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Takaya Hisamitsu  高矢 寿光

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TAKAYA Hisamitsu  高矢 寿光

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Researcher Number 60734689
Other IDs
Affiliation (Current) 2025: 近畿大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2025: 近畿大学, 医学部, 講師
2020 – 2023: 近畿大学, 医学部, 講師
2017 – 2019: 近畿大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Except Principal Investigator
Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56040:Obstetrics and gynecology-related
Keywords
Principal Investigator
卵巣癌 / HRD / がんゲノム / シングルセル解析 / 卵巣がん / バイオマーカー / BRCA1 / 化学療法 / 相同組換修復 / ゲノム / 癌ゲノム / 腫瘍内不均一性 … More
Except Principal Investigator
… More 卵巣癌 / 卵巣明細胞癌 / PIK3CA変異 / 遺伝子変異解析 / 内膜症関連卵巣癌 / 遺伝子変異 / 子宮内膜症 / 化学療法感受性 / 機能ゲノミクス解析 / 相同組み替え修復 / オミックス解析 / ゲノム解析 / バイオマーカー / 免疫療法 / ゲノム / DNA修復機構 / 幹細胞 / 腫瘍免疫 / 腫瘍内不均一性 Less
  • Research Projects

    (6 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (10 People)
  •  子宮体がんに対する免疫チェックポイント阻害剤の効果のマウスモデルにおける検証Principal Investigator

    • Principal Investigator
      高矢 寿光
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Kindai University
  •  卵巣高異型度漿液性癌のシングルセルHRDの解析と腫瘍内不均一性の解明Principal Investigator

    • Principal Investigator
      高矢 寿光
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Kindai University
  •  Investigation of the mechanism of development and preventive method for endometriosis-associated ovarian cancer

    • Principal Investigator
      Matsumura Noriomi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Kindai University
  •  The exploration of new biomarker for chemo-sensitivity of ovarian cancer based on cancer genomePrincipal Investigator

    • Principal Investigator
      Takaya Hisamitsu
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Kindai University
  •  Development of new treatment for ovarian cancer based on intratumor heterogeneity

    • Principal Investigator
      Matsumura Noriomi
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Kindai University
  •  The establishment of new method of screening with liquid biopsy for ovarian cancerPrincipal Investigator

    • Principal Investigator
      TAKAYA Hisamitsu
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kindai University

All 2024 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Utility of Homologous Recombination Deficiency Biomarkers Across Cancer Types2022

    • Author(s)
      Takamatsu Shiro、Brown J.B.、Yamaguchi Ken、Hamanishi Junzo、Yamanoi Koji、Takaya Hisamitsu、Kaneyasu Tomoko、Mori Seiichi、Mandai Masaki、Matsumura Noriomi
    • Journal Title

      JCO Precision Oncology

      Volume: - Issue: 6

    • DOI

      10.1200/po.22.00085

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09541, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-21H02793
  • [Journal Article] Ovarian teratoid carcinosarcoma with a PIK3CA mutation: a case report and review of the literature.2022

    • Author(s)
      Masato Aoki, Hisamitsu Takaya, Tomoyuki Otani, Hidekatsu Nakai, Kosuke Murakami, Noriomi Matsumura.
    • Journal Title

      Int Cancer Conf J.

      Volume: 11 Issue: 4 Pages: 231-237

    • DOI

      10.1007/s13691-022-00571-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09630, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
  • [Journal Article] Quality of life after laparoscopic hysterectomy versus abdominal hysterectomy2021

    • Author(s)
      Kotani Yasushi、Murakami Kosuke、Fujishima Risa、Kanto Akiko、Takaya Hisamitsu、Shimaoka Masao、Nakai Hidekatsu、Matsumura Noriomi
    • Journal Title

      BMC Women's Health

      Volume: 21 Issue: 1 Pages: 219-219

    • DOI

      10.1186/s12905-021-01382-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Journal Article] Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma2021

    • Author(s)
      Murakami Kosuke、Kanto Akiko、Sakai Kazuko、Miyagawa Chiho、Takaya Hisamitsu、Nakai Hidekatsu、Kotani Yasushi、Nishio Kazuto、Matsumura Noriomi
    • Journal Title

      Modern Pathology

      Volume: 34 Issue: 11 Pages: 2071-2079

    • DOI

      10.1038/s41379-021-00861-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
  • [Journal Article] A Novel Malignant Peritoneal Mesothelioma with STRN Exon 2 and ALK Exon 20: A Case Report and Literature Review.2021

    • Author(s)
      Miyagawa C, Takaya H, Sakai K, Nishio K, Konishi M, Minamiguchi S, Shimada T, Matsumura N.
    • Journal Title

      Oncologist

      Volume: - Issue: 5 Pages: 356-361

    • DOI

      10.1002/onco.13714

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-18H02947
  • [Journal Article] Measures for safe laparoscopic sacrocolpopexy: Preoperative contrast-enhanced computed tomography and perioperative ultrasonography2021

    • Author(s)
      Kotani Yasushi、Murakami Kosuke、Kanto Akiko、Takaya Hisamitsu、Nakai Hidekatsu、Matsumura Noriomi
    • Journal Title

      Gynecology and Minimally Invasive Therapy

      Volume: 10 Issue: 2 Pages: 114-114

    • DOI

      10.4103/gmit.gmit_1_20

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Journal Article] Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma2020

    • Author(s)
      Takaya Hisamitsu、Nakai Hidekatsu、Takamatsu Shiro、Mandai Masaki、Matsumura Noriomi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 2757-2757

    • DOI

      10.1038/s41598-020-59671-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K18713, KAKENHI-PROJECT-17H01587, KAKENHI-PROJECT-18H02947
  • [Journal Article] Endometriosis-associated ovarian cancer occurs early during follow-up of endometrial cysts.2020

    • Author(s)
      Murakami K, Kotani Y, Shiro R, Takaya H, Nakai H, Matsumura N
    • Journal Title

      International journal of clinical oncology

      Volume: 25 Issue: 1 Pages: 51-58

    • DOI

      10.1007/s10147-019-01536-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Journal Article] Superparamagnetic iron oxide as a tracer for sentinel lymph node detection in uterine cancer: a pilot study.2020

    • Author(s)
      Murakami K, Kotani Y, Suzuki A, Takaya H, Nakai H, Matsuki M, Sato T, Mandai M, Matsumura N.
    • Journal Title

      Sci Rep

      Volume: 10 Issue: 1 Pages: 7945-7945

    • DOI

      10.1038/s41598-020-64926-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-18K09241
  • [Journal Article] Clinical Determinants Affecting Indications for Surgery and Chemotherapy in Recurrent Ovarian Granulosa Cell Tumor2019

    • Author(s)
      Nakai Hidekatsu、Koike Eiji、Murakami Kosuke、Takaya Hisamitsu、Kotani Yasushi、Nakai Rika、Suzuki Ayako、Aoki Masato、Matsumura Noriomi、Mandai Masaki
    • Journal Title

      Healthcare

      Volume: 7 Issue: 4 Pages: 145-145

    • DOI

      10.3390/healthcare7040145

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Journal Article] Intratumor heterogeneity and homologous recombination deficiency of high-grade serous ovarian cancer are associated with prognosis and molecular subtype and change in treatment course.2019

    • Author(s)
      Takaya H, Nakai H, Sakai K, Nishio K, Murakami K, Mandai M, *Matsumura N.
    • Journal Title

      Gynecol Oncol.

      Volume: 156 Issue: 2 Pages: 415-422

    • DOI

      10.1016/j.ygyno.2019.11.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-18H02947
  • [Journal Article] Malignant psoas syndrome associated with gynecological malignancy: Three case reports and a review of the literature.2018

    • Author(s)
      Takamatsu S, Murakami K, Takaya H, Tobiume T, Nakai H, Suzuki A, Mandai M, Matsumura N
    • Journal Title

      Mol Clin Oncol

      Volume: 9 Pages: 82-86

    • DOI

      10.3892/mco.2018.1635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Journal Article] Efficacy of weekly administration of paclitaxel and carboplatin for advanced ovarian cancer patients with poor performance status.2018

    • Author(s)
      Takaya H, Nakai H, Murakami K, Tobiume T, Suzuki A, Mandai M, Matsumura N
    • Journal Title

      Int J Clin Oncol

      Volume: 23 Issue: 4 Pages: 698-706

    • DOI

      10.1007/s10147-018-1264-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Presentation] Changes in HRD status during treatment for ovarian high-grade serous carcinoma2024

    • Author(s)
      Noriomi Matsumura, Hisamitsu Takaya, Shiro Takamatsu
    • Organizer
      SGO Annual Meeting on Women's Cancer
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09606
  • [Presentation] DNA repair status and copy number alteration of high-grade serous ovarian cancer change in a treatment course2021

    • Author(s)
      高矢寿光、中井英勝、坂井和子、西尾和人、松村謙臣
    • Organizer
      第18回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K18713
  • [Presentation] Homologous recombination deficiency and copy number alteration varies in a course of treatment in high grade serous ovarian cancer2020

    • Author(s)
      Hisamitsu Takaya, Hidekatsu Nakai, Ayako Suzuki, Yasushi Kotani, Kosuke Murakami, Tamaki Yahata, Masato Aoki, Chiho Miyagawa, Reona Shiro, Mamiko Ohta, Sayaka Kai, Noriomi Matsumura
    • Organizer
      第72回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K18713
  • [Presentation] Intratumor heterogeneity and homologous recombination deficiency of high grade serous ovarian cancer are associated with prognosis and molecular subtypes and change in treatment course2019

    • Author(s)
      Hisamitsu Takaya, Hidekatsu Nakai, Kosuke Murakami, Noriomi Matsumura
    • Organizer
      Advances in Ovarian Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18713
  • [Presentation] 卵巣高異型度漿液性癌のゲノム解析によるDNA修復機構の破綻および腫瘍内不均一性の解明2019

    • Author(s)
      高矢寿光, 中井英勝, 坂井和子, 西尾和人, 松村謙臣
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19K18713
  • [Presentation] Clonality and loss of heterogeneity are associated with prognosis amd subtypes in high grade serous ovarian cancer.2018

    • Author(s)
      Hisamitsu Takaya, Hidekatsu Nakai, Kazuko Sakai, Kazuto Nishio, Noriomi Matsumura
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Presentation] Oligoclonality following chemotherapy in high grade serous ovarian cancer.2018

    • Author(s)
      Hisamitsu Takaya, Hidekatsu Nakai, Takako Tobiume, Ayako Suzuki, Kosuke Murakami, Shiro Takamatsu, Masao Shimaoka, Yoshie Yo, Masato Aoki, Risa Fujishima, Hanako Sato, Noriomi Matsumura
    • Organizer
      第70回日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-18H02947
  • [Presentation] 卵巣高悪性度漿液性腺癌では化学療法後にクローン数が減少する2018

    • Author(s)
      高矢寿光,坂井和子,西尾和人,松村謙臣
    • Organizer
      第22回 日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K16873
  • [Presentation] Oligoclonality following chemotherapy in high grade serous ovarian cancer2018

    • Author(s)
      高矢寿光,中井英勝,飛梅孝子,鈴木彩子,村上幸祐,高松士朗,島岡昌生,葉宜慧,青木稚人,藤島理沙,佐藤華子,松村謙臣
    • Organizer
      第70回 日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-17K16873
  • [Presentation] Clonality and loss of heterozygosity are associated with prognosis and subtypes in high grade serous ovarian cancer2018

    • Author(s)
      高矢寿光,中井英勝,坂井和子,西尾和人,松村謙臣
    • Organizer
      第77回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K16873
  • [Presentation] Chemotherapy induced oligoclonality and high clonality related with recurrence in high grade serous ovarian cancer2018

    • Author(s)
      Hisamitsu Takaya, Hidekatsu Nakai, Kosuke Murakami, Yasushi Kotani, Ayako Suzuki, Masaki Mandai, Noriomi Matsumura
    • Organizer
      17th Biennial Meeting of the International Gynecologic Cancer Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16873
  • [Presentation] 卵巣高悪性度漿液性腺癌では化学療法後にクローン数が減少する2017

    • Author(s)
      高矢 寿光、中井 英勝、坂井 和子、西尾 和人、松村 謙臣
    • Organizer
      第76回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K16873
  • 1.  Matsumura Noriomi (20452336)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 18 results
  • 2.  宮澤 正顯 (60167757)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  西尾 和人 (10208134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  坂井 和子 (20580559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  佐藤 隆夫 (70162443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  万代 昌紀 (80283597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  村上 隆介 (40782363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 8.  村上 幸祐 (60734671)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  HAMANISHI Jyunzo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  中井 英勝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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