes to Hepatic Ischemia?Reperfusion Injury2017
- Author(s)
  Sadatomo Ai、Inoue Yoshiyuki、Ito Homare、Karasawa Tadayoshi、Kimura Hiroaki、Watanabe Sachiko、Mizushina Yoshiko、Nakamura Jun、Kamata Ryo、Kasahara Tadashi、Horie Hisanaga、Sata Naohiro、Takahashi Masafumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 9 Pages: 3306-3315
- DOI
  10.4049/jimmunol.1700717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] Role of NLRP3 Inflammasomes in Atherosclerosis2017
- Author(s)
  Karasawa, T.,Takahashi, M
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 5 Pages: 443-451
- DOI
  10.5551/jat.RV17001
- NAID
  130005631688
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19544, KAKENHI-PROJECT-15K09146
[Journal Article] The crystal-induced activation of NLRP3 inflammasomes in atherosclerosis.2017
- Author(s)
  Karasawa T, Takahashi M.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 37 Issue: 1 Pages: 18-18
- DOI
  10.1186/s41232-017-0050-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction2017
- Author(s)
  Kobayashi Motoi、Usui-Kawanishi Fumitake、Karasawa Tadayoshi、Kimura Hiroaki、Watanabe Sachiko、Mise Nathan、Kayama Fujio、Kasahara Tadashi、Hasebe Naoyuki、Takahashi Masafumi
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 5 Pages: 176676-176676
- DOI
  10.1371/journal.pone.0176676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09889, KAKENHI-PROJECT-15K06912, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19544
[Journal Article] Palmitic acid induces interleukin-1beta secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells.2016
- Author(s)
  Shirasuna K, Takano T, Seno K, Ohtsu A, Karasawa T, Takahashi M, Ohkuchi A, Suzuki H, Matsubara S, Iwata H, Kuwayama T.
- Journal Title
  
  J Reprod Immunol
  
  Volume: 116 Pages: 104-112
- DOI
  10.1016/j.jri.2016.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01395, KAKENHI-PROJECT-15K07783, KAKENHI-PROJECT-15K09146
[Journal Article] Caspse-1 deficiency promotes high-fat diet-induced adipose tissue inflammation and the development of obesity.2016
- Author(s)
  Kimura H, Karasawa T, Usui F, Kawashima A, Endo Y, Kobayashi M, Sadatomo A, Nakamura J, Iwasaki Y, T Yada,Tsutsui H, Kasahara T, Takahashi M.
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 311 Issue: 5 Pages: 881-890
- DOI
  10.1152/ajpendo.00174.2016
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01395, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K19544
[Journal Article] NLRP3 reduces macrophage interleukin-10 production and enhances the susceptibility to doxorubicin-induced cardiotoxicity.2016
- Author(s)
  Kobayashi M, Usui F, Karasawa T, Kawashima A, Kimura H, Mizushina Y, Shirasuna K, Mizukami H, Kasahara T, Hasebe N, Takahashi M.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 26489-26489
- DOI
  10.1038/srep26489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01395, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K09521, KAKENHI-PROJECT-16K19544
[Journal Article] NLRP3 deficiency improves angiotensin II-induced hypertension but not fetal growth restriction during pregnancy.2015
- Author(s)
  Shirasuna K, Karasawa T, Usui F, Kobayashi M, Komada T, Kimura A, Ohkuchi A, Taniguchi S, Takahashi M.
- Journal Title
  
  Endocrinology
  
  Volume: 156 Issue: 11 Pages: 4281-4292
- DOI
  10.1210/en.2015-1408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-24592482, KAKENHI-PROJECT-26461386
[Journal Article] Letter regarding article “Anti-inflammatory and anti-atherogenic effects of the inflammasome NLRP3 inhibitor, arglabin, in ApoE2.Ki mice fed a high fat diet”.2015
- Author(s)
  Karasawa T, Takahashi M.
- Journal Title
  
  Circulation
  
  Volume: 132 Issue: 21
- DOI
  10.1161/circulationaha.115.016070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09146
[Journal Article] Role of NLRP3 inflammasomes for rhabdomyolysis-induced acute kidney injury.2015
- Author(s)
  Komada T, Usui F, Kawashima A, Kimura H, Karasawa T, Inoue Y, Kobayashi M, Mizushina Y, Kasahara T, Taniguchi S, Muto S, Nagata D, Takahashi M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 10901-10901
- DOI
  10.1038/srep10901
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β2015
- Author(s)
  Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 8 Pages: 5065-5077
- DOI
  10.1074/jbc.m114.603217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24590091, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K09146
[Journal Article] Immunoproteasome LMP7 deficiency improves obesity and metabolic disorders.2015
- Author(s)
  Kimura H, Usui F, Karasawa T, Kawashima A, Shirasuna K, Inoue Y, Komada T, Kobayashi M, Mizushina Y, Kasahara T, Suzuki K, Iwasaki Y, Yada T, Caturegli P, Takahashi M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 15883-15883
- DOI
  10.1038/srep15883
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] Oligomerized CARD16 Promotes Caspase-1 Assembly and IL-1β Processing2015
- Author(s)
  Tadayoshi Karasawa, Akira Kawashima, Fumitake Usui, Hiroaki Kimura, Koumei Shirasuna, Yoshiyuki Inoue, Takanori Komada, Motoi Kobayashi, Yoshiko Mizushina, Junji Sagara, Masafumi Takahashi
- Journal Title
  
  FEBS Open Bio
  
  Volume: 5 Issue: 1 Pages: 348-356
- DOI
  10.1016/j.fob.2015.04.011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24890217, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26461386
[Journal Article] RIP140 as a novel therapeutic target in the treatment of atherosclerosis.2015
- Author(s)
  Karasawa T, Takahashi M.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 81 Pages: 136-138
- DOI
  10.1016/j.yjmcc.2015.02.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26860699
[Journal Article] Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm2014
- Author(s)
  Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Yoshimura K, Aoki H, Tsutsui H, Noda T, Sagara J, Taniguchi S, Takahashi M
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 35 Issue: 1 Pages: 127-136
- DOI
  10.1161/atvbaha.114.303763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-26461386, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-26670621
[Journal Article] Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC.2014
- Author(s)
  Shirasuna K, Usui F, Karasawa T, Kimura H, Kawashima A, Mizukami H, Ohkuchi A, Nishimura S, Sagara J, Noda T, Ozawa K, Taniguchi S, Takahashi M
- Journal Title
  
  Nanotoxicology
  
  Volume: 11 Issue: 5 Pages: 1-14
- DOI
  10.3109/17435390.2014.956156
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25850222, KAKENHI-PROJECT-15K08022, KAKENHI-PROJECT-15K09146
[Journal Article] Critical role of caspase-1 in vascular inflammation and development of atherosclerosis in Western diet-fed apolipoprotein E-deficient mice.2012
- Author(s)
  Usui F, Shirasuna K, Kimura H, Tatsumi K, Kawashima A, Karasawa T, Hida S, Sagara J, Taniguchi S, Takahashi M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 425 Issue: 2 Pages: 162-168
- DOI
  10.1016/j.bbrc.2012.07.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590566, KAKENHI-PROJECT-23591359, KAKENHI-PROJECT-24591419, KAKENHI-PROJECT-24790775, KAKENHI-PROJECT-24890217, KAKENHI-PUBLICLY-24117709
[Presentation] カスパーゼ11を介した好中球浸潤の制御と不安定プラーク形成との関連2023
- Author(s)
  唐澤直義、駒田敬則、松村貴由、高橋将文
- Organizer
  第55回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K06875
[Presentation] 脂肪酸によるNLRP3インフラマソームを介した炎症惹起機構と動脈硬化2021
- Author(s)
  唐澤　直義
- Organizer
  第53回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06875
[Presentation] 脂肪酸によるNLRP3インフラマソームを介した炎症惹起機構と動脈硬化2021
- Author(s)
  唐澤　直義
- Organizer
  第53回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] 心血管病におけるインフラマソームの役割2019
- Author(s)
  唐澤　直義, 高橋　将文
- Organizer
  脳心血管抗加齢研究会2019
- Invited
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] 飽和脂肪酸は結晶形成を介して好中球浸潤を誘導する2019
- Author(s)
  唐澤直義、渡邊幸子、笠原忠、高橋将文
- Organizer
  第51回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 動脈硬化の進展におけるNLRP3インフラマソームの役割2019
- Author(s)
  唐澤　直義，高橋　将文
- Organizer
  第40回　日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] Inflammatory crystal-mediated activation of NLRP3 inflammasome in the progression of atherosclerosis2019
- Author(s)
  唐澤　直義
- Organizer
  第51回日本動脈硬化学会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] 動脈硬化の進展におけるNLRP3インフラマソームの役割2019
- Author(s)
  唐澤直義
- Organizer
  第40回日炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] アセトアミノフェン急性肝不全におけるFerroptosisの分子機構2019
- Author(s)
  山田直也、唐澤直義、駒田敬則、木村博昭、伊藤準哉、仲川清隆、桑田浩、原俊太郎、佐久間康成、佐田尚宏、高橋将文
- Organizer
  第33回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 飽和脂肪酸は結晶形成を介して好中球浸潤を引き起こす2019
- Author(s)
  唐澤　直義，駒田敬則, 高橋　将文
- Organizer
  脳心血管抗加齢研究会2019
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] 脂肪細胞分化におけるLMP7の役割．2018
- Author(s)
  木村博昭、唐澤直義、渡邊幸子、鎌田諒、駒田敬則、笠原忠、高橋将文．
- Organizer
  第39回日本肥満学会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 低酸素刺激によるNLRP3インフラマソーム活性化機構の解明2018
- Author(s)
  渡邊幸子、河西文武、木村博昭、唐澤直義、鎌田諒、高橋将文．
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] 飽和脂肪酸の結晶形成を介した炎症惹起機構の解明2018
- Author(s)
  唐澤直義, 渡邊幸子, 木村博昭, 松坂賢, 島野仁, 高橋将文
- Organizer
  第55回　日本臨床分子医学会　学術集会
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] 腸管虚血再灌流障害におけるNLRP3インフラマソームの役割の解明．2018
- Author(s)
  伊藤誉、佐田友藍、井上賢之、鎌田諒、渡邊幸子、唐澤直義、木村博昭、佐田尚宏、高橋将文．
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K08112
[Presentation] コレステロール結晶の炎症惹起のメカニズム2018
- Author(s)
  唐澤直義
- Organizer
  12th Trans Catheter Imaging Forum
- Invited
- Data Source
  KAKENHI-PROJECT-18K08485
[Presentation] ドキソルビシン心筋傷害におけるインフラマソーム構成分子NLRP3の役割．2017
- Author(s)
  高橋将文、小林基、唐澤直義、渡邊幸子、木村博昭．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] Contribution of the immunoproteasome to the inflammatory phenotype observed in obese mice.2017
- Author(s)
  Kimura H, Karasawa T, Watanabe S, Suzuki K, Caturegli P, Takahashi M.
- Organizer
  IMMUNOLOGY2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 飽和脂肪酸は結晶形成を介して好中球浸潤を誘導する．2017
- Author(s)
  唐澤直義、渡邊幸子、木村博昭、高橋将文．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 飽和脂肪酸は結晶形成を介して好中球浸潤を誘導する2017
- Author(s)
  唐澤直義, 渡邊幸子, 木村博昭, 高橋将文
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-16K19544
[Presentation] 肝虚血再灌流障害におけるインフラマソーム非依存性IL-1β産生機構の解明．2017
- Author(s)
  佐田友藍、井上賢之、渡邊幸子、唐澤直義、木村博昭、佐田尚宏、高橋将文．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食誘導による肥満性炎症におけるCaspase-1の役割．2017
- Author(s)
  木村博昭、唐澤直義、渡邊幸子、笠原忠、高橋将文．
- Organizer
  第38回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食による肥満性炎症におけるCaspase-1の役割．2017
- Author(s)
  木村博昭、唐澤直義、岩崎有作、矢田俊彦、高橋将文．
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 高脂肪食誘導型肥満における免疫プロテアソーム（LMP7）の役割．2016
- Author(s)
  木村博昭、唐澤直義、川島晃、臼井文武、笠原忠、鈴木幸一、高橋将文．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂肪酸結晶によるNLRP3インフラマソームを介した炎症惹起機構の解析．2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂肪酸結晶によるNLRP3インフラマソームを介した炎症惹起機構の解析2016
- Author(s)
  唐澤直義, 臼井文武, 川島晃, 木村博昭, 高橋将文
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都市勧業館みやこめっせ（京都府京都市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26860699
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割．2016
- Author(s)
  高橋将文、駒田敬則、臼井文武、唐澤直義、川島晃、木村博昭．
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂肪酸結晶によるNLRP3インフラマソームを介した炎症惹起機構の解析2016
- Author(s)
  唐澤直義, 臼井文武, 川島晃, 木村博昭, 高橋将文
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都市勧業館みやこめっせ（京都）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K19544
[Presentation] メタボリック病態における免疫プロテアソーム欠損の有益な効果．2016
- Author(s)
  木村博昭、臼井文武、唐澤直義、川島晃、笠原忠、鈴木幸一、岩﨑有作、矢田俊彦、高橋将文．
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 飽和脂肪酸によるインフラマソーム活性化機構の解析2016
- Author(s)
  唐澤直義, 臼井文武, 川島晃, 木村博昭, 高橋将文
- Organizer
  第48回日本動脈硬化学会　学術集会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2016-07-15
- Data Source
  KAKENHI-PROJECT-16K19544
[Presentation] 飽和脂肪酸によるインフラマソーム活性化機構の解析．2016
- Author(s)
  唐澤直義、臼井文武、川島晃、木村博昭、高橋将文．
- Organizer
  第48回日本動脈硬化学会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂肪酸の飽和／不飽和バランスの破綻によるインフラマソーム活性化機構の解析2015
- Author(s)
  唐澤直義
- Organizer
  Atherosclerosis & Cardiovascular Research Conference
- Place of Presentation
  ホテルサンルートプラザ新宿（東京都新宿区）
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-26860699
[Presentation] 動脈硬化および大動脈瘤形成におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、木村博昭、唐澤直義、川島晃、谷口俊一郎、高橋将文．
- Organizer
  第26回日本生体防御学会学術総会
- Place of Presentation
  台東区生涯学習センター（東京都台東区）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  高橋将文、駒田敬則、臼井文武、川島晃、唐澤直義、木村博昭．
- Organizer
  心血管抗加齢研究会2015
- Place of Presentation
  梅田スカイビル（大阪市北区）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 横紋筋融解症による急性腎障害におけるNLRP3インフラマソームの役割2015
- Author(s)
  臼井文武、駒田敬則、唐澤直義、川島晃、木村博昭、武藤重明、長田太助、高橋将文．
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] 脂質代謝異常におけるASCの役割2015
- Author(s)
  唐澤直義、木村博昭、臼井文武、川島晃、高橋将文．
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K09146
[Presentation] カスパーゼ１ホモログ分子CARD16 による新規炎症惹起機序の解析2014
- Author(s)
  唐澤　直義，川島　晃，臼井　文武，木村　博昭，高橋　将文
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館（沖縄）
- Year and Date
  2014-07-01
- Data Source
  KAKENHI-PROJECT-24890217
[Presentation] カスパーゼ１ホモログCOPs による炎症制御機構の解析2014
- Author(s)
  唐澤　直義，川島　晃，臼井　文武，木村　博昭，高橋　将文
- Organizer
  第46回日本動脈硬化学会　学術集会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-24890217
[]

1. Takahashi Masafumi (40296108)

# of Collaborated Projects: 12 results

# of Collaborated Products: 60 results
2. 渡邊幸子 (80770619)

# of Collaborated Projects: 6 results

# of Collaborated Products: 26 results
3. 駒田敬則 (90824730)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
4. 木村博昭 (70593622)

# of Collaborated Projects: 5 results

# of Collaborated Products: 39 results
5. 相澤恵美 (80877621)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. Kawanishi Fumitake (50585560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
7. Nakamura Jun (70646314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 松村貴由 (80436485)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. Kawashima Akira (60624913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木幸一 (20206478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 鎌田諒 (60801420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. 佐藤浩二郎 (10372434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIRASUNA Koumei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 谷口俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. バータルジャフ・チントグトフ

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 肥田重明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Karasawa Tadayoshi 唐澤 直義

KARASAWA Tadayoshi 唐澤 直義

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ステロール合成経路による細胞死の制御機構の解明Principal Investigator

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The role of caspase-11-dependent pyroptosis in atherosclerotic lesionPrincipal Investigator

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Neutrophils in inflammatory response induced by lipid crystalsPrincipal Investigator

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The role of inflammasome in prolonged inflammation of atherosclerosisPrincipal Investigator

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Regulation of NLRP3 inflammasome by modulation of lipid metabolismsPrincipal Investigator

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Karasawa Tadayoshi 唐澤直義

KARASAWA Tadayoshi 唐澤直義