MURAKOSHI HAYATO 村越勇人

Researcher Number	60646123
Other IDs
Affiliation (based on the past Project Information) *help	2019: 熊本大学, ヒトレトロウイルス学共同研究センター, 特任准教授 2016 – 2018: 熊本大学, エイズ学研究センター, 特任講師 2015: 熊本大学, エイズ学研究センター, 特任助教 2013 – 2014: 熊本大学, エイズ学研究センター, 産学官連携研究員
Review Section/Research Field	Principal Investigator Infectious disease medicine / Virology
Keywords	Principal Investigator HLA / 細胞傷害性T細胞 / HIV / CTL / HIV-1

Mechanism for control of HIV-1 by cytotoxic T lymphocytePrincipal Investigator
- Principal Investigator
  
  Murakoshi Hayato
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kumamoto University
Study on HIV-1-specific cytotoxic T lymphocytes responsible for AIDS progression in HIV-1-infected individualsPrincipal Investigator
- Principal Investigator
  
  MURAKOSHI HAYATO
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kumamoto University
Study on HIV-1-specific cytotoxic T cells effectively controlling HIV-1Principal Investigator
- Principal Investigator
  
  MURAKOSHI HAYATO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University

All 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Contribution of Proteasome-Catalyzed Peptide cis-splicing to Viral Targeting by CD8 + T Cells in HIV-1 Infection2019
- Author(s)
  Paes W, Leonov G, Partridge T, Chikata T, Murakoshi H, Frangou A, Brackenridge S, Nicastri A, Smith AG, Learn GH , Li Y, Parker R, Oka S, Pellegrino P, Williams I, Haynes BF, McMichael AJ, Shaw GM, Hahn BH, Takiguchi M, Ternette N, Borrow P
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 116 Issue: 49 Pages: 24748-24759
- DOI
  10.1073/pnas.1911622116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10021
[Journal Article] Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication2019
- Author(s)
  Murakoshi H*, Kuse N*, Akahoshi T, Zhang Y, Chikata T, Borghan MA, Gatanaga H, Oka S, Sakai K, Takiguchi M (* equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 1
- DOI
  10.1128/jvi.01480-18
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens2019
- Author(s)
  Zou C*, Murakoshi H*, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M (*Equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 7
- DOI
  10.1128/jvi.02142-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02, a protective allele, using an immunopeptidomics approach2019
- Author(s)
  Chikata T, Paes W, Akahoshi T, Partridge T, Murakoshi H, Gatanaga H, Ternette N, Oka S, Borrow P, Takiguchi M
- Journal Title
  
  Journal of Virology
  
  Volume: 93 Issue: 17
- DOI
  10.1128/jvi.00634-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181
[Journal Article] CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication2018
- Author(s)
  Murakoshi H*, Zou C*, Kuse N, Akahoshi T, Chikata T, Gatanaga H, Oka S, Hanke T, Takiguchi M (* equal contribution)
- Journal Title
  
  Retrovirology
  
  Volume: 15 Issue: 1 Pages: 46-46
- DOI
  10.1186/s12977-018-0429-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-18K16181, KAKENHI-PROJECT-15H02658
[Journal Article] Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control2018
- Author(s)
  Murakoshi H, Koyanagi M, Akahoshi T, Chikata T, Kuse N, Gatanaga H, Rowland-Jones SL, Oka S, Takiguchi M
- Journal Title
  
  EBioMedicine
  
  Volume: 36 Pages: 103-112
- DOI
  10.1016/j.ebiom.2018.09.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10021
[Journal Article] Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype2017
- Author(s)
  Chikata Takayuki、Murakoshi Hayato、Koyanagi Madoka、Honda Kazutaka、Gatanaga Hiroyuki、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 216 Issue: 11 Pages: 1415-1424
- DOI
  10.1093/infdis/jix483
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08129, KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-16K19614
[Journal Article] Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017
- Author(s)
  Murakoshi H, Koyanagi M, Chikata T, Rahman MA, Kuse N, Sakai K, Gatanaga H, Oka S, Takiguchi M.
- Journal Title
  
  J Virol.
  
  Volume: 91(4) Issue: 4
- DOI
  10.1128/jvi.02082-16
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19614
[Journal Article] Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines2017
- Author(s)
  Nicola Borthwick, Zhansong Lin, Tomohiro Akahoshi, Anuska Llano, Sandra Silva-Arrieta, Tina Ahmed, Lucy Dorrell, Christian Brander, Hayato Murakoshi, Masafumi Takiguchi, Tomas Hanke
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 4 Pages: e0176418-e0176418
- DOI
  10.1371/journal.pone.0176418
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-16K19160
[Journal Article] HLA Class I-Mediated HIV-1 Control in Vietnamese Infected with HIV-1 Subtype A/E2017
- Author(s)
  Chikata Takayuki、Tran Giang Van、Murakoshi Hayato、Akahoshi Tomohiro、Qi Ying、Naranbhai Vivek、Kuse Nozomi、Tamura Yoshiko、Koyanagi Madoka、Sakai Sachiko、et al.
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 5
- DOI
  10.1128/jvi.01749-17
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08129, KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160, KAKENHI-PROJECT-16K19614
[Journal Article] Novel conserved-region T-cell mosaic vaccine with high global HIV-1 coverage is recognized by protective responses in untreated infection2016
- Author(s)
  Beatrice Ondondo, Hayato Murakoshi, Genevieve Clutton, Sultan Abdul-Jawad, Edmund G.-T. Wee, Hiroyuki Gatanaga, Shinichi Oka, Andrew J. McMichael, Masafumi Takiguchi, Bette Korber and Tomas Hanke
- Journal Title
  
  Molecular Therapy
  
  Volume: 24 Issue: 4 Pages: 832-842
- DOI
  10.1038/mt.2016.3
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588
[Journal Article] A strong association of HLA-associated Pol and Gag mutations with clinical parameters2016
- Author(s)
  Giang Van Tran,* Takayuki Chikata,* Jonathan M. Carson, Hayato Murakoshi, Dung Hoai Nguyen, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Sachiko Sakai, Kyle Cobarrubias, Shinichi Oka, Zabrina L. Brumme, Kinh Van Nguyen, and Masafumi Takiguchi, (*Equal contribution)
- Journal Title
  
  AIDS
  
  Volume: 30 Issue: 5 Pages: 681-689
- DOI
  10.1097/qad.0000000000000969
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-15H02658
[Journal Article] Different Effects of Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutations2015
- Author(s)
  Nozomi Kuse*, Mohammad Arif Rahman*, Hayato Murakoshi*, Giang Van Tran, Takayuki Chikata, Madoka Koyanagi, Kinh Van Nguyen, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi, (*Equal contribution)
- Journal Title
  
  Journal of Virology
  
  Volume: 89 Issue: 14 Pages: 7363-7372
- DOI
  10.1128/jvi.00974-15
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-15H02658
[Journal Article] Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes2015
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Naoki Ishizuka, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Journal Title
  
  Journal of Virology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870550
[Journal Article] Host-Specific Adaptation of HIV-1 Subtype Bin the Japanese Population2014
- Author(s)
  Takayuki Chikata, Jonathan M. Carlson, Yoshiko Tamura, Mohamed Ali Borghan, Takuya Naruto, Masao Hashimoto, Hayato Murakoshi, Anh Q. Le, Simon Mallal, Mina John, Hiroyuki Gatanaga, Shinichi Oka, Zabrina L. Brumme, Masafumi Takiguchi
- Journal Title
  
  Journal of Virology
  
  Volume: 88巻 Issue: 9 Pages: 4764-4775
- DOI
  10.1128/jvi.00147-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04376, KAKENHI-PROJECT-25870550, KAKENHI-PROJECT-26293240
[Journal Article] Raltegravir and elvitegravir-resistance mutation E92Q affects HLA-B*40:02-restricted HIV-1-specific CTL recognition2014
- Author(s)
  Mohammad Arif Rahman, Nozomi Kuse, Hayato Murakoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Microbes and Infection
  
  Volume: 印刷中 Issue: 5 Pages: 434-438
- DOI
  10.1016/j.micinf.2014.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870550
[Journal Article] Naturally selected rilpivirine-resistant HIV-1 variants by host cellular immunity2013
- Author(s)
  Hiroyuki Gatanaga, Hayato Murakoshi, Atsuko Hachiya, Tsunefusa Hayashida, Takayuki Chikata, Hirotaka Ode, Kiyoto Tsuchiya, Wataru Sugiura, Masafumi Takiguchi, and Shinichi Oka
- Journal Title
  
  Clinical Infectious Disease
  
  Volume: 57 Issue: 7 Pages: 1051-1055
- DOI
  10.1093/cid/cit430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870550
[Journal Article] Identification of cross-clade CTL epitopes in HIV-1 clade A/E-infected individuals by using the clade B overlapping peptides2013
- Author(s)
  Koji Watanabe*, Hayato Murakoshi*, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi (*Equal contribution)
- Journal Title
  
  Microbes and Infection
  
  Volume: 15 Issue: 13 Pages: 874-886
- DOI
  10.1016/j.micinf.2013.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870550, KAKENHI-PROJECT-25870552
[Presentation] A critical role of T-cell escape mutations associated with a detrimental allele HLA-C*15:05 in poor clinical outcome of Vietnamese individuals infected with HIV-1 subtype A/E.2020
- Author(s)
  Hayato Murakoshi, Takayuki Chikata, Tomohiro Akahoshi, Chengcheng Zou, Giang Van Tran, Trung Vu Nguyen, Kinh Van Nguyen, Nozomi Kuse, Masafumi Takiguchi
- Organizer
  22nd International Conference on Emerging Infectious Diseases in the Pacific Rim AIDS Panel
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02 using an immunopeptidomics approach2019
- Author(s)
  Takayuki Chikata, Wayne Paes, Thomas Partridge, Hayato Murakoshi, Nicola Ternette, Persephone Borrow, Masafumi Takiguchi
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] HIV-1 clade A/E感染者の病態に及ぼすdetrimental allele HLA-C*15:05関連T細胞逃避変異の影響2019
- Author(s)
  村越勇人, 近田貴敬, 赤星智寛, 滝口雅文
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Different mechanisms for accumulation of Gag280 mutations between HIV-1 subtype A/E and subtype B infection2019
- Author(s)
  Yu Zhang, Nozomi Kuse, Hayato Murakoshi, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02 using an immunopeptidomics approach2019
- Author(s)
  Takayuki Chikata, Wayne Paes, Thomas Partridge, Hayato Murakoshi, Nicola Ternette, Persephone Borrow, Masafumi Takiguchi
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Selection of GagRI8 mutants by HLA-B*52:01-restricted GagRI8-specific CTLs controlling HIV-1 in HIV-1-infected Japanese individuals2018
- Author(s)
  Yu Zhang, Nozomi Kuse, Hayato Murakoshi, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Masafumi Takiguchi
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] HLA-B*35:01保有者におけるHIV-1感染促進の機序の解明2018
- Author(s)
  村越勇人, 小柳円, 赤星智寛, 近田貴敬, 久世望, 潟永博之, 岡慎一, 滝口雅文
- Organizer
  第32回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Generation of HIV-1 polymorphism via coevolution of multiple HIV-1-specific T cells with HIV-12018
- Author(s)
  Tomohiro Akahoshi, Hiroyuki Gatanaga, Nozomi Kuse, Takayuki Chikata, Hayato Murakoshi, Naoki Ishizuka, Shinichi Oka, Masafumi Takiguchi
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Broad recognition of circulating HIV-1 by HIV-1-specific CTLs with strong ability to suppress HIV-1 replication2018
- Author(s)
  Nozomi Kuse, Hayato Murakoshi, Tomohiro Akahoshi, Yu Zhang, Takayuki Chikata, Mohamed Ali Borghan, Hiroyuki Gatanaga, Shinichi Oka, Keiko Sakai, Masafumi Takiguchi
- Organizer
  HIVR4P 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Control of HIV-1 by CD8+ T cells specific for epitopes of conserved mosaic vaccine immunogens2018
- Author(s)
  Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomas Hanke, Masafumi Takiguchi
- Organizer
  HIVR4P 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] 強いHIV-1増殖抑制能を有したCTLによる変異HIV-1の認識2017
- Author(s)
  村越勇人, 久世望, 赤星智寛, 近田貴敬, Zhang Yu, 潟永博之, 岡　慎一, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Control of HIV-1 by CTLs restricted by an HLA-B*52:01-HLA-C*12:02 protective haplotype2017
- Author(s)
  Hayato Murakoshi, Takayuki Chikata, Madoka Koyanagi, Kazutaka Honda, Lin Zhansong, Tomohiro Akahoshi, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Impact of a single escape mutation selected by HLA-A*24:02-restricted CD8+ T cells on HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptation2017
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Nozomi Kuse, and Masafumi Takiguchi
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Impact of a single escape mutation selected by HLA-A*24:02-restricted CD8+ T cells on HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptation2017
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Katherine L James, Yoshiko Tamura, Nozomi Kuse, Xiaoming Sun, Hiroyuki Gatanaga, Sarah L Rowland-Jones,　Shinichi Oka, and Masafumi Takiguchi
- Organizer
  IAS 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10021
[Presentation] Impaired Effect of HLA-A*24:02-Associated Mutation on HLA-B*35:01-Associated HIV-1 Control2016
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Katherine L James, Nozomi Kuse, Yoshiko Tamura, Sarah L Rowland-Jones, Shinichi Oka, Hiroyuki Gatanaga, and Masafumi Takiguchi
- Organizer
  HIVR4P 2016
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] ベトナム人HIV-1サブタイプA/E感染者コホートにおけるエイズ病態進行に関与するHLAアリルの探索2016
- Author(s)
  近田貴敬, Giang Van Tran, 村越勇人, 田村美子, 赤星智寛, 久世望, 阪井恵子, 小柳円, Kinh Van Nguyen, 滝口雅文
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島県鹿児島市（かごしま県民交流センター）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] Impact of a Single HLA-A*24:02-associated Escape Mutation on HLA-B*35:01-associated HIV-1 Control and T cell Adaptation2016
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Katherine L James, Yoshiko Tamura, Nozomi Kuse, Xiaoming Sun, Hiroyuki Gatanaga, Sarah L Rowland-Jones,　Shinichi Oka, and Masafumi Takiguchi
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島県鹿児島市（かごしま県民交流センター）
- Year and Date
  2016-11-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] HIV-1と特異的CTLの相互適応2016
- Author(s)
  赤星智寛, 端本昌夫, 村越勇人, 近田貴敬, 田村美子, 潟永博之, 岡慎一, 滝口雅文
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島県鹿児島市（かごしま県民交流センター）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] HIV-1-specific CD8+ T cells responsible for rapid AIDS progression in HIV-1-infected Japanese individuals carrying HLA-B*35:012015
- Author(s)
  Hayato Murakoshi, Madoka Koyanagi, Tomohiro Akahoshi, Takayuki Chikata, and Masafumi Takiguchi
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  北海道札幌市　（札幌コンベンションセンター）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] An escape mutation selected by HIV-1-specific CTLs generates a novel CTL epitope2015
- Author(s)
  Tomohiro Akahoshi, Madoka Koyanagi, Hayato Murakoshi, Nozomi Kuse, and Masafumi Takiguchi
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  北海道札幌市　（札幌コンベンションセンター）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] 7.Identification of HLA-associated polymorphisms in a cohort of HIV-1 subtype A/E infection2015
- Author(s)
  Tran Van Giang, Takayuki Chikata, Yoshiko Tamura, Tomohiro Akahoshi, Hayato Murakoshi, Nozomi Kuse, Shinichi Oka, Keiko Sakai, Nguyen Van Kinh, Masafumi Takiguchi
- Organizer
  IAS 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] ベトナム人HIV-１感染者に見られるHIV-1感染制御に関与したHIV-1特異的細胞傷害性T細胞2015
- Author(s)
  田村美子, 村越勇人, 丸山理恵, Dung Hoai Nguyen, Giang Van Tran, 赤星智寛, 久世望, 近田貴敬, 阪井恵子, 小柳円, 酒井幸子, 岡慎一, Kinh Van Nguyen, 滝口雅文
- Organizer
  第29回日本エイズ学会学術集会・総会
- Place of Presentation
  東京都文京区（東京ドームホテル）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] The impact of one amino-acid substitution outside the binding groove between HLA-C*03 subtypes in binding of HIV-1 peptide to the HLA molecules2015
- Author(s)
  Takayuki Chikata, Hayato Murakoshi, Madoka Koyanagi, Tomohiro Akahoshi, and Masafumi Takiguchi
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  北海道札幌市　（札幌コンベンションセンター）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] ベトナム人慢性HIV-1感染者におけるHIV-1特異的細胞傷害性T細胞の網羅的解析2015
- Author(s)
  村越勇人, 田村美子, 丸山理恵, Dung Hoai Nguyen, Giang Van Tran, 赤星智寛, 久世　望, 阪井恵子, 小柳円, 酒井幸子, 岡慎一, Kinh Van Nguyen, 滝口雅文
- Organizer
  第29回日本エイズ学会学術集会・総会
- Place of Presentation
  東京都文京区（東京ドームホテル）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] ベトナム人HIV-1 subtype A/E 感染者コホートにおけるHLA-associated polymorphism の同定2015
- Author(s)
  近田貴敬, Giang Van Tran, Jonathan Carlson, 村越勇人, Dung Hoai Nguyen, 田村美子, 赤星智寛, 久世望, 阪井恵子, 小柳円, 酒井幸子, Kyle Cobarrubias, 岡慎一, Zabrina Brumme, Kinh Van Nguyen, 滝口雅文
- Organizer
  第29回日本エイズ学会学術集会・総会
- Place of Presentation
  東京都文京区（東京ドームホテル）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] 1.Control of HIV-1 by cytotoxic T cells specific for multiple conserved epitopes2015
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Takuya Naruto, Rie Maruyama, Yoshiko Tamura, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  IAS 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19588
[Presentation] Cross-clade CD8+ T cell responses in chronically HIV-1 clade A/E-infected individuals2013
- Author(s)
  Koji Watanabe, Hayato Murakoshi, Madoka Koyanagi, Takayuki Chikata and Masafumi Takiguchi
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Cross-clade CD8+ T cell responses in chronically HIV-1 clade A/E-infected individuals2013
- Author(s)
  Hayato Murakoshi, Koji Watanabe, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi
- Organizer
  AIDS Vaccine 2013
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Reversion of a CTL escape mutation by escape mutant-specific CTLs2013
- Author(s)
  Tomohiro Akahoshi, Hayato Murakoshi and Masafumi Takiguchi
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] 日本人HIV-1感染者で見られるHIV-1増殖抑制能に関与する細胞傷害性T細胞2013
- Author(s)
  村越勇人
- Organizer
  第27回日本エイズ学会学術集会・総会
- Place of Presentation
  熊本市国際交流会館、市民会館崇城大学ホール/熊本市民会館（熊本県熊本市）
- Invited
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Synergistic CTL responses effect on viraemia control of HIV-1 infection in Japanese individuals carrying HLA-B*35:01 allele associated with rapid disease progression2013
- Author(s)
  Madoka Koyanagi, Hayato Murakoshi and Masafumi Takiguchi
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] HIV-1 polymorphisms associated with 4-digit HLA alleles in Japanese individuals chronically infected with the clade B virus2013
- Author(s)
  Takayuki Chikata, Jonathan M Carlson, Yoshiko Tamura, Mohamed Ali Borghan, Takuya Naruto, Masao Hashimoto, Hayato Murakoshi, Simon Mallal, Mina John, Hiroyuki Gatanaga, Shinichi Oka, Zabrina L. Brumme and Masafumi Takiguchi
- Organizer
  AIDS Vaccine 2013
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] 日本人と白人におけるHIV-1サブタイプBのHLA-Associated Polymorphismの比較解析2013
- Author(s)
  近田貴敬, Jonathan M Carlson, 田村美子, Mohamed Ali Borghan, 成戸卓也, 端本昌夫, 村越勇人, Simon Mallal, Mina John, 潟永博之, 岡慎一, Zabrina L Brumme, 滝口雅文
- Organizer
  第27回日本エイズ学会学術集会・総会
- Place of Presentation
  熊本市国際交流会館、市民会館崇城大学ホール/熊本市民会館（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Control of HIV-1 by HIV-1-specific CD8+ T cells in chronically HIV-1-infected Japanese individuals2013
- Author(s)
  Hayato Murakoshi, Madoka Koyanagi and Masafumi Takiguchi
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Establishment of a cohort of treatment-naive patients chronically infected with HIV-1 in Hanoi2013
- Author(s)
  Tran Van Giang, Tomohiro Akahoshi, Hayato Murakoshi, Nozomi Kuse, Madoka Koyanagi, Takayuki Chikata, Yoshiko Tamura, Nguyen T. Hoai Dung, Nguyen Vu Trung, Junko Tanuma, Keiko Sakai, Shinichi Oka, Nguyen Van Kinh and Masafumi Takiguchi
- Organizer
  第27回日本エイズ学会学術集会・総会
- Place of Presentation
  熊本市国際交流会館、市民会館崇城大学ホール/熊本市民会館（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Effect of drug resistant mutations on HIV-1-specific CTL recognition2013
- Author(s)
  Mohammad Arif Rahman, Nozomi Kuse, Hayato Murakoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi
- Organizer
  第27回日本エイズ学会学術集会・総会
- Place of Presentation
  熊本市国際交流会館、市民会館崇城大学ホール/熊本市民会館（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Synergistic effect of multiple CTLs on control of HIV-1 in Japanese individuals carrying HLA-B*35:01 allele associated with rapid disease progression2013
- Author(s)
  Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka and Masafumi Takiguchi
- Organizer
  AIDS Vaccine 2013
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-25870550
[Presentation] Effective control of HIV-1 by cytotoxic T cells specific for multiple conserved epitopes
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, and Masafumi Takiguchi
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25870550

1. GATANAGA Hiroyuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. CHIKATA Takayuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
3. TAMURA Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. AKAHOSHI Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. KUSE Nozomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 小柳円

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 滝口雅文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 岡慎一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MURAKOSHI HAYATO 村越 勇人

Research Projects

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Co-Researchers

Mechanism for control of HIV-1 by cytotoxic T lymphocytePrincipal Investigator

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Study on HIV-1-specific cytotoxic T lymphocytes responsible for AIDS progression in HIV-1-infected individualsPrincipal Investigator

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Study on HIV-1-specific cytotoxic T cells effectively controlling HIV-1Principal Investigator

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[Journal Article] Contribution of Proteasome-Catalyzed Peptide cis-splicing to Viral Targeting by CD8 + T Cells in HIV-1 Infection2019

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[Journal Article] Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication2019

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[Journal Article] Effective suppression of HIV-1 replication by CTLs specific for Pol epitopes in conserved mosaic vaccine immunogens2019

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[Journal Article] Identification of immunodominant HIV-1 epitopes presented by HLA-C*12:02, a protective allele, using an immunopeptidomics approach2019

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[Journal Article] CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication2018

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[Journal Article] Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control2018

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[Journal Article] Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype2017

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[Journal Article] Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017

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[Journal Article] Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines2017

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[Journal Article] HLA Class I-Mediated HIV-1 Control in Vietnamese Infected with HIV-1 Subtype A/E2017

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[Journal Article] Novel conserved-region T-cell mosaic vaccine with high global HIV-1 coverage is recognized by protective responses in untreated infection2016

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[Journal Article] A strong association of HLA-associated Pol and Gag mutations with clinical parameters2016

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MURAKOSHI HAYATO 村越勇人

[Journal Article] Impact of a single HLA-A24:02-associated escape mutation on the detrimental effect of HLA-B35:01 in HIV-1 control2018

[Journal Article] Control of HIV-1 by an HLA-B52:01-C12:02 Protective Haplotype2017

[Journal Article] Accumulation of Pol Mutations Selected by HLA-B52:01-C12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017