MOTOSHIMA Takanobu 元島崇信

Researcher Number	60726355
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2024: 熊本大学, 大学院生命科学研究部(医), 助教 2016: 熊本大学, 医学部附属病院, 助教 2015: 熊本大学, 医学部附属病院, 医員 2014: 熊本大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Urology / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 腎癌 / 免疫療法 / 腎細胞癌 / 免疫抑制 / 尿路上皮癌 / 免疫抑制機構 / 複合免疫療法 / サイトフ / マスサイトメトリー / 腎癌薬物療法 … More / 腫瘍免疫 / 免疫チェックポイント阻害薬 / Cytof / 免疫関連副作用 / TIMD4 / マクロファージ / 癌免疫 … More Except Principal Investigator マクロファージ / CD169 / 腫瘍免疫 / 腎癌 / バイオマーカー / 癌 / 抗原提示 / がん免疫療法 / CD8陽性リンパ球 / CD169陽性リンパ洞性マクロファージ / 免疫チェックポイント阻害剤 / ナリンジン / irAE肺臓炎 / 抗CD74自己抗体 / 肺臓炎 / サイトカイン / ケモカイン / CXCL13 / 免疫関連副作用 / 自己抗体 / CD74 / CXCL10 / 免疫チェックポイント阻害薬 / 免疫関連有害事象 / 腎細胞癌 / ３次元培養 / 質量分析 / 3次元培養 / 新規標的分子 / VHL / 薬剤感受性 / ctDNA / 前立腺癌 / 循環腫瘍DNA / 循環腫瘍細胞 / cfDNA / CTC / 免疫学 Less

Analysis of lymph node antigen-presenting cells and regulation of their activation; toward development of novel cancer immunotherapy
- Principal Investigator
  
  矢津田旬二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kumamoto University
Elucidating the relationship between autoantibodies and immune cell activation in immune-related adverse events induced by immune checkpoint inhibitors
- Principal Investigator
  
  Miura Yuji
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okinaka Memorial Institute for Medical Research
Integrated Analysis of Intratumoral and Systemic Immune Environment in Renal Cell Carcinoma and Urothelial CarcinomaPrincipal Investigator
- Principal Investigator
  
  Motoshima Takanobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kumamoto University
Development of new cancer immunotherapy focusing on lymph node antigen-presenting cells
- Principal Investigator
  
  Yatsuda Junji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kumamoto University
Exploring novel downstream targets of VBC-Cul2 complex in clear cell renal cell carcinoma
- Principal Investigator
  
  Kamba Tomomi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kumamoto University
Analyzation of anticancer drug resistance mechanism focusing on macrophage related molecules in renal cancerPrincipal Investigator
- Principal Investigator
  
  Motoshima Takaonobu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kumamoto University
Development of predictive markers for drug-susceptibility in blood by genomic analysis using PDX models
- Principal Investigator
  
  Kamba Tomomi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kumamoto University
  Kyoto University
Development of a new treatment method against renal cancer using immune checkpoint inhibitors
- Principal Investigator
  
  Eto Masatoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Kyushu University
  Kumamoto University

All 2023 2022 2021 2020 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Predictive value of CXCL10 for the occurrence of immune‐related adverse events in patient with renal cell carcinoma2023
- Author(s)
  Miura Yuji、Motoshima Takanobu、Anami Toshiki、Yano Hiromu、Mito Remi、Pan Cheng、Urakami Shinji、Kinowaki Keiichi、Tsukamoto Hirotake、Kurahashi Ryoma、Murakami Yoji、Yatsuda Junji、Fujiwara Yukio、Kamba Tomomi、Komohara Yoshihiro
- Journal Title
  
  Microbiology and Immunology
  
  Volume: Online ahead of print. Issue: 7 Pages: 345-354
- DOI
  10.1111/1348-0421.13067
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09560, KAKENHI-PROJECT-23K06362, KAKENHI-PROJECT-20K07669, KAKENHI-PROJECT-20K16450, KAKENHI-PROJECT-21H02788
[Journal Article] Aging-associated and CD4 T-cell-dependent ectopic CXCL13 activation predisposes to anti?PD-1 therapy-induced adverse events2022
- Author(s)
  Tsukamoto Hirotake、Komohara Yoshihiro、Tomita Yusuke、Miura Yuji、Motoshima Takanobu、Imamura Kosuke、Kimura Toshiki、Ikeda Tokunori、Fujiwara Yukio、Yano Hiromu、Kamba Tomomi、Sakagami Takuro、Oshiumi Hiroyuki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 29
- DOI
  10.1073/pnas.2205378119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08541, KAKENHI-PROJECT-21H02788, KAKENHI-PROJECT-20K09560
[Journal Article] Efficacy of avelumab plus axitinib for advanced renal cell carcinoma as late-line therapy: A case report2022
- Author(s)
  Uekawa Ayano、Kurahashi Ryoma、Motoshima Takanobu、Murakami Yoji、Yatsuda Junji、Kamba Tomomi
- Journal Title
  
  Urology Case Reports
  
  Volume: 45 Pages: 102198-102198
- DOI
  10.1016/j.eucr.2022.102198
- Data Source
  KAKENHI-PROJECT-20K09560
[Journal Article] Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide?chlorambucil conjugate2022
- Author(s)
  Funasaki Shintaro、Mehanna Sally、Ma Wenjuan、Nishizawa Hidekazu、Kamikubo Yasuhiko、Sugiyama Hiroshi、Ikeda Shuji、Motoshima Takanobu、Hasumi Hisashi、Linehan W. Marston、Schmidt Laura S.、Ricketts Chris、Suda Toshio、Oike Yuichi、Kamba Tomomi、Baba Masaya
- Journal Title
  
  Cancer Science
  
  Volume: n/a Issue: 7 Pages: 2352-2367
- DOI
  10.1111/cas.15364
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09694, KAKENHI-PROJECT-18H05284, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-20K09560, KAKENHI-PROJECT-21K19721, KAKENHI-PROJECT-21K09374, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-23K24474
[Journal Article] Subcapsular renal hematoma after ureterorenoscopy2022
- Author(s)
  Harada Narumi、Yatsuda Junji、Kurahashi Ryoma、Fukushima Yumi、Segawa Takuya、Motoshima Takanobu、Murakami Yoji、Yamaguchi Takahiro、Sugiyama Yutaka、Kamba Tomomi
- Journal Title
  
  IJU Case Reports
  
  Volume: 5 Issue: 4 Pages: 281-285
- DOI
  10.1002/iju5.12464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09560
[Journal Article] STAT3 polymorphism associates with mTOR inhibitor-induced interstitial lung disease in patients with renal cell carcinoma2022
- Author(s)
  Kazuhiro Yamamoto, Takeshi Ioroi, Kazuaki Shinomiya, et al.
- Journal Title
  
  Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  
  Volume: - Issue: 1 Pages: 11-23
- DOI
  10.3727/096504022x16418911579334
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07191, KAKENHI-PROJECT-19K07219, KAKENHI-PROJECT-20K09560
[Journal Article] Clear cell carcinoma of the seminal vesicle in a young adult2022
- Author(s)
  Murakami Hidetoshi、Motoshima Takanobu、Kurahashi Ryoma、Murakami Yoji、Sugiyama Yutaka、Yamaguchi Takahiro、Yatsuda Junji、Asato Tsuguharu、Mikami Yoshiki、Kamba Tomomi
- Journal Title
  
  IJU Case Reports
  
  Volume: 5 Issue: 5 Pages: 406-409
- DOI
  10.1002/iju5.12502
- Data Source
  KAKENHI-PROJECT-20K09560
[Journal Article] High T-cell infiltration in tumor tissue and younger age predict the response to pembrolizumab in recurrent urothelial cancer2021
- Author(s)
  Anami, Toshiki Komohara, Yoshihiro Miura, Yuji Yamanaka, Kotaro Kurahashi, Ryoma Segawa, Takuya Motoshima, Takanobu Murakami, Yoji Yatsuda, Junji Yamaguchi, Takahiro Sugiyama, Yutaka Jinnouchi, Yoshiteru Kamba, Tomomi
- Journal Title
  
  Med Mol Morphol
  
  Volume: 54 Issue: 4 Pages: 316-323
- DOI
  10.1007/s00795-021-00292-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09560
[Journal Article] HLA-DR and CD74 Expression and the Immune Microenvironment in Renal Cell Carcinoma2021
- Author(s)
  Miura, Y. Anami, T. Yatsuda, J. Motoshima, T. Oka, S. Suyama, K. Inoshita, N. Kinowaki, K. Urakami, S. Kamba, T. Komohara, Y.
- Journal Title
  
  Anticancer Res
  
  Volume: 41 Issue: 6 Pages: 2841-2848
- DOI
  10.21873/anticanres.15065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09560
[Journal Article] Remarkable antitumor effect of nivolumab in a patient with metastatic renal cell carcinoma previously treated with a peptide‐based vaccine2020
- Author(s)
  Kurahashi Ryoma、Motoshima Takanobu、Fukushima Yumi、Murakami Yoji、Yatsuda Junji、Yamaguchi Takahiro、Sugiyama Yutaka、Fukushima Satoshi、Komohara Yoshihiro、Suekane Shigetaka、Kamba Tomomi
- Journal Title
  
  IJU Case Reports
  
  Volume: 3 Issue: 2 Pages: 44-48
- DOI
  10.1002/iju5.12139
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09182, KAKENHI-PROJECT-20K09560
[Journal Article] Phenotypical change of tumor-associated macrophages in metastatic lesions of clear cell renal cell carcinoma2018
- Author(s)
  Motoshima Takanobu、Miura Yuji、Wakigami Nanako、Kusada Natsuki、Takano Toshimi、Inoshita Naoko、Okaneya Toshikazu、Sugiyama Yutaka、Kamba Tomomi、Takeya Motohiro、Komohara Yoshihiro
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 51 Issue: 1 Pages: 57-63
- DOI
  10.1007/s00795-017-0174-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K11013, KAKENHI-PROJECT-16K15248
[Journal Article] Phenotypical change of tumor-associated macrophages in metastatic lesions of clear cell renal cell carcinoma.2018
- Author(s)
  1.Motoshima T, Miura Y, Wakagami N, Kusada N, Takano T, Inoshita N, Okaneya T, Sugiyama Y, Kamba T, Takeya M, Komohara Y
- Journal Title
  
  Med Mol Morphol.
  
  Volume: 51 Pages: 57-63
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11013
[Journal Article] CD163-positive cancer cells are potentially associated with high malignant potential in clear cell renal cell carcinoma2018
- Author(s)
  Ma Chaoya、Horlad Hasita、Ohnishi Koji、Nakagawa Takenobu、Yamada Sohsuke、Kitada Shohei、Motoshima Takanobu、Kamba Tomomi、Nakayama Toshiyuki、Fujimoto Naohiro、Takeya Motohiro、Komohara Yoshihiro
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 51 Issue: 1 Pages: 13-20
- DOI
  10.1007/s00795-017-0165-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K11013, KAKENHI-PROJECT-16K15248
[Journal Article] The significance of TIMD4 expression in clear cell renal carcinoma.2017
- Author(s)
  3.Hiromu Yano, Takanobu Motoshima, Chaoya Ma, Cheng Pan, Sohsuke Yamada, Toshiyuki Nakayama, Shohei Kitada, Naohiro Fujimoto, Tomomi Kamba, Motohiro Takeya, Yoshihiro Komohara.
- Journal Title
  
  Med Mol Morphol
  
  Volume: 50 Pages: 220-226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11013
[Journal Article] Contrasting effects of cyclophosphamide onanti-CTL-associated protein 4 blockade therapy intwo mouse tumor models.2017
- Author(s)
  2.Yuichi Iida, Nanae Harashima, Takanobu Motoshima, Yoshihiro Komohara, Masatoshi Eto and Mamoru Harada.
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Pages: 1974-1984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11013
[Journal Article] PD-L1 expression in papillary renal cell carcinoma2017
- Author(s)
  Takanobu Motoshima, Yoshihiro KomoharaEmail author, Chaoya Ma, Arni Kusuma Dewi, Hirotsugu Noguchi, Sohsuke Yamada, Toshiyuki Nakayama, Shohei Kitada, Yoshiaki Kawano, Wataru Takahashi, Masaaki Sugimoto, Motohiro Takeya, Naohiro Fujimoto, Yoshinao Oda and Masatoshi Eto
- Journal Title
  
  BMC Urology
  
  Volume: 17 Issue: 1 Pages: 8-8
- DOI
  10.1186/s12894-016-0195-x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11013, KAKENHI-PROJECT-16K15248, KAKENHI-PROJECT-17H04060
[Journal Article] CXCL10 and CCL2 mRNA expression in monocytes is inversely correlated with the HLA-DR lower fraction of monocytes in patients with renal cell carcinoma.2016
- Author(s)
  Motoshima T, Komohara Y, Horlad H, Tsukamoto H, Fujita M, Saito Y, Tanoue K, Kasejima Y, Sugiyama Y, Kawano Y, Nishimura Y, Takeya M, Eto M.
- Journal Title
  
  Oncol Lett.
  
  Volume: 11 Pages: 1911-1916
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670703
[Journal Article] Infiltration of tumor-associated macrophages is involved in CD44 expression in clear cell renal cell carcinoma.2016
- Author(s)
  Ma C, Komohara Y, Ohnishi K, Shimoji T, Kuwahara N, Sakumura Y, Matsuishi K, Fujiwara Y, Motoshima T, Takahashi W, Yamada S, Kitada S, Fujimoto N, Nakayama T, Eto M, Takeya M.
- Journal Title
  
  Cancer Sci.
  
  Volume: Epub Issue: 5 Pages: 700-707
- DOI
  10.1111/cas.12917
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670703, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-26460454, KAKENHI-PROJECT-16K09247
[Journal Article] Sorafenib enhances the anti-tumor effect of anti-CTLA-4 antibody by inhibiting myeloid-derived suppressor cells.2015
- Author(s)
  Motoshima T, Komohara Y, Horlad H, Takeuchi A, Maeda Y, Tanoue K, Kawano Y, Harada M, Takeya M, Eto M
- Journal Title
  
  Oncol Rep
  
  Volume: - Issue: 6 Pages: 2947-2953
- DOI
  10.3892/or.2015.3893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-26670703, KAKENHI-PROJECT-15K10596
[Presentation] 免疫チェックポイント阻害薬と分子標的薬併用療法の使用経験から学ぶこれからの使用方法の探索2023
- Author(s)
  元島　崇信
- Organizer
  第110回日本泌尿器科学会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] Predictive value of CXCL10 for the occurrence of immune related adverse events in patient with renal cell carcinoma2023
- Author(s)
  Yuji Miura; Takanobu Motoshima; Toshiki Anami; Hiromu Yano; Remi Mito; Shinji Urakami; Keiichi Kinowaki; Hirotake Tsukamoto; Ryoma Kurahashi; Yoji Murakami; Junji Yatsuda; Yukio Fujiwara; Tomomi Kamba; Yoshihiro Komohara
- Organizer
  American Association for Cancer Research, Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07669
[Presentation] Predictive biomarkers of response to immune checkpoint inhibitors in metastatic renal cell ca2023
- Author(s)
  TAKANOBU MOTOSHIMA, YUJI MIURA, TOSHIKI ANAMI, YOSHIHIRO KOMOHARA, SHIGEHISA KITANO, MASAYA BABA ,TOMOMI KAMBA
- Organizer
  2023AAACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] Antitumor effect of naringin, a natural compound, via activating CD169-positive macrophages in lymph nodes2022
- Author(s)
  shiki Anami, Yukio Fujiwara, Cheng Pan, Takanobu Motoshima, Junji Yatsuda, Yoshihiro Komohara, Tomomi Kamba
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-20K09579
[Presentation] 熊本大学病院における1st line Ipi-Nivo2022
- Author(s)
  元島　崇信、背川　卓也、倉橋　竜磨、村上　洋嗣、矢津田　旬二、杉山　豊、神波　大己
- Organizer
  第60回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] RAPNを施行して好酸性乳頭状腎細胞癌と診断された2例2022
- Author(s)
  元島崇信、原田成美、石﨑宏志、野尻拓矢、倉橋竜磨、福島結美脊川卓也、村上洋嗣、矢津田旬二、山口隆大、杉山豊、神波大己
- Organizer
  第10回日本泌尿器病理研究会学術集会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] ペムブロリズマブが著効してSurgical CRが得られた巨大腎細胞がんの1例2022
- Author(s)
  元島　崇信
- Organizer
  第10回日本臨床腫瘍学会九州地区セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 免疫チェックポイント阻害薬投与後に腎摘除術を行った2例2022
- Author(s)
  元島　崇信、倉橋　竜磨、矢津田　旬二、村上　洋嗣、脊川　卓也、杉山　豊、神波　大己
- Organizer
  第52回腎癌研究会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] Panel discussion on clinical cases: How do you treat this patient? Differences in approaches?2021
- Author(s)
  Takanobu Motoshima
- Organizer
  America Urology Association Annual Meeting 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 転移性腎細胞癌に対しては、薬物療法に先行して腎摘除術を行う事がまっとうか？　Upfront nephrectomy に対する疑問点2021
- Author(s)
  元島　崇信
- Organizer
  第73回西日本泌尿器科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 10次治療にカボザンチニブを導入して腫瘍縮小効果を示した進行性腎細胞癌の一例2021
- Author(s)
  元島　崇信、背川　卓也、倉橋　竜磨、村上　洋嗣、矢津田　旬二、杉山　豊、山口　隆大、神波　大己
- Organizer
  第7回日本泌尿器腫瘍学会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 熊本大学病院におけるかん複合免疫療法の治療効果と副作用の発現2021
- Author(s)
  元島　崇信、背川　卓也、倉橋　竜磨、村上　洋嗣、矢津田　旬二、杉山　豊、山口　隆大、西　一彦、神波　大己
- Organizer
  第59回日本がん治療学会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] これまでのエビデンスから進行腎癌の腫瘍減量手術を考える2021
- Author(s)
  元島　崇信
- Organizer
  第7回日本泌尿器腫瘍学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 熊本大学病院における進行性腎細胞癌に対するカボザンチニブ投与の初期経験2021
- Author(s)
  元島　崇信
- Organizer
  第109回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 生検で尿路上皮癌由来の癌肉腫と診断され、ペンブロリズマブが著効した嫌色素性腎細胞癌由来の癌肉腫の1例2021
- Author(s)
  元島崇信、野尻拓矢、倉橋竜磨、村上洋嗣、矢津田旬二、山口隆大、杉山豊、川上史、三上芳喜、神波大己
- Organizer
  第19回日本臨床腫瘍学会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 高齢女性に発症した転移性腎原発性神経内分泌腫瘍の一例2020
- Author(s)
  元島　崇信, 倉橋　竜磨, 村上　洋嗣, 矢津田　旬二, 山口　隆大, 杉山　豊, 神波　大己
- Organizer
  第9回日本泌尿器病理研究会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 熊本大学における分子標的薬の進行性腎癌に対する治療成績の検討2020
- Author(s)
  元島　崇信、穴見　俊樹、山中　広太郎、倉橋　竜磨、村上　洋嗣、矢津田　旬二、山口　隆大、杉山　豊、西　一彦、神波　大己
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 熊本大学病院におけるニボルマブとイピリムマブ併用療法の経験2020
- Author(s)
  元島　崇信、山中　広太郎、倉橋　竜磨、村上　洋嗣、矢津田　旬二、杉山　豊、山口　隆大、西　一彦、神波　大己
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09560
[Presentation] 進行性腎癌に対するNivolumab(Opdivo)投与の初期経験2018
- Author(s)
  元島　崇信、福島結美、矢津田旬二、村上洋嗣、山口隆大、田上憲一郎、杉山豊、神波大己
- Organizer
  第56回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] 去勢抵抗性前立腺癌に対する10コース以上ドセタキセルを投与した症例の検討2018
- Author(s)
  元島崇信、上園英太、山口隆大、神波大己
- Organizer
  第106回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] Characterization of chimeric TFE3 transcription factors found in Xp11.2 translocation renal cell carcinoma2018
- Author(s)
  Takanobu Motoshima, Yorifumi Satou, Paola Miyazato, Hisashi Hasumi, Ying Huang, Tsuyoshi Kadomatsu, Masahiro Yao, Yoji Nagashima, Mitsuko Furuya, Yuchi Oike, Laura S Schmidt, Tomomi Kamba, W Marston Linehan, Masaya Baba
- Organizer
  アメリカ泌尿器科学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] RAPNにおけるRENAL nephrometry scoreの意義2018
- Author(s)
  元島　崇信、福島結美、矢津田旬二、村上洋嗣、山口隆大、田上憲一郎、神波大己
- Organizer
  第32回泌尿器内視鏡学会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] 神経内分泌腫瘍（NET:neuroendocrine tumor）と診断された2症例2018
- Author(s)
  元島　崇信, 林　英孝, 福島　結美, 田上憲一郎, 神波大己
- Organizer
  日本泌尿器科学会　第197回熊本地方会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] 熊本大学におけるロボット支援下腎部分切除術（RAPN）の初期経験2018
- Author(s)
  元島　崇信、矢津田旬二、村上洋嗣、山口隆大、田上憲一郎、杉山豊、神波大己
- Organizer
  第49回腎癌研究会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] Characterization of chimeric TFE3 transcription factors found in Xp11.2 translocation renal cell carcinoma2017
- Author(s)
  元島崇信
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04973
[Presentation] TFE-3染色で陽性と診断された腎癌3症例のレトロスペクティブな解析2017
- Author(s)
  元島　崇信,西澤　秀和,馬場　理也,古谷　充子,加藤　生真,神波大己
- Organizer
  第55回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] TFE3活性化腎細胞癌の診断補助マーカーの探索と評価2017
- Author(s)
  元島崇信
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-15H04973
[Presentation] PD-L1/B7-H1 expression in papillary renal cell carcinoma2017
- Author(s)
  Takanobu Motoshima, Yoshihiro KomoharaEmail author, Chaoya Ma, Arni Kusuma Dewi, Hirotsugu Noguchi, Sohsuke Yamada, Toshiyuki Nakayama, Shohei Kitada, Yoshiaki Kawano, Wataru Takahashi, Masaaki Sugimoto, Motohiro Takeya, Naohiro Fujimoto, Yoshinao Oda and Masatoshi Eto
- Organizer
  Advanced in Urology 2017
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] 熊本大学における進行性前立腺癌に対するドセタキセル治療成績の検討2017
- Author(s)
  元島　崇信、上園　英太、山口　隆大、神波　大己
- Organizer
  第33回前立腺癌シンポジウム
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] TFE3活性化腎細胞癌の診断補助マーカーの探索と評価2017
- Author(s)
  元島崇信,馬場理也,蓮見壽史,加藤生真,長嶋洋治,黒田直人,高橋　渡,河野吉昭,矢尾正祐,江藤正俊,古屋充子,神波大己
- Organizer
  第105回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] Xp11転座型腎癌と診断された2症例のレトロスペクティブな解析2017
- Author(s)
  元島　崇信,西澤　秀和,馬場　理也,古谷　充子,加藤　生真,神波大己
- Organizer
  第48回腎癌研究会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] Characterization of chimeric TFE3 transcription factors found in Xp11.2 translocation renal cell carcinoma2017
- Author(s)
  元島崇信, 馬場理也,蓮見壽史, 黄瑩,佐藤賢文,宮里パオラ,門松　毅矢尾正祐,長嶋洋治,古屋充子,尾池雄一,神波大己,Laura S Schmidt, W Marston Linehan
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] 乳頭状腎細胞癌におけるPD-L1 発現についての検討2016
- Author(s)
  元島崇信、菰原義弘、野口紘嗣、山田壮亮、北田昇平、中山敏幸、竹屋元裕、江藤正俊
- Organizer
  第68回西日本泌尿器科学会総会
- Place of Presentation
  下関
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] 乳頭状腎細胞癌におけるPD-L1発現についての検討2016
- Author(s)
  元島崇信、菰原義弘、野口紘嗣、山田壮亮、北田昇平、中山敏幸、竹屋元裕、江藤正俊
- Organizer
  第104回日本泌尿器科学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] PD-L1 and PD-L2 expression in papillary renal cell carcinoma2016
- Author(s)
  Takanobu Motoshima, Yoshihiro KomoharaEmail author, Chaoya Ma, Arni Kusuma Dewi, Hirotsugu Noguchi, Sohsuke Yamada, Toshiyuki Nakayama, Shohei Kitada, Yoshiaki Kawano, Wataru Takahashi, Masaaki Sugimoto, Motohiro Takeya, Naohiro Fujimoto, Yoshinao Oda and Masatoshi Eto
- Organizer
  第2回日本泌尿器腫瘍学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] PD-L1 and PD-L2 expression in papillary renal cell carcinoma2016
- Author(s)
  Takanobu Motoshima, Yoshihiro KomoharaEmail author, Chaoya Ma, Arni Kusuma Dewi, Hirotsugu Noguchi, Sohsuke Yamada, Toshiyuki Nakayama, Shohei Kitada, Yoshiaki Kawano, Wataru Takahashi, Masaaki Sugimoto, Motohiro Takeya, Naohiro Fujimoto, Yoshinao Oda and Masatoshi Eto
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16K11013
[Presentation] マウス腎癌モデルにおける抗CTLA-4抗体と抗PD-1抗体の併用療法による抗腫瘍効果についての検討2014
- Author(s)
  元島崇信、菰原義弘、哈斯塔、河野吉昭、竹屋元裕、江藤正俊
- Organizer
  第45回腎癌研究会
- Place of Presentation
  品川インターシティホテル
- Year and Date
  2014-07-20
- Data Source
  KAKENHI-PROJECT-26670703
[Presentation] マウス腎癌モデルにおける抗CTLA-4抗体と抗PD-1抗体の併用療法による抗腫瘍効果についての検討.
- Author(s)
  元島崇信、菰原義弘、哈斯塔、河野吉昭、竹屋元裕、江藤正俊
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670703

1. Kamba Tomomi (20402836)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
2. 菰原義弘 (40449921)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
3. Yatsuda Junji (20749626)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
4. 村上洋嗣 (70735703)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 倉橋竜磨 (80867945)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
6. Miura Yuji (10453698)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. 馬場理也 (10347304)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 杉山豊 (40709292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
9. Eto Masatoshi (90315078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 河野吉昭 (30593793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 山崎俊成 (00607749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小林恭 (00642406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 寺田直樹 (60636637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 小川修 (90260611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中村英二郎 (90293878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 荒木令江 (80253722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 田辺裕子 (00743692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 新留琢郎 (20264210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. AWAI Hirotake

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 竹屋元裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. 末金茂高

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 大西紘二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. HORLAD Hasita

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 蓮見壽史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 山本和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MOTOSHIMA Takanobu 元島 崇信

Research Projects

Research Products

Co-Researchers

Analysis of lymph node antigen-presenting cells and regulation of their activation; toward development of novel cancer immunotherapy

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Elucidating the relationship between autoantibodies and immune cell activation in immune-related adverse events induced by immune checkpoint inhibitors

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Integrated Analysis of Intratumoral and Systemic Immune Environment in Renal Cell Carcinoma and Urothelial CarcinomaPrincipal Investigator

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Development of new cancer immunotherapy focusing on lymph node antigen-presenting cells

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Exploring novel downstream targets of VBC-Cul2 complex in clear cell renal cell carcinoma

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Analyzation of anticancer drug resistance mechanism focusing on macrophage related molecules in renal cancerPrincipal Investigator

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Development of predictive markers for drug-susceptibility in blood by genomic analysis using PDX models

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Development of a new treatment method against renal cancer using immune checkpoint inhibitors

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[Journal Article] Predictive value of CXCL10 for the occurrence of immune‐related adverse events in patient with renal cell carcinoma2023

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[Journal Article] Aging-associated and CD4 T-cell-dependent ectopic CXCL13 activation predisposes to anti?PD-1 therapy-induced adverse events2022

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[Journal Article] Efficacy of avelumab plus axitinib for advanced renal cell carcinoma as late-line therapy: A case report2022

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[Journal Article] Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide?chlorambucil conjugate2022

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[Journal Article] Subcapsular renal hematoma after ureterorenoscopy2022

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[Journal Article] STAT3 polymorphism associates with mTOR inhibitor-induced interstitial lung disease in patients with renal cell carcinoma2022

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MOTOSHIMA Takanobu 元島崇信