nishiyama kazuhiro 西山和宏

… Alternative Names

Nishiyama Kazuhiro 西山和宏

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Researcher Number	60810116
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院獣医学研究科 , 准教授
Affiliation (based on the past Project Information) *help	2024: 大阪公立大学, (連合)獣医学研究科, 准教授 2023 – 2024: 大阪公立大学, 大学院獣医学研究科, 准教授 2020 – 2022: 九州大学, 薬学研究院, 講師 2018 – 2019: 九州大学, 薬学研究院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Transformative Research Areas, Section (III) / Complex systems Except Principal Investigator Pharmacology in pharmacy
Keywords	Principal Investigator 超硫黄分子 / TRPC6 / SqrR / 亜鉛 / GPCR / 亜鉛イオン / 腸心連関 / 超硫黄 / 腸管恒常性 / 筋萎縮 … More / タンパク質間相互作用 / NOX2 / TRPC3 / プリン受容体 / 慢性炎症 / inflammation / プリン作動性受容体 … More Except Principal Investigator 心血管病 / 受容体 / メカノセンサー / 運動療法 / 線維化 / 循環器学 / 情報伝達 / 運動 / 循環器 / シグナル伝達 / 膜タンパク質 / 薬学 / 薬理学 / 心血管疾患 / P2Y6R / TRPC / 運動模倣薬 / メカノバイオロジー / 活性酸素 / 心血管 / イオンチャネル Less

超硫黄分子センサータンパクを利用した新規超硫黄分子プローブの開発Principal Investigator
- Principal Investigator
  
  西山和宏
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Osaka Metropolitan University
腸内細菌叢で産生される超硫黄分子の生体における役割の解明Principal Investigator
- Principal Investigator
  
  西山和宏
- Project Period (FY)
  2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Metropolitan University
超硫黄を介したシグナル伝達を基軸とした腸心連関の解明Principal Investigator
- Principal Investigator
  
  西山和宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Metropolitan University
  Kyushu University
亜鉛イオンによるGPCR-Gタンパク質共役調節機構の解明Principal Investigator
- Principal Investigator
  
  西山和宏
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka Metropolitan University
  Kyushu University
Elucidation of the formation principle of pathologically specific protein complexes and application to amyotrophic diseasesPrincipal Investigator
- Principal Investigator
  
  Nishiyama Kazuhiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kyushu University
Atypical GPCR signaling regulated by cysteine-based post-translational modification and its physiological significancePrincipal Investigator
- Principal Investigator
  
  Nishiyama Kazuhiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kyushu University
Elucidation of molecualr mechanism underlying maintenance of living body homeostasis by mechano-activated molecules and establishment of a strategy for exercise-mimetic drug development
- Principal Investigator
  
  Motohiro Nishida
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences
  Okazaki Research Facilities, National Institutes of Natural Sciences

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

[Journal Article] The role of P2Y6 receptor in the pathogenesis of cardiovascular and inflammatory diseases2024
- Author(s)
  Nishiyama Kazuhiro
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 2 Pages: 108-112
- DOI
  10.1016/j.jphs.2024.01.003
- Data Source
  KAKENHI-PROJECT-22K06630, KAKENHI-PUBLICLY-22H04814
[Journal Article] Pharmacological Activation of TRPC6 Channel Prevents Colitis Progression2024
- Author(s)
  Nishiyama Kazuhiro、Kato Yuri、Nishimura Akiyuki、Mi Xinya、Nagata Ryu、Mori Yasuo、Azuma Yasu-Taka、Nishida Motohiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 4 Pages: 2401-2401
- DOI
  10.3390/ijms25042401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06630, KAKENHI-PROJECT-22K19395, KAKENHI-PUBLICLY-22H04814, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] L-arginine-induced pancreatitis aggravated by inhibiting Na<sup>+</sup>/Ca<sup>2+</sup> exchanger 12023
- Author(s)
  ONO Naoshige、HORIKOSHI Joji、IZAWA Takeshi、NISHIYAMA Kazuhiro、TANAKA Miyuu、KUWAMURA Mitsuru、AZUMA Yasu-Taka
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 85 Issue: 6 Pages: 657-666
- DOI
  10.1292/jvms.22-0569
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Data Source
  KAKENHI-PROJECT-22K06630
[Journal Article] Knockout of Purinergic P2Y6 Receptor Fails to Improve Liver Injury and Inflammation in Non-Alcoholic Steatohepatitis2023
- Author(s)
  Nishiyama K, Ariyoshi K, Nishimura A, Kato Y, Mi X, Kurose H, Kim SG, Nishida M.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3800-3800
- DOI
  10.3390/ijms24043800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06630, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] Interleukin-19 Gene-Deficient Mice Promote Liver Fibrosis via Enhanced TGF-β Signaling, and the Interleukin-19-CCL2 Axis Is Important in the Direction of Liver Fibrosis2023
- Author(s)
  Ono Naoshige、Fujita Takashi、Miki Mariko、Nishiyama Kazuhiro、Izawa Takeshi、Aoyama Tomoko、Kuwamura Mitsuru、Fujii Hideki、Azuma Yasu-Taka
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 7 Pages: 2064-2064
- DOI
  10.3390/biomedicines11072064
- Data Source
  KAKENHI-PROJECT-22K06630
[Journal Article] Cardiac robustness regulated by reactive sulfur species2022
- Author(s)
  Nishimura Akiyuki、Tanaka Tomohiro、Kato Yuri、Nishiyama Kazuhiro、Nishida Motohiro
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 1 Pages: 1-6
- DOI
  10.3164/jcbn.21-84
- NAID
  130008139104
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05269
[Journal Article] Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through beta-adrenoreceptors.2022
- Author(s)
  Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, Kato Y, Numaga-Tomita T, Kaneko T, Mangmool S, Kuroda T, Okubo R, Sanbo M, Hirabayashi M, Sato Y, Nakagawa Y, Kuwahara K, Nagata R, Iribe G, mori Y, Nishida M.
- Journal Title
  
  Nat Commun.
  
  Volume: 12 Issue: 1 Pages: 6374-6374
- DOI
  10.1038/s41467-022-34194-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08099, KAKENHI-PROJECT-22K12900, KAKENHI-PROJECT-22K19395, KAKENHI-PROJECT-21K15338, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-20H03673, KAKENHI-PUBLICLY-22H04814, KAKENHI-PROJECT-23K24035, KAKENHI-PROJECT-23K24078
[Journal Article] Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression2022
- Author(s)
  Nishiyama Kazuhiro、Nishimura Akiyuki、Shimoda Kakeru、Tanaka Tomohiro、Kato Yuri、Shibata Takahiro、Tanaka Hiroshi、Kurose Hitoshi、Azuma Yasu-Taka、Ihara Hideshi、Kumagai Yoshito、Akaike Takaaki、Eaton Philip、Uchida Koji、Nishida Motohiro
- Journal Title
  
  Science Signaling
  
  Volume: 15 Issue: 716 Pages: 716-716
- DOI
  10.1126/scisignal.abj0644
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K21496, KAKENHI-PROJECT-20K16008, KAKENHI-PLANNED-21H05263, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19J20086, KAKENHI-PROJECT-22K06646, KAKENHI-ORGANIZER-21H05258, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-22H00356
[Journal Article] Deletion of TRPC3 or TRPC6 Fails to Attenuate the Formation of Inflammation and Fibrosis in Non-alcoholic Steatohepatitis2021
- Author(s)
  Nishiyama Kazuhiro、Toyama Chiemi、Kato Yuri、Tanaka Tomohiro、Nishimura Akiyuki、Nagata Ryu、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 3 Pages: 431-436
- DOI
  10.1248/bpb.b20-00903
- NAID
  130007993444
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PUBLICLY-20H05512, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19K16363
[Journal Article] Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell Plasticity2020
- Author(s)
  Nishida Motohiro、Tanaka Tomohiro、Mangmool Supachoke、Nishiyama Kazuhiro、Nishimura Akiyuki
- Journal Title
  
  Journal of Lipid and Atherosclerosis
  
  Volume: 9 Issue: 1 Pages: 124-124
- DOI
  10.12997/jla.2020.9.1.124
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PUBLICLY-20H05512, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383
[Journal Article] Modulation of P2Y6R expression exacerbates pressure overload-induced cardiac remodeling in mice2020
- Author(s)
  Shimoda Kakeru、Nishimura Akiyuki、Sunggip Caroline、Ito Tomoya、Nishiyama Kazuhiro、Kato Yuri、Tanaka Tomohiro、Tozaki-Saitoh Hidetoshi、Tsuda Makoto、Nishida Motohiro
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 13926-13926
- DOI
  10.1038/s41598-020-70956-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19J20086, KAKENHI-PROJECT-19K22443
[Journal Article] TRPC3-based protein signaling complex as a therapeutic target of myocardial atrophy2020
- Author(s)
  Nishiyama K, Tanaka T, Nishimura A, Nishida M
- Journal Title
  
  Current molecular pharmacology
  
  Volume: - Issue: 2 Pages: 123-131
- DOI
  10.2174/1874467213666200407090121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K16008, KAKENHI-PROJECT-19H03383, KAKENHI-PUBLICLY-20H05512
[Journal Article] TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential‐dependent coupling with PTEN2019
- Author(s)
  Numaga‐Tomita Takuro、Shimauchi Tsukasa、Oda Sayaka、Tanaka Tomohiro、Nishiyama Kazuhiro、Nishimura Akiyuki、Birnbaumer Lutz、Mori Yasuo、Nishida Motohiro
- Journal Title
  
  The FASEB Journal
  
  Volume: 33 Issue: 9 Pages: 9785-9796
- DOI
  10.1096/fj.201802811r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K07116, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J14538, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19H03383, KAKENHI-ORGANIZER-15H05935
[Journal Article] Chronic kidney disease after 5/6 nephrectomy disturbs the intestinal microbiota and alters intestinal motility.2019
- Author(s)
  Nishiyama K, Aono K, Fujimoto Y, Kuwamura M, Okada T, Tokumoto H, et al.
- Journal Title
  
  Journal of Cellular Physiology.
  
  Volume: 234 Issue: 5 Pages: 6667-6678
- DOI
  10.1002/jcp.27408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14921
[Journal Article] Mitochondrial dynamics in exercise physiology.2019
- Author(s)
  Tanaka T, Nishimura A, Nishiyama K, Goto T, Numaga-Tomita T, Nishida M.
- Journal Title
  
  Pflugers Archiv European Journal of Physiology
  
  Volume: 印刷中 Issue: 2 Pages: 1-17
- DOI
  10.1007/s00424-019-02258-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-18H05293, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy2019
- Author(s)
  Sudi Suhaini Binti、Tanaka Tomohiro、Oda Sayaka、Nishiyama Kazuhiro、Nishimura Akiyuki、Sunggip Caroline、Mangmool Supachoke、Numaga-Tomita Takuro、Nishida Motohiro
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 9785-9785
- DOI
  10.1038/s41598-019-46252-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-19K16363, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J14538, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-19H03383
[Journal Article] Ibudilast attenuates doxorubicin‐induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes2019
- Author(s)
  Nishiyama Kazuhiro、Numaga‐Tomita Takuro、Fujimoto Yasuyuki、Tanaka Tomohiro、Toyama Chiemi、Nishimura Akiyuki、Yamashita Tomohiro、Matsunaga Naoya、Koyanagi Satoru、Azuma Yasu‐Taka、Ibuki Yuko、Uchida Koji、Ohdo Shigehiro、Nishida Motohiro
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 176 Issue: 18 Pages: 3723-3738
- DOI
  10.1111/bph.14777
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K16363, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-18K14921, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-17H06170
[Journal Article] Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload2019
- Author(s)
  Nishimura Akiyuki、Shimoda Kakeru、Tanaka Tomohiro、Toyama Takashi、Nishiyama Kazuhiro、Shinkai Yasuhiro、Numaga-Tomita Takuro、Yamazaki Daiju、Kanda Yasunari、Akaike Takaaki、Kumagai Yoshito、Nishida Motohiro
- Journal Title
  
  Science Signaling
  
  Volume: 12 Issue: 587
- DOI
  10.1126/scisignal.aaw1920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-19K16363, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19J20086, KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC channels in exercise-mimetic therapy.2018
- Author(s)
  Numaga-Tomita T, Oda S, Nishiyama K, Tanaka T, Nishimura A, Nishida M.
- Journal Title
  
  Pflugers Archiv European Journal of Physiology
  
  Volume: 471 Issue: 3 Pages: 507-517
- DOI
  10.1007/s00424-018-2211-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H05092, KAKENHI-PUBLICLY-18H04993, KAKENHI-PROJECT-19J14538, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383
[Journal Article] TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy.2018
- Author(s)
  Sunggip C, Shimoda K, Oda S, Tanaka T, Nishiyama K, Mangmool S, Nishimura A, Numaga-Tomita T and Nishida M
- Journal Title
  
  Front. Pharmacol.
  
  Volume: 9 Pages: 523-523
- DOI
  10.3389/fphar.2018.00523
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921, KAKENHI-PROJECT-16H05092, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K15464, KAKENHI-PROJECT-17K15585, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-18H05293, KAKENHI-ORGANIZER-15H05935
[Journal Article] 心臓リモデリングにおけるTRPCチャネルの役割とその治療応用2017
- Author(s)
  西田基宏、西山和宏、田中智弘
- Journal Title
  
  心臓49(12)
  
  Volume: 49 Pages: 1213-1218
- NAID
  130007580256
- Data Source
  KAKENHI-PROJECT-16H05092
[Journal Article] A protease-activated receptor-1 antagonist protects against podocyte injury in a mouse model of nephropathy2017
- Author(s)
  Guan Yu、Nakano Daisuke、Zhang Yifan、Li Lei、Liu Wenhua、Nishida Motohiro、Kuwabara Takashige、Morishita Asahiro、Hitomi Hirofumi、Mori Kiyoshi、Mukoyama Masashi、Masaki Tsutomu、Hirano Katsuya、Nishiyama Akira
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 135 Issue: 2 Pages: 81-88
- DOI
  10.1016/j.jphs.2017.09.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-16K09518, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15K09266, KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-16H05092
[Patent] COVID-19 治療薬2021
- Inventor(s)
  西田基宏、加藤百合、西山和宏、朝倉宏、諫田泰成
- Industrial Property Rights Holder
  西田基宏、加藤百合、西山和宏、朝倉宏、諫田泰成
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] Redox-dependent alternative internalization (REDAI) of purinergic P2Y6 receptor regulates colitis but not non-alcoholic steatohepatitis.2023
- Author(s)
  Nishiyama K, Nishida M.
- Organizer
  FAOPS 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] GPCRの酸化修飾及び亜鉛修飾を標的とした疾患治療に関する研究2023
- Author(s)
  西山和宏
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] 受容体作動性カチオンチャネルTRPC6を介した亜鉛流入による心機能調節機構の解明2023
- Author(s)
  西山和宏
- Organizer
  第13回トランスポーター研究会九州部会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] IL-19によるM2マクロファージを介した肝線維化進展の新規調節機構.2023
- Author(s)
  小野尚重、西山和宏、東泰孝
- Organizer
  第166回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] インターロイキン-19のL-アルギニン誘発性膵炎に対する抑制的役割の可能性．2023
- Author(s)
  小野尚重、西山和宏、東　泰孝
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] イソチオシアネート化合物による GPCR のタンパク質内在化機構の解明2023
- Author(s)
  西山和宏、西田基宏
- Organizer
  日本毒性学会付加体科学部会第1回クッキオフシンポジウム
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] Gタンパク質共役型受容体の機能修飾と生命金属に関する研究2023
- Author(s)
  西山和宏
- Organizer
  第34回日本微量元素学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] Drug discovery research targeting functional modification of G protein-coupled receptors.2023
- Author(s)
  Nishiyama K
- Organizer
  The 9th Japan-China Joint Meeting of Basic and Clinical Pharmacology.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06630
[Presentation] 受容体作動性カチオンチャネルTRPC6を介した亜鉛流入による心機能調節機構の解明2023
- Author(s)
  西山和宏
- Organizer
  第13回トランスポーター研究会九州部会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04814
[Presentation] Gタンパク質共役型受容体の機能修飾と生命金属に関する研究.2023
- Author(s)
  西山和宏
- Organizer
  第34回日本微量元素学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04814
[Presentation] 「システインSH修飾を介したGPCRの新奇タンパク質内在化機構」2021
- Author(s)
  西山和宏、西村明幸、下田　翔、田中　智弘、加藤　百合、柴田　貴広、内田　浩二、西田基宏
- Organizer
  日本薬学会薬理系部会主催「生体機能と創薬シンポジウム2021」
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] 「COVID-19重症化機構の解明及び予防・治療を目指したグリーンファルマ研究」2021
- Author(s)
  友清大樹、加藤百合、西村明幸、西山和宏、田中智弘、日下部宜宏、神谷典穂、今井由美子、朝倉宏、伊吹裕子、諫田泰成、西田基宏
- Organizer
  日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] 「TRPC3-Nox2複合体形成による筋萎縮制御」2021
- Author(s)
  加藤百合、西山和宏、田中智弘、西村明幸、西田基宏
- Organizer
  第126回日本解剖学会総会／第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] 「TRPC3-Nox2 複合体形成を標的とした COVID-19 新規治療薬の探索」2021
- Author(s)
  友清大樹、加藤百合、西山和宏、西村明幸、田中智弘、日下部宜宏、神谷典穂、今井由美子、伊吹裕子、諫田泰成、西田基宏
- Organizer
  日本酸化ストレス学会東海支部第９回学術集会
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] 「システイン修飾を介したGPCRのタンパク質品質管理機構の解明」2021
- Author(s)
  西山和宏、西村明幸、柴田貴広、内田浩二、西田基宏
- Organizer
  第74回日本酸化ストレス学会／第21回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] ミトコンドリア品質管理を標的とした炎症性腸疾患治療2020
- Author(s)
  阿部愛杜、西山和宏、田中智弘、西村明幸、加藤百合、西田基宏
- Organizer
  臨床薬理学会
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] 活性イオウによる心筋の頑健性制御2020
- Author(s)
  西村明幸、西田基宏、西山和宏、加藤百合、田中智弘
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K16008
[Presentation] Renal impairment following 5/6 nephrectomy disturbs the intestinal microbiota and alters intestinal motility2019
- Author(s)
  Kazuhiro Nishiyama, Yasu-Taka Azuma, Hidemitsu Nakajima and Tadayoshi Takeuchi
- Organizer
  第9回アジア・オセアニア生理学会連合2019年大会（The 9th Federation of the Asian and Oceanian Physiological Societies Congress）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] 多因子に着目した消化管運動機能に関わる新規調節機構の解明2019
- Author(s)
  西山和宏
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] Identification of a novel TRPC3-Nox2 complex inhibitor that attenuates anthracycline-induced cytotoxicity.2019
- Author(s)
  Nishiyama K, Tanaka T, Toyama C, Nishimura A, Nishida M.
- Organizer
  The 50th NIPS International Symposium. 'MIRACLES' in Cardiovascular Physiology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] 抗がん剤の副作用を軽減する新規TRPC3-Nox2複合体阻害薬の同定2019
- Author(s)
  西山和宏、冨田拓郎、藤本泰之、田中智弘、遠山千恵実、西村明幸、東泰孝、西田基宏
- Organizer
  第92回薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] Atypical GPCR signaling regulated by cysteine-based post-translational modification and its physiological significance.2019
- Author(s)
  Nishiyama K
- Organizer
  The 50th NIPS International Symposium. 'MIRACLES' in Cardiovascular Physiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] 抗がん剤の副作用を軽減する新規 TRPC3-Nox2 複合体阻害剤の探索および効果の検証2019
- Author(s)
  西山和宏
- Organizer
  第19回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] 新規TRPC3-Nox2複合体阻害剤の探索および効果の検証.2018
- Author(s)
  西山和宏、赤司壮一郎、冨田拓郎、藤本泰之、田中智弘、西村明幸、東泰孝、西田基宏.
- Organizer
  第71回日本薬理学会西南部
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] 抗がん剤の副作用を軽減する新規TRPC3-Nox2複合体阻害薬の探索2018
- Author(s)
  西山和宏、赤司壮一郎、冨田拓郎、藤本泰之、田中智弘、西村明幸、東泰孝、西田基宏.
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18K14921
[Presentation] Microbiota and uremic toxin contribute to intestinal motility dysregulation induced by renal impairment2018
- Author(s)
  Nishiyama K, Azuma YT, Nakajima H, Takeuchi T.
- Organizer
  The 18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14921

1. Motohiro Nishida (90342641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. Tomita Takuro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Nishimura Akiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. Shimauchi Tsukasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Oda Sayaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Tanaka Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Shimoda Kakeru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAGAWA Yasuaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 錦見俊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 桑原宏一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

nishiyama kazuhiro 西山 和宏

Nishiyama Kazuhiro 西山 和宏

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超硫黄分子センサータンパクを利用した新規超硫黄分子プローブの開発Principal Investigator

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腸内細菌叢で産生される超硫黄分子の生体における役割の解明Principal Investigator

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超硫黄を介したシグナル伝達を基軸とした腸心連関の解明Principal Investigator

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亜鉛イオンによるGPCR-Gタンパク質共役調節機構の解明Principal Investigator

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Elucidation of the formation principle of pathologically specific protein complexes and application to amyotrophic diseasesPrincipal Investigator

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Atypical GPCR signaling regulated by cysteine-based post-translational modification and its physiological significancePrincipal Investigator

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Elucidation of molecualr mechanism underlying maintenance of living body homeostasis by mechano-activated molecules and establishment of a strategy for exercise-mimetic drug development

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[Journal Article] The role of P2Y6 receptor in the pathogenesis of cardiovascular and inflammatory diseases2024

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[Journal Article] Pharmacological Activation of TRPC6 Channel Prevents Colitis Progression2024

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[Journal Article] L-arginine-induced pancreatitis aggravated by inhibiting Na<sup>+</sup>/Ca<sup>2+</sup> exchanger 12023

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[Journal Article] Knockout of Purinergic P2Y6 Receptor Fails to Improve Liver Injury and Inflammation in Non-Alcoholic Steatohepatitis2023

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[Journal Article] Interleukin-19 Gene-Deficient Mice Promote Liver Fibrosis via Enhanced TGF-β Signaling, and the Interleukin-19-CCL2 Axis Is Important in the Direction of Liver Fibrosis2023

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[Journal Article] Cardiac robustness regulated by reactive sulfur species2022

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nishiyama kazuhiro 西山和宏

Nishiyama Kazuhiro 西山和宏