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Homma Kengo  本間 謙吾

ORCIDConnect your ORCID iD *help
Researcher Number 60708171
Other IDs
Affiliation (based on the past Project Information) *help 2019: 東京医科歯科大学, 難治疾患研究所, 講師
2017: 東京大学, 大学院薬学系研究科(薬学部), 特任研究員
2016: 東京大学, 大学院薬学系研究科(薬学部), 特任助教
2015: 東京大学, 薬学研究科(研究院), 助教
2015: 東京大学, 薬学研究科(研究院), 特任助教
2014: 東京大学, 薬学研究科(研究院), 研究員
Review Section/Research Field
Principal Investigator
Functional biochemistry / Complex systems
Keywords
Principal Investigator
SOD1 / ALS / 神経細胞 / 恒常性維持 / 数理シグナル / JNK / 運動機能障害 / MKK7 / 構造変化 / 亜鉛トランスポーター … More / 亜鉛 / Derlin-1 / PPI阻害剤 / PPI阻害 / 低分子化合物 Less
  • Research Projects

    (3 results)
  • Research Products

    (4 results)
  •  神経細胞の恒常性を維持するMKK7-JNK経路の解析Principal Investigator

    • Principal Investigator
      本間 謙吾
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo Medical and Dental University
  •  Revealing the molecular mechanism of regulating SOD1 proteostasis by zinc-related genes for understanding ALS pathogenesisPrincipal Investigator

    • Principal Investigator
      Homma Kengo
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  Identification of chemical compounds inhibiting SOD1-Derlin-1 interaction for ALS treatmentPrincipal Investigator

    • Principal Investigator
      Homma Kengo
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo

All 2016 Other

All Presentation

  • [Presentation] SOD1-Derlin-1結合を標的としたALS治療薬の基盤開発2016

    • Author(s)
      本間謙吾
    • Organizer
      第68回日本細胞生物学会
    • Place of Presentation
      京都、京都テルサ
    • Year and Date
      2016-06-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-26650028
  • [Presentation] ゲノムワイドsiRNAスクリーニングによるSOD1の構造制御機構の解明2016

    • Author(s)
      本間謙吾
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K18513
  • [Presentation] SOD1 as a molecular switch for initiating the homeostatic ER stress response under conditions of zinc deficiency

    • Author(s)
      Kengo Homma and Hidenori Ichijo
    • Organizer
      日本生化学会大会
    • Place of Presentation
      日本、京都
    • Year and Date
      2014-10-14 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26650028
  • [Presentation] SOD1 AS A MOLECULAR SWITCH FOR INITIATING THE HOMEOSTATIC ER STRESS RESPONSE UNDER ZINC DEFICIENCY

    • Author(s)
      Kengo Homma and Hidenori Ichijo
    • Organizer
      The 4th International Society for Zinc Biology Meeting
    • Place of Presentation
      Asiloma, Pacific Grove, CA, USA
    • Year and Date
      2014-09-14 – 2014-09-19
    • Data Source
      KAKENHI-PROJECT-26650028

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