Yanagibashi Tsutomu 柳橋努

Researcher Number	60710887
Other IDs
Affiliation (Current)	2025: 富山県薬事総合研究開発センター, その他部局等, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 富山県薬事総合研究開発センター, その他部局等, 主任研究員 2018 – 2023: 富山県薬事総合研究開発センター, その他部局等, 主任研究員 2017: 富山県薬事研究所, その他部局等, 主任研究員 2015 – 2017: 富山県薬事研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Food science Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords	Principal Investigator IL-5 / 腸内細菌 / IgA / IL-33 / ビタミンA Except Principal Investigator 前向きコホート研究 / 非IgE依存的アレルギー性鼻炎 / 小児コホート研究 / 神経 / ILC2 … More / 花粉症 / IL-5 / 唾液サイトカイン / コホート研究 / 自然型アレルギー / スギ花粉症 / 唾液中サイトカイン / 唾液細菌叢 / 唾液 / IL-5産生ILC2 / アレルギー性鼻炎 Less

腸内細菌によるILC2のIL-5産生抑制を基軸とした好酸球制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  柳橋努
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Toyama Prefectural Institute for Pharmaceutical Research
Analysis of homeostatic mechanisms of intestinal bacteria with a focus on IL-5-producing cellsPrincipal Investigator
- Principal Investigator
  
  Tsutomu Yanagibashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Toyama Prefectural Institute for Pharmaceutical Research
Mechanisms of non-IgE-dependent allergic rhinitis pathogenesis triggered by IL-5.
- Principal Investigator
  
  Yamazaki-Nagai Terumi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kanazawa University
  University of Toyama
Elucidation of colon homeostasis focusing on the crosstalk between gut microbiota and IL-5-producing cellsPrincipal Investigator
- Principal Investigator
  
  Yanagibashi Tsutomu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Toyama Prefectural Institute for Pharmaceutical Research
Stadies on IgA induction in the large intestine by vitamin APrincipal Investigator
- Principal Investigator
  
  Yanagibashi Tsutomu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Toyama Prefectural Institute. for Pharmaceutical Research.

All 2023 2022 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Impact of Vancomycin Treatment and Gut Microbiota on Bile Acid Metabolism and the Development of Non-Alcoholic Steatohepatitis in Mice2023
- Author(s)
  Kasai Kaichi、Igarashi Naoya、Tada Yuki、Kani Koudai、Takano Shun、Yanagibashi Tsutomu、Usui-Kawanishi Fumitake、Fujisaka Shiho、Watanabe Shiro、Ichimura-Shimizu Mayuko、Takatsu Kiyoshi、Tobe Kazuyuki、Tsuneyama Koichi、Furusawa Yukihiro、Nagai Yoshinori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 4050-4050
- DOI
  10.3390/ijms24044050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05466, KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-20K19676
[Journal Article] Roles of Macrophages in Advanced Liver Fibrosis, Identified Using a Newly Established Mouse Model of Diet-Induced Non-Alcoholic Steatohepatitis2022
- Author(s)
  Tada Yuki、Kasai Kaichi、Makiuchi Nana、Igarashi Naoya、Kani Koudai、Takano Shun、Honda Hiroe、Yanagibashi Tsutomu、Watanabe Yasuharu、Usui-Kawanishi Fumitake、Furusawa Yukihiro、Ichimura-Shimizu Mayuko、Tabuchi Yoshiaki、Takatsu Kiyoshi、Tsuneyama Koichi、Nagai Yoshinori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 21 Pages: 13251-13251
- DOI
  10.3390/ijms232113251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05466, KAKENHI-PROJECT-22K06627, KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-22K08685
[Journal Article] Betulin Attenuates TGF-β1- and PGE<sub>2</sub>-Mediated Inhibition of NK Cell Activity to Suppress Tumor Progression and Metastasis in Mice2022
- Author(s)
  Ogasawara Masaru、Yamasaki-Yashiki Shino、Hamada Masahiro、Yamaguchi-Miyamoto Tomomi、Kawasuji Toru、Honda Hiroe、Yanagibashi Tsutomu、Ikutani Masashi、Watanabe Yasuharu、Fujimoto Ryota、Matsunaga Takayuki、Nakajima Noriyuki、Nagai Yoshinori、Takatsu Kiyoshi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 3 Pages: 339-353
- DOI
  10.1248/bpb.b21-00921
- NAID
  130008165815
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07076, KAKENHI-PROJECT-19K09019, KAKENHI-PROJECT-21K05466
[Journal Article] Elimination of eosinophils using anti-IL-5 receptor alpha antibodies effectively suppresses IL-33-mediated pulmonary arterial hypertrophy2018
- Author(s)
  Ikutani Masashi、Ogawa Shinya、Yanagibashi Tsutomu、Nagai Terumi、Okada Kazuki、Furuichi Yoko、Takatsu Kiyoshi
- Journal Title
  
  Immunobiology
  
  Volume: 223 Issue: 6-7 Pages: 486-492
- DOI
  10.1016/j.imbio.2017.12.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15739, KAKENHI-PROJECT-15K18706
[Journal Article] Allergic diseases: From bench to clinic - Contribution of the discovery of interleukin-52017
- Author(s)
  Yanagibashi T、Satoh M、Nagai Y、Koike M、Takatsu K
- Journal Title
  
  Cytokine
  
  Volume: 98 Pages: 59-70
- DOI
  10.1016/j.cyto.2016.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-15K18706
[Presentation] Vitamin A-dependent IL-33 production maintains IL-5-producing ILC2s in the large intestine2019
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05499
[Presentation] The role of IL-5-producing group 2 innate lymphoid cells in the large intestin2018
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Yukihiko Aikawa, Kiyoshi Takatsu
- Organizer
  The 5th Toyama-Basel Joint Symposium on Pharmaceutical Research and Drug Development
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05499
[Presentation] IL-5-producing ILC2s in the large intestine contribute to T cell-independent IgA production through theregulation of eosinophil homeostasis.2017
- Author(s)
  Tsutomu Yanagibashi、 Masashi Ikutani、Yoshinori　Nagai、Kiyoshi Takatsu
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K18706
[Presentation] IL-5-producing ILC2s regulate T cell-independent IgA production in the large intestine2016
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  4th Toyama-Basel Joint Symposium
- Place of Presentation
  University of Basel（スイス）
- Year and Date
  2016-08-25
- Data Source
  KAKENHI-PROJECT-15K18706
[Presentation] Role of IL-5-producing ILC2s in the T cell independent-IgA production in the intestine2015
- Author(s)
  Yanagibashi Tsutomu, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第44回　日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道、札幌市）
- Year and Date
  2015-11-17
- Data Source
  KAKENHI-PROJECT-15K18706

1. Yamazaki-Nagai Terumi (20558134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 土田暁子 (00867674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. IKUTANI Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. Takatsu Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. NAGAI Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yanagibashi Tsutomu 柳橋 努

Research Projects

Research Products

Co-Researchers

腸内細菌によるILC2のIL-5産生抑制を基軸とした好酸球制御メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of homeostatic mechanisms of intestinal bacteria with a focus on IL-5-producing cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of non-IgE-dependent allergic rhinitis pathogenesis triggered by IL-5.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of colon homeostasis focusing on the crosstalk between gut microbiota and IL-5-producing cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Stadies on IgA induction in the large intestine by vitamin APrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of Vancomycin Treatment and Gut Microbiota on Bile Acid Metabolism and the Development of Non-Alcoholic Steatohepatitis in Mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles of Macrophages in Advanced Liver Fibrosis, Identified Using a Newly Established Mouse Model of Diet-Induced Non-Alcoholic Steatohepatitis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Betulin Attenuates TGF-β1- and PGE<sub>2</sub>-Mediated Inhibition of NK Cell Activity to Suppress Tumor Progression and Metastasis in Mice2022

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Elimination of eosinophils using anti-IL-5 receptor alpha antibodies effectively suppresses IL-33-mediated pulmonary arterial hypertrophy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Allergic diseases: From bench to clinic - Contribution of the discovery of interleukin-52017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Vitamin A-dependent IL-33 production maintains IL-5-producing ILC2s in the large intestine2019

Author(s)

Organizer

Data Source

[Presentation] The role of IL-5-producing group 2 innate lymphoid cells in the large intestin2018

Author(s)

Organizer

Data Source

[Presentation] IL-5-producing ILC2s in the large intestine contribute to T cell-independent IgA production through theregulation of eosinophil homeostasis.2017

Author(s)

Organizer

Data Source

[Presentation] IL-5-producing ILC2s regulate T cell-independent IgA production in the large intestine2016

Author(s)

Organizer

Place of Presentation

Year and Date

Yanagibashi Tsutomu 柳橋努