Kuroda Shinji 黒田新士

… Alternative Names

KURODA Shinji 黒田新士

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Researcher Number	60633758
Other IDs
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 岡山大学, 大学病院, 講師 2016 – 2021: 岡山大学, 大学病院, 助教 2013 – 2015: 岡山大学, 医学部, 客員研究員 2012: 岡山大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / General surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Laboratory medicine
Keywords	Principal Investigator 胃癌 / HER2 / 金ナノ粒子 / ウイルス療法 / 大腸がん / 抗腫瘍免疫 / 酪酸 / 腸内細菌 / 腫瘍融解ウイルス / 組織内不均一性 … More / バイスタンダー効果 / 組織不均一性 / 抗体薬物複合体 / 免疫療法 / 免疫チェックポイント阻害 / アブスコパル効果 / 腫瘍浸潤リンパ球 / 免疫チェックポイント / 免疫原性細胞死 / 複合免疫療法 / 免疫チェックポイント阻害剤 / 抗PD-1抗体 / 腫瘍融解アデノウイルス / トラスツヅマブ / トラスツズマブ抵抗性 / トラスツズマブ / 腫瘍選択的増殖型アデノウイルス製剤 / 全身投与 / ナノテクノロジー / 陽イオンリポソーム / 腫瘍選択的増殖型アデノウイルス … More Except Principal Investigator トランスレーショナル・リサーチ / トランスレーショナルリサーチ / 医療・福祉 / 細胞・組織 / 遺伝子 / 癌 / 腫瘍関連マクロファージ / 腹腔内遊離癌細胞 / 膵癌 / 腫瘍微小環境 / 抗癌剤抵抗性 / マクロファージ / 癌微小環境 / 腹膜播種 / 消化器癌 Less

腸内細菌と次世代がん治療用ウイルスのクロストークによる新たな大腸がん治療開発研究Principal Investigator
- Principal Investigator
  
  黒田新士
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University
Immune molecular mechanism for enhancing antitumor potency of a next-generation oncolytic virus by pre-immunization
- Principal Investigator
  
  藤原俊義
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University
Gold nanoparticle-conjugated antibody-drug conjugates for HER2-positive gastric cancer with heterogeneityPrincipal Investigator
- Principal Investigator
  
  Kuroda Shinji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University
Development of a next-generation viral agent targeting immunosuppression by crosstalk in the pancreatic cancer microenvironment
- Principal Investigator
  
  Fujiwara Toshiyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Okayama University
Combination of telomerase-specific oncolytic adenovirus and immune checkpoint inhibitorPrincipal Investigator
- Principal Investigator
  
  Kuroda Shinji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Okayama University
Analysis for intraperitoneal cancer microenvironment to elucidate the biological mechanism of peritoneal metastasis of gastrointestinal cancer
- Principal Investigator
  
  Shunsuke Kagawa
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
Novel HER2-targeted gold nanoparticles for gastric cancerPrincipal Investigator
- Principal Investigator
  
  Kuroda Shinji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University
Development of systemically-deliverable oncolytic adenovirusPrincipal Investigator
- Principal Investigator
  
  KURODA Shinji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Digestive surgery
- Research Institution
  Okayama University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Dual antiplatelet therapy inhibits neutrophil extracellular traps to reduce liver micrometastases of intrahepatic cholangiocarcinoma2023
- Author(s)
  Yoshimoto Masashi、Kagawa Shunsuke、Kajioka Hiroki、Taniguchi Atsuki、Kuroda Shinji、Kikuchi Satoru、Kakiuchi Yoshihiko、Yagi Tomohiko、Nogi Shohei、Teraishi Fuminori、Shigeyasu Kunitoshi、Yoshida Ryuichi、Umeda Yuzo、Noma Kazuhiro、Tazawa Hiroshi、Fujiwara Toshiyoshi
- Journal Title
  
  Cancer Letters
  
  Volume: 567 Pages: 216260-216260
- DOI
  10.1016/j.canlet.2023.216260
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08775, KAKENHI-PROJECT-23K24407
[Journal Article] Oncolytic virus-mediated reducing of myeloid-derived suppressor cells enhances the efficacy of PD-L1 blockade in gemcitabine-resistant pancreatic cancer2023
- Author(s)
  Kajiwara Y, Tazawa H, Yamada S, Kanaya N, Fushimi T, Kikuchi S, Kuroda S, Ohara T, Noma K, Yoshida R, Umeda Y, Urata Y, Kagawa S, Fujiwara T
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 72 Issue: 5 Pages: 1285-1300
- DOI
  10.1007/s00262-022-03334-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07219, KAKENHI-PROJECT-22K08775, KAKENHI-PROJECT-23K19511, KAKENHI-PROJECT-22K08873, KAKENHI-PROJECT-23K24407
[Journal Article] Intraperitoneal administration of p53-armed oncolytic adenovirus inhibits peritoneal metastasis of diffuse-type gastric cancer cells2023
- Author(s)
  Hori N, Tazawa H, Li Y, Okura T, Kikuchi S, Kuroda S, Ohara T, Noma K, Nishizaki M, Urata Y, Kagawa S, Fujiwara T
- Journal Title
  
  Anticancer Res
  
  Volume: 43 Issue: 11 Pages: 4809-4821
- DOI
  10.21873/anticanres.16678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07219, KAKENHI-PROJECT-23K24407
[Journal Article] p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells2023
- Author(s)
  Tamura S, Tazawa H, Hori N, Li Y, Yamada M, Kikuchi S, Kuroda S, Urata Y, Kagawa S, Fujiwara T
- Journal Title
  
  PLoS One
  
  Volume: 18 Issue: 11 Pages: e0294491-e0294491
- DOI
  10.1371/journal.pone.0294491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19511, KAKENHI-PROJECT-21K07219, KAKENHI-PROJECT-23K24407
[Journal Article] Exosomes as a drug delivery tool for cancer therapy: a new era for existing drugs and oncolytic viruses2023
- Author(s)
  Kakiuchi Y, Kuroda S, Kanaya N, Kagawa S, Tazawa H, Fujiwara T
- Journal Title
  
  Expert Opin Ther Targets
  
  Volume: 27 Issue: 9 Pages: 807-816
- DOI
  10.1080/14728222.2023.2259102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07219, KAKENHI-PROJECT-23K24407
[Journal Article] Overexpression of Adenovirus E1A Reverses Transforming Growth Factor-β-induced Epithelial-mesenchymal Transition in Human Esophageal Cancer Cells2022
- Author(s)
  Masuda T, Tazawa H, Hashimoto Y, Ieda T, Kikuchi S, Kuroda S, Noma K, Urata Y, Kagawa S, Fujiwara T
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 76 Issue: 2 Pages: 203-215
- DOI
  10.18926/AMO/63425
- URL
  https://ousar.lib.okayama-u.ac.jp/63425
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07219, KAKENHI-PROJECT-23K24407
[Journal Article] Modulation of cancer-associated fibroblasts by oncolytic adenovirus-mediated p53 gene therapy overcomes peritoneal metastasis of gastric cancer2022
- Author(s)
  Ogawa T, Kikuchi S, Tabuchi M, Mitsui E, Une Y, Tazawa H, Kuroda S, Noma K, Ohara T, Kagawa S, Urata Y, Fujiwara T
- Journal Title
  
  Mol Ther Oncolytics
  
  Volume: 25 Pages: 249-261
- DOI
  10.1016/j.omto.2022.04.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07219, KAKENHI-PROJECT-23K24407, KAKENHI-PROJECT-22K08873
[Journal Article] Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer2022
- Author(s)
  Araki H, Tazawa H, Kanaya N, Kajiwara Y, Yamada M, Hashimoto M, Kikuchi S, Kuroda S, Yoshida R, Umeda Y, Urata Y, Kagawa S, Fujiwara T
- Journal Title
  
  Mol Ther Oncolytics
  
  Volume: 27 Pages: 3-13
- DOI
  10.1016/j.omto.2022.09.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07219, KAKENHI-PROJECT-22K08775, KAKENHI-PROJECT-23K24407, KAKENHI-PROJECT-22K08873
[Journal Article] Local oncolytic adenovirotherapy produces an abscopal effect via tumor-derived extracellular vesicles2021
- Author(s)
  Yoshihiko Kakiuchi, Shinji Kuroda, Nobuhiko Kanaya, Kento Kumon, Tomoko Tsumura, Masashi Hashimoto, Chiaki Yagi, Ryoma Sugimoto, Yuki Hamada, Satoru Kikuchi, Masahiko Nishizaki, Shunsuke Kagawa, Hiroshi Tazawa, Yasuo Urata, Toshiyoshi Fujiwara
- Journal Title
  
  Molecular Therapy
  
  Volume: 29 Issue: 10 Pages: 2925-2930
- DOI
  10.1016/j.ymthe.2021.05.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17617, KAKENHI-PROJECT-19H03731
[Journal Article] Extracellular vesicles shed from gastric cancer mediate protumor macrophage differentiation2021
- Author(s)
  Ito Atene、Kagawa Shunsuke、Sakamoto Shuichi、Kuwada Kazuya、Kajioka Hiroki、Yoshimoto Masashi、Kikuchi Satoru、Kuroda Shinji、Yoshida Ryuichi、Tazawa Hiroshi、Fujiwara Toshiyoshi
- Journal Title
  
  BMC Cancer
  
  Volume: 21 Issue: 1 Pages: 102-114
- DOI
  10.1186/s12885-021-07816-6
- NAID
  120006980466
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08679, KAKENHI-PROJECT-19H03731
[Journal Article] Targeting neutrophil extracellular traps with thrombomodulin prevents pancreatic cancer metastasis2021
- Author(s)
  Kajioka Hiroki、Kagawa Shunsuke、Ito Atene、Yoshimoto Masashi、Sakamoto Shuichi、Kikuchi Satoru、Kuroda Shinji、Yoshida Ryuichi、Umeda Yuzo、Noma Kazuhiro、Tazawa Hiroshi、Fujiwara Toshiyoshi
- Journal Title
  
  Cancer Letters
  
  Volume: 497 Pages: 1-13
- DOI
  10.1016/j.canlet.2020.10.015
- NAID
  120007188794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-18K08679, KAKENHI-PROJECT-19H03731
[Journal Article] Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer.2020
- Author(s)
  Koujima T., Tazawa H., Ieda T., Araki H., Fushimi T., Shoji R., Kuroda S., Kikuchi S., Yoshida R., Umeda Y., Teraishi F., Urata Y., Mizuguchi H., Fujiwara T.
- Journal Title
  
  Mol. Ther. Oncolysis.
  
  Volume: 17 Pages: 107-117
- DOI
  10.1016/j.omto.2020.03.016
- NAID
  120006869596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00863, KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-19H03731, KAKENHI-PROJECT-20H00664
[Journal Article] Boosting Replication and Penetration of Oncolytic Adenovirus by Paclitaxel Eradicate Peritoneal Metastasis of Gastric Cancer.2020
- Author(s)
  Ishikawa W, Kikuchi S, Ogawa T, Tabuchi M, Tazawa H, Kuroda S, Noma K, Nishizaki M, Kagawa S, Urata Y, Fujiwara T.
- Journal Title
  
  Molecular Therapy-Oncolytics
  
  Volume: 18 Pages: 262-271
- DOI
  10.1016/j.omto.2020.06.021
- NAID
  120006892937
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03731
[Journal Article] Immune Modulation by Telomerase-Specific Oncolytic Adenovirus Synergistically Enhances Antitumor Efficacy with Anti-PD1 Antibody.2020
- Author(s)
  Kanaya N., Kuroda S., Kakiuchi Y., Kumon K., Tsumura T., Hashimoto M., Morihiro T., Kubota T., Aoyama K., Kikuchi S., Nishizaki M., Kagawa S., Tazawa H., Mizuguchi H., Urata Y., Fujiwara T.
- Journal Title
  
  Mol. Ther.
  
  Volume: 28 Issue: 3 Pages: 794-804
- DOI
  10.1016/j.ymthe.2020.01.003
- NAID
  120006952300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H00863, KAKENHI-PROJECT-19H03731, KAKENHI-PROJECT-20H00664
[Journal Article] PD-L1 expression combined with microsatellite instability/CD8+ tumor infiltrating lymphocytes as a useful prognostic biomarker in gastric cancer.2019
- Author(s)
  Morihiro T, Kuroda S, Kanaya N, Kakiuchi Y, Kubota T, Aoyama K, Tanaka T, Kikuchi S, Nagasaka T, Nishizaki M, Kagawa S, Tazawa H, Fujiwara T.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 4633-4633
- DOI
  10.1038/s41598-019-41177-2
- NAID
  120006777516
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03731
[Journal Article] Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment?colorectal cancer network2019
- Author(s)
  Ieda Takeshi、Tazawa Hiroshi、Okabayashi Hiroki、Yano Shuya、Shigeyasu Kunitoshi、Kuroda Shinji、Ohara Toshiaki、Noma Kazuhiro、Kishimoto Hiroyuki、Nishizaki Masahiko、Kagawa Shunsuke、Shirakawa Yasuhiro、Saitou Takashi、Imamura Takeshi、Fujiwara Toshiyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 16378-16378
- DOI
  10.1038/s41598-019-52816-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12218, KAKENHI-PROJECT-19H03731, KAKENHI-PROJECT-17K10589, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-18K08679
[Journal Article] Outcome of Radiation Monotherapy for High-risk Patients with Stage I Esophageal Cancer2017
- Author(s)
  Shirakawa Y, Noma K, Maeda N, Tanabe S, Kuroda S, Kagawa S, Katsui K, Katayama N, Kanazawa S, Fujiwara T.
- Journal Title
  
  Acta Medica Okayama
  
  Volume: 71 Issue: 2 Pages: 127-133
- DOI
  10.18926/AMO/54981
- NAID
  120006026999
- URL
  https://ousar.lib.okayama-u.ac.jp/54981
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15193
[Journal Article] Double-flap technique as an antireflux procedure in esophagogastrostomy after proximal gastrectomy2016
- Author(s)
  Kuroda S, Nishizaki M, Kikuchi S, Noma K, Tanabe S, Kagawa S, Shirakawa Y, Fujiwara T
- Journal Title
  
  J Am Coll Surg
  
  Volume: 223 Issue: 2 Pages: e7-e13
- DOI
  10.1016/j.jamcollsurg.2016.04.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461978, KAKENHI-PROJECT-15K15193
[Journal Article] Training system for laparoscopy-assisted distal gastrectomy.2016
- Author(s)
  Kuroda S, Kikuchi S, Hori N, Sakamoto S, Kagawa T, Watanabe M, Kubota T, Kuwada K, Ishida M, Kishimoto H, Uno F, Nishizaki M, Kagawa S, Fujiwara T
- Journal Title
  
  Surgery today
  
  Volume: 印刷中 Issue: 7 Pages: 802-809
- DOI
  10.1007/s00595-016-1439-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15193
[Journal Article] Nonexposure laparoscopic and endoscopic cooperative surgery (closed laparoscopic and endoscopic cooperative surgery) for gastric submucosal tumor2016
- Author(s)
  Kikuchi S, Nishizaki M, Kuroda S, Tanabe S, Noma K, Kagawa S, Shirakawa Y, Kato H, Okada H, Fujiwara T
- Journal Title
  
  Gastric Cancer
  
  Volume: 20 Issue: 3 Pages: 553-557
- DOI
  10.1007/s10120-016-0641-1
- NAID
  40021185849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461978, KAKENHI-PROJECT-15K15193
[Presentation] Telomelysin as an immunotherapy agent sensitizing gastrointestinal tumors to anti-PD-1 antibody2018
- Author(s)
  Nobuhiko Kanaya, Shinji Kuroda, Kento Kumon, Yoshihiko Kakiuchi, Toshiaki Morihiro, Tetsushi Kubota, Hiroshi Tazawa, Satoru Kikuchi, Masahiko Nishizaki, Shunsuke Kagawa, Yasuo Urata, Toshiyoshi Fujiwara
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] Immunogenic Telomelysin synergizes with anti-PD-1 antibody in gastrointestinal tumors to anti-PD-1 antibody2018
- Author(s)
  Nobuhiko Kanaya, Shinji Kuroda, Yoshihiko Kakiuchi, Toshiaki Morihiro, Tetsushi Kubota, Satoru Kikuchi, Masahiko Nishizaki, Yasuo Urata, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] Immunogenic potential of Telomelysin sensitizing gastrointestinal tumors to anti-PD-1 antibody2018
- Author(s)
  Nobuhiko Kanaya, Shinji Kuroda, Yoshihiko Kakiuchi, Toshiaki Morihiro, Tetsushi Kubota, Satoru Kikuchi, Masahiko Nishizaki, Yasuo Urata, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara
- Organizer
  第24回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] 腫瘍内リンパ球浸潤を誘導するテロメライシンと抗PD-1抗体を用いた新規複合免疫療法の開発2018
- Author(s)
  金谷信彦，黒田新士，公文剣斗，垣内慶彦，森廣俊昭，菊地覚次，西崎正彦，浦田泰生，田澤大，香川俊輔，藤原俊義
- Organizer
  第31回日本バイオセラピィ学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] テロメラーゼ活性依存的腫瘍融解アデノウイルスと抗PD-1抗体による新たな複合免疫療法の開発2018
- Author(s)
  金谷信彦，黒田新士，垣内慶彦，森廣俊昭，菊地覚次，西崎正彦，浦田泰生，田澤大，香川俊輔，藤原俊義
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] Telomelysin-induced immunogenic cell death synergizes with anti-PD-1 antibody in non-immunogenic gastrointestinal tumors2018
- Author(s)
  Nobuhiko Kanaya, Shinji Kuroda, Toshiaki Morihiro, Yoshihiko Kakiuchi, Tetsushi Kubota, Satoru Kikuchi, Masahiko Nishizaki, Yasuo Urata, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara
- Organizer
  AACR 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] 腫瘍選択的融解アデノウイルス療法が腫瘍内リンパ球浸潤を増加させ，抗PD-1抗体の感受性を増強させる2018
- Author(s)
  金谷信彦，黒田新士，垣内慶彦，森廣俊昭，菊地覚次，田澤大，浦田泰生，西崎正彦，香川俊輔，藤原俊義
- Organizer
  第39回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] Combination of PD-L1 expression and microsatellite instability status is a useful and attractive prognostic factor in gastric cancer2017
- Author(s)
  Toshiaki Morihiro, Shinji Kuroda, Nobuhiko Kanaya, Toshiyoshi Fujiwara, et al.
- Organizer
  AACR Anunal Meeting 2017
- Place of Presentation
  Washington DC
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] Attractive ability of telomerase-specific oncolytic adenovirus as an immunogenic drug2017
- Author(s)
  Nobuhiko Kanaya, Shinji Kuroda, Toshiaki Morihiro, Tetsushi Kubota, Hiroshi Tazawa, Satoru Kikuchi, Masahiko Nishizaki, Yasuo Urata, Shunsuke Kagawa, Toshiyoshi Fujiwara
- Organizer
  第23回日本遺伝子細胞治療学会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] Potential of telomerase-specific oncolytic adenovirus as an immunogenic drug producing synergy with anti-PD-1 therapy2017
- Author(s)
  Nobuhiko Kanaya, Shinji Kuroda, Toshiaki Morihiro, Tetsushi Kubota, Hiroshi Tazawa, Satoru Kikuchi, Masahiko Nishizaki, Shunsuke Kagawa, Yasuo Urata, Toshiyoshi Fujiwara
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] テロメラーゼ依存的腫瘍選択的融解アデノウイルス製剤の免疫原性薬剤としての可能性と抗PD-1抗体との併用療法の有用性2017
- Author(s)
  金谷信彦，黒田新士，垣内慶彦，森廣俊昭，久保田哲史，田澤大，菊地覚次，西崎正彦，香川俊輔，藤原俊義
- Organizer
  第30回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-16K19893
[Presentation] Tumor associated macrophages promote malignant phenotypes of disseminated human gastric cancer cells in intraperitoneal cancer immune microenvironment2017
- Author(s)
  Shuichi Sakamoto, Shunsuke Kagawa, Kazuya Kuwada, Atene Ito, Tetsuya Kagawa, Satoru Kikuchi, Shinji Kuroda, Ryuichi Yoshida, Hiroshi Tazawa, Toshiyoshi Fujiwara
- Organizer
  American Association for Cancer Research, Annual Meeting 2017
- Place of Presentation
  ワシントンDC, 米国
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15193
[Presentation] Clinical implications of fluorescence-emitting virus guided peritoneal cytology in gastrointestinal cancer.2016
- Author(s)
  Kagawa S, Watanabe M, Kuwata K, Sakamoto S, Shigeyasu K, Tazawa H, Kuroda S, Kikuchi S, Yoshida R, Nishizaki M, Kishimoto H, Nagasaka T, Fujiwara T.
- Organizer
  The 19th International Congress of Cytology: ICC2016
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-05-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15193
[Presentation] Intraperitoneal macrophages in patients with gastric cancer are polarized to promote malignant phenotypes of disseminated cancer cells.2016
- Author(s)
  渡辺めぐみ, 香川俊輔, 桒田和也, 坂本修一, 菊地覚次, 黒田新士, 岸本浩行, 西崎正彦, 田澤大, 藤原俊義
- Organizer
  第71回　日本消化器外科学会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15K15193
[Presentation] Novel HER2-targeted gold nanoparticles; integration of antibody and nanotechnology2016
- Author(s)
  Tetsushi Kubota, Shinji Kuroda, Toshiaki Morihiro, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2016
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870390
[Presentation] Virus-guided fluorescent imaging of pancreatic cancer cells in the peritoneal cavity for an insight into roles of tumor-associated macrophage2016
- Author(s)
  Kazuya Kuwada, Shunsuke Kagawa, Megumi Watanabe, Shuichi Sakamoto, Tetsuya Kagawa, Satoru Kikuchi, Shinji Kuroda, Ryuichi Yoshida, Hiroshi Tazawa and Toshiyoshi Fujiwara.
- Organizer
  The 22nd Annual Meeting of Japan Society of Gene and Cell Therapy
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2016-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15193
[Presentation] 蛍光ウイルスによる腹腔内の腫瘍関連マクロファージと膵癌細胞の関連性の解析2016
- Author(s)
  桑田和也, 香川俊輔, 坂本修一, 渡邉めぐみ, 香川哲也, 菊地覚次, 黒田新士, 吉田龍一, 浦田泰生, 田澤大, 藤原俊義
- Organizer
  第75回　日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K15193
[Presentation] 金ナノ粒子を用いたHER2標的抗体療法2016
- Author(s)
  久保田哲史，黒田新士，森廣俊昭，田澤大，香川俊輔，藤原俊義
- Organizer
  第37回癌免疫外科研究会
- Place of Presentation
  川越プリンスホテル，埼玉
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26870390
[Presentation] HER2-targeted gold nanoparticles produce potent antitumor effects on human gastric cancer cells2015
- Author(s)
  Tetsushi Kubota, Shinji Kuroda, Katsuyuki Aoyama, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara
- Organizer
  American Association for Cancer Research (AACR) Annual Meeting 2015
- Place of Presentation
  Philadelphia, Pennsylvania, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870390
[Presentation] 金ナノ粒子を用いた新規HER2標的抗体療法2015
- Author(s)
  久保田哲史，黒田新士，森廣俊昭，青山克幸，田澤大，香川俊輔，藤原俊義
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場，名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26870390
[Presentation] 金ナノ粒子を用いたHER2標的抗体療法2015
- Author(s)
  久保田哲史，黒田新士，青山克幸，森廣俊昭，田澤大，藤原俊義
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル，東京
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26870390
[Presentation] Development of systemically-deliverable telomerase-specific oncolytic adenovirus2014
- Author(s)
  Katsuyuki Aoyama, Shinji Kuroda, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara
- Organizer
  American Association for Cancer Research
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-24890130
[Presentation] 金ナノ粒子を用いたHER2標的抗体療法
- Author(s)
  久保田哲史，黒田新士，青山克幸，森廣俊昭，田澤大，藤原俊義
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル、東京
- Year and Date
  2015-07-02 – 2015-07-03
- Data Source
  KAKENHI-PROJECT-26870390
[Presentation] HER2-targeted gold nanoparticles produce potent antitumor effects on human gastric cancer cells
- Author(s)
  Tetsushi Kubota, Shinji Kuroda, Katsuyuki Aoyama, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara.
- Organizer
  American Association for Cancer Research (AACR)
- Place of Presentation
  Philadelphia, Pennsylvania, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-26870390

1. FUJIWARA Toshiyoshi (00304303)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
2. TAZAWA Hiroshi (90415513)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
3. 吉田龍一 (80534768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. Shunsuke Kagawa (00362971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. NAGASAKA Takeshi (30452569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 垣内慶彦 (70868356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 金谷信彦 (50985223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUBOTA Tetsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. YAGI Takahito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. UMEDA Yuzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 水口裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 重安邦俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 吉田一博

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 西崎正彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 齋藤卓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuroda Shinji 黒田 新士

KURODA Shinji 黒田 新士

Research Projects

Research Products

Co-Researchers

腸内細菌と次世代がん治療用ウイルスのクロストークによる新たな大腸がん治療開発研究Principal Investigator

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Immune molecular mechanism for enhancing antitumor potency of a next-generation oncolytic virus by pre-immunization

Principal Investigator

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Gold nanoparticle-conjugated antibody-drug conjugates for HER2-positive gastric cancer with heterogeneityPrincipal Investigator

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Development of a next-generation viral agent targeting immunosuppression by crosstalk in the pancreatic cancer microenvironment

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Combination of telomerase-specific oncolytic adenovirus and immune checkpoint inhibitorPrincipal Investigator

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Analysis for intraperitoneal cancer microenvironment to elucidate the biological mechanism of peritoneal metastasis of gastrointestinal cancer

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Novel HER2-targeted gold nanoparticles for gastric cancerPrincipal Investigator

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Development of systemically-deliverable oncolytic adenovirusPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Dual antiplatelet therapy inhibits neutrophil extracellular traps to reduce liver micrometastases of intrahepatic cholangiocarcinoma2023

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[Journal Article] Oncolytic virus-mediated reducing of myeloid-derived suppressor cells enhances the efficacy of PD-L1 blockade in gemcitabine-resistant pancreatic cancer2023

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[Journal Article] Intraperitoneal administration of p53-armed oncolytic adenovirus inhibits peritoneal metastasis of diffuse-type gastric cancer cells2023

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[Journal Article] p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells2023

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[Journal Article] Exosomes as a drug delivery tool for cancer therapy: a new era for existing drugs and oncolytic viruses2023

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[Journal Article] Overexpression of Adenovirus E1A Reverses Transforming Growth Factor-β-induced Epithelial-mesenchymal Transition in Human Esophageal Cancer Cells2022

Author(s)

Kuroda Shinji 黒田新士

KURODA Shinji 黒田新士