midorikawa mitsuharu 緑川光春

… Alternative Names

MIDORIKAWA Mitsuharu 緑川光春

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Researcher Number	60632643
Affiliation (Current)	2025: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都大学, 医学研究科, 教授 2022: 東京女子医科大学, 医学部, 准教授 2020 – 2021: 東京女子医科大学, 医学部, 講師 2017 – 2019: 東京女子医科大学, 医学部, 准講師 2015 – 2016: 同志社大学, 研究開発推進機構, 助教 2013 – 2014: 同志社大学, 高等研究教育機構, 助教 2012 – 2013: 同志社大学, 付置研究所, 助教
Review Section/Research Field	Principal Investigator Neurophysiology / General neuroscience / Basic Section 46010:Neuroscience-general-related / Medium-sized Section 46:Neuroscience and related fields / Neuroscience and related fields / General physiology / Neurophysiology and muscle physiology Except Principal Investigator Neurophysiology / General neuroscience
Keywords	Principal Investigator 開口放出 / イメージング / シナプス / 電気生理学 / 電気生理 / 神経回路発達 / シナプス小胞 / エンドサイトーシス / 神経可塑性 / 神経回路 … More / 脳・神経 / 生理学 / 神経科学 / ライブイメージング / 全反射蛍光顕微鏡 / 国際研究者交流 / 国際研究者交流（ドイツ） / カリックス型シナプス / 膜容量測定法 … More Except Principal Investigator 生理学 / 神経科学 / 神経 / シナプス / イメージング / 軸索 Less

Identification of the developmental change of the synaptic transmission mechanism at the to-be-eliminated synapsePrincipal Investigator
- Principal Investigator
  
  Midorikawa Mitsuharu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  Kyoto University
  Tokyo Women's Medical University
シナプスの選択的強化・除去に伴うシナプス前部の機能的・分子的発達過程の解明Principal Investigator
- Principal Investigator
  
  緑川光春
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Kyoto University
  Tokyo Women's Medical University
Investigating molecular mechanisms of exocytosis by visualizing single fusion eventsPrincipal Investigator
- Principal Investigator
  
  Midorikawa Mitsuharu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Neuroscience and related fields
- Research Institution
  Tokyo Women's Medical University
Super resolution live imaging of synaptic vesicle at neuronal presynaptic terminalPrincipal Investigator
- Principal Investigator
  
  Midorikawa Mitsuharu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Tokyo Women's Medical University
Imaging single synaptic vesicles at CNS presynaptic terminalsPrincipal Investigator
- Principal Investigator
  
  Midorikawa Mitsuharu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Doshisha University
Phsyiology of axons and axon terminals.
- Principal Investigator
  
  Sakaba Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Doshisha University
Application of fluorescent probes to single vesicle analysis
- Principal Investigator
  
  Sakaba Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Doshisha University
Visualizing the mechanism of neurotransmitter releasePrincipal Investigator
- Principal Investigator
  
  MIDORIKAWA Mitsuharu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Doshisha University
神経伝達物質放出部位における開口放出関連タンパク質の動態の解明Principal Investigator
- Principal Investigator
  
  緑川光春
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Doshisha University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Precision Medicine 2021年10月号2021
- Author(s)
  緑川光春
- Total Pages
  100
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-23K21347
[Journal Article] Editorial: Functional and molecular insights of neural circuit adaptation, refinement, and remodeling2023
- Author(s)
  Walter Alexander、Uesaka Naofumi、Midorikawa Mitsuharu
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 17
- DOI
  10.3389/fncel.2023.1213640
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19367, KAKENHI-ORGANIZER-22H05092, KAKENHI-PLANNED-22H05093, KAKENHI-PROJECT-23K21347
[Journal Article] Pathway-specific maturation of presynaptic functions of the somatosensory thalamus.2022
- Author(s)
  Mitsuharu Midorikawa
- Journal Title
  
  Neuroscience Research
  
  Volume: 181 Pages: 1-8
- DOI
  10.1016/j.neures.2022.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19367, KAKENHI-PROJECT-23K21347
[Journal Article] Developmental and activity-dependent modulation of coupling distance between release site and Ca2+ channel.2022
- Author(s)
  Mitsuharu Midorikawa
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: eCollection 2022.
- DOI
  10.3389/fncel.2022.1037721
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19367, KAKENHI-PROJECT-23K21347
[Journal Article] Dysfunction of parvalbumin-expressing cells in the thalamic reticular nucleus induces cortical spike-and-wave discharges and an unconscious state2022
- Author(s)
  Abdelaal Manal S.、Midorikawa Mitsuharu、Suzuki Toru、Kobayashi Kenta、Takata Norio、Miyata Mariko、Mimura Masaru、Tanaka Kenji F.
- Journal Title
  
  Brain Communications
  
  Volume: 4 Issue: 2 Pages: 1-17
- DOI
  10.1093/braincomms/fcac010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06944, KAKENHI-PROJECT-19H03343, KAKENHI-ORGANIZER-20H05914, KAKENHI-PUBLICLY-21H00212, KAKENHI-PROJECT-23K21347
[Journal Article] Distinct functional developments of surviving and eliminated presynaptic terminals2021
- Author(s)
  Midorikawa M, Miyata M.
- Journal Title
  
  Proc Natl Acad Sci U S A .
  
  Volume: 118 Issue: 11
- DOI
  10.1073/pnas.2022423118
- NAID
  120007147680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03548, KAKENHI-ORGANIZER-20H05914
[Journal Article] 中枢神経シナプス前終末における小胞動態の超解像ライブイメージング2019
- Author(s)
  緑川光春
- Journal Title
  
  月刊「細胞 The　CELL」
  
  Volume: 12月号 Pages: 37-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03548
[Journal Article] Real-time imaging of synaptic vesicle exocytosis by total internal reflection fluorescence (TIRF) microscopy.2018
- Author(s)
  Midorikawa M.
- Journal Title
  
  Neurosci Res.
  
  Volume: S0168-0102(17) Pages: 30755-1
- DOI
  10.1016/j.neures.2018.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19466, KAKENHI-PROJECT-17H03548
[Journal Article] Kinetics of Releasable Synaptic Vesicles and Their Plastic Changes at Hippocampal Mossy Fiber Synapses.2017
- Author(s)
  Midorikawa M, Sakaba T.
- Journal Title
  
  Neuron
  
  Volume: 96 Issue: 5 Pages: 1033-1040
- DOI
  10.1016/j.neuron.2017.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19466, KAKENHI-PUBLICLY-17H05753, KAKENHI-PROJECT-15H04261, KAKENHI-PROJECT-17H03548, KAKENHI-PROJECT-15K14321
[Journal Article] Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice.2016
- Author(s)
  Okamoto Y, Lipstein N, Hua Y, Lin KH, Brose N, Sakaba T, Midorikawa M.
- Journal Title
  
  eLife
  
  Volume: 5
- DOI
  10.7554/elife.14643
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04261, KAKENHI-PROJECT-15K18346, KAKENHI-PROJECT-15K14321
[Journal Article] Imaging Exocytosis of Single Synaptic Vesicles at a Fast CNS Presynaptic Terminal.2015
- Author(s)
  Midorikawa M, Sakaba T.
- Journal Title
  
  Neuron
  
  Volume: 88 Issue: 3 Pages: 492-8
- DOI
  10.1016/j.neuron.2015.09.047
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14321, KAKENHI-PROJECT-15K18346, KAKENHI-PUBLICLY-26110720, KAKENHI-PROJECT-15H04261
[Journal Article] Developmental changes in Ca2+ channel subtypes regulating endocytosis at the calyx of Held.2014
- Author(s)
  Midorikawa M, Okamoto Y, Sakaba T
- Journal Title
  
  Journal of Physiology
  
  Volume: 592 Issue: 16 Pages: 3495-3510
- DOI
  10.1113/jphysiol.2014.273243
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300144, KAKENHI-PROJECT-25870896, KAKENHI-PUBLICLY-26110720
[Presentation] Morphological and functional developments of neural circuits at the somatosensory thalamus2024
- Author(s)
  Mitsuharu Midorikawa
- Organizer
  第101回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21347
[Presentation] Morphological and functional developments of neural circuits at the somatosensory thalamus2024
- Author(s)
  Mitsuharu Midorikawa
- Organizer
  第101回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19367
[Presentation] Super-resolution imaging of the presynaptic active zone at the developing somatosensory thalamus.2023
- Author(s)
  Mitsuharu Midorikawa, Hirokazu Sakamoto and Mariko Miyata
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-22K19367
[Presentation] Super-resolution imaging of the presynaptic active zone at the developing somatosensory thalamus2023
- Author(s)
  Mitsuharu Midorikawa, Hirokazu Sakamoto and Mariko Miyata
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-23K21347
[Presentation] Functional and morphological changes of the presynapse at the developing somatosensory thalamus.2022
- Author(s)
  Mitsuharu Midorikawa and Mariko Miyata
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-22K19367
[Presentation] Functional and morphological changes of the presynapse at the developing somatosensory thalamus.2022
- Author(s)
  16)Mitsuharu Midorikawa and Mariko Miyata.
- Organizer
  NEURO2022.
- Data Source
  KAKENHI-PROJECT-23K21347
[Presentation] Development of presynaptic functions at surviving and eliminated synapses in the somatosensory thalamus2021
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  第44回日本神経科学大会第1回 CJK 国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21347
[Presentation] Sensory input dependent and independent development of presynaptic transmitter release mechanisms at lemniscal fiber terminals in the somatosensory thalamus2021
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-17H03548
[Presentation] Direct measurements of transmitter release kinetics at lemniscal fiber terminals in the somatosensory thalamus.2020
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17H03548
[Presentation] Presynaptic properties at lemniscal fiber terminals in the somatosensory thalamus2019
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  第9回アジア・オセアニア生理学会連合 (FAOPS) 2019年大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19466
[Presentation] Direct measurements of transmitter release from lemniscal fiber terminals in the somatosensory thalamus.2019
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H03548
[Presentation] Presynaptic properties at lemniscal fiber terminals in the somatosensory thalamus2019
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  第9回アジア・オセアニア生理学会連合 (FAOPS) 2019年大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03548
[Presentation] Investigating presynaptic properties of afferent fibers in the somatosensory thalamus.2018
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  Core-to-Core program “Nanobiology of neural plasticity based on optical nanoscopy”
- Data Source
  KAKENHI-PROJECT-17K19466
[Presentation] Measuring dynamics of releasable synaptic vesicles at hippocampal mossy fiber boutons.2018
- Author(s)
  緑川光春、坂場武史
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03548
[Presentation] 中枢神経シナプス前終末における単一シナプス小胞動態の可視化2018
- Author(s)
  緑川光春、坂場武史
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17H03548
[Presentation] Measuring dynamics of releasable synaptic vesicles and their plastic changes at hippocampal mossy fiber boutons.2018
- Author(s)
  Mitsuharu Midorikawa and Takeshi Sakaba
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K19466
[Presentation] Investigating presynaptic properties of afferent fibers in the somatosensory thalamus.2018
- Author(s)
  緑川光春、宮田麻理子
- Organizer
  Core-to-Core program “Nanobiology of neural plasticity based on optical nanoscopy”
- Data Source
  KAKENHI-PROJECT-17H03548
[Presentation] Measuring dynamics of releasable synaptic vesicles at hippocampal mossy fiber boutons.2018
- Author(s)
  緑川光春、坂場武史
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19466
[Presentation] Live cell imaging of single synaptic vesicles at mammalian CNS presynaptic terminals.2017
- Author(s)
  Midorikawa M
- Organizer
  第94回日本生理学会大会シンポジウム
- Place of Presentation
  アクトシティ浜松(静岡県・浜松市)
- Year and Date
  2017-03-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18346
[Presentation] Calmodulin-Munc 13-1 signaling regulates the coordinated uptake of synaptic vesicle membrane and protein at the calyx of Held2016
- Author(s)
  Yuji Okamoto, Takeshi Sakaba, and Mitsuharu Midorikawa
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K18346
[Presentation] Dynamics of single synaptic vesicles at the presynaptic terminals of mammalian central synapses2016
- Author(s)
  Mitsuharu Midorikawa and Takeshi Sakaba
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18346
[Presentation] Visualizing kinetics of single synaptic vesicles at the calyx-type presynaptic terminal.2015
- Author(s)
  Mitsuharu Midorikawa and Takeshi Sakaba
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K18346
[Presentation] ラットカリックス型シナプスにおける開口放出とエンドサイトーシスの電気生理学的、光学的測定2014
- Author(s)
  岡本悠志、緑川光春、坂場武史
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Data Source
  KAKENHI-PROJECT-25870896
[Presentation] ラットカリックス型シナプスにおけるCa2+チャネルとエンドサイトーシスとの関係2013
- Author(s)
  緑川光春
- Organizer
  第９０回日本生理学会大会
- Place of Presentation
  タワーホール船堀　（東京）
- Data Source
  KAKENHI-PROJECT-24800073
[Presentation] Visualizing exocytosis of single synaptic vesicles at the calyx-type presynaptic terminal
- Author(s)
  Mitsuharu Midorikawa and Takeshi Sakaba
- Organizer
  第120回日本解剖学会総会・全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21 – 2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-25870896
[Presentation] Measurements of synaptic exo-endocytosis by electrophysiological and optical tecnique at the rat calyx of Held synapse
- Author(s)
  Mitsuharu Midorikawa, Yuji Okamoto and Takeshi Sakaba
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25870896

1. Sakaba Takeshi (80609511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. KAWAGUCHI Shinya (00378530)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 高田則雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

midorikawa mitsuharu 緑川 光春

MIDORIKAWA Mitsuharu 緑川 光春

Research Projects

Research Products

Co-Researchers

Identification of the developmental change of the synaptic transmission mechanism at the to-be-eliminated synapsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シナプスの選択的強化・除去に伴うシナプス前部の機能的・分子的発達過程の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigating molecular mechanisms of exocytosis by visualizing single fusion eventsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Super resolution live imaging of synaptic vesicle at neuronal presynaptic terminalPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Imaging single synaptic vesicles at CNS presynaptic terminalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Phsyiology of axons and axon terminals.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of fluorescent probes to single vesicle analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Visualizing the mechanism of neurotransmitter releasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経伝達物質放出部位における開口放出関連タンパク質の動態の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Precision Medicine 2021年10月号2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Editorial: Functional and molecular insights of neural circuit adaptation, refinement, and remodeling2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathway-specific maturation of presynaptic functions of the somatosensory thalamus.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developmental and activity-dependent modulation of coupling distance between release site and Ca2+ channel.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dysfunction of parvalbumin-expressing cells in the thalamic reticular nucleus induces cortical spike-and-wave discharges and an unconscious state2022

midorikawa mitsuharu 緑川光春

MIDORIKAWA Mitsuharu 緑川光春

[Journal Article] 中枢神経シナプス前終末における小胞動態の超解像ライブイメージング2019