Shimomura Osamu 下村治

… Alternative Names

Osamu Shimomura 下村治

Less

Researcher Number	60808070
Other IDs
Affiliation (Current)	2023: 筑波大学, 医学医療系, 講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 筑波大学, 医学医療系, 講師
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Medium-sized Section 50:Oncology and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator レクチン / 糖鎖 / 膵癌 / 糖タンパク / 早期診断 / 膵臓がん / Liquid biopsy / 循環腫瘍細胞 / 神経叢浸潤 / 分子標的治療 … More / 光感受性レクチン融合薬 / 新規膵癌治療 / 光免疫療法 / 早期診断法 / ELISA / 膵臓癌 … More Except Principal Investigator レクチン / 標的治療 / 糖鎖 / 膵がん / １細胞解析 / 膵がん幹細胞 / 糖鎖マーカー / 膵液瘻 / 閉鎖陰圧療法 / 糖鎖ーレクチン / 光免疫治療 / リキッドバイオプシー / 胃癌 / 胃癌ゲノム型 / レクチン薬物複合体 / rBC2 / バイオマーカー / ゲノム / スキルス胃癌 / rBC2LC-N / がん標的治療 / 薬剤融合タンパク / がん特異的糖鎖 / 癌標的治療 / 膵癌 / 緑膿菌外毒素(PE38) / 糖鎖標的治療 Less

血中循環腫瘍細胞をレクチンで捕獲する新規回収法と診断技術の開発Principal Investigator
- Principal Investigator
  
  下村治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Tsukuba
糖鎖―レクチン反応と光免疫療法の融合による新規癌治療
- Principal Investigator
  
  小田竜也
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Tsukuba
膵液瘻予防を目的とした閉鎖陰圧療法の開発
- Principal Investigator
  
  久倉勝治
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Tsukuba
Discovery of glycan markers of pancreatic cancer stem cells by single-cell glycomics
- Principal Investigator
  
  舘野浩章
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
ポストゲノム解析：糖結合レクチンによる胃癌プロファイリングと新規診断、治療法探索
- Principal Investigator
  
  明石義正
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Tsukuba
A novel UV-controlled cancer therapy using lectin-doxorubicin prodrug conjugate targeting pancreatic cancer glycansPrincipal Investigator
- Principal Investigator
  
  Shimomura Osamu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Tsukuba
The detection of early stage pancreatic cancer with sandwich ELISA using tumor specific lectinsPrincipal Investigator
- Principal Investigator
  
  Osamu Shimomura
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Tsukuba
Novel cancer therapy strategies, targeting cancer cell surface glycans using lectins (=glycan binding protein) as drug carriers.
- Principal Investigator
  
  ODA Tatsuya
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  University of Tsukuba
Sandwich ELISA assay using antibody and lectin for early detection of pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  下村治
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba

All 2022 2020 2019 2018

All Journal Article Presentation

[Journal Article] Lectin drug conjugate therapy for colorectal cancer2020
- Author(s)
  Kitaguchi Daichi、Oda Tatsuya、Enomoto Tsuyoshi、Ohara Yusuke、Owada Yohei、Akashi Yoshimasa、Furuta Tomoaki、Yu Yang、Kimura Sota、Kuroda Yukihito、Kurimori Ko、Miyazaki Yoshihiro、Furuya Kinji、Shimomura Osamu、Tateno Hiroaki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 12 Pages: 4548-4557
- DOI
  10.1111/cas.14687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09097, KAKENHI-PROJECT-20K16404, KAKENHI-PROJECT-18K16340, KAKENHI-PROJECT-19K18078
[Journal Article] Retrocolic Gastrojejunostomy After Pancreaticoduodenectomy: A Satisfactory Delayed Gastric-Emptying Rate.2019
- Author(s)
  Miyazaki Y1, Oda T, Shimomura O, Enomoto T, Akashi Y, Hisakura K, Ohara Y, Kimura S, Hashimoto S, Ohkohchi N.
- Journal Title
  
  Pancreas.
  
  Volume: 48 Issue: 4 Pages: 579-584
- DOI
  10.1097/mpa.0000000000001295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04057
[Journal Article] Indocyanine green fluorescence-navigated laparoscopic metastasectomy for peritoneal metastasis of hepatocellular carcinoma: a case report.2018
- Author(s)
  Miyazaki Y1, Kurata M2, Oshiro Y1, Shimomura O1, Takahashi K1, Oda T1, Ohkohchi N1.
- Journal Title
  
  Surg Case Rep.
  
  Volume: 4 Issue: 1 Pages: 130-133
- DOI
  10.1186/s40792-018-0537-x
- NAID
  120007128329
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04057
[Journal Article] Surgical resection of hepatic and rectal metastases of pancreatic acinar cell carcinoma (PACC): a case report.2018
- Author(s)
  Ohara Y, Oda T, Enomoto T, Hisakura K, Akashi Y, Ogawa K, Owada Y, Domoto Y, Miyazaki Y, Shimomura O, Kurata M, Ohkohchi N.
- Journal Title
  
  World J Surg Oncol
  
  Volume: 16 Issue: 1 Pages: 1457-8
- DOI
  10.1186/s12957-018-1457-8
- NAID
  120007133820
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16340, KAKENHI-PROJECT-18H04057
[Presentation] Glycan expression profile of signet gastric cancer and potential applicability of lectin drug conjugate2022
- Author(s)
  Yoshimsa Akashi, Yu Yang, Osamu Shimomura, Yoshihiro Miyazaki, Tatsuya Oda, et al.
- Organizer
  第94回日本胃癌学会
- Data Source
  KAKENHI-PROJECT-20K09097
[Presentation] A novel UV-controlled cancer therapy using lectin-doxorubicin prodrug conjugate targetingpancreatic cancer glycans2020
- Author(s)
  Yukihito Kuroda, Osamu Shimomura, Fumi Minoshima, Hiroaki Tateno, Tatsuya Oda
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-20K17638
[Presentation] 結合タンパク「レクチン」を用いた新規膵癌標的治療法の開発2018
- Author(s)
  下村治; 小田竜也; 舘野浩章; 木村聡大; 宮崎貴寛; 小澤佑輔、大河内信弘、
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-18H04057
[Presentation] レクチン薬剤複合体を用いた膵癌細胞表面糖鎖をターゲットにした新規癌治療【Molecular Cancer Therapeutics】2018
- Author(s)
  下村治; 小田竜也; 舘野浩章; 小澤佑介; 木村聡大; 坂下信悟、野口雅之、大河内信弘
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H04057

1. ODA Tatsuya (20282353)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. 明石義正 (50709722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 久倉勝治 (60550168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 橋本真治 (60624666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 宮崎貴寛 (90909433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 舘野浩章 (30450670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 松阪諭 (00372665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shimomura Osamu 下村 治

Osamu Shimomura 下村 治

Research Projects

Research Products

Co-Researchers

血中循環腫瘍細胞をレクチンで捕獲する新規回収法と診断技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖鎖―レクチン反応と光免疫療法の融合による新規癌治療

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

膵液瘻予防を目的とした閉鎖陰圧療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovery of glycan markers of pancreatic cancer stem cells by single-cell glycomics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ポストゲノム解析：糖結合レクチンによる胃癌プロファイリングと新規診断、治療法探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel UV-controlled cancer therapy using lectin-doxorubicin prodrug conjugate targeting pancreatic cancer glycansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The detection of early stage pancreatic cancer with sandwich ELISA using tumor specific lectinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel cancer therapy strategies, targeting cancer cell surface glycans using lectins (=glycan binding protein) as drug carriers.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Sandwich ELISA assay using antibody and lectin for early detection of pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Lectin drug conjugate therapy for colorectal cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retrocolic Gastrojejunostomy After Pancreaticoduodenectomy: A Satisfactory Delayed Gastric-Emptying Rate.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Indocyanine green fluorescence-navigated laparoscopic metastasectomy for peritoneal metastasis of hepatocellular carcinoma: a case report.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Surgical resection of hepatic and rectal metastases of pancreatic acinar cell carcinoma (PACC): a case report.2018

Author(s)

Journal Title

DOI

NAID

Shimomura Osamu 下村治

Osamu Shimomura 下村治