Murakami Kosuke 村上幸祐

Researcher Number	60734671
Other IDs	https://orcid.org/0000-0003-4278-5849
Affiliation (Current)	2025: 近畿大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 近畿大学, 医学部, 講師 2020 – 2023: 近畿大学, 医学部, 講師 2018 – 2019: 近畿大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 卵巣がん / 腫瘍免疫 / PD-L1 / IL-17 / IL-6 / 卵巣明細胞癌 / CD4 / RORC / 免疫チェックポイント阻害薬 / Th17 … More / 卵巣明細胞がん / PVR / PVRIG / マクロファージ / PVRL2 / 高異型度漿液性がん / 宿主免疫応答 / 免疫療法 / 近交系マウスモデル / 明細胞がん / 近交系マウス / マウスモデル / 卵巣癌 … More Except Principal Investigator 遺伝子変異 / ゲノムプロファイル解析 / 内膜症関連癌 / 子宮内膜 / CTNNB1 / KRAS / PIK3CA / 腫瘍内不均一性 / 類内膜がん / 卵巣がん / 卵巣明細胞癌 / PIK3CA変異 / 遺伝子変異解析 / 内膜症関連卵巣癌 / 子宮内膜症 / 卵巣癌 / 超常磁性酸化鉄製剤 / リンパ節転移診断 / 超常磁性酸化鉄(SPIO) / 鉄染色 / センチネルリンパ節 / リンパ節転移 / SPIO造影MRI / 超常磁性酸化鉄（SPIO） Less

卵巣明細胞がんのVEGF経路がもたらす腫瘍免疫微小環境の変化と新規治療の探索Principal Investigator
- Principal Investigator
  
  村上幸祐
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kindai University
Exploring immune checkpoint pathways as novel therapeutic targets in ovarian cancerPrincipal Investigator
- Principal Investigator
  
  村上幸祐
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kindai University
Probing intratumor heterogeneity and elucidating developmental mechanisms based on cancer-associated genetic mutations in ovarian endometrial carcinoma
- Principal Investigator
  
  貫戸明子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kindai University
卵巣明細胞がんの腫瘍免疫機構の解明と新たな免疫療法の探索Principal Investigator
- Principal Investigator
  
  村上幸祐
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kindai University
Investigation of the mechanism of development and preventive method for endometriosis-associated ovarian cancer
- Principal Investigator
  
  Matsumura Noriomi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kindai University
Establishment of inbred murine model of ovarian clear cell carcinoma and analysis of host immune responsePrincipal Investigator
- Principal Investigator
  
  Murakami Kosuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kindai University
Development of diagnosis of lymph node metastasis in uterine cancer by superparamagnetic iron oxide
- Principal Investigator
  
  SUZUKI Ayako
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kindai University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Uterine angioleiomyoma with disseminated intravascular coagulation: a case report2023
- Author(s)
  Hanako Sato, Kosuke Murakami, Risa Fujishima, Tomoyuki Otani, Kazuko Sakai, Kazuto Nishio, Noriomi Matsumura
- Journal Title
  
  BMC Women's Health
  
  Volume: 23 Issue: 1 Pages: 157-157
- DOI
  10.1186/s12905-023-02292-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16868, KAKENHI-PROJECT-20K21665
[Journal Article] Tubulovillous adenoma with high-grade dysplasia of the vulva harboring high tumor mutational burden and cancer-associated mutations: a case report2022
- Author(s)
  Sato Hanako、Murakami Kosuke、Otani Tomoyuki、Matsumura Noriomi
- Journal Title
  
  Diagnostic Pathology
  
  Volume: 17 Issue: 1 Pages: 85-85
- DOI
  10.1186/s13000-022-01268-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
[Journal Article] B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression2022
- Author(s)
  Miyamoto T, Murakami R, Hamanishi J, Tanigaki K, Hosoe Y, Mise N, Takamatsu S, Mise Y, Ukita M, Taki M, Yamanoi K, Horikawa N, Abiko K, Yamaguchi K, Baba T, Matsumura N, Mandai M.
- Journal Title
  
  Cancer Immunol Res .
  
  Volume: 10 Issue: 1 Pages: 56-69
- DOI
  10.1158/2326-6066.cir-21-0407
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09287, KAKENHI-PROJECT-20K18210, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-21J15178, KAKENHI-PROJECT-20K07319, KAKENHI-PROJECT-21K09548, KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-20K16431
[Journal Article] Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamics2022
- Author(s)
  Konishi I, Abiko K, Hayashi T, Yamanoi K, Murakami R, Yamaguchi K, Hamanishi J, Baba T, Matsumura N, Mandai M; Kyoto Study Group for Ovarian Cancer Research.
- Journal Title
  
  J Gynecol Oncol
  
  Volume: 33(5) Issue: 5
- DOI
  10.3802/jgo.2022.33.e83
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09548, KAKENHI-PROJECT-20K16431, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
[Journal Article] Ovarian teratoid carcinosarcoma with a PIK3CA mutation: a case report and review of the literature.2022
- Author(s)
  Masato Aoki,　Hisamitsu Takaya, Tomoyuki Otani, Hidekatsu Nakai, Kosuke Murakami, Noriomi Matsumura.
- Journal Title
  
  Int Cancer Conf J.
  
  Volume: 11 Issue: 4 Pages: 231-237
- DOI
  10.1007/s13691-022-00571-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09630, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
[Journal Article] PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma2021
- Author(s)
  Kitamura S, Yamaguchi K, Murakami R, Furutake Y, Higasa K, Abiko K, Hamanishi J, Baba T, Matsumura N, Mandai M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 112 Issue: 11 Pages: 4627-4640
- DOI
  10.1111/cas.15125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09287, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-21K09548, KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-23K21722
[Journal Article] Combination of gene set signatures correlates with response to nivolumab in platinum-resistant ovarian cancer2021
- Author(s)
  Murakami R, Hamanishi J, Brown JB, Abiko K, Yamanoi K, Taki M, Hosoe Y, Yamaguchi K, Baba T, Matsumura N, Konishi I, Mandai M.
- Journal Title
  
  Sci Rep .
  
  Volume: 11 Issue: 1 Pages: 11427-11427
- DOI
  10.1038/s41598-021-91012-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09287, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-21K09548, KAKENHI-PROJECT-20K21665
[Journal Article] Tumor Immune Microenvironment during Epithelial-Mesenchymal Transition.2021
- Author(s)
  Taki M, Abiko K, Ukita M, Murakami R, Yamanoi K, Yamaguchi K, Hamanishi J, Baba T, Matsumura N, Mandai M.
- Journal Title
  
  Clin Cancer Res
  
  Volume: - Issue: 17 Pages: 4459-4459
- DOI
  10.1158/1078-0432.ccr-20-4459
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-18H02945, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-18K09287, KAKENHI-PROJECT-20K16431
[Journal Article] Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma2021
- Author(s)
  Murakami Kosuke、Kanto Akiko、Sakai Kazuko、Miyagawa Chiho、Takaya Hisamitsu、Nakai Hidekatsu、Kotani Yasushi、Nishio Kazuto、Matsumura Noriomi
- Journal Title
  
  Modern Pathology
  
  Volume: 34 Issue: 11 Pages: 2071-2079
- DOI
  10.1038/s41379-021-00861-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
[Journal Article] A case report of bladder and intestinal endometriosis, and the relationship between sex hormone receptor expression and PIK3CA mutation analysis.2021
- Author(s)
  Kanto A, Kotani Y, Murakami K, Miyagawa C, Nakai H, Matsumura N.
- Journal Title
  
  BMC Womens Health
  
  Volume: 21 Issue: 1 Pages: 118-118
- DOI
  10.1186/s12905-021-01269-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-18H02947
[Journal Article] Characterization of patients that can continue conservative treatment for adenomyosis2021
- Author(s)
  Miyagawa Chiho、Murakami Kosuke、Tobiume Takako、Nonogaki Takafumi、Matsumura Noriomi
- Journal Title
  
  BMC Women's Health
  
  Volume: 21 Issue: 1 Pages: 431-431
- DOI
  10.1186/s12905-021-01577-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
[Journal Article] Endometriosis-Associated Ovarian Cancer: The Origin and Targeted Therapy.2020
- Author(s)
  Murakami K, Kotani Y, Nakai H, Matsumura N.
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 6 Pages: 1676-1676
- DOI
  10.3390/cancers12061676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-18H02947
[Journal Article] Effectiveness of laparoscopic ultrasonography in laparoscopic myomectomy.2020
- Author(s)
  Shigeta M, Kotani Y, Fujishima R, Yo Y, Murakami K, Takaya H, Nakai H, Suzuki A, Tsuji I, Matsumura N
- Journal Title
  
  Asian J Endosc Surg
  
  Volume: 13 Issue: 2 Pages: 200-204
- DOI
  10.1111/ases.12728
- Data Source
  KAKENHI-PROJECT-18K09241
[Journal Article] Superparamagnetic iron oxide as a tracer for sentinel lymph node detection in uterine cancer: a pilot study.2020
- Author(s)
  Murakami K, Kotani Y, Suzuki A, Takaya H, Nakai H, Matsuki M, Sato T, Mandai M, Matsumura N.
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 7945-7945
- DOI
  10.1038/s41598-020-64926-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-18K09241
[Journal Article] Differential Diagnosis of Uterine Leiomyoma and Uterine Sarcoma using Magnetic Resonance Images: A Literature Review.2019
- Author(s)
  Suzuki A, Aoki M, Miyagawa C, Murakami K, Takaya H, Kotani Y, Nakai H, Matsumura N
- Journal Title
  
  Healthcare (Basel)
  
  Volume: 7 Issue: 4 Pages: 158-158
- DOI
  10.3390/healthcare7040158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09241
[Presentation] PVRL2 upregulation by tumor-associated macrophages confers a regulatory phenotype and is associated with poor prognosis in high-grade serous ovarian cancer2024
- Author(s)
  Kosuke Murakami
- Organizer
  AACR Annual Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0268
[Presentation] The role of myeloid cell-expressed PVRL2 in high-grade serous ovarian cancer2023
- Author(s)
  Kosuke Murakami
- Organizer
  AACR Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0268
[Presentation] The immune profile of ovarian clear cell carcinoma is different from that of high-grade serous carcinoma, with high expression of poliovirus receptor on tumor cells2022
- Author(s)
  Kosuke Murakami
- Organizer
  第74回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-22K16868
[Presentation] 近交系卵巣明細胞癌マウスモデルの樹立と腫瘍免疫の解析2021
- Author(s)
  村上幸祐
- Organizer
  第63回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K18684
[Presentation] Establishment of an inbred mouse model of ovarian clear cell carcinoma and analysis of tumor immunity2021
- Author(s)
  Kosuke Murakami、Chiho Miyagawa、Noriomi Matsumura
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K18684
[Presentation] 近交系卵巣明細胞癌マウスモデルの樹立と腫瘍免疫の解析2021
- Author(s)
  村上幸祐、宮川知保、加藤茂樹、高村史記、宮澤正顯、松村謙臣
- Organizer
  第63回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K18684
[Presentation] SPIO method for the diagnosis of pelvic lymph node metastasis2019
- Author(s)
  村上幸祐
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09241
[Presentation] SPIO method for the diagnosis of pelvic lymph node metastasis2019
- Author(s)
  Murakami Kosuke, Suzuki Ayako, Ohsuga Takuma, Kai Sayaka, Fujishima Risa, Aoki Masato, Yo Yoshie, Takaya Hisamitsu, Kotani Yasushi, Nakai Hidekatsu, Tsuji Isao, Matsumura Noriomi
- Organizer
  第71回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18K09241
[Presentation] SPIO-MRIと鉄染色は、子宮頸癌・体癌のセンチネルリンパ節同定およびリンパ節転移診断に有用である2019
- Author(s)
  村上幸祐, 鈴木彩子, 佐藤華子, 城玲央奈, 大須賀拓真, 甲斐冴, 藤島理沙, 青木稚人, 葉宜慧, 貫戸明子, 高矢寿光, 小谷泰史, 中井英勝, 辻勲, 松村謙臣
- Organizer
  第61回婦人科腫瘍学会
- Data Source
  KAKENHI-PROJECT-18K09241
[Presentation] SPIO METHOD FOR THE DIAGNOSIS OF PELVIC LYMPH NODE METASTASIS2018
- Author(s)
  Kosuke Murakami
- Organizer
  17th Biennial Meeting of the International Gynecologic Cancer Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09241

1. Matsumura Noriomi (20452336)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. SUZUKI Ayako (90378696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 佐藤隆夫 (70162443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 柏木伸夫 (30752745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 高矢寿光 (60734689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 宮澤正顯 (60167757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 貫戸明子 (60550811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. BABA Tsukasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
9. HAMANISHI Jyunzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 万代昌紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
11. 村上隆介

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
12. BROWN John

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 坂井和子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 西尾和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 中井英勝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murakami Kosuke 村上 幸祐

Research Projects

Research Products

Co-Researchers

卵巣明細胞がんのVEGF経路がもたらす腫瘍免疫微小環境の変化と新規治療の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring immune checkpoint pathways as novel therapeutic targets in ovarian cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Probing intratumor heterogeneity and elucidating developmental mechanisms based on cancer-associated genetic mutations in ovarian endometrial carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

卵巣明細胞がんの腫瘍免疫機構の解明と新たな免疫療法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the mechanism of development and preventive method for endometriosis-associated ovarian cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of inbred murine model of ovarian clear cell carcinoma and analysis of host immune responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of diagnosis of lymph node metastasis in uterine cancer by superparamagnetic iron oxide

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Uterine angioleiomyoma with disseminated intravascular coagulation: a case report2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tubulovillous adenoma with high-grade dysplasia of the vulva harboring high tumor mutational burden and cancer-associated mutations: a case report2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] B7-H3 Suppresses Antitumor Immunity via the CCL2-CCR2-M2 Macrophage Axis and Contributes to Ovarian Cancer Progression2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamics2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ovarian teratoid carcinosarcoma with a PIK3CA mutation: a case report and review of the literature.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combination of gene set signatures correlates with response to nivolumab in platinum-resistant ovarian cancer2021

Author(s)

Journal Title

DOI

Murakami Kosuke 村上幸祐