Kawasoe Yoshitaka 河添好孝

Researcher Number	60805422
Other IDs
Affiliation (Current)	2025: 九州大学, 理学研究院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 九州大学, 理学研究院, 助教 2019 – 2020: 九州大学, 理学研究院, 特任助教 2017 – 2018: 九州大学, 理学研究院, 学術研究員
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Molecular biology
Keywords	Principal Investigator ツメガエル卵抽出液 / ミスマッチ修復 / 試験管内再構成 / 一本鎖アニーリング / 相同組換え / PCNAアンローディング / クランプローダー / DNA複製 / PCNA / Homology-directed repair … More / DNA二重鎖切断修復 / DNA二重鎖切断損傷 / DNA修復 / アンローディング / クランプローダー複合体 Less

試験管内再構成による相同組換えの正確性制御機構の理解Principal Investigator
- Principal Investigator
  
  河添好孝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kyushu University
Elucidation of mechanisms that control the fidelity of homologous recombination using in vitro analysesPrincipal Investigator
- Principal Investigator
  
  Kawasoe Yoshitaka
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kyushu University
Elucidation of regulations of PCNA dynamics by the mismatch repair systemPrincipal Investigator
- Principal Investigator
  
  Kawasoe Yoshitaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kyushu University
Elucidation of mechanisms that the eukaryotic mismatch repair system regulates PCNA unloadingPrincipal Investigator
- Principal Investigator
  
  Kawasoe Yoshitaka
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts2024
- Author(s)
  Tatsukawa Kensuke、Sakamoto Reihi、Kawasoe Yoshitaka、Kubota Yumiko、Tsurimoto Toshiki、Takahashi Tatsuro S.、Ohashi Eiji
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 52 Issue: 6 Pages: 3146-3163
- DOI
  10.1093/nar/gkae082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15036, KAKENHI-PUBLICLY-22H04697, KAKENHI-PROJECT-20H03186
[Journal Article] The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in Xenopus egg extracts2024
- Author(s)
  Kawasoe Yoshitaka、Shimokawa Sakiko、Gillespie Peter J.、Blow J. Julian、Tsurimoto Toshiki、Takahashi Tatsuro S.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 1 Pages: 105588-105588
- DOI
  10.1016/j.jbc.2023.105588
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15036, KAKENHI-PUBLICLY-22H04697, KAKENHI-PROJECT-20H03186
[Journal Article] The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD52023
- Author(s)
  Miyashita Ryota、Nishiyama Atsuya、Qin Weihua、Chiba Yoshie、Kori Satomi、Kato Norie、Konishi Chieko、Kumamoto Soichiro、Kozuka-Hata Hiroko、Oyama Masaaki、Kawasoe Yoshitaka、Tsurimoto Toshiki、Takahashi Tatsuro S、Leonhardt Heinrich、Arita Kyohei、Nakanishi Makoto
- Journal Title
  
  eLife
  
  Volume: 12 Pages: 79013-79013
- DOI
  10.7554/elife.79013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15036, KAKENHI-PLANNED-21H05280, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-20H03186, KAKENHI-ORGANIZER-19H05739, KAKENHI-PUBLICLY-21H00272, KAKENHI-PUBLICLY-22H04697
[Journal Article] Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication2021
- Author(s)
  Jones Mathew J.K.、Gelot Camille、Munk Stephanie、Koren Amnon、Kawasoe Yoshitaka、George Kelly A.、Santos Ruth E.、Olsen Jesper V.、McCarroll Steven A.、Frattini Mark G.、Takahashi Tatsuro S.、Jallepalli Prasad V.
- Journal Title
  
  Molecular Cell
  
  Volume: 81 Issue: 3 Pages: 426-441.e8
- DOI
  10.1016/j.molcel.2021.01.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21399, KAKENHI-PUBLICLY-20H05392, KAKENHI-PROJECT-20H03186, KAKENHI-PROJECT-19K16042
[Journal Article] Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1.2018
- Author(s)
  Terui R, Nagao K, Kawasoe Y, Taki K, Higashi TL, Tanaka S, Nakagawa T, Obuse C, Masukata H, Takahashi TS
- Journal Title
  
  Genes & development
  
  Volume: 32(11-12) Issue: 11-12 Pages: 806-821
- DOI
  10.1101/gad.310995.117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21761, KAKENHI-ORGANIZER-15H05970, KAKENHI-PLANNED-17H06426, KAKENHI-PUBLICLY-18H04713, KAKENHI-PUBLICLY-18H04716, KAKENHI-PLANNED-18H05532, KAKENHI-PROJECT-16H04739, KAKENHI-PROJECT-17H01876, KAKENHI-PROJECT-17H06935, KAKENHI-PROJECT-15K14450, KAKENHI-PROJECT-18K06060
[Journal Article] Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway.2017
- Author(s)
  Kato N, Kawasoe Y, Williams H, Coates E, Roy U, Shi Y, Beese LS, Scharer OD, Yan H, Gottesman ME, Takahashi TS, Gautier J.
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 5 Pages: 1375-1385
- DOI
  10.1016/j.celrep.2017.10.032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01876, KAKENHI-PROJECT-17H06935, KAKENHI-PROJECT-16K14671
[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2023
- Author(s)
  河添　好孝
- Organizer
  第27回 DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-22K15036
[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2022
- Author(s)
  河添好孝
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K15036
[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2022
- Author(s)
  河添好孝
- Organizer
  第95回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K15036
[Presentation] クロマチンを基質としたミスマッチ修復反応の試験管内再構成に向けた解析2021
- Author(s)
  福田翔太、河添好孝、高橋達郎
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16042
[Presentation] WRNヘリカーゼはDNA二重鎖切断修復の正確性維持に重要である2021
- Author(s)
  河添好孝
- Organizer
  第38回染色体ワークショップ・第19回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-19K16042
[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2021
- Author(s)
  河添好孝、織田里美、坂詰彩、久持涼子、高橋達郎
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-19K16042
[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2021
- Author(s)
  河添好孝、織田里美、坂詰彩、久持涼子、高橋達郎
- Organizer
  第26回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-19K16042
[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼはDNA二重鎖切断修復の正確性を制御する2021
- Author(s)
  河添好孝、坂詰彩、織田里美、高橋達郎
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16042
[Presentation] ツメガエル卵抽出液におけるPCNAアンローディングは主にElg1-RFCが担う2019
- Author(s)
  河添　好孝
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16042
[Presentation] The Elg1-Rfc2-5 complex (Elg1-RFC) is the major PCNA-unloading complex in Xenopus egg extracts2018
- Author(s)
  Yoshitaka Kawasoe、Sakiko Shimokawa、Toshiki Tsurimoto、Tatsuro Takahashi
- Organizer
  OKAZAKI Fragment Memorial Symposium: Celebrating the 50th anniversary of the discontinuous DNA replication model
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06935
[Presentation] Elg1-Rfc2-5複合体（Elg1-RFC）はツメガエル卵抽出液における主たるPCNAアンローディング複合体である2018
- Author(s)
  河添好孝、下川紗貴子、釣本敏樹、高橋達郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H06935
[Presentation] ミスマッチ修復経路に依存した抗組換え反応の試験管内再現による解析2017
- Author(s)
  織田里美、河添好孝、坂詰彩、中川拓郎、升方久夫、高橋達郎
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H06935

1. TAKAHASHI Tatsuro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kawasoe Yoshitaka 河添 好孝

Research Projects

Research Products

Co-Researchers

試験管内再構成による相同組換えの正確性制御機構の理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanisms that control the fidelity of homologous recombination using in vitro analysesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of regulations of PCNA dynamics by the mismatch repair systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanisms that the eukaryotic mismatch repair system regulates PCNA unloadingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in Xenopus egg extracts2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD52023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2023

Author(s)

Organizer

Data Source

[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2022

Author(s)

Organizer

Data Source

[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2022

Author(s)

Organizer

Data Source

[Presentation] クロマチンを基質としたミスマッチ修復反応の試験管内再構成に向けた解析2021

Author(s)

Organizer

Data Source

[Presentation] WRNヘリカーゼはDNA二重鎖切断修復の正確性維持に重要である2021

Author(s)

Organizer

Data Source

[Presentation] WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する2021

Author(s)

Kawasoe Yoshitaka 河添好孝