Kondo Hiroko 近藤寛子

… Alternative Names

近藤寛子コンドウヒロコ

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Researcher Number	60700028
Other IDs
Affiliation (Current)	2025: 北見工業大学, 工学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 北見工業大学, 工学部, 准教授 2019 – 2023: 北見工業大学, 工学部, 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (II) / Basic Section 43040:Biophysics-related Except Principal Investigator Basic Section 43040:Biophysics-related / Basic Section 34030:Green sustainable chemistry and environmental chemistry-related
Keywords	Principal Investigator 分子シミュレーション / 機械学習 / 構造機能相関 / データベース / 分子力場 / ヘムタンパク質 Except Principal Investigator 量子化学計算 / 分子動力学シミュレーション / 蛋白質 / 分子力場 … More / 二次構造 / 水素結合 / 水系合成化学 / 反応工学 / 汚染物質除去 / ゼータ電位 / 分子動力学 / フローテーション / 水系反応 / 薬物分離 / 精製技術 / 色素 / グリーン化学 / 低環境負荷プロセス / 反応分離工学 / 染色排水 / 医療排水 / 迅速精製 / 排水処理 / 塩基性薬物 / 塩基性色素 / 気泡 / 水溶液 / 低環境負荷 / 疎水相互作用 / 分離 / 薬物 / 気液界面 / 密度汎関数法 Less

シトクロムP450における触媒反応の多様性の原理の解明と機能予測モデルの構築Principal Investigator
- Principal Investigator
  
  近藤寛子
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Kitami Institute of Technology
タンパク質により生み出されるヘムの多機能性の起源の解明Principal Investigator
- Principal Investigator
  
  近藤寛子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kitami Institute of Technology
Computational study on the secondary structure dependence of the interaction in protein tertiary structure formation and the development of a new force field
- Principal Investigator
  
  鷹野優
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Hiroshima City University
Elucidation of dependence of secondary structure on the formation of protein structure and development of new forcefield incorporating effects of secondary structure
- Principal Investigator
  
  Takano Yu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Hiroshima City University
Creation of air-water interface-modified region for drug separation and design of sustainable water-based reaction and separation engineering
- Principal Investigator
  
  Saitoh Tohru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 34030:Green sustainable chemistry and environmental chemistry-related
- Research Institution
  Kitami Institute of Technology

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Negative fragmentation approach for investigating the depolarization effect of neighboring residues on hydrogen bonds in π-helix2023
- Author(s)
  Kondo Hiroko X.、Nakamura Haruki、Takano Yu
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 815 Pages: 140361-140361
- DOI
  10.1016/j.cplett.2023.140361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589
[Journal Article] Prediction of Protein Function from Tertiary Structure of the Active Site in Heme Proteins by Convolutional Neural Network2023
- Author(s)
  Kondo Hiroko X.、Iizuka Hiroyuki、Masumoto Gen、Kabaya Yuichi、Kanematsu Yusuke、Takano Yu
- Journal Title
  
  Biomolecules
  
  Volume: 13 Issue: 1 Pages: 137-137
- DOI
  10.3390/biom13010137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PROJECT-21K14741, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589, KAKENHI-PUBLICLY-22H04813
[Journal Article] Computational Exploration of Minimum Energy Reaction Pathway of N2O Formation from Intermediate I of P450nor Using an Active Center Model2023
- Author(s)
  Kanematsu Yusuke、Kondo Hiroko X.、Takano Yu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 24 Pages: 17172-17172
- DOI
  10.3390/ijms242417172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PROJECT-23K05707, KAKENHI-PUBLICLY-22H04813, KAKENHI-PLANNED-20H05883
[Journal Article] Random Forest Classifier of Heme Proteins Using Porphyrin Distortions and Axial Ligands of Heme2023
- Author(s)
  Fujikawa Hinako、Kondo Hiroko X.、Kanematsu Yusuke、Takano Yu
- Journal Title
  
  Chemistry Letters
  
  Volume: 52 Issue: 6 Pages: 503-507
- DOI
  10.1246/cl.230150
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PROJECT-23K05707, KAKENHI-PROJECT-21K14741, KAKENHI-PUBLICLY-22H04813, KAKENHI-PLANNED-20H05883
[Journal Article] Global Analysis of Heme Proteins Elucidates the Correlation between Heme Distortion and the Heme-Binding Pocket2022
- Author(s)
  Kondo Hiroko X.、Fujii Masanori、Tanioka Takuma、Kanematsu Yusuke、Yoshida Takashi、Takano Yu
- Journal Title
  
  Journal of Chemical Information and Modeling
  
  Volume: 62 Issue: 4 Pages: 775-784
- DOI
  10.1021/acs.jcim.1c01315
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589, KAKENHI-PROJECT-21K14741
[Journal Article] Analysis of Fluctuation in the Heme-Binding Pocket and Heme Distortion in Hemoglobin and Myoglobin2022
- Author(s)
  Kondo Hiroko X.、Takano Yu
- Journal Title
  
  Life
  
  Volume: 12 Issue: 2 Pages: 210-210
- DOI
  10.3390/life12020210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589
[Journal Article] Elucidation of the Correlation between Heme Distortion and Tertiary Structure of the Heme-Binding Pocket Using a Convolutional Neural Network2022
- Author(s)
  Kondo Hiroko X.、Iizuka Hiroyuki、Masumoto Gen、Kabaya Yuichi、Kanematsu Yusuke、Takano Yu
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 9 Pages: 1172-1172
- DOI
  10.3390/biom12091172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589, KAKENHI-PUBLICLY-22H04813, KAKENHI-PROJECT-21K14741
[Journal Article] Effects of Active-Center Reduction of Plant-Type Ferredoxin on Its Structure and Dynamics: Computational Analysis Using Molecular Dynamics Simulations2022
- Author(s)
  Nakayoshi Tomoki、Ohnishi Yusuke、Tanaka Hideaki、Kurisu Genji、Kondo Hiroko X.、Takano Yu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 24 Pages: 15913-15913
- DOI
  10.3390/ijms232415913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PLANNED-20H05879, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-21H02417
[Journal Article] Conformational Preference of Flavonols and Its Effect on the Chemical Properties Involved in Radical Scavenging Activity2022
- Author(s)
  Kondo Hiroko X.、Takano Yu
- Journal Title
  
  Chemistry
  
  Volume: 4 Issue: 4 Pages: 1123-1135
- DOI
  10.3390/chemistry4040076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589
[Journal Article] Quantum chemical studies on hydrogen bonds in helical secondary structures2022
- Author(s)
  Takano Yu、Kondo Hiroko X.、Nakamura Haruki
- Journal Title
  
  Biophysical Reviews
  
  Volume: 14 Issue: 6 Pages: 1369-1378
- DOI
  10.1007/s12551-022-01034-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589
[Journal Article] Structure of Heme-binding Pocket in Heme Protein is Generally Rigid and can be Predicted by AlphaFold22022
- Author(s)
  Kondo Hiroko X.、Kanematsu Yusuke、Takano Yu
- Journal Title
  
  Chemistry Letters
  
  Volume: 51 Issue: 7 Pages: 704-708
- DOI
  10.1246/cl.220172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589, KAKENHI-PUBLICLY-22H04813
[Journal Article] Depolarizing Effects in Hydrogen Bond Energy in 310-Helices Revealed by Quantum Chemical Analysis2022
- Author(s)
  Kondo Hiroko X.、Nakamura Haruki、Takano Yu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 16 Pages: 9032-9032
- DOI
  10.3390/ijms23169032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06164, KAKENHI-PLANNED-20H05883, KAKENHI-PROJECT-19K06589
[Journal Article] PyDISH: database and analysis tools for heme porphyrin distortion in heme proteins2020
- Author(s)
  Kondo Hiroko X、Kanematsu Yusuke、Masumoto Gen、Takano Yu
- Journal Title
  
  Database
  
  Volume: 2020
- DOI
  10.1093/database/baaa066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06589, KAKENHI-PROJECT-19H02752
[Journal Article] Effects of a remote mutation from the contact paratope on the structure of CDR-H3 in the anti-HIV neutralizing antibody PG162019
- Author(s)
  Kondo Hiroko X.、Kiribayashi Ryo、Kuroda Daisuke、Kohda Jiro、Kugimiya Akimitsu、Nakano Yasuhisa、Tsumoto Kouhei、Takano Yu
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 19840-19840
- DOI
  10.1038/s41598-019-56154-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06589, KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202, KAKENHI-PROJECT-17H06109
[Journal Article] Hydrogen bond donors and acceptors are generally depolarized in ホア窶辛elices as revealed by a molecular tailoring approach2019
- Author(s)
  *H. X. Kondo, A. Kusaka, C. K. Kitakawa, J. Onari, S. Yamanaka, H. Nakamura, *Y. Takano
- Journal Title
  
  Journal of Computational Chemistry
  
  Volume: 40 Issue: 23 Pages: 2043-2052
- DOI
  10.1002/jcc.25859
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07325, KAKENHI-PROJECT-19K06589, KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-19H02752
[Presentation] 機械学習手法を用いたヘムタンパク質における構造機能相関の解析2023
- Author(s)
  近藤寛子
- Organizer
  レア・イベントの計算科学第6回ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-23K05707
[Presentation] Analysis of structure-function correlation in the active sites of heme proteins2023
- Author(s)
  近藤寛子, 飯塚博幸, 舛本現, 兼松佑典, 鷹野優
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-23K05707
[Presentation] ヒスチジン二残基を軸配位子とするヘムbの分子力場パラメータの決定と検証2023
- Author(s)
  仲吉朝希・近藤寛子・酒井友紀菜・兼松佑典・新井博文・鷹野優
- Organizer
  第51回構造活性相関シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06164
[Presentation] Depolarizing effects in hydrogen bond energy in 310-helices revealed by quantum chemical analysis2022
- Author(s)
  Yu Takano, Hiroko X. Kondo, Haruki Nakamura
- Organizer
  International Congress on Pure & Applied Chemistry Kota Kinabalu
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Depolarizing effects in hydrogen bond energy in 310-helices revealed by quantum chemical analysis2022
- Author(s)
  Yu Takano, Hiroko X. Kondo, Haruki Nakamura
- Organizer
  International Congress on Pure & Applied Chemistry Yangon (ICPAC Kota Kinabalu) 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06164
[Presentation] ヘム蛋白質における構造機能相関の解明に向けたヘム結合部位のタンパク質環境とヘムの歪みの相関解析2021
- Author(s)
  近藤寛子，飯塚博幸，舛本現，兼松佑典，鷹野優
- Organizer
  日本コンピュータ化学会2021年秋季年会
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Computational study of the structural function relationship of heme proteins2021
- Author(s)
  Yu Takano, Hiroko X. Kondo, Yusuke Kanematsu
- Organizer
  第57回日本生物物理学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] ヘムタンパク質における構造機能相関の解明に向けたタンパク質ポケットとヘムの歪みの相関解析2021
- Author(s)
  近藤寛子，飯塚博幸，舛本現，兼松佑典，鷹野優
- Organizer
  第21回日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] PyDISH: Database and analysis tools for heme porphyrin distortion in heme proteins2020
- Author(s)
  鷹野優・近藤寛子・兼松佑典・舛本現
- Organizer
  第58回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Quantum chemical analysis of the hydrogen bond interactions in secondary structures of proteins with Negative Fragmentation Approach2020
- Author(s)
  Yu Takano, Hiroko X. Kondo, Haruki Nakamura
- Organizer
  The 60th Sanibel Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] ヘムタンパク質におけるヘム周囲のタンパク質環境とヘムの歪みの網羅解析2020
- Author(s)
  近藤寛子・藤井理則・谷岡卓磨・兼松佑典・吉田孝・鷹野優
- Organizer
  錯体化学会第70回討論会
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] ヘムの構造歪みデータベースおよび解析ツールPyDISHの開発2020
- Author(s)
  鷹野優・近藤寛子・兼松佑典・舛本現
- Organizer
  日本コンピュータ化学会2020秋季年会
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Analysis of an effect of mutations on the structure of CDR-H3 in the anti-HIV neutralizing antibody PG162020
- Author(s)
  近藤寛子・桐林遼・黒田大祐・津本浩平・鷹野優
- Organizer
  第58回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Hydrogen bond donors and acceptors are generally depolarized in α-helices as revealed by a molecular tailoring approach2019
- Author(s)
  近藤寛子・草鹿あゆみ・中村春木・鷹野優
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Negative Fragmentation Approachを用いたタンパク質の二次構造における相互作用エネルギーの解析2019
- Author(s)
  近藤寛子，草鹿あゆみ，中村春木，鷹野優
- Organizer
  日本コンピュータ化学会2019秋季年会
- Data Source
  KAKENHI-PROJECT-19H02752
[Presentation] Hydrogen bond donors and acceptors are generally depolarized in α-helices as revealed by a negative fragmentation approach2019
- Author(s)
  Yu Takano, Hiroko X. Kondo, Ayumi Kusaka, Shusuke Yamanaka, Haruki Nakamura
- Organizer
  International Congress on Pure & Applied Chemistry Yangon 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Hydrogen bond donors and acceptors are generally depolarized in α-helices as revealed by a molecular tailoring approach2019
- Author(s)
  Hiroko X. Kondo, Ayumi Kusaka, Haruki Nakamura, Yu Takano
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19H02752
[Presentation] ヘムの構造歪みに着目した統計解析・電子状態計算による構造機能相関の解明とデータベースの構築2019
- Author(s)
  近藤寛子，兼松佑典，藤井理則，石井学，舛本現，今田康博，吉田孝，鷹野優
- Organizer
  第46回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-19H02752
[Presentation] Negative Fragmentation Approachを用いたタンパク質の二次構造における相互作用エネルギーの解析2019
- Author(s)
  近藤寛子・草鹿あゆみ・中村春木・鷹野優
- Organizer
  日本コンピュータ化学会2019秋季年会
- Data Source
  KAKENHI-PROJECT-19K06589
[Presentation] Hydrogen bond donors and acceptors are generally depolarized in α-helices as revealed by a negative fragmentation approach2019
- Author(s)
  鷹野優・近藤寛子・草鹿あゆみ・山中秀介・中村春木
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K06589

1. Takano Yu (30403017)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
2. Saitoh Tohru (40186945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 林英男 (10385536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 安田啓司 (80293645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAMURA Haruki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kondo Hiroko 近藤 寛子

近藤 寛子 コンドウ ヒロコ

Research Projects

Research Products

Co-Researchers

シトクロムP450における触媒反応の多様性の原理の解明と機能予測モデルの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

タンパク質により生み出されるヘムの多機能性の起源の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Computational study on the secondary structure dependence of the interaction in protein tertiary structure formation and the development of a new force field

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of dependence of secondary structure on the formation of protein structure and development of new forcefield incorporating effects of secondary structure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Creation of air-water interface-modified region for drug separation and design of sustainable water-based reaction and separation engineering

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Negative fragmentation approach for investigating the depolarization effect of neighboring residues on hydrogen bonds in π-helix2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of Protein Function from Tertiary Structure of the Active Site in Heme Proteins by Convolutional Neural Network2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational Exploration of Minimum Energy Reaction Pathway of N2O Formation from Intermediate I of P450nor Using an Active Center Model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Random Forest Classifier of Heme Proteins Using Porphyrin Distortions and Axial Ligands of Heme2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global Analysis of Heme Proteins Elucidates the Correlation between Heme Distortion and the Heme-Binding Pocket2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of Fluctuation in the Heme-Binding Pocket and Heme Distortion in Hemoglobin and Myoglobin2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidation of the Correlation between Heme Distortion and Tertiary Structure of the Heme-Binding Pocket Using a Convolutional Neural Network2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Active-Center Reduction of Plant-Type Ferredoxin on Its Structure and Dynamics: Computational Analysis Using Molecular Dynamics Simulations2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conformational Preference of Flavonols and Its Effect on the Chemical Properties Involved in Radical Scavenging Activity2022

Author(s)

Journal Title

DOI

Data Source

Kondo Hiroko 近藤寛子

近藤寛子コンドウヒロコ

[Presentation] ヘム蛋白質における構造機能相関の解明に向けたヘム結合部位のタンパク質環境とヘムの歪みの相関解析2021