Tsutsumi Motosuke 堤元佐

Researcher Number	60782422
Other IDs
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 医用工学, 助教
Affiliation (based on the past Project Information) *help	2023: 大学共同利用機関法人自然科学研究機構(機構直轄研究施設), 生命創成探究センター, 特任助教 2019 – 2022: 大学共同利用機関法人自然科学研究機構(新分野創成センター、アストロバイオロジーセンター、生命創成探究, 生命創成探究センター, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 28040:Nanobioscience-related Except Principal Investigator Basic Section 44040:Morphology and anatomical structure-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
Keywords	Principal Investigator イメージング / 超解像顕微鏡 / 蛍光顕微鏡 / in vivo / 深部観察 / ３次元超解像 / 深部イメージング / ２光子顕微鏡 / スフェロイド / 促進拡散 … More / 転写因子 / 生体超解像イメージング / 先端蛍光顕微鏡 / 生体イメージング / 高速超解像イメージング / 深部超解像イメージング … More Except Principal Investigator 進化 / 植物細胞 / 微小管 / 細胞伸長 / 線虫C. エレガンス / 自動追跡 / 高速三次元イメージング / カルシウムイメージング / イメージング Less

On the origin of polarized cell growth via analyses of tobacco culture cells and Closterium cells
- Principal Investigator
  
  村田隆
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  Kanagawa Institute of Technology
Establishment of a novel deep 3D super-resolution observation method for living organisms by spatiotemporal fluorescence correlation analysisPrincipal Investigator
- Principal Investigator
  
  堤元佐
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  National Institutes of Natural Sciences
自動追跡ロボット技術と超高速三次元イメージング技術の統合による脳動作原理の解明
- Principal Investigator
  
  木村幸太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Nagoya City University
Visualization of facilitated diffusion of transcription-factor by utilizing novel high-speed super-resolution microscopyPrincipal Investigator
- Principal Investigator
  
  Tsutsumi Motosuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Multibeam continuous axial scanning two-photon microscopy for in vivo volumetric imaging in mouse brain2024
- Author(s)
  Ataka Mitsutoshi、Otomo Kohei、Enoki Ryosuke、Ishii Hirokazu、Tsutsumi Motosuke、Kozawa Yuichi、Sato Shunichi、Nemoto Tomomi
- Journal Title
  
  Biomedical Optics Express
  
  Volume: 15 Issue: 2 Pages: 1089-1089
- DOI
  10.1364/boe.514826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14578, KAKENHI-PROJECT-22K21353, KAKENHI-PROJECT-22KK0100, KAKENHI-PROJECT-21K19346, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H05669, KAKENHI-PROJECT-20H03425, KAKENHI-PROJECT-23K24019
[Journal Article] Fluorescence radial fluctuation enables two-photon super-resolution microscopy2023
- Author(s)
  Tsutsumi Motosuke、Takahashi Taiga、Kobayashi Kentaro、Nemoto Tomomi
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 17
- DOI
  10.3389/fncel.2023.1243633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K14578, KAKENHI-PROJECT-22K21353, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H05669
[Journal Article] Absorption, fluorescence, and two-photon excitation ability of 5-phenyl-13-arylisoindolo[2,1-a]quinolines prepared by one-pot reaction of ring-closing metathesis and 1,3-dipolar cycloaddition2023
- Author(s)
  Ramon Avena Francisco、Wada Yuki、Ishii Hirokazu、Watakabe Yuki、Tsutsumi Motosuke、Jang Kwangkyun、Otomo Kohei、Qiao Lin、Fujii Yuki、Tsujino Hirofumi、Tsutsumi Yasuo、Nemoto Tomomi、Arisawa Mitsuhiro
- Journal Title
  
  Dyes and Pigments
  
  Volume: 212 Pages: 111118-111118
- DOI
  10.1016/j.dyepig.2023.111118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19346, KAKENHI-PROJECT-22K14578, KAKENHI-PROJECT-20H05669, KAKENHI-PROJECT-23K24019, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-15KT0063
[Journal Article] 3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images2021
- Author(s)
  Wen Chentao、Miura Takuya、Voleti Venkatakaushik、Yamaguchi Kazushi、Tsutsumi Motosuke、Yamamoto Kei、Otomo Kohei、Fujie Yukako、Teramoto Takayuki、Ishihara Takeshi、Aoki Kazuhiro、Nemoto Tomomi、Hillman Elizabeth MC、Kimura Koutarou D
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.59187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06591, KAKENHI-PROJECT-19K15406, KAKENHI-INTERNATIONAL-16K21735, KAKENHI-ORGANIZER-16H06535, KAKENHI-PLANNED-19H05798, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-18H02444, KAKENHI-PROJECT-19J20538, KAKENHI-PLANNED-16H06545, KAKENHI-ORGANIZER-19H05794, KAKENHI-PROJECT-20H05669, KAKENHI-PROJECT-19H03326, KAKENHI-PROJECT-17H06113
[Journal Article] FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells2021
- Author(s)
  Kamasaki Tomoko、Miyazaki Yumi、Ishikawa Susumu、Hoshiba Kazuya、Kuromiya Keisuke、Tanimura Nobuyuki、Mori Yusuke、Tsutsumi Motosuke、Nemoto Tomomi、Uehara Ryota、Suetsugu Shiro、Itoh Toshiki、Fujita Yasuyuki
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 9 Pages: 102994-102994
- DOI
  10.1016/j.isci.2021.102994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06638, KAKENHI-PROJECT-20K21411, KAKENHI-PROJECT-19K15406, KAKENHI-ORGANIZER-21H05283, KAKENHI-PLANNED-21H05285, KAKENHI-PROJECT-20H05669, KAKENHI-PROJECT-21H05039, KAKENHI-PROJECT-19J40132, KAKENHI-PROJECT-20K07559, KAKENHI-PROJECT-20K15785, KAKENHI-PROJECT-21H05047, KAKENHI-PROJECT-20H03252, KAKENHI-PROJECT-20KK0341
[Journal Article] Adaptive Optical Two-Photon Microscopy for Surface-Profiled Living Biological Specimens2020
- Author(s)
  Yamaguchi Kazushi、Otomo Kohei、Kozawa Yuichi、Tsutsumi Motosuke、Inose Tomoko、Hirai Kenji、Sato Shunichi、Nemoto Tomomi、Uji-i Hiroshi
- Journal Title
  
  ACS Omega
  
  Volume: 6 Issue: 1 Pages: 438-447
- DOI
  10.1021/acsomega.0c04888
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06591, KAKENHI-PROJECT-20K21165, KAKENHI-PROJECT-19K15406, KAKENHI-PROJECT-20H00523, KAKENHI-PROJECT-17H03003, KAKENHI-PROJECT-20H05669
[Presentation] 時空間蛍光相関解析による２光子深部超解像イメージング2023
- Author(s)
  堤元佐、髙橋泰伽、小林健太郎、根本知己
- Organizer
  生理研研究会 “細胞システム理解のためのシグナル応答原理解明の最前線”
- Invited
- Data Source
  KAKENHI-PROJECT-22K14578
[Presentation] 時空間蛍光相関解析による生体深部超解像観察法の確立2023
- Author(s)
  堤元佐、髙橋泰伽、小林健太郎、根本知己
- Organizer
  AMED精神・神経疾患領域/早期ライフ連携推進ワークショップ
- Data Source
  KAKENHI-PROJECT-22K14578
[Presentation] 時空間蛍光相関解析による２光子深部超解像イメージング2023
- Author(s)
  堤元佐、髙橋泰伽、小林健太郎、根本知己
- Organizer
  名大医・生理研合同シンポジウム2023
- Data Source
  KAKENHI-PROJECT-22K14578
[Presentation] Fluorescence Radial Fluctuation Enables Two-photon Super-Resolution Microscopy2023
- Author(s)
  Tsutsumi M., Takahashi T., Kobayashi K., Nemoto T.
- Organizer
  Retreat for Multidimensional Analysis of Memory Mechanisms
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K14578
[Presentation] Fluorescence Radial Fluctuation Enables Two-photon Super-Resolution Microscopy2023
- Author(s)
  Tsutsumi M., Takahashi T., Kobayashi K., Nemoto T.
- Organizer
  The 7th Australia-Belgium-Japan joint symposium on excitonics and cellular communication
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K14578
[Presentation] "接着"を見る、視る、観る -蛍光顕微鏡技術の最前線-2022
- Author(s)
  堤元佐
- Organizer
  日本接着学会東北・北海道地区合同セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K14578
[Presentation] Image analysis based super-resolution two-photon microscopy for in vivo imaging2022
- Author(s)
  Tsutsumi M, Nemoto T
- Organizer
  第11回生理研-霊長研-新潟脳研　合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] In vivo super-resolution two-photon microscopy based on spatiotemporal correlation analysis2022
- Author(s)
  Tsutsumi Motosuke
- Organizer
  5th ExCELLS retreat for young researchers
- Data Source
  KAKENHI-PROJECT-22K14578
[Presentation] 光学顕微鏡の観察の新展開－光学分解能を超える観察とリモート観察－2022
- Author(s)
  堤元佐
- Organizer
  北海道大学技術支援・設備共用コアステーションオンライン会議
- Invited
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] Image analysis based super-resolution two-photon microscopy for in vivo imaging2022
- Author(s)
  Tsutsumi M
- Organizer
  第4回 ExCELLS若手交流リトリート
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] TP-SRRF, Image analysis based super-resolution two-photon microscopy for deep imaging2021
- Author(s)
  Motosuke Tsutsumi
- Organizer
  第3回 ExCELLS若手交流リトリート
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] Remote support of optical microscope observation beyond 1000 km distance2021
- Author(s)
  Tsutsumi M, Kobayashi K, Nemoto T
- Organizer
  Global Bio Imaging -Exchange of Experience VI- online meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] 空間光位相変調器を用いた収差補正による生体組織深部の微細構造の可視化2021
- Author(s)
  山口和志、大友康平、小澤祐市、堤元佐、猪瀬朋子、平井健二、佐藤俊一、根本知己、雲林院宏
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] 蛍光イメージングの最新動向：より速く、より深く、より細かく、そしてより優しく2021
- Author(s)
  堤元佐
- Organizer
  琉球大学理学部海洋自然科学科生物系公開講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] 画像解析による超解像法SRRFのin vivoイメージングへの適用2021
- Author(s)
  堤元佐、髙橋泰伽、小林健太郎、根本知己
- Organizer
  第30回日本バイオイメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] Two-photon 3D live imaging of cellular ERK activation in multicellular tumor spheroid adhering gold nanostar for plasmonic photothermal effects2021
- Author(s)
  Kazushi Yamaguchi, Kohei Otomo, Yuichi Kozawa, Motosuke Tsutsumi, Tomoko Inose, Kenzi Hirai, Syunichi Sato, Tomomi Nemoto, Hiroshi Uji-i
- Organizer
  The 3rd Australia-Belgium-Japan joint symposium on excitonics and cellular communication
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] Application of novel image analysis method SRRF for deep and fast super resolution imaging2020
- Author(s)
  堤元佐、根本知己
- Organizer
  ExCELLS若手リトリート
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] SRRF-時空間蛍光相関超解像法　～画像解析による新規超解像顕微鏡～2020
- Author(s)
  堤元佐
- Organizer
  オックスフォード・インストゥルメンツ社 Andor ウェビナー第２回
- Invited
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] Application of novel image analysis method SRRF for deep and fast super resolution imaging2020
- Author(s)
  Tsutsumi M., Nemoto T
- Organizer
  ABiS International Symposium 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] Image analysis based super-resolution two-photon microscopy TP-SRRF for deep imaging2020
- Author(s)
  Motosuke Tsutsumi, Tomomi Nemoto
- Organizer
  第3回 ExCELLSシンポジウム
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] 多点走査型２光子顕微鏡によるAβオリゴマー曝露時のアストロサイトCa2+動態の可視化解析2020
- Author(s)
  中田開人、鎌田恭史、大友康平、石井宏和、堤元佐、榎木亮介、根本知己
- Organizer
  第29回日本バイオイメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] Application of novel image analysis method SRRF for deep and fast super resolution imaging2019
- Author(s)
  堤元佐、根本知己
- Organizer
  大学共同利用機関法人若手コロキウム
- Data Source
  KAKENHI-PROJECT-19K15406
[Presentation] 深部高速超解像イメージングのための新規画像解析法SRRFの適用検討2019
- Author(s)
  堤元佐、根本知己
- Organizer
  第２回ExCELLSシンポジウム
- Data Source
  KAKENHI-PROJECT-19K15406

1. 木村幸太郎 (20370116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 武石明佳 (30862007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 大友康平 (40547204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 高橋光規 (30788922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村田隆 (00242024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 藤田浩徳 (10552979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 伊藤俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsutsumi Motosuke 堤 元佐

Research Projects

Research Products

Co-Researchers

On the origin of polarized cell growth via analyses of tobacco culture cells and Closterium cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a novel deep 3D super-resolution observation method for living organisms by spatiotemporal fluorescence correlation analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自動追跡ロボット技術と超高速三次元イメージング技術の統合による脳動作原理の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Visualization of facilitated diffusion of transcription-factor by utilizing novel high-speed super-resolution microscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Multibeam continuous axial scanning two-photon microscopy for in vivo volumetric imaging in mouse brain2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fluorescence radial fluctuation enables two-photon super-resolution microscopy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Absorption, fluorescence, and two-photon excitation ability of 5-phenyl-13-arylisoindolo[2,1-a]quinolines prepared by one-pot reaction of ring-closing metathesis and 1,3-dipolar cycloaddition2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 3DeeCellTracker, a deep learning-based pipeline for segmenting and tracking cells in 3D time lapse images2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adaptive Optical Two-Photon Microscopy for Surface-Profiled Living Biological Specimens2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 時空間蛍光相関解析による２光子深部超解像イメージング2023

Author(s)

Organizer

Data Source

[Presentation] 時空間蛍光相関解析による生体深部超解像観察法の確立2023

Author(s)

Organizer

Data Source

[Presentation] 時空間蛍光相関解析による２光子深部超解像イメージング2023

Author(s)

Organizer

Data Source

[Presentation] Fluorescence Radial Fluctuation Enables Two-photon Super-Resolution Microscopy2023

Author(s)

Organizer

Data Source

[Presentation] Fluorescence Radial Fluctuation Enables Two-photon Super-Resolution Microscopy2023

Author(s)

Organizer

Data Source

[Presentation] "接着"を見る、視る、観る -蛍光顕微鏡技術の最前線-2022

Author(s)

Tsutsumi Motosuke 堤元佐

[Presentation] 光学顕微鏡の観察の新展開－光学分解能を超える観察とリモート観察－2022

[Presentation] SRRF-時空間蛍光相関超解像法　～画像解析による新規超解像顕微鏡～2020