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Ohno Satoshi  大野 聡

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大野 聡  オオノ サトシ

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Researcher Number 60755734
Other IDs
Affiliation (Current) 2025: 東京科学大学, 総合研究院, 講師
Affiliation (based on the past Project Information) *help 2024: 東京医科歯科大学, M&Dデータ科学センター, 講師
2022: 東京医科歯科大学, M&Dデータ科学センター, 講師
2021: 東京大学, 大学院理学系研究科(理学部), 助教
2019: 東京大学, 大学院理学系研究科(理学部), 助教
2017 – 2018: 東京大学, 大学院理学系研究科(理学部), 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 62010:Life, health and medical informatics-related / Basic Section 27040:Biofunction and bioprocess engineering-related / Biofunction/Bioprocess
Keywords
Principal Investigator
臓器連関 / システム生物学 / 代謝工学 / メタボローム分析 / 代謝フラックス解析 / シングルセル解析 / 代謝 / 深層学習 / 反応速度論 / 生体生命情報学 … More / 生物・生体工学 / 代謝光学 / 哺乳類 / プロテオーム分析 Less
  • Research Projects

    (3 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (3 People)
  •  Deep learning of human whole body metabolism and organ-organ interactionsPrincipal Investigator

    • Principal Investigator
      大野 聡
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 62010:Life, health and medical informatics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Inter-organ metabolic flux analysis for glucose-administrated micePrincipal Investigator

    • Principal Investigator
      大野 聡
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      Tokyo Medical and Dental University
      The University of Tokyo
  •  Metabolic flux analysis for the liver of mice administered with glucosePrincipal Investigator

    • Principal Investigator
      Ohno Satoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      The University of Tokyo

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Trans-omics analysis of insulin action reveals a cell growth subnetwork which co-regulates anabolic processes2022

    • Author(s)
      Terakawa Akira、Hu Yanhui、Kokaji Toshiya、Yugi Katsuyuki、Morita Keigo、Ohno Satoshi、Pan Yifei、Bai Yunfan、Parkhitko Andrey A.、Ni Xiaochun、Asara John M.、Bulyk Martha L.、Perrimon Norbert、Kuroda Shinya
    • Journal Title

      iScience

      Volume: 25 Issue: 5 Pages: 104231-104231

    • DOI

      10.1016/j.isci.2022.104231

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-18H03979, KAKENHI-PROJECT-21H04759, KAKENHI-PLANNED-18H05431, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300
  • [Journal Article] In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states.2022

    • Author(s)
      Kokaji T, Eto M, Hatano A, Yugi K, Morita K, Ohno S, Fujii M, Hironaka KI, Ito Y, Egami R, Uematsu S, Terakawa A, Pan Y, Maehara H, Li D, Bai Y, Tsuchiya T, Ozaki H, Inoue H, Kubota H, Suzuki Y, Hirayama A, Soga T, Kuroda S.
    • Journal Title

      Sci Rep

      Volume: 12 Issue: 1 Pages: 13719-13719

    • DOI

      10.1038/s41598-022-17964-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-20K19915, KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-20H03237, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-18H05431, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300
  • [Journal Article] Quantitative metabolic fluxes regulated by trans-omic networks2022

    • Author(s)
      Ohno Satoshi、Uematsu Saori、Kuroda Shinya
    • Journal Title

      Biochemical Journal

      Volume: 479 Issue: 6 Pages: 787-804

    • DOI

      10.1042/bcj20210596

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19J22134, KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-18H03979, KAKENHI-PROJECT-21H04759, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300
  • [Journal Article] Multi-omics-based label-free metabolic flux inference reveals obesity-associated dysregulatory mechanisms in liver glucose metabolism2022

    • Author(s)
      Uematsu Saori、Ohno Satoshi、Tanaka Kaori Y.、Hatano Atsushi、Kokaji Toshiya、Ito Yuki、Kubota Hiroyuki、Hironaka Ken-ichi、Suzuki Yutaka、Matsumoto Masaki、Nakayama Keiichi I.、Hirayama Akiyoshi、Soga Tomoyoshi、Kuroda Shinya
    • Journal Title

      iScience

      Volume: 25 Issue: 2 Pages: 103787-103787

    • DOI

      10.1016/j.isci.2022.103787

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06577, KAKENHI-ORGANIZER-17H06299, KAKENHI-PROJECT-18H05215, KAKENHI-PLANNED-20H05930, KAKENHI-PROJECT-19J22134, KAKENHI-PROJECT-20K21386, KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-20H03237, KAKENHI-PROJECT-18H03979, KAKENHI-PROJECT-21H04759, KAKENHI-PLANNED-17H06300
  • [Journal Article] Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin2020

    • Author(s)
      Quek Lake-Ee、Krycer James R.、Ohno Satoshi、Yugi Katsuyuki、Fazakerley Daniel J.、Scalzo Richard、Elkington Sarah D.、Dai Ziwei、Hirayama Akiyoshi、Ikeda Satsuki、Shoji Futaba、Suzuki Kumi、Locasale Jason W.、Soga Tomoyoshi、James David E.、Kuroda Shinya
    • Journal Title

      iScience

      Volume: 23 Issue: 2 Pages: 100855-100855

    • DOI

      10.1016/j.isci.2020.100855

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14864, KAKENHI-PROJECT-15H05582
  • [Journal Article] Rate-oriented trans-omics: integration of multiple omic data on the basis of reaction kinetics2019

    • Author(s)
      Yugi Katsuyuki、Ohno Satoshi、Krycer James R.、James David E.、Kuroda Shinya
    • Journal Title

      Current Opinion in Systems Biology

      Volume: 15 Pages: 109-120

    • DOI

      10.1016/j.coisb.2019.04.005

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14864, KAKENHI-PLANNED-18H05431, KAKENHI-PROJECT-15H05582
  • [Journal Article] Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism2017

    • Author(s)
      James R. Krycer, Satoshi Ohnoら全21名
    • Journal Title

      Cell Reports

      Volume: 21 Issue: 12 Pages: 3536-3547

    • DOI

      10.1016/j.celrep.2017.11.085

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14864, KAKENHI-PROJECT-15H05582, KAKENHI-PROJECT-15K21364, KAKENHI-PLANNED-17H06300
  • [Presentation] 少数の酵素に対するインスリン依存性リン酸化とアロステリック制御による脂肪細胞の糖代謝制御2022

    • Author(s)
      大野聡、黒田真也
    • Organizer
      第45回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K14467
  • [Presentation] 脂肪細胞におけるインスリン依存性糖代謝の速度論的トランスオミクス解析2021

    • Author(s)
      大野聡
    • Organizer
      質量インフォマティクス研究会 2021年ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K14467
  • [Presentation] Omics-based label-free metabolic flux inference reveals dysregulation of glucose metabolism in liver associated with obesity2021

    • Author(s)
      植松沙織、大野聡、黒田真也
    • Organizer
      日本バイオインフォマティクス学会
    • Data Source
      KAKENHI-PROJECT-21K14467
  • [Presentation] 脂肪細胞におけるインスリン依存性糖代謝の速度論的トランスオミクス解析2021

    • Author(s)
      大野聡、黒田真也
    • Organizer
      日本プロテオーム学会 2021年大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K14467
  • [Presentation] Regulation of metabolic fluxes in adipocytes with insulin2019

    • Author(s)
      Satoshi Ohno, Akiyoshi Hirayama, Tomoyoshi Soga, David E. James, Shinya Kuroda
    • Organizer
      第13回メタボロームシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K14864
  • [Presentation] Metabolic flux changes over time and the regulatory mechanisms in insulin-stimulated adipocytes2019

    • Author(s)
      Satoshi Ohno, Lake-Ee Quek, James R. Krycer, Katsuyuki Yugi, Akiyoshi Hirayama, Tomoyoshi Soga, David E. James, Shinya Kuroda
    • Organizer
      20th International Conference On Systems Biology (ICSB2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14864
  • [Presentation] インスリン刺激下の脂肪細胞の代謝フラックスおよびその調節の数理解析2019

    • Author(s)
      大野 聡
    • Organizer
      第4回生活習慣病とがんの代謝栄養メカニズム研究会
    • Data Source
      KAKENHI-PROJECT-17K14864
  • [Presentation] 13C-based dynamic metabolic flux analysis in insulin-stimulated adipocyte cell lines and systematic evaluation of regulation on the metabolism2018

    • Author(s)
      Satoshi Ohno, Lake-Ee Quek, James R. Krycer, Katsuyuki Yugi, Akiyoshi Hirayama, Tomoyoshi Soga, David E. James, Shinya Kuroda
    • Organizer
      Metabolic Engineering 12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14864
  • [Presentation] 代謝システムの理解と応用に向けた数理解析2017

    • Author(s)
      大野 聡
    • Organizer
      日本生物工学会【研究部会】バイオインフォマティクス相談部会 第一回勉強会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K14864
  • 1.  清水 秀幸 (70826263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  井上 啓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  久保田 浩行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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