Sotokawauchi Ami 外川内亜美

Researcher Number	60809177
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 研究補助員
Affiliation (based on the past Project Information) *help	2023 – 2024: 久留米大学, 医学部, 研究補助員 2019 – 2021: 久留米大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related Except Principal Investigator Basic Section 53040:Nephrology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 42040:Laboratory animal science-related
Keywords	Principal Investigator RAGE / アプタマー / 終末糖化産物 / 骨粗鬆症 / 糖尿病 / AGE / DNAアプタマー / 2型糖尿病 / 終末糖化産物受容体 Except Principal Investigator RAGE … More / アプタマー / 糖尿病性腎症 / 糖尿病腎症 / 核酸医薬 / RAGEアプタマー / NEC / 壊死性腸炎 / 急性腎障害 / 敗血症 / 動脈硬化症 / 核酸医薬品 / 終末糖化産物 / 動脈硬化 Less

Aptamer Raised Against Receptor for Advanced Glycation End Products (RAGE) Improves Survival Rate in Septic Acute Kidney Injury Mice
- Principal Investigator
  
  倉八朋宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kurume University
AGE－RAGE系を標的とした骨粗鬆症の新規治療法の開発Principal Investigator
- Principal Investigator
  
  外川内亜美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kurume University
Development of an Innovative Therapy Utilizing RAGE Aptamer to Achieve Zero Mortality in Neonatal Necrotizing Enterocolitis.
- Principal Investigator
  
  古賀義法
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
Development of a novel therapeutic approach for diabetic nephropathy by nucleic acid medicine (DNA aptamer).
- Principal Investigator
  
  松井孝憲
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fukui Prefectural University
Identification of structures of advanced glycation end-products responsible for proatherosclerotic effects - analysis using aptamers.
- Principal Investigator
  
  Matsui Takanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kurume University
Regulation of Cardiovascular and Metabolic Diseases by RAGE-Aptamer - Study in Animal ModelsPrincipal Investigator
- Principal Investigator
  
  Sotokawauchi Ami
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kurume University

All 2023 2021

All Journal Article Presentation

[Journal Article] DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice2021
- Author(s)
  Koga Yoshinori、Sotokawauchi Ami、Higashimoto Yuichiro、Nishino Yuri、Hashizume Naoki、Kakuma Tatsuyuki、Akiba Jun、Tanaka Yoshiaki、Matsui Takanori、Yagi Minoru、Yamagishi Sho-ichi
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2021 Issue: 1 Pages: 1-20
- DOI
  10.1155/2021/9932311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574, KAKENHI-PROJECT-19K09086
[Journal Article] DNA aptamer raised against receptor for advanced glycation end products suppresses renal tubular damage and improves insulin resistance in diabetic mice2021
- Author(s)
  Sotokawauchi Ami、Matsui Takanori、Higashimoto Yuichiro、Nishino Yuri、Koga Yoshinori、Yagi Minoru、Yamagishi Sho-ichi
- Journal Title
  
  Diabetes and Vascular Disease Research
  
  Volume: 18 Issue: 1 Pages: 1-8
- DOI
  10.1177/1479164121990533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16387, KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574
[Journal Article] Pigment epithelium?derived factor inhibits advanced glycation end product?induced proliferation, VEGF and MMP?9 expression in breast cancer cells via interaction with laminin receptor2021
- Author(s)
  Tsuruhisa Shiori、Matsui Takanori、Koga Yoshinori、Sotokawauchi Ami、Yagi Minoru、Yamagishi Sho-Ichi
- Journal Title
  
  Oncology Letters
  
  Volume: 22 Issue: 2 Pages: 1-9
- DOI
  10.3892/ol.2021.12890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574
[Presentation] 終末糖化産物受容体を阻害するDNA アプタマーはLPS 誘導性敗血症マウスの生存率を改善する2023
- Author(s)
  外川内亜美，古賀義法，東元祐一郎，西野友梨，松井孝憲，山岸昌一
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K14447
[Presentation] DNAアプタマーによるAGE－RAGE系の阻害は老年疾患を包括的に抑制する2021
- Author(s)
  外川内亜美、東元　祐一郎、古賀　義法、松井孝憲、山岸昌一
- Organizer
  8)第32回脳心血管抗加齢研究会第17回学術大会・日本抗加齢協会第5回学術フォーラム
- Data Source
  KAKENHI-PROJECT-19K06461
[Presentation] 終末糖化産物受容体の阻害は2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021
- Author(s)
  外川内亜美，松井孝憲，西野友梨，東元祐一郎，山岸昌一
- Organizer
  第21回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-19K16387
[Presentation] 終末糖化産物受容体RAGEを阻害するDNAアプタマーは，2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021
- Author(s)
  外川内亜美、松井孝憲、西野友梨、東元祐一郎、山岸昌一
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K06461
[Presentation] 終末糖化産物受容体RAGEを阻害するDNAアプタマーは，2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021
- Author(s)
  外川内亜美，松井孝憲，西野友梨，東元祐一郎，山岸昌一
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K16387
[Presentation] 内皮細胞におけるグリセルアルデヒド由来AGEsのRAGEを介した炎症作用は DNAアプタマーにより抑制しうる2021
- Author(s)
  松井孝憲、外川内亜美、東元祐一郎、山岸昌一
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K06461

1. Matsui Takanori (10425233)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. 古賀義法 (70569433)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 東元祐一郎 (40352124)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 山岸昌一 (40281026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 加治建 (50315420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 倉八朋宏 (80895053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 升井大介 (90624495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 家入里志 (00363359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大西峻 (10614638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 川野孝文 (40457651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 杉田光士郎 (50781514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 武藤充 (70404522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中目和彦 (70448570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 東舘成希 (70725613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sotokawauchi Ami 外川内 亜美

Research Projects

Research Products

Co-Researchers

Aptamer Raised Against Receptor for Advanced Glycation End Products (RAGE) Improves Survival Rate in Septic Acute Kidney Injury Mice

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

AGE－RAGE系を標的とした骨粗鬆症の新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of an Innovative Therapy Utilizing RAGE Aptamer to Achieve Zero Mortality in Neonatal Necrotizing Enterocolitis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel therapeutic approach for diabetic nephropathy by nucleic acid medicine (DNA aptamer).

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of structures of advanced glycation end-products responsible for proatherosclerotic effects - analysis using aptamers.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of Cardiovascular and Metabolic Diseases by RAGE-Aptamer - Study in Animal ModelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA aptamer raised against receptor for advanced glycation end products suppresses renal tubular damage and improves insulin resistance in diabetic mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pigment epithelium?derived factor inhibits advanced glycation end product?induced proliferation, VEGF and MMP?9 expression in breast cancer cells via interaction with laminin receptor2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 終末糖化産物受容体を阻害するDNA アプタマーはLPS 誘導性敗血症マウスの生存率を改善する2023

Author(s)

Organizer

Data Source

[Presentation] DNAアプタマーによるAGE－RAGE系の阻害は老年疾患を包括的に抑制する2021

Author(s)

Organizer

Data Source

[Presentation] 終末糖化産物受容体の阻害は2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021

Author(s)

Organizer

Data Source

[Presentation] 終末糖化産物受容体RAGEを阻害するDNAアプタマーは，2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021

Author(s)

Organizer

Data Source

[Presentation] 終末糖化産物受容体RAGEを阻害するDNAアプタマーは，2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021

Author(s)

Organizer

Data Source

[Presentation] 内皮細胞におけるグリセルアルデヒド由来AGEsのRAGEを介した炎症作用は DNAアプタマーにより抑制しうる2021

Author(s)

Organizer

Data Source

Sotokawauchi Ami 外川内亜美