Matsumoto Kazuaki 松元一明

… Alternative Names

MATSUMOTO Kazuaki 松元一明

Less

Researcher Number	60733160
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 薬学部(芝共立), 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 慶應義塾大学, 薬学部(芝共立), 教授 2016: 慶應義塾大学, 薬学部(芝共立), 准教授 2015: 慶應義塾大学, 薬学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator PK/PD / β-ラクタム系抗菌薬 / PK/PD評価 / 肺MABC症 / βラクタム系抗菌薬 / DBO系βラクタマーゼ阻害薬 / HFIM / 肺MABC症マウスモデル / 耐性菌感染症 / ラタモキセフ … More / ESBL産生菌 / マウス大腿部感染モデル / セフメタゾール / フロモキセフ / ESBL産生大腸菌 / 化膿性髄膜炎 / 血液透析濾過 / 特殊病態 / 抗菌薬 … More Except Principal Investigator 骨髄炎 / MRSA感染 / テジゾリドリン酸エステル / PK/PD解析 / 母集団薬物動態解析 / TDM / 組織内薬物動態 / MRSA / テジゾリド Less

Development of novel pulmonary MABC therapies and innovative preclinical PK/PD evaluation methodsPrincipal Investigator
- Principal Investigator
  
  松元一明
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Keio University
Establishment of an Optimized Tedizolid Administration Protocol for the Treatment of MRSA Bone Infections
- Principal Investigator
  
  Watanabe Yoshinobu
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Teikyo University
Development of individually optimized dosing regimen for antimicrobial agents aiming at overcoming antimicrobial-resistant bacterial infectionsPrincipal Investigator
- Principal Investigator
  
  Matsumoto Kazuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Keio University
The Development of optimal dosage of anti-microbial agents based on PK/PD in patients with special pathological conditionsPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Kazuaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University

All 2025 2024 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Combined dual β-lactams and diazabicyclooctane β-lactamase inhibitor is highly effective against Mycobacterium abscessus species in vitro2025
- Author(s)
  Misawa Kana、Nishimura Tomoyasu、Yoshikawa Maiko、Shimamura Rina、Kashimura Shoko、Enoki Yuki、Taguchi Kazuaki、Matsumoto Kazuaki、Hasegawa Naoki
- Journal Title
  
  Journal of Global Antimicrobial Resistance
  
  Volume: 42 Pages: 142-150
- DOI
  10.1016/j.jgar.2025.02.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02199, KAKENHI-PROJECT-23K07951
[Journal Article] Simulated achievement rate of β-lactams/nacubactam treatment in humans using instantaneous MIC-based PK/PD analysis2025
- Author(s)
  Igarashi Yuki、Taguchi Kazuaki、Enoki Yuki、Chuang Victor Tuan Giam、Matsumoto Kazuaki
- Journal Title
  
  Journal of Antimicrobial Chemotherapy
  
  Volume: 80 Issue: 2 Pages: 547-553
- DOI
  10.1093/jac/dkae443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02199
[Journal Article] Development of a pharmacokinetic/pharmacodynamic evaluation model for osteomyelitis and usefulness of tedizolid as an alternative to vancomycin against MRSA osteomyelitis2025
- Author(s)
  Liu Xiaoxi、Enoki Yuki、Taguchi Kazuaki、Matsumoto Kazuaki
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 77 Issue: 2 Pages: 291-298
- DOI
  10.1093/jpp/rgae124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K02199
[Journal Article] Development and validation of a population pharmacokinetic model of vancomycin for patients of advanced age2025
- Author(s)
  Takada Keisuke、Samura Masaru、Matsumoto Kazuaki (23名中23番目) et al
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 11 Issue: 1 Pages: 18
- DOI
  10.1186/s40780-025-00423-8
- URL
  https://marianna-u.repo.nii.ac.jp/records/2001036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02199
[Journal Article] In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases2025
- Author(s)
  Hayashi Kengo、Suzuki Masahiro、Ishii Yoshikazu、Matsumura Yasufumi、Matsumoto Kazuaki、Saito Sho、Doi Yohei
- Journal Title
  
  Journal of Global Antimicrobial Resistance
  
  Volume: 42 Pages: 73-79
- DOI
  10.1016/j.jgar.2025.02.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02199
[Journal Article] Investigating the hypothermic effects of fluoroquinolone antimicrobials on non-bacterial fever model mice2024
- Author(s)
  Hara Ryohei、Taguchi Kazuaki、Ogino Hiromi、Okamoto Yuko、Enoki Yuki、Kizu Junko、Hori Seiji、Matsumoto Kazuaki
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 10 Issue: 1 Pages: 68-68
- DOI
  10.1186/s40780-024-00392-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02199
[Journal Article] Pharmacokinetic/pharmacodynamic evaluation of flomoxef against extended-spectrum beta-lactamase-producing Escherichia coli in vitro and in vivo in a murine thigh infection model.2021
- Author(s)
  Sho Tashiro, Marina Hayashi, Wataru Takemura, Yuki Igarashi, Xiaoxi Liu, Yuki Mizukami, Nana Kojima, Yuki Enoki, Kazuaki Taguchi, Yuta Yokoyama, Tomonori Nakamura, Kazuaki Matsumoto.
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 38 Issue: 1 Pages: 27-35
- DOI
  10.1007/s11095-020-02977-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06795
[Journal Article] Dosing optimization of meropenem based on a pharmacokinetic analysis in patients receiving hemodiafiltration and an in vitro model2018
- Author(s)
  Yokoyama Yuta、Nishino Kakine、Matsumoto Kazuaki、Inomoto Yuki、Matsuda Kaori、Nakamura Rin-nosuke、Yasuno Nobuhiro、Kizu Junko
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 24 Issue: 2 Pages: 92-98
- DOI
  10.1016/j.jiac.2017.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08105
[Presentation] Mycobacterium aviumとMycobacterium intracellulareの臨床分離株を用いたβ-ラクタム系抗菌薬2剤併用の有効性評価.2024
- Author(s)
  吉川万衣子、西村知泰、三澤可奈、島村莉奈、鈴木健太、柏村祥子、榎木裕紀、田口和明、松元一明.
- Organizer
  第55回結核・非定型抗酸菌症治療研究会
- Data Source
  KAKENHI-PROJECT-24K02199
[Presentation] 抗菌薬曝露時におけるMycobacterium abscessusのコロニー形態変化.2024
- Author(s)
  島村莉奈、西村知泰、三澤可奈、吉川万衣子、柏村祥子、矢野大和、矢野郁也、榎木裕紀、田口和明、松元一明、長谷川直樹.
- Organizer
  第55回結核・非定型抗酸菌症治療研究会
- Data Source
  KAKENHI-PROJECT-24K02199
[Presentation] Hollow Fiber Infection Modelを用いたメタロβラクタマーゼ産生菌に対するレレバクタム/イミペネム/アズトレオナムの併用効果.2024
- Author(s)
  鈴木健太、林侑孝、山口哲央、柏木克仁、加村（中川）晴香、齋藤翔、榎木裕紀、田口和明、舘田一博、石井良和、松元一明.
- Organizer
  第98回日本感染症学会学術講演会／第72回日本化学療法学会総会合同学会
- Data Source
  KAKENHI-PROJECT-24K02199
[Presentation] Hollow Fiber Infection Modelを用いた抗感染症薬のin vitro PK/PD評価.2024
- Author(s)
  林侑孝、松元一明.
- Organizer
  第73回日本感染症学会東日本地方会学術集会／第71回日本化学療法学会東日本支部総会合同学会
- Data Source
  KAKENHI-PROJECT-24K02199
[Presentation] In vivoおよびIn vitro感染モデルを用いた腸球菌感染症に対するバンコマイシンのPK/PD評価.2024
- Author(s)
  林侑孝、髙橋実秀、佐々木萌、劉小茜、榎木裕紀、田口和明、松元一明.
- Organizer
  第36回微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-24K02199
[Presentation] In vitro及びin vivoマウス大腿部感染モデルを用いた基質特異性拡張型β-ラクタマーゼ産生大腸菌に対する既存抗菌薬のpharmacokinetics/pharmacodynamics評価.2021
- Author(s)
  田代渉, 松元一明.
- Organizer
  日本薬学会第141年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06795
[Presentation] 耐性菌治療における効果的な投与方法2020
- Author(s)
  松元一明.
- Organizer
  第33回日本外科感染症学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06795
[Presentation] オキサセフェム系抗菌薬2020
- Author(s)
  田代渉, 林茉里奈, 五十嵐裕貴, 劉小茜, 竹村渉, 榎木裕紀, 田口和明, 横山雄太, 中村智徳, 松元一明.
- Organizer
  第68回日本化学療法学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06795
[Presentation] 好中球減少マウス大腿部感染モデルを用いたESBL産生大腸菌に対するflomoxefのPK/PD評価.2020
- Author(s)
  田代渉, 林茉里奈, 五十嵐裕貴, 劉小茜, 竹村渉, 榎木裕紀, 田口和明, 横山雄太, 中村智徳, 松元一明.
- Organizer
  第68回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-18K06795
[Presentation] マウスにおけるCefmetazoleの薬物動態解析.2020
- Author(s)
  竹村渉, 林茉里奈, 田代渉, 五十嵐裕貴, 劉小茜, 榎木裕紀, 田口和明, 横山雄太, 中村智徳, 松元一明.
- Organizer
  第68回日本化学療法学会総会
- Data Source
  KAKENHI-PROJECT-18K06795
[Presentation] ESBL産生菌感染症治療up to date2019
- Author(s)
  松元一明
- Organizer
  第29回日本医療薬学年会
- Data Source
  KAKENHI-PROJECT-18K06795
[Presentation] オキサセフェム系薬、セファマイシン系薬2018
- Author(s)
  松元一明
- Organizer
  第67回日本感染症学会東日本地方会学術集会/第65回日本化学療法学会東日本支部総会
- Data Source
  KAKENHI-PROJECT-18K06795
[Presentation] ダプトマイシンのHPLCを用いた血漿中濃度測定法に関する検討予測の可能性2017
- Author(s)
  田島彩子、松元一明
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-15K08105
[Presentation] オンライン血液濾過透析時におけるセファゾリン最適投与法の検討2017
- Author(s)
  土生章太郎、横山雄太、松元一明、安野伸浩、木津純子
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-15K08105
[Presentation] In vitroモデルを用いたメロペネムの血液透析濾過クリアランス予測の可能性.2016
- Author(s)
  横山雄太、松元一明、木津純子.
- Organizer
  第65回日本感染症学会東日本地方会学術集会/第63回日本化学療法学会東日本支部総会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K08105
[Presentation] 腎機能障害時（透析時）の抗菌薬投与2015
- Author(s)
  松元一明
- Organizer
  第64回日本感染症学会東日本地方会学術集会/第62回日本化学療法学会東日本支部総会
- Place of Presentation
  ロイトン札幌(北海道札幌市）
- Year and Date
  2015-10-21
- Data Source
  KAKENHI-PROJECT-15K08105

1. Watanabe Yoshinobu (00295651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 乾貴博 (10724213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 安野伸浩 (20463870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 宮本亘 (30437553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 安井洋一 (80527466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 西村知泰 (90348649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Matsumoto Kazuaki 松元 一明

MATSUMOTO Kazuaki 松元 一明

Research Projects

Research Products

Co-Researchers

Development of novel pulmonary MABC therapies and innovative preclinical PK/PD evaluation methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of an Optimized Tedizolid Administration Protocol for the Treatment of MRSA Bone Infections

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of individually optimized dosing regimen for antimicrobial agents aiming at overcoming antimicrobial-resistant bacterial infectionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Development of optimal dosage of anti-microbial agents based on PK/PD in patients with special pathological conditionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Combined dual β-lactams and diazabicyclooctane β-lactamase inhibitor is highly effective against Mycobacterium abscessus species in vitro2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simulated achievement rate of β-lactams/nacubactam treatment in humans using instantaneous MIC-based PK/PD analysis2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a pharmacokinetic/pharmacodynamic evaluation model for osteomyelitis and usefulness of tedizolid as an alternative to vancomycin against MRSA osteomyelitis2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development and validation of a population pharmacokinetic model of vancomycin for patients of advanced age2025

Author(s)

Journal Title

DOI

URL

Data Source

[Journal Article] In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigating the hypothermic effects of fluoroquinolone antimicrobials on non-bacterial fever model mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacokinetic/pharmacodynamic evaluation of flomoxef against extended-spectrum beta-lactamase-producing Escherichia coli in vitro and in vivo in a murine thigh infection model.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dosing optimization of meropenem based on a pharmacokinetic analysis in patients receiving hemodiafiltration and an in vitro model2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mycobacterium aviumとMycobacterium intracellulareの臨床分離株を用いたβ-ラクタム系抗菌薬2剤併用の有効性評価.2024

Author(s)

Organizer

Data Source

[Presentation] 抗菌薬曝露時におけるMycobacterium abscessusのコロニー形態変化.2024

Author(s)

Organizer

Data Source

[Presentation] Hollow Fiber Infection Modelを用いたメタロβラクタマーゼ産生菌に対するレレバクタム/イミペネム/アズトレオナムの併用効果.2024

Author(s)

Matsumoto Kazuaki 松元一明

MATSUMOTO Kazuaki 松元一明