Kondo Kenta 近藤健太

… Alternative Names

KONDO Kenta 近藤健太

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Researcher Number	60779974
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 滋賀医科大学, 医学部, 助教 2020 – 2021: 滋賀医科大学, 医学部, 特任助教 2018: 徳島大学, 先端酵素学研究所(プロテオ), 専門研究員 2018: 徳島大学, 先端酵素学研究所(プロテオ), 徳島大学専門研究員 2017: 徳島大学, 先端酵素学研究所(プロテオ), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / 0901:Oncology and related fields / Immunology
Keywords	Principal Investigator エピジェネティクス / ビタミンC / CD8+ T細胞 / Batf3 / 免疫記憶 / DNA脱メチル化 / エピゲノム / がんモデルサル / TCR / 再生T細胞 … More / iPS細胞 / 癌免疫療法 / カニクイザル / T細胞選択 / 獲得免疫 / 免疫学 / 負の選択 / 正の選択 / T細胞 / 胸腺 Less

ビタミンCのDNA脱メチル化促進作用がCD8+ T細胞の免疫応答に及ぼす影響の解明Principal Investigator
- Principal Investigator
  
  近藤健太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Shiga University of Medical Science
Elucidation of the mechanism of memory T cell differentiation by vitamin C through upregulation of Galectin3Principal Investigator
- Principal Investigator
  
  Kondo Kenta
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Shiga University of Medical Science
Generation of cancer model monkeys and development of novel cancer immunotherapy using regenerated T cells derived from iPS cellsPrincipal Investigator
- Principal Investigator
  
  Kondo Kenta
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Shiga University of Medical Science
Regulation of negative selection by fine-tuning TCR responsiveness through positive selectionPrincipal Investigator
- Principal Investigator
  
  KONDO Kenta
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokushima

All 2024 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Isolation of TCR genes with tumor-killing activity from tumor-infiltrating and circulating lymphocytes in a tumor rejection cynomolgus macaque model2022
- Author(s)
  Terada Koji、Kondo Kenta、Ishigaki Hirohito、Nagashima Ayaka、Satooka Hiroki、Nagano Seiji、Masuda Kyoko、Kawamura Teruhisa、Hirata Takako、Ogasawara Kazumasa、Itoh Yasushi、Kawamoto Hiroshi、Agata Yasutoshi
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 24 Pages: 77-86
- DOI
  10.1016/j.omto.2021.12.003
- NAID
  120007182844
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07171, KAKENHI-PROJECT-19K07621, KAKENHI-PROJECT-19H01140, KAKENHI-PROJECT-19K07712, KAKENHI-PROJECT-20K22840
[Journal Article] Thymus machinery for T-cell selection2019
- Author(s)
  Kondo K, Ohigashi I, Takahama Y
- Journal Title
  
  International Immunology
  
  Volume: 31 Issue: 3 Pages: 119-125
- DOI
  10.1093/intimm/dxy081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08884, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-17K15727
[Journal Article] Establishment of a novel platform cell line for efficient and precise evaluation of T cell receptor functional avidity2018
- Author(s)
  Morimoto Soyoko、Fujiki Fumihiro、Kondo Kenta、Nakajima Hiroko、Kobayashi Yoshiki、Inatome Miki、Aoyama Nao、Nishida Yuya、Tsuboi Akihiro、Oka Yoshihiro、Nishida Sumiyuki、Nakata Jun、Hosen Naoki、Oji Yusuke、Sugiyama Haruo
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 75 Pages: 34132-34141
- DOI
  10.18632/oncotarget.26139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07215, KAKENHI-PROJECT-17K07216, KAKENHI-PROJECT-16K11136, KAKENHI-PROJECT-17K15727
[Journal Article] Antigen processing and presentation in the thymus: implications for T cell repertoire selection2017
- Author(s)
  Kondo Kenta、Takada Kensuke、Takahama Yousuke
- Journal Title
  
  Current Opinion in Immunology
  
  Volume: 46 Pages: 53-57
- DOI
  10.1016/j.coi.2017.03.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15727, KAKENHI-PROJECT-16H02630
[Presentation] ビタミン C による DNA 脱メチル化促進作用がCD8 T 細胞(キラー T 細胞)に及ぼす影響の解明2024
- Author(s)
  近藤健太，長谷川達矢，寺田晃士，口分田美奈，新田信人，縣保年
- Organizer
  日本ビタミン学会第 75 回大会
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] iPS細胞から再生したT細胞の抗腫瘍活性に対するサイトカインの影響2024
- Author(s)
  新田信人、近藤健太、寺田晃士、永野誠治、河本宏、縣保年
- Organizer
  第32回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] Batf ファミリー転写因子の過剰発現によるCD8+ T細胞の機能強化2024
- Author(s)
  口分田美奈、近藤健太、寺田晃士、縣保年
- Organizer
  第36回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] Vitamin C treatment enhances the immune responses of CD8+ T cells by upregulation of Batf3.2024
- Author(s)
  Kenta Kondo, Koji Terada, Yasutoshi Agata
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] iPS 細胞から再生した T 細胞の抗腫瘍活性に対するサイトカインの影響2024
- Author(s)
  新田信人、近藤健太、寺田晃士、永野誠治、三宅亨、谷眞至、河本宏、縣保年
- Organizer
  第36回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] Batfファミリー転写因子の過剰発現によるCD8+ T細胞の機能強化2024
- Author(s)
  口分田美奈、近藤健太、寺田晃士、縣保年
- Organizer
  第32回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] Vitamin C treatment promotes the persistence and immune responses of CD8 + T cells.2022
- Author(s)
  Kenta Kondo, Tatsuya Hasegawa, Koji Terada, Yasutoshi Agata
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] ビタミンCはCD8 T細胞の生存能を亢進させる2022
- Author(s)
  近藤健太、長谷川達矢、寺田晃士、口分田美奈、新田信人、前田菜摘、奥崎大介、縣保年
- Organizer
  第31回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-22K15488
[Presentation] ビタミンCによるCD8 T細胞 (キラーT細胞) の機能制御機構の解明2022
- Author(s)
  近藤健太、長谷川達矢、寺田晃士、口分田美奈、新田信人、縣保年
- Organizer
  第165回ビタミンＣ研究委員会
- Invited
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] “TCRカセット法”の開発 : がん抗原特異的TCR遺伝子を内在性TCR遺伝子座へ効率よく導入する2021
- Author(s)
  寺田晃士、永野誠治、近藤健太、増田喬子、河本　宏、縣　保年
- Organizer
  第30回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] Vitamin C alters gene expression of CD8+ T cells through DNA demethylation.2021
- Author(s)
  Kenta Kondo, Tatsuya Hasegawa, Koji Terada, Yasutoshi Agata
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] Development of “TCR cassette method”: Regeneration of CTLs from iPSCs in which tumor-antigen specific TCR genes can be efficiently introduced into the endogenous TCR locus by cassette exchange.2021
- Author(s)
  Koji Terada, Kenta Kondo, Seiji Nagano, Kyoko Masuda, Hiroshi Kawamoto, 〇 Yasutoshi Agata
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] Isolation of TCR genes with tumor-killing activity from tumor-infiltrating lymphocytes in a tumor rejection cynomolgus macaque model.2021
- Author(s)
  Koji Terada, Kenta Kondo, Hirohito Ishigaki, Ayaka Nagashima, Hiroki Satooka, Seiji Nagano, Kyoko Masuda, Teruhisa Kawamura, Takako Hirata, Kazumasa Ogasawara, Yasushi Itoh, Hiroshi Kawamoto, Yasutoshi Agata
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] カニクイザルの腫瘍浸潤T細胞から腫瘍殺傷能をもつTCR遺伝子を単離する2021
- Author(s)
  近藤健太、寺田晃士、石垣宏仁、長嶋彩花、里岡大樹、永野誠治、増田喬子、川村晃久、平田多佳子、小笠原一誠、伊藤　靖、河本　宏、縣　保年
- Organizer
  第30回 Kyoto T Cell Conference
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] "TCRカセット法"の開発：がん抗原特異的TCR遺伝子を内在性TCR遺伝子座へ効率よく導入できるiPS細胞から細胞傷害性T細胞を再生する2020
- Author(s)
  寺田晃士、近藤健太、永野誠治、増田喬子、河本宏、縣保年
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] カニクイザルの腫瘍浸潤T細胞から腫瘍殺傷能を有するTCR遺伝子を単離する2020
- Author(s)
  寺田晃士、近藤健太、石垣宏仁、里岡大樹、永野誠治、増田喬子、平田多佳子、小笠原一誠、伊藤靖、河本宏、縣保年
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] カニクイザルの腫瘍拒絶モデルにおける腫瘍浸潤T細胞からの腫瘍殺傷能をもつTCR遺伝子の単離2020
- Author(s)
  寺田晃士、石垣宏仁、近藤健太、長嶋彩花、里岡大樹、永野誠治、増田喬子、川村晃久、河本宏、平田多佳子、小笠原一誠、伊藤靖、縣保年
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] ゲノム編集とカセット交換法を用いたがん抗原特異的 TCR 遺伝子導入法の開発2020
- Author(s)
  寺田晃士、近藤健太、永野誠治、前田卓也、増田喬子、河本宏、縣保年
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K22840
[Presentation] Thymoproteasome-dependent positive selection conditions in vivo immune responses in CD8+ T cells2017
- Author(s)
  Kenta Kondo, Kensuke Takada, Yousuke Takahama
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K15727

1. OHIGASHI Izumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. FUJIKI Fumihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 縣保年

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kondo Kenta 近藤 健太

KONDO Kenta 近藤 健太

Research Projects

Research Products

Co-Researchers

ビタミンCのDNA脱メチル化促進作用がCD8+ T細胞の免疫応答に及ぼす影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of memory T cell differentiation by vitamin C through upregulation of Galectin3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of cancer model monkeys and development of novel cancer immunotherapy using regenerated T cells derived from iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of negative selection by fine-tuning TCR responsiveness through positive selectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Isolation of TCR genes with tumor-killing activity from tumor-infiltrating and circulating lymphocytes in a tumor rejection cynomolgus macaque model2022

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Thymus machinery for T-cell selection2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a novel platform cell line for efficient and precise evaluation of T cell receptor functional avidity2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antigen processing and presentation in the thymus: implications for T cell repertoire selection2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] ビタミン C による DNA 脱メチル化促進作用がCD8 T 細胞(キラー T 細胞)に及ぼす影響の解明2024

Author(s)

Organizer

Data Source

[Presentation] iPS細胞から再生したT細胞の抗腫瘍活性に対するサイトカインの影響2024

Author(s)

Organizer

Data Source

[Presentation] Batf ファミリー転写因子の過剰発現によるCD8+ T細胞の機能強化2024

Author(s)

Organizer

Data Source

[Presentation] Vitamin C treatment enhances the immune responses of CD8+ T cells by upregulation of Batf3.2024

Author(s)

Organizer

Data Source

[Presentation] iPS 細胞から再生した T 細胞の抗腫瘍活性に対するサイトカインの影響2024

Author(s)

Organizer

Data Source

[Presentation] Batfファミリー転写因子の過剰発現によるCD8+ T細胞の機能強化2024

Author(s)

Organizer

Data Source

[Presentation] Vitamin C treatment promotes the persistence and immune responses of CD8 + T cells.2022

Author(s)

Organizer

Data Source

[Presentation] ビタミンCはCD8 T細胞の生存能を亢進させる2022

Author(s)

Kondo Kenta 近藤健太

KONDO Kenta 近藤健太