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Sotokawauchi Ami  外川内 亜美

ORCIDConnect your ORCID iD *help
Researcher Number 60809177
Other IDs
Affiliation (Current) 2025: 久留米大学, 医学部, 研究補助員
Affiliation (based on the past Project Information) *help 2023 – 2024: 久留米大学, 医学部, 研究補助員
2019 – 2021: 久留米大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related
Except Principal Investigator
Basic Section 53040:Nephrology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 42040:Laboratory animal science-related
Keywords
Principal Investigator
RAGE / アプタマー / 終末糖化産物 / 骨粗鬆症 / 糖尿病 / AGE / DNAアプタマー / 2型糖尿病 / 終末糖化産物受容体
Except Principal Investigator
RAGE … More / アプタマー / 糖尿病性腎症 / 糖尿病腎症 / 核酸医薬 / RAGEアプタマー / NEC / 壊死性腸炎 / 急性腎障害 / 敗血症 / 動脈硬化症 / 核酸医薬品 / 終末糖化産物 / 動脈硬化 Less
  • Research Projects

    (6 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (14 People)
  •  Aptamer Raised Against Receptor for Advanced Glycation End Products (RAGE) Improves Survival Rate in Septic Acute Kidney Injury Mice

    • Principal Investigator
      倉八 朋宏
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kurume University
  •  AGE-RAGE系を標的とした骨粗鬆症の新規治療法の開発Principal Investigator

    • Principal Investigator
      外川内 亜美
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kurume University
  •  Development of an Innovative Therapy Utilizing RAGE Aptamer to Achieve Zero Mortality in Neonatal Necrotizing Enterocolitis.

    • Principal Investigator
      古賀 義法
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kurume University
  •  Development of a novel therapeutic approach for diabetic nephropathy by nucleic acid medicine (DNA aptamer).

    • Principal Investigator
      松井 孝憲
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Fukui Prefectural University
  •  Identification of structures of advanced glycation end-products responsible for proatherosclerotic effects - analysis using aptamers.

    • Principal Investigator
      Matsui Takanori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Kurume University
  •  Regulation of Cardiovascular and Metabolic Diseases by RAGE-Aptamer - Study in Animal ModelsPrincipal Investigator

    • Principal Investigator
      Sotokawauchi Ami
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kurume University

All 2023 2021

All Journal Article Presentation

  • [Journal Article] DNA-Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice2021

    • Author(s)
      Koga Yoshinori、Sotokawauchi Ami、Higashimoto Yuichiro、Nishino Yuri、Hashizume Naoki、Kakuma Tatsuyuki、Akiba Jun、Tanaka Yoshiaki、Matsui Takanori、Yagi Minoru、Yamagishi Sho-ichi
    • Journal Title

      Oxidative Medicine and Cellular Longevity

      Volume: 2021 Issue: 1 Pages: 1-20

    • DOI

      10.1155/2021/9932311

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574, KAKENHI-PROJECT-19K09086
  • [Journal Article] DNA aptamer raised against receptor for advanced glycation end products suppresses renal tubular damage and improves insulin resistance in diabetic mice2021

    • Author(s)
      Sotokawauchi Ami、Matsui Takanori、Higashimoto Yuichiro、Nishino Yuri、Koga Yoshinori、Yagi Minoru、Yamagishi Sho-ichi
    • Journal Title

      Diabetes and Vascular Disease Research

      Volume: 18 Issue: 1 Pages: 1-8

    • DOI

      10.1177/1479164121990533

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16387, KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574
  • [Journal Article] Pigment epithelium?derived factor inhibits advanced glycation end product?induced proliferation, VEGF and MMP?9 expression in breast cancer cells via interaction with laminin receptor2021

    • Author(s)
      Tsuruhisa Shiori、Matsui Takanori、Koga Yoshinori、Sotokawauchi Ami、Yagi Minoru、Yamagishi Sho-Ichi
    • Journal Title

      Oncology Letters

      Volume: 22 Issue: 2 Pages: 1-9

    • DOI

      10.3892/ol.2021.12890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06461, KAKENHI-PROJECT-19K06574
  • [Presentation] 終末糖化産物受容体を阻害するDNA アプタマーはLPS 誘導性敗血症マウスの生存率を改善する2023

    • Author(s)
      外川内亜美,古賀義法,東元祐一郎,西野友梨,松井孝憲,山岸昌一
    • Organizer
      第66回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-23K14447
  • [Presentation] DNAアプタマーによるAGE-RAGE系の阻害は老年疾患を包括的に抑制する2021

    • Author(s)
      外川内 亜美、東元 祐一郎、古賀 義法、松井 孝憲、山岸 昌一
    • Organizer
      8)第32回脳心血管抗加齢研究会第17回学術大会・日本抗加齢協会第5回学術フォーラム
    • Data Source
      KAKENHI-PROJECT-19K06461
  • [Presentation] 終末糖化産物受容体の阻害は2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021

    • Author(s)
      外川内亜美,松井孝憲,西野友梨,東元祐一郎,山岸昌一
    • Organizer
      第21回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-19K16387
  • [Presentation] 終末糖化産物受容体RAGEを阻害するDNAアプタマーは,2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021

    • Author(s)
      外川内亜美、松井孝憲、西野友梨、東元祐一郎、山岸昌一
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K06461
  • [Presentation] 終末糖化産物受容体RAGEを阻害するDNAアプタマーは,2型糖尿病マウスのインスリン抵抗性および腎尿細管障害を改善する2021

    • Author(s)
      外川内亜美,松井孝憲,西野友梨,東元祐一郎,山岸昌一
    • Organizer
      第64回 日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K16387
  • [Presentation] 内皮細胞におけるグリセルアルデヒド由来AGEsのRAGEを介した炎症作用は DNAアプタマーにより抑制しうる2021

    • Author(s)
      松井孝憲、外川内亜美、東元祐一郎、山岸昌一
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K06461
  • 1.  Matsui Takanori (10425233)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 2.  古賀 義法 (70569433)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  東元 祐一郎 (40352124)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  山岸 昌一 (40281026)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  加治 建 (50315420)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  倉八 朋宏 (80895053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  升井 大介 (90624495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  家入 里志 (00363359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  大西 峻 (10614638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  川野 孝文 (40457651)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  杉田 光士郎 (50781514)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  武藤 充 (70404522)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  中目 和彦 (70448570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  東舘 成希 (70725613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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