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Murakami Akari  村上 朱里

ORCIDConnect your ORCID iD *help
Researcher Number 60722593
Affiliation (Current) 2025: 愛媛大学, 医学部附属病院, 助教(病院教員)
Affiliation (based on the past Project Information) *help 2019 – 2021: 愛媛大学, 医学部附属病院, 助教(病院教員)
2018: 愛媛大学, 医学部附属病院, 助教
2017 – 2018: 愛媛大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / General surgery
Keywords
Principal Investigator
HER2陽性乳癌 / CUL3 / 細胞膜形態変化 / タンパク質間相互作用 / アルファスクリーン / Rac1 / 細胞膜 / ユビキチンリガーゼ / 幹細胞 / 細胞膜形態 … More / 乳癌細胞 / 乳癌細胞特性解析 / 細胞特性 / 乳癌 Less
  • Research Projects

    (2 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (9 People)
  •  Development of Novel Therapeutic Agents Targeting Regulatory Mechanisms of Cell Membrane Morphology for HER2-positive breast cancerPrincipal Investigator

    • Principal Investigator
      Murakami Akari
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Ehime University
  •  Functional analysis of ubiquitin E3 complex scaffold protein,Cullin-3 in breast cancer cellsPrincipal Investigator

    • Principal Investigator
      Murakami Akari
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General surgery
    • Research Institution
      Ehime University

All 2021 2019 2018

All Journal Article Presentation

  • [Journal Article] CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP2021

    • Author(s)
      Nishiyama Kanako、Maekawa Masashi、Nakagita Tomoya、Nakayama Jun、Kiyoi Takeshi、Chosei Mami、Murakami Akari、Kamei Yoshiaki、Takeda Hiroyuki、Takada Yasutsugu、Higashiyama Shigeki
    • Journal Title

      Life Science Alliance

      Volume: 4 Issue: 9 Pages: e202101095-e202101095

    • DOI

      10.26508/lsa.202101095

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18029, KAKENHI-PROJECT-19K18030, KAKENHI-PUBLICLY-21H00286, KAKENHI-PROJECT-21H02763, KAKENHI-PROJECT-20K05709
  • [Journal Article] Cullin‐3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2‐positive breast cancer cells2019

    • Author(s)
      Murakami Akari、Maekawa Masashi、Kawai Katsuhisa、Nakayama Jun、Araki Nobukazu、Semba Kentaro、Taguchi Tomohiko、Kamei Yoshiaki、Takada Yasutsugu、Higashiyama Shigeki
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 2 Pages: 650-661

    • DOI

      10.1111/cas.13899

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06831, KAKENHI-PROJECT-16H04698, KAKENHI-PROJECT-17K16510, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05903
  • [Presentation] A novel mechanism of phosphatase activation for EGFR by Cullin-3/KCTD10 ubiquitin E3 complex in HER-2-positive breast cancer cells.2021

    • Author(s)
      Ⅴ-1)Nishiyama K, Maekawa M, Murakami A, Utsunomiya K, Takemoto K, Kusakabe E, Noda H, Aoki R, Taguchi K, Yamashita M, Nakagita T, Nakayama J, Chosei M, Kiyoi T, Kamei Y, Takeda H, Takada Y, Higashiyama S
    • Organizer
      The 2021 San Antonio Breast Cancer Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18029
  • [Presentation] HER2陽性乳癌細胞におけるEGFRフォスファターゼ活性化の新規メカニズム2021

    • Author(s)
      Ⅶ-44)西山加那子、前川大志、中山 淳、村上朱里、亀井義明、高田泰次、東山繁
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K18029
  • [Presentation] HER2陽性乳癌細胞株における恒常的なRhoBタンパク質分解の生理機能の解析2021

    • Author(s)
      Ⅶ-27)西山加那子、村上朱里、奥島久美子、竹本佳菜、日下部恵梨菜、志田原智広、野田令菜、青木玲奈、田口加奈、山下美智子、亀井義明、高田泰次
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K18029
  • [Presentation] CUL3型ユビキチンE3複合体はHER2陽性乳癌細胞におけるEGF刺激依存的な細胞膜形態変化を抑制する2018

    • Author(s)
      村上朱里,、前川大志,、川合克久、荒木伸一、中山淳、 仙波憲太郎、田口友彦、亀井義明、高田泰次、東山繁樹
    • Organizer
      第59回日本生化学  中国・四国支部例会
    • Data Source
      KAKENHI-PROJECT-17K16510
  • [Presentation] Novel mechanisms of Rac1 activation by the cullin-3/KCTD10 ubiquitin E3 complex in HER2-positive breast cancer.2018

    • Author(s)
      Akari Murakami, Masashi Maekawa, Katsuhisa Kawai, Jun Nakayama, Nobukazu Araki, Kentaro Semba, Tomohiko Taguchi, Yoshiaki Kamei, Yasutsugu Takada, Shigeki Higashiyama
    • Organizer
      San Antonio Breast Cancer Symposium
    • Data Source
      KAKENHI-PROJECT-17K16510
  • 1.  Maekawa Masashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  Kawai Katsuhisa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  Nakayama Jun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  Araki Nobukazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  Semba Kentaro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  Taguchi Tomohiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  Kamei Yoshiaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  Takada Yasutsugu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  Higashiyama Shigeki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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