Masumura Yuki 増村雄喜

Researcher Number	60793437
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2020: 大阪大学, 医学系研究科, 招へい教員 2017 – 2018: 大阪大学, 医学系研究科, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 48040:Medical biochemistry-related / Cardiovascular medicine
Keywords	Principal Investigator カルシウム動態 / ヒトiPS細胞由来心筋細胞 / ハイコンテントイメージングシステム / ゲノム編集 / カルシウム / ハイコンテントイメージング / RNA degradation / 心不全 / Btg2 / RNA分解制御 … More / 心筋肥大関連因子 / イメージング解析 / 心筋肥大 / 次世代シークエンサー / RNA代謝 / 心肥大 Less

Elucidation of the molecular mechanism of genetic disorder in intractable cardiomyopathy using high-content imaging combined with genome editingPrincipal Investigator
- Principal Investigator
  
  Masumura Yuki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka University
Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradationPrincipal Investigator
- Principal Investigator
  
  Masumura Yuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University

All 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Adeno-associated virus-mediated gene delivery promotes S-phase entry-independent precise targeted integration in cardiomyocytes2020
- Author(s)
  Kohama Yasuaki、Higo Shuichiro、Masumura Yuki、Shiba Mikio、Kondo Takumi、Ishizu Takamaru、Higo Tomoaki、Nakamura Satoki、Kameda Satoshi、Tabata Tomoka、Inoue Hiroyuki、Motooka Daisuke、Okuzaki Daisuke、Takashima Seiji、Miyagawa Shigeru、Sawa Yoshiki、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15348-15348
- DOI
  10.1038/s41598-020-72216-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K08356, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-18K08069, KAKENHI-PROJECT-19K16518
[Journal Article] Old-Age Onset Progressive Cardiac Contractile Dysfunction in a Patient with Polycystic Kidney Disease Harboring a <i>PKD1</i> Frameshift Mutation2019
- Author(s)
  Suwa Yoshinobu、Higo Shuichiro、Nakamoto Kei、Sera Fusako、Kunimatsu Suzuka、Masumura Yuki、Kanzaki Machiko、Mizote Isamu、Mizuno Hiroya、Fujio Yasushi、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Int. Heart J.
  
  Volume: 60 Issue: 1 Pages: 220-225
- DOI
  10.1536/ihj.18-184
- NAID
  130007557187
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2019-01-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19543, KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18K15848, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-17K16004
[Journal Article] Targeted Genome Replacement via Homology-directed Repair in Non-dividing Cardiomyocytes2017
- Author(s)
  Ishizu T, Higo S, Masumura Y, Kohama Y, Shiba M, Higo T, Shibamoto M, Nakagawa A, Morimoto S, Takashima S, Hikoso S, Sakata Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 9363-9363
- DOI
  10.1038/s41598-017-09716-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08514, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-17K08540, KAKENHI-PROJECT-17K16004, KAKENHI-PROJECT-15H04820
[Presentation] ハイコンテントイメージング・数値計算ソフトウェアを用いた心筋症iPS 分化心筋におけるカルシウム動態解析2020
- Author(s)
  田端智香,肥後修一朗,増村雄喜,志波幹夫,小濱康明,近藤匠巳,亀田聡士,井上裕之,中村聡希,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第6回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-19K16518
[Presentation] Medical Application of Genome Editing for Advanced Heart Failure2019
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  第83回日本循環器学会学術集会　プレナリーセッション
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] High-content Image Analysis Combined with Targeted Gene Disruption Clarifies the Role for Pkd1 as a Sarcoplasmic Reticulum Protein that Regulates Calcium Influx in Cardiomyocytes2019
- Author(s)
  Yuki Masumura
- Organizer
  第3回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-19K16518
[Presentation] ゲノム編集の重症心不全医療応用2018
- Author(s)
  肥後修一朗、増村雄喜、彦惣俊吾、坂田泰史
- Organizer
  第22回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation2018
- Author(s)
  Yuki Masumura, Shuichiro Higo, Shungo Hikoso, Seiji Takashima, Yasushi Sakata
- Organizer
  第2回BCVR
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] Genome Editing in Cardiomyopathy2018
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  European Society of Cardiology Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] Evaluation of Calcium Handling Properties of Individual Cardiomyocytes using High-content Image Analysis2018
- Author(s)
  Yuki Masumura, Suzuka Kunimatsu, Shuichiro Higo, Takamaru Ishizu, Yasuaki Kohama, Mikio Shiba, Takumi Kondo, Tomoaki Higo, Masato Shibamoto, Seiji Takashima, Shungo Hikoso and Yasushi Sakata
- Organizer
  第1回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] ハイコンテントイメージ解析及びゲノム編集を用いた心筋症遺伝子変異の病原性の迅速な評価系の構築2018
- Author(s)
  増村雄喜、國松鈴花、肥後修一朗、小濱康明、志波幹夫、近藤匠巳、肥後友彰、柴本将人、高島成二、宮川繁、彦惣俊吾、坂田泰史
- Organizer
  第3回心筋症研究会 YIA
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] Therapeutic Genome Editing Targeting an Upstream Genetic Basis of Advanced Heart Failure2018
- Author(s)
  Shuichiro Higo, Takamaru Ishizu, Yuki Masumura, Tomoaki Higo, Shungo Hikoso, Yasushi Sakata
- Organizer
  第82回日本循環器学会学術集会　プレナリーセッション　心不全診療のfuturability
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] Rapid Evaluation of Candidate Causal Gene Mutation using High-content Image Analysis2018
- Author(s)
  Yuki Masumura, Suzuka Kunimatsu, Shuichiro Higo, Yasuaki Kohama, Mikio Shiba, Takumi Kondo, Masato Shibamoto, Seiji Takashima, Shigeru Miyagawa, Shungo Hikoso, Yasushi Sakata
- Organizer
  American Heart Association Scientific Sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] mRNA分解制御機構に関連した心筋細胞肥大メカニズムの解明2017
- Author(s)
  増村雄喜、肥後修一朗、高島成二、彦惣俊吾、坂田泰史
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K16004
[Presentation] Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation2017
- Author(s)
  増村雄喜、肥後修一朗、高島成二、彦惣俊吾、坂田泰史
- Organizer
  Cutting Edge Developments in RNA Biology for the Control of Gene Expression
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16004

1. TO Seikon

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 森本幸生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 彦惣俊吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 肥後修一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masumura Yuki 増村 雄喜

Research Projects

Research Products

Co-Researchers

Elucidation of the molecular mechanism of genetic disorder in intractable cardiomyopathy using high-content imaging combined with genome editingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Adeno-associated virus-mediated gene delivery promotes S-phase entry-independent precise targeted integration in cardiomyocytes2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Old-Age Onset Progressive Cardiac Contractile Dysfunction in a Patient with Polycystic Kidney Disease Harboring a <i>PKD1</i> Frameshift Mutation2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Targeted Genome Replacement via Homology-directed Repair in Non-dividing Cardiomyocytes2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] ハイコンテントイメージング・数値計算ソフトウェアを用いた心筋症iPS 分化心筋におけるカルシウム動態解析2020

Author(s)

Organizer

Data Source

[Presentation] Medical Application of Genome Editing for Advanced Heart Failure2019

Author(s)

Organizer

Data Source

[Presentation] High-content Image Analysis Combined with Targeted Gene Disruption Clarifies the Role for Pkd1 as a Sarcoplasmic Reticulum Protein that Regulates Calcium Influx in Cardiomyocytes2019

Author(s)

Organizer

Data Source

[Presentation] ゲノム編集の重症心不全医療応用2018

Author(s)

Organizer

Data Source

[Presentation] Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation2018

Author(s)

Organizer

Data Source

[Presentation] Genome Editing in Cardiomyopathy2018

Author(s)

Organizer

Data Source

[Presentation] Evaluation of Calcium Handling Properties of Individual Cardiomyocytes using High-content Image Analysis2018

Author(s)

Organizer

Data Source

[Presentation] ハイコンテントイメージ解析及び ゲノム編集を用いた心筋症遺伝子変異の病原性の迅速な評価系の構築2018

Author(s)

Organizer

Data Source

[Presentation] Therapeutic Genome Editing Targeting an Upstream Genetic Basis of Advanced Heart Failure2018

Author(s)

Organizer

Data Source

[Presentation] Rapid Evaluation of Candidate Causal Gene Mutation using High-content Image Analysis2018

Author(s)

Organizer

Data Source

[Presentation] mRNA分解制御機構に関連した心筋細胞肥大メカニズムの解明2017

Author(s)

Organizer

Data Source

[Presentation] Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation2017

Masumura Yuki 増村雄喜

[Presentation] ハイコンテントイメージ解析及びゲノム編集を用いた心筋症遺伝子変異の病原性の迅速な評価系の構築2018