Hayashi Yuichi 林祐一

Researcher Number	60811726
Other IDs	https://orcid.org/0000-0001-5279-332X
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 研究員
Affiliation (based on the past Project Information) *help	2023: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2019 – 2023: 名古屋市立大学, 医薬学総合研究院(医学), 助教 2018: 名古屋市立大学, 大学院医学研究科, 助教 2018: 名古屋市立大学, 大学院医学研究科, 臨床研究医
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 膵癌 / スクテラリン / PI3K/Aktシグナル / ゲムシタビン / Girdin / 抗癌剤耐性 / 分子標的薬剤 / NF-κB / 血管新生 / オメガ3不飽和脂肪酸 / レゾルビン … More Except Principal Investigator … More 血管新生 / 放射線耐性膵癌 / 放射線耐性 / 膵癌 / 放射線体制 / IL-Ra / IL-1RtypeⅠ / ゲムシタビン耐性膵癌 / IL-1RⅠ / IL-1α / IL-1ra / IL-1Ra / 抗癌剤耐性 / IL-1RI / CXCR4阻害剤 / 浸潤 / CXCL12/CXCR4シグナル Less

Functional Analysis of Girdin in Anticancer Drug-Resistant Pancreatic Cancer and Its Application to Novel Therapeutic AgentsPrincipal Investigator
- Principal Investigator
  
  林祐一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nagoya City University
Elucidation of chemoradiation resistance mechanisms for the development of new molecular target drugs for pancreatic cancer
- Principal Investigator
  
  Matsuo Yoichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nagoya City University
Anti-angiogenic effect of omega-3 unsaturated fatty acids in pancreatic cancer for clinical applicationPrincipal Investigator
- Principal Investigator
  
  Hayashi Yuichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nagoya City University
Examination of cancer stem cell marker CXCR4 in radiation-resistant pancreatic cancer for clinical application
- Principal Investigator
  
  Imafuji Hiroyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nagoya City University

All 2023 2022 2021 2019 2018

All Journal Article Presentation

[Journal Article] Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review2023
- Author(s)
  Denda Yuki、Matsuo Yoichi、Nonoyama Keisuke、Murase Hiromichi、Kato Tomokatsu、Hayashi Yuichi、Imafuji Hiroyuki、Saito Kenta、Morimoto Mamoru、Kato Hiroyuki、Yoshida Michihiro、Naitoh Itaru、Hayashi Kazuki、Ogawa Ryo、Takahashi Hiroki、Takiguchi Shuji
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 20 Issue: 1
- DOI
  10.3892/mco.2023.2700
- Open Access
- Data Source
  KAKENHI-PROJECT-21H03006
[Journal Article] Dual role of autotaxin as novel biomarker and therapeutic target in pancreatic neuroendocrine neoplasms2023
- Author(s)
  Toyohara Tadashi、Yoshida Michihiro
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 12 Pages: 4571-4582
- DOI
  10.1111/cas.15980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07399, KAKENHI-PROJECT-23K07444, KAKENHI-PROJECT-20K08291, KAKENHI-PROJECT-21K20844, KAKENHI-PROJECT-21H03006
[Journal Article] Upregulation of integrin-linked kinase enhances tumor progression in gemcitabine?resistant pancreatic cancer2023
- Author(s)
  Murase Hiromichi、Matsuo Yoichi、Denda Yuki、Nonoyama Keisuke、Kato Tomokatsu、Aoyama Yoshinaga、Hayashi Yuichi、Imafuji Hiroyuki、Saito Kenta、Morimoto Mamoru、Ogawa Ryo、Takahashi Hiroki、Mitsui Akira、Kimura Masahiro、Takiguchi Shuji
- Journal Title
  
  Oncology Reports
  
  Volume: 50 Issue: 3
- DOI
  10.3892/or.2023.8601
- Open Access
- Data Source
  KAKENHI-PROJECT-21H03006
[Journal Article] Girdin regulates both migration and angiogenesis in pancreatic cancer cell lines2023
- Author(s)
  Hayashi Yuichi、Matsuo Yoichi、Denda Yuki、Nonoyama Keisuke、Murase Hiromichi、Ueda Goro、Aoyama Yoshinaga、Kato Tomokatsu、Omi Kan、Imafuji Hiroyuki、Saito Kenta、Morimoto Mamoru、Ogawa Ryo、Takahashi Hiroki、Mitsui Akira、Kimura Masahiro、Takiguchi Shuji
- Journal Title
  
  Oncology Reports
  
  Volume: 50 Issue: 3
- DOI
  10.3892/or.2023.8606
- Open Access
- Data Source
  KAKENHI-PROJECT-21H03006
[Journal Article] Relevance of gene mutations and methylation to the growth of pancreatic intraductal papillary mucinous neoplasms based on pyrosequencing.2022
- Author(s)
  Asano, G., Miyabe, K., Kato, H., Yoshida, M., Sawada, T., Okamoto, Y., Sahashi, H., Atsuta, N., Kachi, K., Kato, A., Jinno, N., Natsume, M., Hori, Y., Naitoh, I., Hayashi, K., Matsuo, Y., Takahashi, S., Suzuki, H., Kataoka, H.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 419-419
- DOI
  10.1038/s41598-021-04335-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07486, KAKENHI-PROJECT-19K08449, KAKENHI-PROJECT-20K16225, KAKENHI-PROJECT-21H03006
[Journal Article] 10Z-Hymenialdisine inhibits angiogenesis by suppressing NF-κB activation in pancreatic cancer cell lines2022
- Author(s)
  Ueda Goro、Matsuo Yoichi、Murase Hiromichi、Aoyama Yoshinaga、Kato Tomokatsu、Omi Kan、Hayashi Yuichi、Imafuji Hiroyuki、Saito Kenta、Tsuboi Ken、Morimoto Mamoru、Ogawa Ryo、Takahashi Hiroki、Mitsui Akira、Kimura Masahiro、Takiguchi Shuji
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 3
- DOI
  10.3892/or.2022.8259
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03006
[Journal Article] Enhanced CXCL12/CXCR4 signaling increases tumor progression in radiation-resistant pancreatic cancer2022
- Author(s)
  Kato Tomokatsu、Matsuo Yoichi、Ueda Goro、Murase Hiromichi、Aoyama Yoshinaga、Omi Kan、Hayashi Yuichi、Imafuji Hiroyuki、Saito Kenta、Morimoto Mamoru、Ogawa Ryo、Takahashi Hiroki、Takiguchi Shuji
- Journal Title
  
  Oncology Reports
  
  Volume: 47 Issue: 4 Pages: 68-68
- DOI
  10.3892/or.2022.8279
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08808, KAKENHI-PROJECT-21H03006
[Journal Article] A hybrid approach for chronic pancreatitis: combination of laparoscopic assisted distal pancreatectomy and open Frey procedure2021
- Author(s)
  Saito Kenta、Matsuo Yoichi、Ueda Goro、Omi Kan、Hayashi Yuichi、Imafuji Hiroyuki、Tsuboi Ken、Morimoto Mamoru、Ogawa Ryo、Takahashi Hiroki、Naitoh Itaru、Hayashi Kazuki、Kataoka Hiromi、Takiguchi Shuji
- Journal Title
  
  BMC Surgery
  
  Volume: 21 Issue: 1
- DOI
  10.1186/s12893-021-01096-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03006
[Journal Article] Escin inhibits angiogenesis by suppressing interleukin?8 and vascular endothelial growth factor production by blocking nuclear factor?κB activation in pancreatic cancer cell lines2021
- Author(s)
  Omi Kan、Matsuo Yoichi、Ueda Goro、Aoyama Yoshinaga、Kato Tomokatsu、Hayashi Yuichi、Imafuji Hiroyuki、Saito Kenta、Tsuboi Ken、Morimoto Mamoru、Ogawa Ryo、Takahashi Hiroki、Takiguchi Shuji
- Journal Title
  
  Oncology Reports
  
  Volume: 45 Issue: 5 Pages: 1-9
- DOI
  10.3892/or.2021.8006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18157, KAKENHI-PROJECT-21H03006
[Presentation] 新規治療薬開発に向けた抗癌剤耐性膵癌におけるIntegrin-linked kinase（ILK）の機能解析2023
- Author(s)
  村瀬寛倫，松尾洋一，傳田悠貴，野々山敬介，加藤知克，林祐一，今藤裕之，齊藤健太，森本守，小川了，高橋広城，三井章，木村昌弘，瀧口修司
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21H03006
[Presentation] 抗癌剤耐性膵癌で発現が亢進するIntegrin-linked kinase(ILK)を標的とした新規治療薬の開発2023
- Author(s)
  村瀬寛倫，松尾洋一，傳田悠貴，野々山敬介，加藤知克，林祐一，今藤裕之，齊藤健太，森本守，小川了，高橋広城，三井章，木村昌弘，瀧口修司
- Organizer
  第27回がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-21H03006
[Presentation] 臨床応用を目的とした膵癌におけるZKSCAN3の機能解析2023
- Author(s)
  々山敬介，松尾洋一，傳田悠貴，村瀬寛倫，加藤知克，林祐一，今藤裕之，齊藤健太，森本守，小川了，高橋広城，三井章，木村昌弘，瀧口修司
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21H03006
[Presentation] 外科医療から見た膵癌に対するゲノム医療の問題点と今後の展望2023
- Author(s)
  松尾洋一，傳田悠貴，野々山敬介，村瀬寛倫，加藤知克，林祐一，今藤裕之，齊藤健太，社本智也，坪井謙，森本守，小川了，高橋広城，三井章，木村昌弘，瀧口修司
- Organizer
  第123回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21H03006
[Presentation] 癌幹細胞マーカーCXCR4に着目した膵癌における化学放射線耐性メカニズムの解明と治療応用2023
- Author(s)
  松尾洋一，杉田三郎，江口祐輝，傳田悠貴，野々山敬介，村瀬寛倫，加藤知克，林祐一，今藤裕之，齊藤健太，社本智也，坪井謙，森本守，小川了，高橋広城，瀧口修司
- Organizer
  第34回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-21H03006
[Presentation] 膵癌の放射線耐性化と癌幹細胞マーカーCXCR4の関与2019
- Author(s)
  今藤裕之, 松尾洋一, 前田杏梨, 上田悟郎, 大見関, 林祐一, 齊藤健太, 坪井謙, 森本守, 小川了, 高橋広城, 瀧口修司
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08714
[Presentation] 放射線耐性膵癌に対するCXCR4アンタゴニストの効果の検討2019
- Author(s)
  今藤裕之，松尾洋一，前田杏梨，上田悟郎，大見関，林祐一，齊藤健太，坪井謙，森本守，小川了，高橋広城，瀧口修司
- Organizer
  第52回制癌剤適応研究会
- Data Source
  KAKENHI-PROJECT-18K08714
[Presentation] Enhancement of the CXCL12/CXCR4 signaling axis with acquisition of radiation resistance in pancreatic cancer cells2019
- Author(s)
  今藤裕之, 松尾洋一, 上田悟郎, 大見関, 林祐一, 齊藤健太, 坪井謙, 森本守, 小川了, 高橋広城, 瀧口修司
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08714
[Presentation] Role of cancer stem cell marker CXCR4 in radiation resistant pancreatic cancer cells2018
- Author(s)
  今藤裕之，松尾洋一，上田悟郎，林祐一，斎藤健太，社本智也，坪井謙，森本守，高橋広城，石黒秀行，瀧口修司
- Organizer
  第30回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08714
[Presentation] Role of CXCL12/CXCR4 signaling axis in radiation resistant pancreatic cancer cells2018
- Author(s)
  今藤裕之，松尾洋一，上田悟郎，大見関，林祐一，齊藤健太，坪井謙，森本守，高橋広城，石黒秀行，瀧口修司
- Organizer
  第77回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08714
[Presentation] 放射線耐性膵癌における CXCL12/CXCR4シグナルの関与2018
- Author(s)
  今藤裕之，松尾洋一，上田悟郎，林祐一，斎藤健太，社本智也，坪井謙，森本守，坂本宣弘，高橋広城，石黒秀行，瀧口修司
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08714
[Presentation] 放射線耐性膵癌におけるCXCL12/CXCR4シグナルの役割2018
- Author(s)
  今藤裕之，松尾洋一，上田悟郎，大見関，林祐一，齊藤健太，社本智也，坪井謙，森本守，高橋広城，石黒秀行，瀧口修司
- Organizer
  第27回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08714

1. Matsuo Yoichi (40381800)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. Imafuji Hiroyuki (80790641)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
3. 坪井謙 (80592500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 高橋広城 (30381792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 上田悟郎 (00811720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. 齊藤健太 (10770240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 村瀬寛倫 (90912585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 加藤寛之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 吉田道弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 大見関

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 青山佳永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Yuichi 林 祐一

Research Projects

Research Products

Co-Researchers

Functional Analysis of Girdin in Anticancer Drug-Resistant Pancreatic Cancer and Its Application to Novel Therapeutic AgentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of chemoradiation resistance mechanisms for the development of new molecular target drugs for pancreatic cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-angiogenic effect of omega-3 unsaturated fatty acids in pancreatic cancer for clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of cancer stem cell marker CXCR4 in radiation-resistant pancreatic cancer for clinical application

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Simultaneous presentation and resection of esophageal cancer and metastasis to the pancreas: Α case report and literature review2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual role of autotaxin as novel biomarker and therapeutic target in pancreatic neuroendocrine neoplasms2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of integrin-linked kinase enhances tumor progression in gemcitabine?resistant pancreatic cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Girdin regulates both migration and angiogenesis in pancreatic cancer cell lines2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relevance of gene mutations and methylation to the growth of pancreatic intraductal papillary mucinous neoplasms based on pyrosequencing.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 10Z-Hymenialdisine inhibits angiogenesis by suppressing NF-κB activation in pancreatic cancer cell lines2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced CXCL12/CXCR4 signaling increases tumor progression in radiation-resistant pancreatic cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A hybrid approach for chronic pancreatitis: combination of laparoscopic assisted distal pancreatectomy and open Frey procedure2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Escin inhibits angiogenesis by suppressing interleukin?8 and vascular endothelial growth factor production by blocking nuclear factor?κB activation in pancreatic cancer cell lines2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 新規治療薬開発に向けた抗癌剤耐性膵癌におけるIntegrin-linked kinase（ILK）の機能解析2023

Author(s)

Organizer

Data Source

[Presentation] 抗癌剤耐性膵癌で発現が亢進するIntegrin-linked kinase(ILK)を標的とした新規治療薬の開発2023

Author(s)

Organizer

Hayashi Yuichi 林祐一