Ichinose Toru 一ノ瀬亨

Researcher Number	60778091
Affiliation (based on the past Project Information) *help	2021: 名古屋大学, 医学系研究科, 研究員 2016 – 2018: 名古屋大学, 医学系研究科, 研究員
Review Section/Research Field	Principal Investigator Otorhinolaryngology / General surgery Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 癌 / 腫瘍溶解性ウイルス / 頭頸部がん / 免疫チェックポイント / サイトカインシグナル / 癌抗原 / TCR遺伝子改変T細胞 / 免疫細胞療法 Except Principal Investigator 癌免疫 / 腫瘍溶解性ウイルス

Oncolytic virus targeting tumor associated mesenchymal stem cells
- Principal Investigator
  
  Matsumura Shigeru
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagoya University
Development of combination therapy of cytokine signaling suppressor virus and anti-PD-L1 antibodyPrincipal Investigator
- Principal Investigator
  
  Ichinose Toru
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Nagoya University
癌抗原発現ウイルスと癌抗原特異的T細胞の併用療法の開発Principal Investigator
- Principal Investigator
  
  一ノ瀬亨
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General surgery
- Research Institution
  Nagoya University

All 2021 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 遺伝子医学MOOK 31号がん免疫療法 - What's now and what's next? 第2章の4の3) 腫瘍溶解性ウイルス HF10による再発乳がん多発結節症例, 切除不能進行膵がん症例に対する臨床研究2017
- Author(s)
  粕谷英樹, 直江吉則, 一ノ瀬亨, 廣岡芳樹, 後藤秀実, 田中舞紀
- Total Pages
  294
- Publisher
  (株)メディカルドゥ
- Data Source
  KAKENHI-PROJECT-17K16907
[Journal Article] C-REV Retains High Infectivity Regardless of the Expression Levels of cGAS and STING in Cultured Pancreatic Cancer Cells2021
- Author(s)
  Daishi Morimoto, Shigeru Matsumura, Itzel Bustos-Villalobos, Patricia Angela Sibal, Toru Ichinose, Yoshinori Naoe, Ibrahim Ragab Eissa, ohamed Abdelmoneim, Nobuaki Mukoyama, Noriyuki Miyajima, Maki Tanaka, Yasuhiro Kodera and Hideki Kasuya
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 6 Pages: 1-16
- DOI
  10.3390/cells10061502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02691, KAKENHI-PROJECT-21H02999, KAKENHI-PROJECT-19H03434
[Journal Article] Oncolytic herpes simplex virus HF10 (canerpaturev, C-REV) promotes accumulation of CD8+PD-1- tumor-infiltrating T cells in PD-L1 enriched tumor microenvironment.2021
- Author(s)
  Eissa I.R., Mukoyama N., Abdelmoneim, M., Naoe, Y., Matsumura, S., Bustos-Villalobos I., Ichinose T., Miyajima N., Morimoto D., Tanaka M., Fujimoto, Y., Kodera Y., Kasuya H.
- Journal Title
  
  Int. J. Cancer
  
  Volume: 1 Issue: 1 Pages: 1-14
- DOI
  10.1002/ijc.33550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02691, KAKENHI-PROJECT-20K16438, KAKENHI-PROJECT-21H02999, KAKENHI-PROJECT-19H03434
[Journal Article] The Current Status and Future Prospects of Oncolytic Viruses in Clinical Trials against Melanoma, Glioma, Pancreatic, and Breast Cancers2018
- Author(s)
  Eissa Ibrahim、Bustos-Villalobos Itzel、Ichinose Toru、Matsumura Shigeru、Naoe Yoshinori、Miyajima Noriyuki、Morimoto Daishi、Mukoyama Nobuaki、Zhiwen Wu、Tanaka Maki、Hasegawa Hitoki、Sumigama Seiji、Aleksic Branko、Kodera Yasuhiro、Kasuya Hideki
- Journal Title
  
  Cancers
  
  Volume: 10 Issue: 10 Pages: 356-356
- DOI
  10.3390/cancers10100356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15274, KAKENHI-PROJECT-16H05413, KAKENHI-PROJECT-18H02691, KAKENHI-PROJECT-17K19696, KAKENHI-PROJECT-17K16907
[Journal Article] A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer2018
- Author(s)
  Hirooka Yoshiki、Kasuya Hideki、Ishikawa Takuya、Kawashima Hiroki、Ohno Eizaburo、Villalobos Itzel B.、Naoe Yoshinori、Ichinose Toru、Koyama Nobuto、Tanaka Maki、Kodera Yasuhiro、Goto Hidemi
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 596-596
- DOI
  10.1186/s12885-018-4453-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15274, KAKENHI-PROJECT-16H05413, KAKENHI-PROJECT-17K19696, KAKENHI-PROJECT-17K16907
[Journal Article] Curative effect of HF10 on liver and peritoneal metastasis mediated by host antitumor immunity2017
- Author(s)
  Hotta Y, Kasuya H, Bustos I, Naoe Y, Ichinose T, Tanaka M, Kodera Y
- Journal Title
  
  Oncolytic Virotherapy
  
  Volume: 6 Pages: 31-38
- DOI
  10.2147/ov.s127179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05413, KAKENHI-PROJECT-16K15611, KAKENHI-PROJECT-17K16907
[Presentation] Combination therapy of Cetuximab and CANERPATUREV suppresses human colorectal cancer growth2019
- Author(s)
  Shigeru Matsumura, Zhiwen Wu, Toru Ichinose, Yoshinori Naoe, Itzel Bustos Villalobos, Ibrahim Ragab Eissa, Suguru Yamada, Yasuhiro Kodera, Maki Tanaka, and Hideki Kasuya
- Organizer
  日本遺伝子細胞治療学会
- Data Source
  KAKENHI-PROJECT-18H02691
[Presentation] 大腸癌モデルにおけるセツキシマブとC-REVとの併用治療効果について2019
- Author(s)
  Shigeru Matsumura, Zhiwen Wu, Toru Ichinose, Yoshinori Naoe, Itzel Bustos Villalobos, Ibrahim Ragab Eissa, Suguru Yamada, Yasuhiro Kodera, Maki Tanaka, and Hideki Kasuya
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02691
[Presentation] Combination of cetuximab and oncolytic virus canepaturev synergistically inhibits human colorectal cancer growth2019
- Author(s)
  Shigeru Matsumura, Zhiwen Wu, Toru Ichinose, Yoshinori Naoe, Itzel Bustos Villalobos, Ibrahim Ragab Eissa, Suguru Yamada, Yasuhiro Kodera, Maki Tanaka, and Hideki Kasuya
- Organizer
  癌免疫学会
- Data Source
  KAKENHI-PROJECT-18H02691
[Presentation] STING is dispensable for low susceptibility to C-REV (HF10) in pancreatic cancer cell lines2018
- Author(s)
  Matsumura S, Morimoto D, Naoe Y, Ichinose T, Eissa IR, Tanaka M, Kodera Y, Kasuya H
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02691
[Presentation] The synergistic effect of the combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus HF102018
- Author(s)
  Nobuaki Mukoyama, Ibrahim Eissa, Yoshinori Naoe, Toru Ichinose, Shigeru Matsumura, Itzel Bustos, Wu Zhiwen, Noriyuki Miyajima, Daishi Morimoto, Maki Tanaka, Yasushi Fujimoto, Michihiko Sone, Yasuhiro Kodera, Hideki Kasuya
- Organizer
  第24回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] The synergistic effect of the combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus Canerpaturev(C-REV)2018
- Author(s)
  Yoshinori Naoe, Nobuaki Mukoyama, Ibrahim Eissa, Toru Ichinose, Shigeru Matsumura, Itzel Bustos, Wu Zhiwen, Noriyuki Miyajima, Daishi Morimoto, Maki Tanaka, Yasushi Fujimoto, Michihiko Sone, Yasuhiro Kodera, Hideki Kasuya
- Organizer
  第56回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] Combination therapy of oncolytic HSV HF10 and immune checkpoint inhibitor2018
- Author(s)
  H Kasuya, Y Naoe, S Matsumura, I Bustos, T Ichinose, I Eissa, W Zhiwen, N Miyajima, D Morimoto, M Tanaka
- Organizer
  International Oncolytic Virus Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] STING is dispensable for low susceptibility to C-REV (HF10) in pancreatic cancer cell lines2018
- Author(s)
  Matsumura S, Morimoto D, Naoe Y, Ichinose T, Eissa IR, Tanaka M, Kodera Y, Kasuya H
- Organizer
  4th Annual Oncolytic virotherapy summit
- Data Source
  KAKENHI-PROJECT-18H02691
[Presentation] ヒト大腸がんモデルにおけるセツキシマブとの併用による腫瘍溶解性ウイルスHF10 の抗腫瘍効果2017
- Author(s)
  呉智聞, 一ノ瀬亨, 駱晨虹, 直江吉則, イッツェル・ブストス・ビジャロボス, 山田豪, 藤井努, 杉本博行, 森本大士, 向山宣昭, 小寺泰弘, 田中舞紀, 粕谷英樹
- Organizer
  第117 回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] Systemic therapeutic potential of oncolytic herpes simplex virus HF10 adsorbed on antigen-specific lymphocytes2017
- Author(s)
  Ichinose T, Naoe Y, Nassr E. I. R, Luo C, Villalobos I. B, Zhiwen W, Mukoyama N, Miyajima N, Morimoto D, Yamada S, Fujii T, Sugimoto H, Tanaka M, Kodera Y, Kasuya H.
- Organizer
  第23回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] ヒト膵癌異種移植モデルにおけるnab-Paclitaxel（nab-PTX）と腫瘍溶解性単純ヘルペスウイルスHF10 との併用療法2017
- Author(s)
  森本大士, 直江吉則, 一ノ瀬亨, Bustos Itzel, 神田光郎, 丹羽由紀子, 岩田直樹, 林真路, 小林大介, 田中千恵, 山田豪, 中山吾郎, 杉本博行, 小池聖彦, 藤原道隆, 藤井努, 田中舞紀, 粕谷英樹, 小寺泰弘
- Organizer
  第117 回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] HF10 ウイルス療法におけるin situ vaccination効果についての検討2017
- Author(s)
  粕谷英樹, 直江吉則, Bustos Itzel, 一ノ瀬亨, 森本大士, 向山宣昭, 呉智聞, 藤井努, 小寺泰弘, 田中舞紀
- Organizer
  第117 回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] Combination therapy of oncolytic herpes virus and anti-angiogenesis agent (bevacizumab) against human gastric cancer xenograft2017
- Author(s)
  H. Kasuya, G. Tan, C. Luo, T. Ichinose, I. Bustos, Y. Naoe
- Organizer
  EACR-AACR-SIC Special Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] Combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus HF102017
- Author(s)
  Mukoyama N, Naoe Y, Ichinose T, Nassr E. I. R, Luo C, Villalobos I. B, Zhiwen W, Miyajima N, Morimoto D, Tanaka M, Fujimoto Y, Sone M, Kodera Y, Kasuya H.
- Organizer
  第23回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16907
[Presentation] Most resent clinical trial data using HF10 for 9 patients with non resectable pancreatic cancer2016
- Author(s)
  Yoshinori Naoe, Toru Ichinose, Chenhong Luo, Wu Zhiwen, Nobuaki Mukoyama, Noriyuki Miyajima, Daishi Morimoto, Maki Tanaka, Hideki Kasuya
- Organizer
  The 10th International Meeting on Replicating Oncolytic Virus Therapeutics
- Place of Presentation
  バンクーバー（カナダ）
- Year and Date
  2016-10-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06869

1. Matsumura Shigeru (60523511)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 粕谷英樹 (00402636)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
3. 直江吉則 (50392048)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
4. BUSTOS itzel

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. EISSA ibrahim

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. KODERA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ichinose Toru 一ノ瀬 亨

Research Projects

Research Products

Co-Researchers

Oncolytic virus targeting tumor associated mesenchymal stem cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of combination therapy of cytokine signaling suppressor virus and anti-PD-L1 antibodyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌抗原発現ウイルスと癌抗原特異的T細胞の併用療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 遺伝子医学MOOK 31号 がん免疫療法 - What's now and what's next? 第2章の4の3) 腫瘍溶解性ウイルス HF10による再発乳がん多発結節症例, 切除不能進行膵がん症例に対する臨床研究2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] C-REV Retains High Infectivity Regardless of the Expression Levels of cGAS and STING in Cultured Pancreatic Cancer Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncolytic herpes simplex virus HF10 (canerpaturev, C-REV) promotes accumulation of CD8+PD-1- tumor-infiltrating T cells in PD-L1 enriched tumor microenvironment.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Current Status and Future Prospects of Oncolytic Viruses in Clinical Trials against Melanoma, Glioma, Pancreatic, and Breast Cancers2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Curative effect of HF10 on liver and peritoneal metastasis mediated by host antitumor immunity2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Combination therapy of Cetuximab and CANERPATUREV suppresses human colorectal cancer growth2019

Author(s)

Organizer

Data Source

[Presentation] 大腸癌モデルにおけるセツキシマブとC-REVとの併用治療効果について2019

Author(s)

Organizer

Data Source

[Presentation] Combination of cetuximab and oncolytic virus canepaturev synergistically inhibits human colorectal cancer growth2019

Author(s)

Organizer

Data Source

[Presentation] STING is dispensable for low susceptibility to C-REV (HF10) in pancreatic cancer cell lines2018

Author(s)

Organizer

Data Source

[Presentation] The synergistic effect of the combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus HF102018

Author(s)

Organizer

Data Source

[Presentation] The synergistic effect of the combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus Canerpaturev(C-REV)2018

Author(s)

Organizer

Data Source

[Presentation] Combination therapy of oncolytic HSV HF10 and immune checkpoint inhibitor2018

Author(s)

Organizer

Data Source

Ichinose Toru 一ノ瀬亨

[Book] 遺伝子医学MOOK 31号がん免疫療法 - What's now and what's next? 第2章の4の3) 腫瘍溶解性ウイルス HF10による再発乳がん多発結節症例, 切除不能進行膵がん症例に対する臨床研究2017