Ishikawa Kosuke 石川耕資

… Alternative Names

ISHIKAWA Kosuke 石川耕資

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Researcher Number	60791374
Other IDs	https://orcid.org/0000-0002-6068-7276
Affiliation (Current)	2025: 北海道大学, 医学研究院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2025: 北海道大学, 医学研究院, 助教 2020 – 2022: 北海道大学, 大学病院, 助教 2019: 北海道大学, 医学研究院, 客員研究員 2018 – 2019: 北海道大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related Except Principal Investigator Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery
Keywords	Principal Investigator 脈管奇形 / 動静脈奇形 / 血管奇形 / 個別化医療 / 遺伝子変異 / 遺伝子診断 / リキッドバイオプシー / 遺伝子変異解析 / MAPKシグナル伝達経路 / PI3K/AKT/mTORシグナル伝達経路 … More / 静脈奇形 / Wound Bed Preparation / 再建 / 陰圧閉鎖療法 / NPWT / メカノバイオロジー / 悪性黒色腫 / 悪性腫瘍 / 局所陰圧閉鎖療法 / シロリムス / ラパマイシン / 硬化療法 / 血管内皮細胞 / 血管新生 … More Except Principal Investigator 間葉系幹細胞 / 低酸素応答 / リンパ浮腫 / マクロファージ / 創傷治癒 / マウス / 下肢慢性創傷 / HIF-1α / 機能的リンパ移植法 / 形成外科 / 頭蓋顎顔面 / 骨再生 / 抗老化 / エクソソーム / 光老化 / 皮膚 / HIF－1α / 繊維化抑制 / モノフォリノオリゴ修飾核酸 / レグネース１ / 急性期リンパ浮腫 / 続発性リンパ浮腫 / HIF-1 / 制御性T細胞 / 線維芽細胞 / ケロイド / 慢性創傷 / 大網・腸間膜 / 免疫・循環系 / 機能的リンパ節移植法 / natural helper T細胞 / milky spot / 大網・腸管膜 / 循環・免疫系 / 内臓脂肪 / 腫瘍免疫 / 移植リンパ節 / 悪性黒色種 / 機能的リンパ組織 / 組織培養・移植学 / lymph node transfer / 遊離リンパ節移植 / リンパ系再構築 / 血管柄付きリンパ節移植 Less

低侵襲な頭蓋顎顔面骨再法の開発：間葉系幹細胞とM2マクロファージによる細胞治療
- Principal Investigator
  
  三浦隆洋
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
続発性リンパ浮腫における急性期重症化を防ぐ！レグネース１を標的とした新たな治療法
- Principal Investigator
  
  佐藤千草
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
幹細胞によるM１/M２マクロファージ調整作用はリンパ浮腫線維化を抑制しうるか？
- Principal Investigator
  
  前田拓
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Restructuring of the lymphatic basin with HIF-1a stabilizers
- Principal Investigator
  
  草島英梨香
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Genetic diagnosis of vascular malformations by liquid biopsy and its application to precision medicinePrincipal Investigator
- Principal Investigator
  
  石川耕資
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
SASP Regulation of Photoaging - Skin Rejuvenation by Stem Cell Exosomes
- Principal Investigator
  
  高橋周子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Novel Treatment of Chronic Wounds of the Lower Extremity with Drugs Activating the Hypoxic Response System
- Principal Investigator
  
  Osawa Masayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Roles of the hypoxia response system in keloids: Normalization of local immunity and suppression of inflammation and fibrosis
- Principal Investigator
  
  Murao Naoki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Breakthrough in Oncoplastic Skin SurgeryPrincipal Investigator
- Principal Investigator
  
  Ishikawa Kosuke
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Potential abilities of visceral fat:circulation and immunity (hyper 2-way player)
- Principal Investigator
  
  Yamamoto Yuhei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Development of antiangiogenic therapy targeting mTOR signaling pathway for the treatment of complicated vascular malformationsPrincipal Investigator
- Principal Investigator
  
  ISHIKAWA Kosuke
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Hokkaido University
Development of functional lymph node transfer
- Principal Investigator
  
  YAMAMOTO Yuhei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Hokkaido University

All 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] 脈管異常の遺伝子異常2023
- Author(s)
  石川耕資, 佐々木了
- Journal Title
  
  皮膚科
  
  Volume: 4 Pages: 712-725
- Data Source
  KAKENHI-PROJECT-23K09072
[Journal Article] Therapeutic Potential of the Prolyl Hydroxylase Inhibitor Roxadustat in a Mouse Hindlimb Lymphedema Model2023
- Author(s)
  Yoshitada Hoshino, Masayuki Osawa, Emi Funayama, Kosuke Ishikawa, Takahiro Miura, Masahiro Hojo, Yuhei Yamamoto, Taku Maeda
- Journal Title
  
  Lymphatic Research and Biology
  
  Volume: - Issue: 4 Pages: 372-380
- DOI
  10.1089/lrb.2022.0071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09841
[Journal Article] Wound-healing problems associated with combined vascular malformations in Klippel-Trenaunay syndrome2019
- Author(s)
  Ishikawa Kosuke、Yamamoto Yuhei、Funayama Emi、Furukawa Hiroshi、Sasaki Satoru
- Journal Title
  
  Advances in Wound Care
  
  Volume: 8 Issue: 6 Pages: 246-255
- DOI
  10.1089/wound.2018.0835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16974
[Journal Article] Squamous cell carcinoma arising in a chronic leg ulcer in Klippel-Trenaunay syndrome after the Charles procedure: A case with 40 years of follow up2019
- Author(s)
  Ishikawa Kosuke、Funayama Emi、Yamamoto Yuhei、Furukawa Hiroshi、Hayashi Toshihiko、Murao Naoki、Osawa Masayuki、Maeda Taku、Fujita Munezumi、Sasaki Satoru
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 46 Issue: 11
- DOI
  10.1111/1346-8138.15001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16974
[Journal Article] Feasibility of pedicled vascularized inguinal lymph node transfer in a mouse model: A preliminary study2019
- Author(s)
  Ishikawa Kosuke、Maeda Taku、Funayama Emi、Hayashi Toshihiko、Murao Naoki、Osawa Masayuki、Furukawa Hiroshi、Oyama Akihiko、Yamamoto Yuhei
- Journal Title
  
  Microsurgery
  
  Volume: 39 Issue: 3 Pages: 247-254
- DOI
  10.1002/micr.30394
- NAID
  120006803951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05491
[Journal Article] Changes in high endothelial venules in lymph nodes after vascularized and nonvascularized lymph node transfer in a murine autograft model2019
- Author(s)
  Ishikawa Kosuke、Funayama Emi、Maeda Taku、Hayashi Toshihiko、Murao Naoki、Osawa Masayuki、Ito Riri、Furukawa Hiroshi、Oyama Akihiko、Yamamoto Yuhei
- Journal Title
  
  Journal of Surgical Oncology
  
  Volume: 119 Issue: 6 Pages: 700-707
- DOI
  10.1002/jso.25365
- NAID
  120006842186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05491
[Journal Article] 特集／患児・家族に寄り添う血管腫・脈管奇形の医療　混合型脈管奇形2019
- Author(s)
  佐々木了, 石川耕資
- Journal Title
  
  PEPARS
  
  Volume: 145 Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16974
[Presentation] マウス後肢リンパ浮腫モデルにおける創傷モデルの作成とHIF-1α活性調整薬剤の創傷治癒に与える影響2022
- Author(s)
  星野善允、前田拓、石川耕資、大澤昌之、舟山恵美、山本有平
- Organizer
  第103回北日本形成外科学会　北海道地方会
- Data Source
  KAKENHI-PROJECT-20K09841
[Presentation] マウス後肢リンパ浮腫モデルにおける創傷モデルの作成とHIF-1α活性調整薬剤の創傷に与える影響2022
- Author(s)
  星野善允、前田　拓、石川耕資、舟山恵美、大澤昌之、三浦隆洋、北條正洋、山本有平
- Organizer
  第103回北日本形成外科学会北海道地方会
- Data Source
  KAKENHI-PROJECT-20K09841
[Presentation] 新たなリンパ節移植動物モデルの開発－大網を用いて2021
- Author(s)
  北條正洋、前田拓、石川耕資、大澤昌之、舟山恵美、山本有平
- Organizer
  第30回日本形成外科学会基礎学術集会、東京、 2021.10.7-8
- Data Source
  KAKENHI-PROJECT-19H03811
[Presentation] マウス後肢リンパ浮腫モデルにおける創傷モデルの作成と低酸素応答因子・酸素環境の解析2021
- Author(s)
  星野善允、石川耕資、前田拓、大澤昌之、舟山恵美、山本有平
- Organizer
  第30回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20K09841
[Presentation] 顕微鏡下マウスリンパ節移植モデルの開発　新たな材料を求めて2021
- Author(s)
  北條正洋、前田拓、石川耕資、大澤昌之、舟山恵美、山本有平
- Organizer
  第48回日本マイクロサージャリー学会、つくば、2021.12.4
- Data Source
  KAKENHI-PROJECT-19H03811
[Presentation] リンパ系再構築における大網を用いた新たなマウスモデルの検証2021
- Author(s)
  3.北條正洋、前田拓、石川耕資、大澤昌之、舟山恵美、山本有平
- Organizer
  第42回北大形成外科アカデミー、札幌、2021.12.11
- Data Source
  KAKENHI-PROJECT-19H03811
[Presentation] 下肢Klippel-Trenaunay症候群に対する治療の検討2019
- Author(s)
  石川耕資, 藤田宗純, 竹田朋弘, 三田村真太郎, 舟山恵美, 佐々木了
- Organizer
  第16回日本血管腫血管奇形学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16974
[Presentation] PI3Kα阻害薬による静脈奇形とPROSの治療2019
- Author(s)
  石川耕資
- Organizer
  第62回日本形成外科学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16974
[Presentation] マウスリンパ節移植モデルにおける高内皮細静脈の組織学的検討～移植リンパ節への血流の有無による比較2019
- Author(s)
  石川耕資、前田　拓、舟山恵美、林　利彦、村尾尚規、大澤昌之、古川洋志、小山明彦、山本有平
- Organizer
  第43回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-16H05491
[Presentation] 上肢の過成長を伴う血管奇形症例の検討2019
- Author(s)
  石川耕資, 蕨雄大, 藤田宗純, 森山宇蘭, 舟山恵美, 山本有平, 佐々木了
- Organizer
  第62回日本手外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16974
[Presentation] 下肢Klippel-Trenaunay症候群における創傷の検討2019
- Author(s)
  石川耕資, 蕨雄大, 藤田宗純, 森山宇蘭, 竹田朋弘, 三田村真太郎, 舟山恵美, 佐々木了
- Organizer
  第11回日本創傷外科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K16974
[Presentation] マウス血管柄付きリンパ節移植モデルの確立と輸入リンパ管再疎通および移植リンパ節の組織学的検討2019
- Author(s)
  石川耕資、舟山恵美、林　利彦、村尾尚規、大澤昌之、前田　拓、古川洋志、小山明彦、山本有平
- Organizer
  第97回北日本形成外科学会北海道地方会
- Data Source
  KAKENHI-PROJECT-16H05491
[Presentation] マウス血管柄付きリンパ節移植モデルにおけるリンパ管再疎通および移植リンパ節の組織学的検討2018
- Author(s)
  石川耕資、舟山恵美、林　利彦、村尾尚規、大澤昌之、前田　拓、山本有平
- Organizer
  第27回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-16H05491
[Presentation] マウス血管柄付きリンパ節移植モデルにおける移植リンパ節に関する研究2018
- Author(s)
  石川耕資、舟山恵美、林　利彦、村尾尚規、大澤昌之、前田　拓、古川洋志、小山明彦、山本有平
- Organizer
  第37回北大形成外科アカデミー
- Data Source
  KAKENHI-PROJECT-16H05491
[Presentation] 機能的リンパ節移植に関する基礎研究2017
- Author(s)
  石川耕資，古川洋志，小山明彦，舟山恵美，林　利彦，村尾尚規，大澤昌之，前田　拓，山本有平
- Organizer
  第35回北大形成外科アカデミー
- Data Source
  KAKENHI-PROJECT-16H05491

1. 前田拓 (80813542)

# of Collaborated Projects: 10 results

# of Collaborated Products: 14 results
2. YAMAMOTO Yuhei (70271674)

# of Collaborated Projects: 7 results

# of Collaborated Products: 14 results
3. 舟山恵美 (10533630)

# of Collaborated Projects: 7 results

# of Collaborated Products: 14 results
4. 林利彦 (00432146)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
5. Murao Naoki (90706558)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
6. Osawa Masayuki (70625029)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
7. 古川洋志 (00399924)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
8. 小山明彦 (70374486)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. 三浦隆洋 (90829433)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 佐藤千草 (70893767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 松田識郁 (20975966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 草島英梨香 (30813547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 北條正洋 (80866666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 徐東經 (40975968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 高橋周子 (00829434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐々木雄輝 (00923369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ishikawa Kosuke 石川 耕資

ISHIKAWA Kosuke 石川 耕資

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Genetic diagnosis of vascular malformations by liquid biopsy and its application to precision medicinePrincipal Investigator

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Breakthrough in Oncoplastic Skin SurgeryPrincipal Investigator

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Development of antiangiogenic therapy targeting mTOR signaling pathway for the treatment of complicated vascular malformationsPrincipal Investigator

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[Journal Article] 脈管異常の遺伝子異常2023

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[Journal Article] Therapeutic Potential of the Prolyl Hydroxylase Inhibitor Roxadustat in a Mouse Hindlimb Lymphedema Model2023

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[Journal Article] Wound-healing problems associated with combined vascular malformations in Klippel-Trenaunay syndrome2019

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Ishikawa Kosuke 石川耕資

ISHIKAWA Kosuke 石川耕資

[Journal Article] 特集／患児・家族に寄り添う血管腫・脈管奇形の医療　混合型脈管奇形2019

[Presentation] 顕微鏡下マウスリンパ節移植モデルの開発　新たな材料を求めて2021