Hatano Koji 波多野浩士

Researcher Number	60762234
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 大阪大学, 大学院医学系研究科, 講師 2021: 大阪大学, 医学系研究科, 講師 2020: 大阪大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related Except Principal Investigator Basic Section 56030:Urology-related / Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator 前立腺癌 / 発癌 / 運動 / メタボローム / 生活習慣 / 放射線 / スクリーニング / CRISPR / CRISPR/Cas9 / 放射線治療 … More Except Principal Investigator … More 前立腺癌 / アンドロゲン / 腸内細菌叢 / 腫瘍微小環境 / 多因子間相互作用 / メタボローム解析 / メタゲノム解析 / 腸内細菌 / GWAS / lifestyle / metagenome analysis / short chain fatty acid / metabolome analysis / life style / microbiome / prostate cancer / 放射線感受性 Less

運動と食生活による前立腺癌の増殖制御の解明と革新的ながん予防への展開Principal Investigator
- Principal Investigator
  
  波多野浩士
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  The University of Osaka
機能的スクリーニングに基づく前立腺癌の放射線感受性メカニズムの解明
- Principal Investigator
  
  岡利樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
腫瘍微小環境における多因子間相互作用ネットワーク定量的検出への挑戦
- Principal Investigator
  
  二村圭祐
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Osaka University
腸内細菌叢によるアンドロゲンシグナル経路を介した去勢抵抗性前立腺癌進展機序の解明
- Principal Investigator
  
  藤田和利
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kindai University
生活習慣による代謝物プロファイル変化を介する前立腺癌の増殖制御Principal Investigator
- Principal Investigator
  
  波多野浩士
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
Diagnostic strategy for prostate cancer based on multifaceted analyses of genetic background, life style and gut microbiome
- Principal Investigator
  
  野々村祝夫
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
CRISPR screens identify novel targets that sensitize prostate cancer cells to ionizing radiation.Principal Investigator
- Principal Investigator
  
  Hatano Koji
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Emerging Relationship between the Gut Microbiome and Prostate Cancer2023
- Author(s)
  Matsushita Makoto、Fujita Kazutoshi、Hatano Koji、De Velasco Marco A.、Tsujimura Akira、Uemura Hirotsugu、Nonomura Norio
- Journal Title
  
  The World Journal of Men's Health
  
  Volume: 41 Issue: 4 Pages: 759-759
- DOI
  10.5534/wjmh.220202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08791, KAKENHI-PROJECT-21K09421, KAKENHI-PROJECT-23K24471
[Journal Article] The Gut-Prostate Axis: A New Perspective of Prostate Cancer Biology through the Gut Microbiome2023
- Author(s)
  Fujita Kazutoshi、Matsushita Makoto、De Velasco Marco A.、Hatano Koji、Minami Takafumi、Nonomura Norio、Uemura Hirotsugu
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 5 Pages: 1375-1375
- DOI
  10.3390/cancers15051375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09421, KAKENHI-PROJECT-23K24471
[Journal Article] Prognostic significance of serum fucosylated pro-haptoglobin in advanced renal cell carcinoma patients treated with immune checkpoint inhibitors2023
- Author(s)
  Kato Taigo、Morishita Koichi、Tomiyama Eisuke、Hayashibara Ayumu、Ishizuya Yu、Yamamoto Yoshiyuki、Hatano Koji、Kawashima Atsunari、Fukuhara Shinichiro、Nonomura Norio、Miyoshi Eiji、Fujita Kazutoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 17239-17239
- DOI
  10.1038/s41598-023-42739-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24228, KAKENHI-PROJECT-23K24471
[Journal Article] The presence of lymph node metastases and time to castration resistance predict the therapeutic effect of enzalutamide for castration-resistant prostate cancer.2023
- Author(s)
  Oka T, Hatano K, Okuda Y, Yamamoto A, Uemura T, Yamamichi G, Tomiyama E, Ishizuya Y, Yamamoto Y, Kato T, Kawashima A, Fujita K, Nonomura N.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 28 Issue: 3 Pages: 427-435
- DOI
  10.1007/s10147-022-02288-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24471
[Journal Article] Gut microbiome and prostate cancer.2022
- Author(s)
  Kazutoshi Fujita , Makoto Matsushita , Eri Banno , Marco A De Velasco , Koji Hatano , Norio Nonomura , Hirotsugu Uemura
- Journal Title
  
  International journal of urology
  
  Volume: 29 Issue: 8 Pages: 793-798
- DOI
  10.1111/iju.14894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09570, KAKENHI-PROJECT-23K24471
[Journal Article] Connecting the Dots Between the Gut IGF-1 Prostate Axis: A Role of IGF-1 in Prostate Carcinogenesis2022
- Author(s)
  Matsushita Makoto、Fujita Kazutoshi、Hatano Koji、De Velasco Marco A.、Uemura Hirotsugu、Nonomura Norio
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 13 Pages: 852382-852382
- DOI
  10.3389/fendo.2022.852382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09421, KAKENHI-PROJECT-23K24471
[Journal Article] Genomic Profiling of Prostate Cancer: An Updated Review2022
- Author(s)
  Hatano K, Nonomura N.
- Journal Title
  
  World J Mens Health
  
  Volume: 40 Issue: 3 Pages: 368-379
- DOI
  10.5534/wjmh.210072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24471
[Journal Article] High-fat diet promotes prostate cancer growth through histamine signaling.2022
- Author(s)
  Matsushita M, Fujita K, Hatano K, Hayashi T, Kayama H, Motooka D, Hase H, Yamamoto A, Uemura T, Yamamichi G, Tomiyama E, Koh Y, Kato T, Kawashima A, Uemura M, Nojima S, Imamura R, Mubeen A, Netto GJ, Tsujikawa K, Nakamura S, Takeda K, Morii E, Nonomura N.
- Journal Title
  
  Int J Cancer
  
  Volume: in press Issue: 4 Pages: 623-636
- DOI
  10.1002/ijc.34028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09689, KAKENHI-PROJECT-21K09421, KAKENHI-PROJECT-23K24471, KAKENHI-PROJECT-18K16693
[Journal Article] Localization and potential role of prostate microbiota2022
- Author(s)
  Okada K, Takezawa K, Tsujimura G, Imanaka T, Kuribayashi S, Ueda N, Hatano K, Fukuhara S, Kiuchi H, Fujita K, Motooka D, Nakamura S, Koyama Y, Shimada S, Nonomura N
- Journal Title
  
  Front Cell Infect Microbiol.
  
  Volume: 12 Pages: 1048319-1048319
- DOI
  10.3389/fcimb.2022.1048319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24471
[Journal Article] Firmicutes in Gut Microbiota Correlate with Blood Testosterone Levels in Elderly Men.2022
- Author(s)
  Matsushita M, Fujita K, Motooka D, Hatano K, Hata J, Nishimoto M, Banno E, Takezawa K, Fukuhara S, Kiuchi H, Pan Y, Takao T, Tsujimura A, Yachida S, Nakamura S, Obara W, Uemura H, Nonomura N.
- Journal Title
  
  World J Mens Health
  
  Volume: in press Issue: 3 Pages: 517-525
- DOI
  10.5534/wjmh.210190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09689, KAKENHI-PROJECT-23K24471
[Journal Article] Extracellular vesicles in prostate cancer: a narrative review2021
- Author(s)
  Hatano K, Fujita K
- Journal Title
  
  Transl Androl Urol
  
  Volume: - Issue: 4 Pages: 1890-1907
- DOI
  10.21037/tau-20-1210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18090
[Journal Article] Stereotactic Body Radiotherapy Using CyberKnife for Localized Low- and Intermediate-risk Prostate Cancer: Initial Report on a Phase I/II Trial2020
- Author(s)
  Nakamura R, Hirata T, Suzuki O, Otani K, Kai N, Hatano K, Fujita K, Uemura M, Imamura R, Tanaka K, Yoshioka Y, Nonomura N, Ogawa K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 40 Issue: 4 Pages: 2053-2057
- DOI
  10.21873/anticanres.14162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18090, KAKENHI-PROJECT-16H05389
[Journal Article] Intratumoral and s.c. injection of inactivated hemagglutinating virus of Japan envelope (GEN0101) in metastatic castration-resistant prostate cancer.2020
- Author(s)
  Fujita K, Kato T, Hatano K, Kawashima A, Ujike T, Uemura M, Imamura R, Okihara K, Ukimura O, Miki T, Nakajima T, Kaneda Y, Nonomura N.,
- Journal Title
  
  Cancer Sci.
  
  Volume: in press Issue: 5 Pages: 1692-1698
- DOI
  10.1111/cas.14366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KT0053, KAKENHI-PROJECT-19K09689, KAKENHI-PROJECT-20K18090
[Journal Article] Application of Anti-Inflammatory Agents in Prostate Cancer.2020
- Author(s)
  Hatano K, Fujita K, Nonomura N.
- Journal Title
  
  J Clin Med.
  
  Volume: 9 Issue: 8 Pages: 2680-2706
- DOI
  10.3390/jcm9082680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09689, KAKENHI-PROJECT-20K18090
[Presentation] 前立腺癌のポリジェニックリスクスコアは腸内細菌叢のリポ多糖経路と関連する2024
- Author(s)
  波多野　浩士
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-22K09447
[Presentation] Polygenetic risk score for prostate cancer is associated with lipopolysaccharide pathway in gut microbiome2024
- Author(s)
  Koji Hatano
- Organizer
  2024 AUA Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09447
[Presentation] Gut Microbiome corelated with Blood Testosterone Levels in Elderly Men2023
- Author(s)
  Kazutoshi Fujita Makoto Matsushita, Koji Hatano, Junya Hata , Azusa Yoshiyama , Mitsuhisa Nishimoto Shinichiro Fukuhara, Takafumi Minami, Shota Nakamura, Wataru Obara , Kazuhiro Yoshimura, Norio Nonomura Hirotsugu Uemura
- Organizer
  日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K08791
[Presentation] Lipopolysaccharide from high-fat diet-induced dysbiotic gut microbiota promotes inflammatory prostate cancer growth2023
- Author(s)
  松下　慎, 藤田和利, 波多野浩士, 冨山栄輔, 加藤大悟, 河嶋厚成, 植村元秀, 今村亮一, 辻川和丈, 中村昇太, 竹田　潔, 森井英一, 野々村祝夫
- Organizer
  第110回　日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] CRISPRスクリーニングによる放射線増感ターゲットの探索と前立腺癌への治療応用2023
- Author(s)
  波多野　浩士
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K18090
[Presentation] CRISPR screens reveal that DCLRE1c is a radiosensitization target for prostate cancer2023
- Author(s)
  岡　利樹、波多野浩士、二村圭祐、石津谷　祐、Liu Yutong、堀部祐輝、吉村明洋、谷　優、奥田洋平、山道　岳、冨山栄輔、山本致之、加藤大悟、河嶋厚成、藤田和利、野々村祝夫
- Organizer
  第82回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] The presence of lymph node metastases and time to castration resistance predict the therapeutic effect of enzalutamide for castration-resistant prostate cancer2023
- Author(s)
  岡　利樹、波多野浩士、奥田洋平、山本顕生、植村俊彦、山道　岳、冨山栄輔、石津谷　祐、山本致之、加藤大悟、河嶋厚成、藤田和利、野々村祝夫
- Organizer
  第110回　日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] 高齢者男性の血中テストステロン値に関係する腸内細菌叢の検討2023
- Author(s)
  藤田和利、松下　慎,　波多野浩士、秦淳也、吉山あずさ、兼平　貢、西本光寿、福原慎一郎、南高文、中村昇太、吉村一宏、野々村祝夫,　植村天受
- Organizer
  第110回　日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] Genome-wide CRISPR screens identify novel target genes which alter prostate cancer sensitivity to radiation therapy2023
- Author(s)
  Koji Hatano, Toshiki Oka, Keisuke Nimura, Yohei Okuda, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Eisuke Tomiyama, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Kazutoshi Fujita, Norio Nonomura
- Organizer
  Annual Meeting of the American Urological Association 2023
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] 放射線感受性と遺伝子相互作用の系統的マッピングによる前立腺癌の新規治療標的の同定2023
- Author(s)
  波多野浩士、岡　利樹、二村圭祐、石津谷祐、奥田洋平、植村俊彦、山道　岳、冨山栄輔、山本致之、加藤大悟、河嶋厚成、藤田和利、野々村祝夫
- Organizer
  第110回　日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] Shotgun metagenome analysis of gut microbiome in men with prostate cancer2023
- Author(s)
  Kazutoshi Fujita, Koji Hatano, Yoshihiko Tomofuji, Toshiki Oka, Makoto Matsushita, Mitsuhisa Nishimoto, Junya Hata、Akira Tsujimura、Wataru Obara、Yujiro Hayashi、Syunsuke Inoguchi、Shota Nakamura, Yukinori Okada, Hirotsugu Uemura, Norio Nonomura
- Organizer
  日本癌治療学会
- Data Source
  KAKENHI-PROJECT-23K08791
[Presentation] 腸内細菌叢由来 LPS はヒスタミン H1 受容体シグナル経路を介して前立腺癌増殖を促進する2022
- Author(s)
  藤田和利、松下慎、元岡大祐、長谷拓明、加藤大悟、波多野浩士、河嶋厚成、南高文、デベラスコマルコ、吉村一宏、ネットージョージ、辻川和丈、中村昇太、森井英一、植村天受、野々村祝夫
- Organizer
  第81回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] 前立腺癌　アップデート2022　―基礎研究から最新の臨床までー The role of gut microbiome in prostate cance2022
- Author(s)
  藤田和利、松下慎、波多野浩士、デベラスコマルコ、野々村祝夫、植村天受
- Organizer
  第81回　日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] 高脂肪食によるディスバイオシスが前立腺癌に及ぼす影響の解明2022
- Author(s)
  松下　慎、藤田和利、林　拓自、香山尚子、元岡大祐、長谷拓明、山本顕生、植村俊彦、山道　岳、冨山栄輔、洪　陽子、加藤大悟、波多野浩士、河嶋厚成、植村元秀、野島　聡、今村亮一、辻川和丈、中村昇太、竹田　潔、森井英一、野々村祝夫
- Organizer
  第37回前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] Lipopolysaccharide from dysbiotic gut microbiota due to high-fat diet promotes inflammatory prostate cancer growth through histamine H1 receptor signaling2022
- Author(s)
  Makoto Matsushita, Kazutoshi Fujita,Takuji Hayashi, Hisako Kayama, Daisuke Motooka, Hiroaki Hase, Toshihiro Uemura, Akinaru Yamamoto, Gaku Yamamichi, Eisuke Tomiyama, Yoko Koh, Taigo Kato, Koji Hatano, Atsunari Kawashima,・・・・Eiichi Morii, Norio
- Organizer
  Annual meeting of the American Urological Association
- Data Source
  KAKENHI-PROJECT-23K24471
[Presentation] 臨床的意義のある前立腺癌の診断における再生検時の前立腺multiparametric MRIの有用性2020
- Author(s)
  波多野浩士, 河嶋厚成, 加藤大悟, 氏家　剛, 藤田和利, 植村元秀, 野々村祝夫
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K18090

1. 藤田和利 (50636181)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
2. 二村圭祐 (00462713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 野々村祝夫 (30263263)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
4. 中村昇太 (90432434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. 岡利樹 (60964385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 柴知史 (00797003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山田拓司 (10437262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 谷内田真一 (20359920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松下慎 (40824785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. 岡田随象 (70727411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. デベラスコマルコ (20449838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 植村天受 (90213397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. DEVELASCO Marco

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 三善英知

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 金田安史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hatano Koji 波多野 浩士

Research Projects

Research Products

Co-Researchers

運動と食生活による前立腺癌の増殖制御の解明と革新的ながん予防への展開Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

機能的スクリーニングに基づく前立腺癌の放射線感受性メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腫瘍微小環境における多因子間相互作用ネットワーク定量的検出への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腸内細菌叢によるアンドロゲンシグナル経路を介した去勢抵抗性前立腺癌進展機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生活習慣による代謝物プロファイル変化を介する前立腺癌の増殖制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Diagnostic strategy for prostate cancer based on multifaceted analyses of genetic background, life style and gut microbiome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CRISPR screens identify novel targets that sensitize prostate cancer cells to ionizing radiation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Emerging Relationship between the Gut Microbiome and Prostate Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Gut-Prostate Axis: A New Perspective of Prostate Cancer Biology through the Gut Microbiome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic significance of serum fucosylated pro-haptoglobin in advanced renal cell carcinoma patients treated with immune checkpoint inhibitors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The presence of lymph node metastases and time to castration resistance predict the therapeutic effect of enzalutamide for castration-resistant prostate cancer.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gut microbiome and prostate cancer.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Connecting the Dots Between the Gut IGF-1 Prostate Axis: A Role of IGF-1 in Prostate Carcinogenesis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genomic Profiling of Prostate Cancer: An Updated Review2022

Author(s)

Journal Title

DOI

Hatano Koji 波多野浩士