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Nishiyama Shuhei  西山 修平

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NISHIYAMA Shuhei  西山 修平

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Researcher Number 60636017
Other IDs
Affiliation (Current) 2025: 東北大学, 大学病院, 助教
2025: 東北大学, 医学系研究科, 大学院非常勤講師
Affiliation (based on the past Project Information) *help 2025: 東北大学, 大学病院, 助教
2014 – 2018: 東北大学, 大学病院, 助教
2012 – 2013: 東北大学, 大学病院, 医員
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords
Principal Investigator
視神経脊髄炎 / アストロサイト / 脳神経疾患 / 補体受容体 / NKT細胞 / NK細胞 / 免疫学 / 炎症性脱髄性疾患 / 抗アクアポリン4抗体 / ARPC4 … More / CRMP5 / 仮足 / アクアポリン4 / 脳脊髄液 / バイオマーカー / アクアポリン4抗体 / 補体依存性細胞傷害 / 補体非依存性細胞傷害 / アクアポリン4 / 補体非介在性傷害 / 補体介在性傷害 / 補体非介在性障害 / 補体介在性障害 Less
  • Research Projects

    (4 results)
  • Research Products

    (24 results)
  •  非典型的NK/NKT細胞を介した視神経脊髄炎の再発病態解明と新規治療開発Principal Investigator

    • Principal Investigator
      西山 修平
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Tohoku University
  •  Establishment of diagnosis and prognostic factors in cerebrospinal fluid based on the condition of inflammatory central nervous diseasePrincipal Investigator

    • Principal Investigator
      Nishiyama Shuhei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Molecular mechanism of astrocytic damage via endocytosis of AQP4 in Neuromyelitis opticaPrincipal Investigator

    • Principal Investigator
      Nishiyama Shuhei
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  The effect of NMO-IgG and complement against primary human astrocytes in culture.Principal Investigator

    • Principal Investigator
      NISHIYAMA Shuhei
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Neurology
    • Research Institution
      Tohoku University

All 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] 視神経脊髄炎(NMO)におけるアストロサイトの役割2013

    • Author(s)
      西山修平、三須建郎、中島一郎、藤原一男
    • Journal Title

      神経内科

      Volume: 79(2) Pages: 257-61

    • Data Source
      KAKENHI-PROJECT-24890017
  • [Journal Article] 視神経脊髄炎(NMO)におけるアストロサイトの役割2013

    • Author(s)
      西山修平、三須建郎、中島一郎、藤原一男
    • Journal Title

      神経内科

      Volume: 第79巻第2号 Pages: 257-261

    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] Early pathological features in Fingolimod-associated PML with mild IRIS.2018

    • Author(s)
      Nishiyama S, Misu T, Shishido-Hara Y, Nakamichi K, Saijo M, Takai Y, Kuroda H, Nakashima I, Fujihara K, Aoki M
    • Organizer
      日本神経学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K19504
  • [Presentation] CSF biomarkers for NMOSD2018

    • Author(s)
      Shuhei Nishiyama
    • Organizer
      PACTRIMS 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19504
  • [Presentation] Cerebrospilnal fluid-Actin related protein 2/3 complex subunit 4 as an astrocytic foot process damage marker of aquaporin-4-IgG positive neuromyelitis optica spectrum disorders.2017

    • Author(s)
      Shuhei Nishiyama, Tatsuro Misu, Ichiro Nakashima, Douglas Kazutoshi Sato, Kimihiko Kaneko, Ryo Ogawa, Hirohiko Ono, Kazuhiro Kurosawa, Yoshiki Takai, Toshiyuki Takahashi, Hiroshi Kuroda, Kazuo Fujihara, Masashi Aoki
    • Organizer
      MSParis 2017 (ECTRIMS/ACTRIMS joint meeting)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19504
  • [Presentation] Cerebrospilnal fluid-Actin related protein 2/3 complex subunit 4 as an astrocytic foot process damage marker of aquaporin-4-IgG positive neuromyelitis optica spectrum disorders.2017

    • Author(s)
      Shuhei Nishiyama, Tatsuro Misu, Ichiro Nakashima, Douglas Kazutoshi Sato, Kimihiko Kaneko, Ryo Ogawa, Hirohiko Ono, Kazuhiro Kurosawa, Yoshiki Takai, Toshiyuki Takahashi, Hiroshi Kuroda, Kazuo Fujihara, Masashi Aoki
    • Organizer
      World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19504
  • [Presentation] Cerebrospilnal fluid-Actin related protein 2/3 complex subunit 4 as an astrocytic foot process damage marker of aquaporin-4-IgG positive neuromyelitis optica spectrum disorders.2017

    • Author(s)
      Shuhei Nishiyama, Tatsuro Misu, Ichiro Nakashima, Douglas Kazutoshi Sato, Kimihiko Kaneko, Ryo Ogawa, Hirohiko Ono, Kazuhiro Kurosawa, Yoshiki Takai, Toshiyuki Takahashi, Hiroshi Kuroda, Kazuo Fujihara, Masashi Aoki
    • Organizer
      PACTRIMS 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19504
  • [Presentation] Elevated cerebrospinal fluid -CRMP5 as a biomarker of damage to astrocyte foot process and growth corn in AQP4-IgG-seropositve NMOSD2016

    • Author(s)
      Shuhei Nishiyama, Tatsuro Misu, Ichiro Nakashima, Toshiyuki Takahashi, Kazuo Fujihara, Masashi Aoki
    • Organizer
      PACTRIMS (The Pan-Asian Committee for Treatment and Research in Multiple Sclerosis) 2016
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2016-10-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19504
  • [Presentation] Elevated cerebrospinal fluid -CRMP5 as a biomarker of damage to astrocyte foot process and growth corn in AQP4-IgG-seropositve NMOSD2016

    • Author(s)
      Shuhei Nishiyama, Tatsuro Misu, Ichiro Nakashima, Toshiyuki Takahashi, Kazuo Fujihara, Masashi Aoki
    • Organizer
      ECTRIMS (The European Committee for Treatment and Research in Multiple Sclerosis) 2016
    • Place of Presentation
      London, UK
    • Year and Date
      2016-09-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19504
  • [Presentation] 炎症性脱髄性疾患の診断・予後における髄液中GFAP濃度有用性の多施設横断的検討-サブ解析結果-2015

    • Author(s)
      西山修平、三須建郎、清水優子、横山和正、景山卓、高井良樹、高野里菜、高橋利幸、藤盛寿一、佐藤滋、中島一郎、糸山泰人、藤原一男、青木正志
    • Organizer
      日本神経学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26860656
  • [Presentation] The usefulness of cerebrospinal fluid lactic dehydrogenation enzyme in the evaluation of disease activity in inflammatory demyelinating diseases.2015

    • Author(s)
      Shuhei Nishiyama, Tatsuro Misu, Rina Takano, Yoshiki Takai, Toshiyuki Takahashi, Ichiro Nakashima, Kazuo Fujihara, Masashi Aoki
    • Organizer
      ECTRIMS 2015
    • Place of Presentation
      バルセロナ、スペイン
    • Year and Date
      2015-10-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860656
  • [Presentation] 炎症性脱髄性疾患の疾患活動性評価における脳脊髄液中LDH値有用性の検討2015

    • Author(s)
      西山修平、三須建郎、高野里菜、高井良樹、高橋利幸、中島一郎、藤原一男、青木正志
    • Organizer
      日本神経学会学術集会
    • Place of Presentation
      朱鷺メッセ(新潟)
    • Year and Date
      2015-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860656
  • [Presentation] A multicenter, cross-sectional study of the usefulness of CSF-GFAP in the diagnosis and the prognosis of inflammatory CNS diseases.2014

    • Author(s)
      S. Nishiyama, T. Misu, Y. Simizu, K. Yokoyama, T. Kageyama, Y. Takai, R. Takano, T. Takahashi, J. Fujimori, S. Sato, I. Nakashima, Y. Itoyama, K. Fujihara, M. Aoki
    • Organizer
      American Academy of Neurology
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2014-04-28
    • Data Source
      KAKENHI-PROJECT-26860656
  • [Presentation] Subanalysis of a multicentric cross-sectional study of CSF-GFAP in the diagnosis of inflammatory demyelinating diseases.2014

    • Author(s)
      S. Nishiyama, T. Misu, Y. Simizu, K. Yokoyama, T. Kageyama, Y. Takai, R. Takano, T. Takahashi, J. Fujimori, S. Sato, I. Nakashima, Y. Itoyama, K. Fujihara, M. Aoki
    • Organizer
      MS Boston 2014
    • Place of Presentation
      Boston, USA
    • Year and Date
      2014-09-14
    • Data Source
      KAKENHI-PROJECT-26860656
  • [Presentation] A multicentric cross-sectional study of the usefulness of CSF-GFAP in the diagnosis and the prognosis of inflammatory demyelinating diseases2013

    • Author(s)
      S. Nishiyama, T. Misu, Y. Simizu, K. Yokoyama, T. Kageyama, Y. Takai, R. Takano, T. Takahashi, J. Fujimori, S. Sato, I. Nakashima, Y. Itoyama, K. Fujihara, M. Aoki
    • Organizer
      29th ECTRIMS
    • Place of Presentation
      デンマーク・コペンハーゲン
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] 炎症性脱髄性疾患の診断・予後における髄液中GFAP濃度有用性の多施設横断的検討2013

    • Author(s)
      西山修平、三須建郎、清水優子、横山和正、景山卓、高井良樹、高野里菜、高橋利幸、藤盛寿一、佐藤滋、中島一郎、糸山泰人、藤原一男、青木正志
    • Organizer
      第25回日本神経免疫学会学術集会
    • Place of Presentation
      下関
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] 炎症性脱髄性疾患の診断・予後における脳脊髄液中GFAP 濃度有用性の多施設横断的検討2013

    • Author(s)
      西山修平、三須建郎、清水優子、横山和正、景山卓、高井良樹、高野里菜、高橋利幸、藤盛寿一、佐藤滋、中島一郎、糸山泰人、藤原一男、青木正志
    • Organizer
      第25回日本神経免疫学会学術集会
    • Place of Presentation
      下関
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] 炎症性脱髄性疾患の診断・予後における髄液中GFAP濃度有用性の多施設横断的検討2013

    • Author(s)
      西山修平、三須建郎、清水優子、横山和正、景山卓、高井良樹、高野里菜、高橋利幸、藤盛寿一、佐藤滋、中島一郎、糸山泰人、藤原一男、青木正志
    • Organizer
      第54回日本神経学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] A multicentric cross-sectional study of the usefulness of CSF-GFAP in the diagnosis and the prognosis of inflammatory demyelinating diseases2013

    • Author(s)
      S. Nishiyama, T. Misu, Y. Simizu, K. Yokoyama, T. Kageyama, Y. Takai, R. Takano, T. Takahashi, J. Fujimori, S. Sato, I. Nakashima, Y. Itoyama, K. Fujihara, M. Aoki
    • Organizer
      PACTRIMS 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] A multicenter, cross-sectional study of the usefulness of CSF-GFAP in the diagnosis and the prognosis of inflammatory CNS diseases.2013

    • Author(s)
      S. Nishiyama, T. Misu, Y. Simizu, K. Yokoyama, T. Kageyama, Y. Takai, R. Takano, T. Takahashi, J. Fujimori, S. Sato, I. Nakashima, Y. Itoyama, K. Fujihara, M. Aoki
    • Organizer
      PACTRIMS 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] A multicentric cross-sectional study of the usefulness of cerebrospinal fluid-glial fibrillary acidic protein (CSF-GFAP) in the diagnosis and prognosis of inflammatory demyelinating diseases2013

    • Author(s)
      S. Nishiyama, T. Misu, Y. Simizu, K. Yokoyama, T. Kageyama, Y. Takai, R. Takano, T. Takahashi, J. Fujimori, S. Sato, I. Nakashima, Y. Itoyama, K. Fujihara, M. Aoki
    • Organizer
      29th ECTRIMS
    • Place of Presentation
      デンマーク・コペンハーゲン
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] 炎症性脱髄性疾患の診断・予後における脳脊髄液中GFAP 濃度有用性の多施設横断的検討2013

    • Author(s)
      西山修平、三須建郎、清水優子、横山和正、景山卓、高井良樹、高野里菜、高橋利幸、藤盛寿一、佐藤滋、中島一郎、糸山泰人、藤原一男、青木正志
    • Organizer
      第54回日本神経学会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-24890017
  • [Presentation] AQP4 Immunology in NMOSD.

    • Author(s)
      Shuhei Nishiyama
    • Organizer
      PACTRIMS 2014
    • Place of Presentation
      台北、台湾
    • Year and Date
      2014-11-06 – 2014-11-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26860656
  • [Presentation] CSF markers in AQP4/MOG-IgG-positive NMOSD.

    • Author(s)
      Shuhei Nishiyama, Tatsuro Misu, Yuko Simizu, Kazumasa Yokoyama, Takashi Kageyama, Yoshiki Takai, Rina Takano, Toshiyuki Takahashi, Jun-ichi Fujimori, Sigeru Sato, Ichiro Nakashima, Yasuto Itoyama, Kazuo Fujihara, Masashi Aoki
    • Organizer
      Charcot Foundation Annual Meeting
    • Place of Presentation
      Baveno, Italy
    • Year and Date
      2014-11-26 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-26860656

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