OHIRA Takahito 大平崇人

… Alternative Names

Takahito Ohira 大平崇人

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Researcher Number	60757665
Other IDs
Affiliation (Current)	2025: 鳥取大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 鳥取大学, 医学部, 助教 2018 – 2019: 鳥取大学, 医学(系)研究科(研究院), 助教 2015 – 2016: 鳥取大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Basic Section 57020:Oral pathobiological science-related / General medical chemistry Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator PITX1 / がん抑制遺伝子 / メラノーマ / 薬剤耐性 / がん遺伝子 / テロメレース / 染色体工学 / 口腔扁平上皮がん / BRAF / ChIP-seq … More / 腫瘍生物学 / がん / TERT / 不死化 / ＰＩＴＸ１ / LC/MS/MS / hTERT … More Except Principal Investigator 染色体工学 / 膵がん / TERT / がん抑制遺伝子 Less

Functional analysis of genes that control immortalization of oral cancer using chromosome engineering technology.Principal Investigator
- Principal Investigator
  
  大平崇人
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Tottori University
染色体工学技術と次世代シーケンス解析の融合による膵がんの新規がん抑制経路の同定
- Principal Investigator
  
  坂野悠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tottori University
Identification of a novel drug resistance mechanism in melanoma cellsPrincipal Investigator
- Principal Investigator
  
  OHIRA Takahito
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tottori University
PITX1 inhbits melanoma proliferation by regulation of SOX10 transcriptionPrincipal Investigator
- Principal Investigator
  
  OHIRA Takahito
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tottori University
Studies of the molecular mechanisms in the regulation of telomerase activity and cell immortarization.Principal Investigator
- Principal Investigator
  
  Takahito Ohira
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Tottori University

All 2023 2021 2020 2019 2018 2016

All Journal Article Presentation

[Journal Article] Human artificial chromosome carrying 3p21.3-p22.2 region suppresses hTERT transcription in oral cancer cells.2023
- Author(s)
  Ohira T, Yoshimura K, Kugoh H.
- Journal Title
  
  Chromosome Research
  
  Volume: 24 Issue: 3
- DOI
  10.1007/s10577-023-09734-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16213
[Journal Article] Ohira T, Nakagawa S, Takeshita J, Aburatani H, Kugoh H.2021
- Author(s)
  Ohira T, Nakagawa S, Takeshita J, Aburatani H, Kugoh H.
- Journal Title
  
  Scientific Reports
  
  Volume: 15;11(1):18405. Issue: 1
- DOI
  10.1038/s41598-021-97791-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16213
[Journal Article] A novel Xist RNA-mediated chromosome inactivation model using a mouse artificial chromosome2020
- Author(s)
  Inaoka, D. Sunamura, N. Ohira, T. Nakayama, Y. Kugoh, H.
- Journal Title
  
  Biotechnology letters
  
  Volume: 42 Issue: 5 Pages: 697-705
- DOI
  10.1007/s10529-020-02826-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06183, KAKENHI-PROJECT-19K10086, KAKENHI-PROJECT-17J03813, KAKENHI-PROJECT-18K16030
[Journal Article] Possible Relationship Between <i>MYBL1</i> Alterations and Specific Primary Sites in Adenoid Cystic Carcinoma: A Clinicopathological and Molecular Study of 36 Cases2019
- Author(s)
  Endo Yukari、Kuwamoto Satoshi、Ohira Takahito、Matsushita Michiko、Matsushige Takahiro、Fukuhara Takahiro、Nakamoto Shu、Hayashi Kazuhiko、Kugoh Hiroyuki、Hirooka Yasuaki
- Journal Title
  
  Yonago Acta Medica
  
  Volume: 62 Issue: 1 Pages: 067-076
- DOI
  10.33160/yam.2019.03.010
- NAID
  130007626300
- ISSN
  0513-5710, 1346-8049
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16030
[Journal Article] An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells.2019
- Author(s)
  Ohira T, Miyauchi K, Uno N, Shimizu N, Kazuki Y, Oshimura M, Kugoh H.
- Journal Title
  
  Scientific Reports
  
  Volume: 18 Issue: 1
- DOI
  10.1038/s41598-019-53116-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10086, KAKENHI-PROJECT-18K16030
[Journal Article] PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription.2019
- Author(s)
  Ohira T, Kojima H, Kuroda Y, Aoki S, Inaoka D, Osaki M, Wanibuchi H, Okada F, Oshimura M, Kugoh H.
- Journal Title
  
  Plos one
  
  Volume: 12 Issue: 8 Pages: e0217605-e0217605
- DOI
  10.1371/journal.pone.0217605
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10086, KAKENHI-PROJECT-18K16030, KAKENHI-PROJECT-17K08761
[Presentation] マウス由来の膵がん細胞において3p21.3領域を搭載したヒト人工染色体はmTert発現を抑制する2023
- Author(s)
  坂野　悠、大平崇人、久郷　裕之
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K16213
[Presentation] ヒト人工染色体を応用したhTERT抑制遺伝子のマッピング2023
- Author(s)
  大平崇人、久郷　裕之
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K16213
[Presentation] PITX1はSOX9を介してメラノーマの増殖を抑制する2021
- Author(s)
  大平崇人、久郷　裕之
- Organizer
  第44回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K16213
[Presentation] PITX1 is a novel suppressor of SOX10 and inhibit melanoma growth.2020
- Author(s)
  T. Ohira, H. Kugoh.
- Organizer
  第79回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16030
[Presentation] An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells.2019
- Author(s)
  T. Ohira, K. Miyauchi, N. UNO, N. Shimizu, K. Kazuki, M. Oshimura, H. Kugoh.
- Organizer
  第41回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K16030
[Presentation] X染色体不活化機構解明に向けた人工染色体の活用2018
- Author(s)
  稲岡大悟, 大平崇人,押村光雄, 中山祐二, 久郷裕之
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K16030
[Presentation] miR-19b up-regulates hTERT expression by inhibition of PITX1 in melanoma cells2016
- Author(s)
  T. Ohira, N. Sunamura, D Inaoka, Y Nakayama, M Osaki, F Okada,M. Oshimura, H. Kugoh.
- Organizer
  第13回国際人類遺伝学会
- Place of Presentation
  国立京都国際会館(京都府、京都市)
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06414
[Presentation] PITX1タンパク質はhTERT発現を制御するためにZCCHC10と相互作用する2016
- Author(s)
  T. Ohira, H. Kojima,　Y. Kuroda, D. Inaoka , K. Moriwaki, K. Kasuga, M. Kataoka, T. Inoue, M. Oshimura, H. Kugoh
- Organizer
  第39回　日本分子生物学会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H06414
[Presentation] miR-19b up-regulates hTERT expression by inhibition of PITX1 in melanoma cells2016
- Author(s)
  T. Ohira, N. Sunamura, D Inaoka, Y Nakayama, M Osaki, F Okada,M. Oshimura, H. Kugoh.
- Organizer
  第13回国際人類遺伝学会
- Place of Presentation
  京都国際会議場 (京都府京都市)
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06414
[Presentation] β-catenin controls the expression profiles of KCNQ1OT1/LIT1 long noncoding RNA2016
- Author(s)
  H Kugoh, T Ohira, D Inaoka, M Kataoka, H Tanabe, M. Oshimura, N Sunamura.
- Organizer
  第13回国際人類遺伝学会
- Place of Presentation
  京都国際会議場 (京都府京都市)
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06414

1. 坂野悠 (10974058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 久郷裕之 (40225131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 藤原義之 (40314330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Inaoka Daigo

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. Kuroda Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 中山祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OHIRA Takahito 大平 崇人

Takahito Ohira 大平 崇人

Research Projects

Research Products

Co-Researchers

Functional analysis of genes that control immortalization of oral cancer using chromosome engineering technology.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

染色体工学技術と次世代シーケンス解析の融合による膵がんの新規がん抑制経路の同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of a novel drug resistance mechanism in melanoma cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PITX1 inhbits melanoma proliferation by regulation of SOX10 transcriptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies of the molecular mechanisms in the regulation of telomerase activity and cell immortarization.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Human artificial chromosome carrying 3p21.3-p22.2 region suppresses hTERT transcription in oral cancer cells.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ohira T, Nakagawa S, Takeshita J, Aburatani H, Kugoh H.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel Xist RNA-mediated chromosome inactivation model using a mouse artificial chromosome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possible Relationship Between <i>MYBL1</i> Alterations and Specific Primary Sites in Adenoid Cystic Carcinoma: A Clinicopathological and Molecular Study of 36 Cases2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] マウス由来の膵がん細胞において3p21.3領域を搭載したヒト人工染色体はmTert発現を抑制する2023

Author(s)

Organizer

Data Source

[Presentation] ヒト人工染色体を応用したhTERT抑制遺伝子のマッピング2023

Author(s)

Organizer

Data Source

[Presentation] PITX1はSOX9を介してメラノーマの増殖を抑制する2021

Author(s)

Organizer

Data Source

OHIRA Takahito 大平崇人

Takahito Ohira 大平崇人