Hara Keijiro 原慶次郎

… Alternative Names

原慶次郎ハラケイジロウ

HARA Keijirou 原慶次郎

Less

Researcher Number	60710340
Other IDs	https://orcid.org/0000-0002-0983-5229
Affiliation (Current)	2025: 徳島大学, 病院, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 徳島大学, 病院, 特任講師 2015: 徳島大学, 大学病院, 助教 2015: 徳島大学, 病院, 助教 2013: 徳島大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related Except Principal Investigator Neurosurgery
Keywords	Principal Investigator 外傷性認知症 / タウ・リン酸化タウ沈着 / amyloid-β沈着 / 外傷性脳出血 / タウ蛋白 / アミロイドβ / 認知症関連蛋白 / 認知症 / 外傷性脳内出血 Except Principal Investigator Wntシグナル … More / Ad-REIC / 悪性脳腫瘍 / ｸﾞﾘｵﾌﾞﾗｽﾄｰﾏ / 遺伝子治療 / DKK3 / Wnt / グリオブラストーマ / 脳腫瘍 Less

脳内微量出血模倣モデルにおける認知症関連蛋白発現機序の解明と制御Principal Investigator
- Principal Investigator
  
  原慶次郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokushima
Anti-tumor effects and Regulation of Wnt signaling pathway of adenovirus-mediated DKK3 in glioblastoma
- Principal Investigator
  
  MIZOBUCHI Yoshifumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  The University of Tokushima

All 2023 2015 2013

All Journal Article Presentation

[Journal Article] Differences in amyloid-β and tau/p-tau deposition in blood-injected mouse brains using micro-syringe to mimic traumatic brain microhemorrhages2023
- Author(s)
  Kagusa Hiroshi、Yamaguchi Izumi、Shono Kenji、Mizobuchi Yoshifumi、Shikata Eiji、Matsuda Taku、Miyamoto Takeshi、Hara Keijiro、Kitazato Keiko T.、Uto Yoshihiro、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Chemical Neuroanatomy
  
  Volume: 130 Pages: 102258-102258
- DOI
  10.1016/j.jchemneu.2023.102258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16662, KAKENHI-PROJECT-22K09259
[Journal Article] Diagnosis of brain tumors using dynamic contrast-enhanced perfusion imaging with a short acquisition time2015
- Author(s)
  Abe T, Mizobuchi Y, Nakajima K, Otomi Y, Irahara S, Obama Y, Majigsuren M, Khashbat D, Kageji T, Nagahiro S, Harada M
- Journal Title
  
  Springerplus
  
  Volume: 4 Issue: 1 Pages: 88-88
- DOI
  10.1186/s40064-015-0861-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462264, KAKENHI-PROJECT-26861153
[Journal Article] Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma2015
- Author(s)
  Hara K, Kageji T, Mizobuchi Y, Kitazato KT, Okazaki T, Fujihara T, Nakajima K, Mure H, Kuwayama K, Hara T, Nagahiro S
- Journal Title
  
  Cancer Lett
  
  Volume: 356 Issue: 2 Pages: 496-505
- DOI
  10.1016/j.canlet.2014.09.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462264, KAKENHI-PROJECT-26861153
[Presentation] 外傷性脳内微小出血模倣モデルマウスにおける行動解析と認知症蛋白の蓄積・制御法の検討2023
- Author(s)
  鹿草宏、原慶次郎、藤原敏孝、中島公平、高木康志
- Organizer
  日本脳神経外科学会第82回学術総会
- Data Source
  KAKENHI-PROJECT-22K16662
[Presentation] 外傷性脳内微小出血模倣モデルマウスでの認知症関連蛋白の蓄積と制御法の検討2023
- Author(s)
  鹿草宏、原慶次郎、藤原敏孝、中島公平、高木康志
- Organizer
  第46回日本脳神経外傷学会
- Data Source
  KAKENHI-PROJECT-22K16662
[Presentation] Down-regulation of MDR1 by DKK3 attenuates chemoresistance to temozolomide, and potentiates its anti-tumor effects2015
- Author(s)
  T.Fujihara, T.Kageji, Y.Mizobuchi, R.Otsuka K.Kitazato, K.Hara, K.Shono, K.Nakajima H.Mure, K.Kuwayama, S.Nagahiro
- Organizer
  20th Annual Socientific Meeting and Education Day of the Society for Neuro-Oncology
- Place of Presentation
  Texas, USA
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] Sonodynamic 5-ALA plus ultrasound therapy augments anti-tumor effects in the oncogene knock-in glioma stemcells2015
- Author(s)
  K.Shono, T.Kageji, Y.Mizobuchi, T.Fujihara, K.Kitazato, K.Nakajima, H.Mure, K.Kuwayama, S.Nagahiro
- Organizer
  20th Annual Socientific Meeting and Education Day of the Society for Neuro-Oncology,
- Place of Presentation
  Texas,USA
- Year and Date
  2015-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] A combination of interferon-b and temozolomide augments anti-tumor effects through p73/YAP-mediated apoptosis by PML in glioblastoma2013
- Author(s)
  Y.Mizobuchi, T.Okazaki, T.Kageji, K.Kuwayama, K.T.Kitazato, H.Mure, K.Hara, R.Morigaki, K.Matsuzaki, K.Nakajima, T.Fujihara, S.Nagahiro
- Organizer
  SNO 2013
- Place of Presentation
  Marriott Marquis Hotel (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] Down-regulation of MDR by Ad-Dkk3 contributes to augment the chemotherapy by temozolomide2013
- Author(s)
  K.Nakajima, K.Hara, T.Kageji, Y.Mizobuchi, K.T.Kitazato, T.Fujihara, K.Kuwayama, R.Otsuka, D K.Kung, S.Nagahiro
- Organizer
  SNO 2013
- Place of Presentation
  Marriott Marquis Hotel (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-25462264
[Presentation] Dkk-3, one of Dickkopf (Dkk) family members, contributes to the anti-tumor effects in glioblastoma through regulation of both Wnt signal pathways2013
- Author(s)
  K.Hara, T.Kageji, Y.Mizobuchi, K.T.Kitazato, T.Okazaki, T.Fujihara, K.Nakajima, H.Mure, K.Kuwayama, T.Hara, S.Nagahiro
- Organizer
  SNO 2013
- Place of Presentation
  Marriott Marquis Hotel (San Francisco, USA)
- Data Source
  KAKENHI-PROJECT-25462264

1. MIZOBUCHI Yoshifumi (80547993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. MURE Hideo (00624355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. NAGAHIRO Shinji (60145315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. KAGEJI Teruyoshi (70294684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. KUWAYAMA Kazuyuki (50614236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. NAKAJIMA Kohei (40710554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

Hara Keijiro 原 慶次郎

原 慶次郎 ハラ ケイジロウ

HARA Keijirou 原 慶次郎

Research Projects

Research Products

Co-Researchers

脳内微量出血模倣モデルにおける認知症関連蛋白発現機序の解明と制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-tumor effects and Regulation of Wnt signaling pathway of adenovirus-mediated DKK3 in glioblastoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differences in amyloid-β and tau/p-tau deposition in blood-injected mouse brains using micro-syringe to mimic traumatic brain microhemorrhages2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnosis of brain tumors using dynamic contrast-enhanced perfusion imaging with a short acquisition time2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blocking of the interaction between Wnt proteins and their co-receptors contributes to the anti-tumor effects of adenovirus-mediated DKK3 in glioblastoma2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 外傷性脳内微小出血模倣モデルマウスにおける行動解析 と認知症蛋白の蓄積・制御法の検討2023

Author(s)

Organizer

Data Source

[Presentation] 外傷性脳内微小出血模倣モデルマウスでの認知症関連蛋白の蓄積と制御法の検討2023

Author(s)

Organizer

Data Source

[Presentation] Down-regulation of MDR1 by DKK3 attenuates chemoresistance to temozolomide, and potentiates its anti-tumor effects2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Sonodynamic 5-ALA plus ultrasound therapy augments anti-tumor effects in the oncogene knock-in glioma stemcells2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A combination of interferon-b and temozolomide augments anti-tumor effects through p73/YAP-mediated apoptosis by PML in glioblastoma2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Down-regulation of MDR by Ad-Dkk3 contributes to augment the chemotherapy by temozolomide2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Dkk-3, one of Dickkopf (Dkk) family members, contributes to the anti-tumor effects in glioblastoma through regulation of both Wnt signal pathways2013

Author(s)

Organizer

Place of Presentation

Data Source

Hara Keijiro 原慶次郎

原慶次郎ハラケイジロウ

HARA Keijirou 原慶次郎

[Presentation] 外傷性脳内微小出血模倣モデルマウスにおける行動解析と認知症蛋白の蓄積・制御法の検討2023