SHIMA Fumiaki 島史明

Researcher Number	60756659
Affiliation (based on the past Project Information) *help	2015: 大阪大学, 生命機能研究科, 特任助教 2015: 大阪大学, 大学院生命機能研究科, 特任助教
Review Section/Research Field	Except Principal Investigator Polymer chemistry
Keywords	Except Principal Investigator 交互積層法 / 高分子薄膜・表面 / 高分子化学

Creation of Functional Materials Using Polymer Self Assembly and Biomedical Application
- Principal Investigator
  
  AKASHI Mitsuru
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Polymer chemistry
- Research Institution
  Osaka University

All 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid)2015
- Author(s)
  Fumiaki Shima, Takami Akagi, Manami Shudo, Eiko Mochizuki, Tetsuya Tsuda, Susumu Kuwabata, Mitsuru Akashi
- Journal Title
  
  Polym. J.
  
  Volume: 47 Issue: 9 Pages: 631-638
- DOI
  10.1038/pj.2015.40
- NAID
  40020583089
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23225004
[Journal Article] “Effect of hydrophobic side chains in the induction of immune responses by nanoparticle adjuvants consisting of amphiphilic poly(γ-glutamic acid)”2015
- Author(s)
  Fumiaki Shima, Takami Akagi, Mitsuru Akashi,
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23225004
[Journal Article] The hydrophobic effect of nanoparticles composed of amphiphilic poly(γ-glutamic acid) on the degradability of the encapsulated proteins2014
- Author(s)
  Fumiaki Shima, Takami Akagi, Mitsuru Akashi
- Journal Title
  
  Biomaterials Science
  
  Volume: 2 Issue: 10 Pages: 1419-1425
- DOI
  10.1039/c4bm00140k
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J00745, KAKENHI-PROJECT-23225004
[Journal Article] The role of hydrophobicity in the disruption of erythrocyte membrane by nanoparticles composed of hydrophobically modified poly (γ-glutamic acid)2014
- Author(s)
  Fumiaki Shima, Takami Akagi, Mitsuru Akashi
- Journal Title
  
  Journal of Biomaterials Science, Polymer Edition
  
  Volume: 25 Issue: 2 Pages: 203-210
- DOI
  10.1080/09205063.2013.848328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00745, KAKENHI-PROJECT-23225004
[Journal Article] Preparation of functional vesicles composed of amphiphilic poly(γ-glutamic acid) by hydrophobic interaction2014
- Author(s)
  Fumiaki Shima, Bjoern Schulte, Helmut Keul, Martin Moeller, Mitsuru Akashi
- Journal Title
  
  Polymer Journal
  
  Volume: 46 Issue: 3 Pages: 184-188
- DOI
  10.1038/pj.2013.74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00745, KAKENHI-PROJECT-23225004
[Journal Article] Synthesis and preparation of nanoparticles composed of amphiphilic poly(γ-glutamic acid) with different hydrophobic side chains and their potential of membrane disruptive activity2014
- Author(s)
  Fumiaki Shima, Takami Akagi, Mitsuru Akashi
- Journal Title
  
  Colloid Polymer Science
  
  Volume: 292 Issue: 10 Pages: 2663-2671
- DOI
  10.1007/s00396-014-3303-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J00745, KAKENHI-PROJECT-23225004
[Journal Article] Simple Observation of the Interaction between Nanoparticles and Cells by Scanning Electron Microscopy Employing Ionic Liquid2013
- Author(s)
  Fumiaki Shima, Koshi Kawakami, Takami Akagi, Eiko Mochizuki, Tetsuya Tsuda, Susumu Kuwabata, Mitsuru Akashi
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: 86 Issue: 1 Pages: 153-158
- DOI
  10.1246/bcsj.20120227
- NAID
  130004153132
- ISSN
  0009-2673, 1348-0634
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23225004, KAKENHI-PUBLICLY-23107518
[Journal Article] Size effect of amphiphilic poly(γ-glutamic acid) nanoparticles on cellular uptake and maturation of dendritic cells in vivo2013
- Author(s)
  Fumiaki Shima, Tomofumi Uto, Takami Akagi, Masanori Baba, Mitsuru Akashi
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 9 Issue: 11 Pages: 8894-8901
- DOI
  10.1016/j.actbio.2013.06.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00745, KAKENHI-PROJECT-23225004
[Journal Article] Synergistic stimulation of antigen presenting cells via TLR by combining CpG ODN and poly(γ-glutamic acid)-based nanoparticles as vaccine adjuvants2013
- Author(s)
  Fumiaki Shima, Tomofumi Uto, Takami Akagi, Mitsuru Akashi
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 24 Issue: 6 Pages: 926-933
- DOI
  10.1021/bc300611b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00745, KAKENHI-PROJECT-23225004
[Journal Article] Manipulating the antigen-specific immune responses by the hydrophobicity of nanoparticles composed of amphiphilic poly(γ-gluta mic acid)2013
- Author(s)
  Fumiaki Shima, Tomofumi Uto, Takami Akagi, Mitsuru Akashi
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 37 Pages: 9709-9716
- DOI
  10.1016/j.biomaterials.2013.08.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00745, KAKENHI-PROJECT-23225004
[Presentation] Layer-by-Layer法による栄養血管を含む動脈壁モデルの構築と再生医療への応用2016
- Author(s)
  島　史明、松崎典弥、明石　満
- Organizer
  日本化学会第96春季年会(2016)
- Place of Presentation
  同志社大学　京田辺キャンパス（京都府）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] Manipulation of immune responses by the hydrophobicity of nanoparticle adjuvants composed of amphiphilic poly(γ-glutamic acid)2015
- Author(s)
  Fumiaki Shima, Takami Akagi, Mitsuru Akashi
- Organizer
  Pacifichem2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 両親媒性ポリアミノ酸ナノ粒子による免疫応答制御と疎水基の効果2015
- Author(s)
  島　史明、赤木隆美、明石　満
- Organizer
  第31回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 免疫応答を制御可能な両親媒性ポリ(γ-グルタミン酸) ナノ粒子アジュバントの調製と疎水化効果2013
- Author(s)
  島史明・宇都倫史・赤木隆美・*明石満
- Organizer
  第62回高分子討論会
- Place of Presentation
  金沢（金沢大学角間キャンパス）
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 顕微鏡観察による生分解性ナノ粒子の細胞内取り込み過程の視覚的評価2012
- Author(s)
  首藤真奈見・島史明・赤木隆美・桑畑進・明石満
- Organizer
  第61回　高分子学会討論会
- Place of Presentation
  名古屋工業大学
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] イオン液体を用いたSEM観察による細胞のナノ粒子取り込み挙動の評価2012
- Author(s)
  首藤真奈見・島　史明・赤木隆美・桑畑　進・明石満
- Organizer
  第61回　高分子学会年次大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] In vitro of Drug Permeability Using Normal and Inflammatory Three-Dimensional Blood Vessel Models Fabricated by Hierarchical Cell Manipulation2012
- Author(s)
  Paninee Chetprayoon ・Koji Kadowaki ・Michiya Matsusaki・Takami Akagi・Fumiaki Shima・Mitsuru Akashi
- Organizer
  第61回　高分子学会討論会
- Place of Presentation
  名古屋工業大学
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 正常および炎症ヒト血管三次元モデルによるドラッグキャリアの血管透過性評価への応用2012
- Author(s)
  チェトプラユーン　パーニニー・門脇功治・松﨑典弥・赤木隆美・島史明・明石満
- Organizer
  第58回　高分子研究発表会
- Place of Presentation
  兵庫県民会館
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 両親媒性ポリ (g-グルタミン酸) ナノ粒子アジュバントの疎水性の違いによる免疫応答制御
- Author(s)
  島史明・赤木隆美・明石満
- Organizer
  日本化学会95春季年会
- Place of Presentation
  日本大学船橋キャンパス
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 両親媒性ポリ(γ-グルタミン酸)ナノ粒子の疎水性とアジュバント機能
- Author(s)
  島史明・赤木隆美・明石満
- Organizer
  第63回　高分子討論会
- Place of Presentation
  長崎大学文教キャンパス
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 種々の異なる疎水基を有する両親媒性ポリ(γ-グルタミン酸) ナノ粒子の調製とワクチンアジュバントへの応用
- Author(s)
  島史明・赤木隆美・明石満
- Organizer
  第63回　高分子学会年次大会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2014-05-28 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-23225004
[Presentation] 両親媒性ポリ(γ-グルタミン酸) ナノ粒子を構成する疎水基及び剤形による免疫誘導制御
- Author(s)
  島史明，赤木隆美，明石満
- Organizer
  第36回　日本バイオマテリアル学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2014-11-17 – 2014-11-18
- Data Source
  KAKENHI-PROJECT-23225004

1. AKASHI Mitsuru (20145460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. KIDA Toshiyuki (20234297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MATSUSAKI Michiya (00419467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. AKAGI Takami (00527236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. AJIRO Hiroharu (50437331)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TABATA Masashi (60207214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MURAOKA Masahiro (80411411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. WAKU Tomonori (30548699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HIRANO Hiroshi (10416349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SAWA Yoshiki (00243220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HASHIMOTO Koji (00110784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMA Fumiaki 島 史明

Research Projects

Research Products

Co-Researchers

Creation of Functional Materials Using Polymer Self Assembly and Biomedical Application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid)2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] “Effect of hydrophobic side chains in the induction of immune responses by nanoparticle adjuvants consisting of amphiphilic poly(γ-glutamic acid)”2015

Author(s)

Journal Title

Data Source

[Journal Article] The hydrophobic effect of nanoparticles composed of amphiphilic poly(γ-glutamic acid) on the degradability of the encapsulated proteins2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The role of hydrophobicity in the disruption of erythrocyte membrane by nanoparticles composed of hydrophobically modified poly (γ-glutamic acid)2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preparation of functional vesicles composed of amphiphilic poly(γ-glutamic acid) by hydrophobic interaction2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and preparation of nanoparticles composed of amphiphilic poly(γ-glutamic acid) with different hydrophobic side chains and their potential of membrane disruptive activity2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simple Observation of the Interaction between Nanoparticles and Cells by Scanning Electron Microscopy Employing Ionic Liquid2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Size effect of amphiphilic poly(γ-glutamic acid) nanoparticles on cellular uptake and maturation of dendritic cells in vivo2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synergistic stimulation of antigen presenting cells via TLR by combining CpG ODN and poly(γ-glutamic acid)-based nanoparticles as vaccine adjuvants2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Manipulating the antigen-specific immune responses by the hydrophobicity of nanoparticles composed of amphiphilic poly(γ-gluta mic acid)2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Layer-by-Layer法による栄養血管を含む動脈壁モデルの構築と再生医療への応用2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Manipulation of immune responses by the hydrophobicity of nanoparticle adjuvants composed of amphiphilic poly(γ-glutamic acid)2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 両親媒性ポリアミノ酸ナノ粒子による免疫応答制御と疎水基の効果2015

Author(s)

Organizer

Place of Presentation

Year and Date

SHIMA Fumiaki 島史明