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Ishii Sumiyasu  石井 角保

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Sumiyasu Ishii  石井 角保

石井 角保  イシイ スミヤス

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Researcher Number 60638112
Other IDs
Affiliation (Current) 2025: 新潟県立看護大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 新潟県立看護大学, 看護学部, 教授
2021 – 2022: 群馬大学, 大学院医学系研究科, 講師
2015 – 2017: 群馬大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 54040:Metabolism and endocrinology-related
Except Principal Investigator
Endocrinology
Keywords
Principal Investigator
HDAC3 / 甲状腺ホルモン不応症 / 甲状腺 / 小脳 / 甲状腺ホルモン
Except Principal Investigator
心脳血管障害誘発因子 / モデル動物 / KCNJ5変異 / 腫瘍発生 / 高血圧症 / 原発性アルドステロン症
  • Research Projects

    (3 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (10 People)
  •  HDAC3によるゲノム三次元区画化制御に着目した甲状腺ホルモン不応症の病態解明Principal Investigator

    • Principal Investigator
      石井 角保
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Niigata College of Nursing
  •  Functional analysis of HDAC3 in hypothyroidism and study of genome compartmentalization by a new method.Principal Investigator

    • Principal Investigator
      Sumiyasu Ishii
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Niigata College of Nursing
      Gunma University
  •  Insight into mechanisims undelying Primary aldosteronism

    • Principal Investigator
      Masanobu Yamada
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      Gunma University

All 2023 2022 2021 2016

All Journal Article Presentation

  • [Journal Article] Online Physiology Practice with Team-Based Learning During the COVID-19 Pandemic2023

    • Author(s)
      Fujiwara Yuki、Amano Izuki、Ishii Sumiyasu、Kishi Mikiko、Koibuchi Noriyuki
    • Journal Title

      Advances in Medical Education and Practice

      Volume: Volume 14 Pages: 1435-1443

    • DOI

      10.2147/amep.s415257

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08569, KAKENHI-PROJECT-21K17266
  • [Journal Article] 甲状腺ホルモン不応症の診断と治療2022

    • Author(s)
      石井角保
    • Journal Title

      Medical Practice

      Volume: 39 Pages: 61-65

    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Journal Article] The neurotoxic effect of lactational PFOS exposure on cerebellar functional development in male mice2022

    • Author(s)
      Ninomiya A, Mshaty A, Haijima A, Yajima H, Kokubo M, Khairinisa MA, Ariyani W, Fujiwara Y, Ishii S, Hosoi N, Hirai H, Amano I, Koibuchi N.
    • Journal Title

      Food Chem Toxicol

      Volume: 159:112751 Pages: 112751-112751

    • DOI

      10.1016/j.fct.2021.112751

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07103, KAKENHI-PROJECT-18H03379, KAKENHI-PROJECT-20K06906, KAKENHI-PROJECT-21K08569, KAKENHI-PROJECT-21K17266, KAKENHI-PROJECT-22KJ0445
  • [Journal Article] Long-term depression?inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor2022

    • Author(s)
      Ninomiya Ayane、Amano Izuki、Kokubo Michifumi、Takatsuru Yusuke、Ishii Sumiyasu、Hirai Hirokazu、Hosoi Nobutake、Koibuchi Noriyuki
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 45

    • DOI

      10.1073/pnas.2210645119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06906, KAKENHI-PROJECT-21K08569
  • [Journal Article] Histone Deacetylase 3 Inhibitor Alleviates Cerebellar Defects in Perinatal Hypothyroid Mice by Stimulating Histone Acetylation and Transcription at Thyroid Hormone-Responsive Gene Loci2022

    • Author(s)
      Susetyo Alvin、Ishii Sumiyasu、Fujiwara Yuki、Amano Izuki、Koibuchi Noriyuki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 14 Pages: 7869-7869

    • DOI

      10.3390/ijms23147869

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Journal Article] COUP-TFII in Kidneys, from Embryos to Sick Adults2022

    • Author(s)
      Ishii Sumiyasu、Koibuchi Noriyuki
    • Journal Title

      Diagnostics

      Volume: 12 Issue: 5 Pages: 1181-1181

    • DOI

      10.3390/diagnostics12051181

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Journal Article] The Role of Thyroid Hormone in the Regulation of Cerebellar Development2021

    • Author(s)
      Ishii Sumiyasu、Amano Izuki、Koibuchi Noriyuki
    • Journal Title

      Endocrinology and Metabolism

      Volume: 36 Issue: 4 Pages: 703-716

    • DOI

      10.3803/enm.2021.1150

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16486, KAKENHI-PROJECT-18H03379, KAKENHI-PROJECT-21K08569, KAKENHI-PROJECT-21K15340
  • [Journal Article] The Role of Histone Deacetylase 3 Complex in Nuclear Hormone Receptor Action2021

    • Author(s)
      Ishii Sumiyasu
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 17 Pages: 9138-9138

    • DOI

      10.3390/ijms22179138

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Journal Article] GNAS mutations in adrenal aldosterone-producing adenomas2016

    • Author(s)
      Nakajima Y, Okamura T, Horiguchi K, Gohko T, Miyamoto T, Satoh T, Ozawa A, Ishii S, Yamada E, Hashimoto K, Okada S, Takata D, Horiguchi J, Yamada M.
    • Journal Title

      Endocr J.

      Volume: 63 Pages: 199-204

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04852
  • [Presentation] 「甲状腺ホルモン不応症の手引き」の刊行2023

    • Author(s)
      石井角保、山田正信
    • Organizer
      第66回 日本甲状腺学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] 変異甲状腺ホルモン受容体を発現させたマウスプルキンエ細胞では、長期抑圧誘発刺激は長期増強を惹起する2023

    • Author(s)
      二ノ宮彩音、天野出月、小久保倫文、高鶴裕介、石井角保、平井宏和、細井延武、鯉淵典之
    • Organizer
      第96回 日本内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] The indispensable role of thyroid hormone during development in the maintenance of cerebellar function in adulthood2023

    • Author(s)
      Ayane Ninomiya, Izuki Amano, Michifumi Kokubo, Yusuke Takatsuru, Sumiyasu Ishii, Hirokazu Hirai, Nobutake Hosoi, Noriyuki Koibuchi
    • Organizer
      第66回 日本甲状腺学会学術集会 国際分子甲状腺シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] 甲状腺ホルモン不応症とTSH産生PitNET2023

    • Author(s)
      山田正信、堀口和彦、石井角保
    • Organizer
      第33回臨床内分泌代謝Update
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] 甲状腺ホルモン不応症診療の手引きの作成2022

    • Author(s)
      石井角保、山田正信
    • Organizer
      第65回日本甲状腺学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] ヒストン脱アセチル化酵素3阻害剤による周産期甲状腺機能低下症マウスの治療研究2022

    • Author(s)
      石井角保、Alvin Susetyo、天野出月、鯉淵典之
    • Organizer
      第95回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] Histone deacetylase 3 inhibition mitigates hypothyroidism-induced cerebellar developmental defects in mice2022

    • Author(s)
      Alvin Susetyo, Sumiyasu Ishii, Izuki Amano, Noriyuki Koibuchi
    • Organizer
      第99回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] ヒストン脱アセチル化酵素3阻害剤は生体内で標的遺伝子のヒストンをアセチル化し甲状腺機能低下症による小脳発達障害を軽減する2022

    • Author(s)
      石井角保、Alvin Susetyo、天野出月、鯉淵典之
    • Organizer
      第65回日本甲状腺学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] Functional analysis of a lncRNA THRB-AS22022

    • Author(s)
      石井角保、鯉淵典之
    • Organizer
      第99回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] 臨床重要課題 甲状腺ホルモン不応症の診断基準ならびに治療指針の作成2021

    • Author(s)
      石井角保、山田正信
    • Organizer
      第64回日本甲状腺学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] ベータ型甲状腺ホルモン受容体遺伝子逆鎖由来long non-coding RNAのTHP-1細胞における機能解析2021

    • Author(s)
      石井角保、堀口和彦、中島康代、小澤厚志、渋沢信行、佐藤哲郎、天野出月、宮崎航、山田正信、鯉淵典之
    • Organizer
      第94回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] The role of histone deacetylase 3 (HDAC3) in cerebellar developmental defects induced by hypothyroidism2021

    • Author(s)
      Alvin Susetyo, Sumiyasu Ishii, Izuki Amano, Noriyuki Koibuchi
    • Organizer
      第94回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] ヒストン脱アセチル化酵素3阻害剤投与により周産期甲状腺機能低下症マウスの運動協調障害が軽減される2021

    • Author(s)
      石井角保、Alvin Susetyo、天野出月、鯉淵典之
    • Organizer
      第64回日本甲状腺学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08569
  • [Presentation] The role of histone deacetylase 3 in motor coordination defects induced by perinatal hypothyroidism2021

    • Author(s)
      Alvin Susetyo, Sumiyasu Ishii, Izuki Amano, Noriyuki Koibuchi
    • Organizer
      11th International Symposium of the Society for Research on the Cerebellum and Ataxias
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08569
  • 1.  Masanobu Yamada (90261833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  小澤 厚志 (10573496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  堀口 和彦 (10737943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  佐藤 哲郎 (40302484)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  桑原 正靖 (40334130)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  中島 康代 (70707017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  渋沢 信行 (90396622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  鯉淵 典之 (80234681)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HOSOI Nobutake
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  天野 出月
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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