Hosokawa Motoyasu 細川元靖

Researcher Number	60812683
Other IDs
Affiliation (Current)	2025: 愛媛大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 愛媛大学, 医学系研究科, 助教 2021: 京都大学, 医学研究科, 助教 2020: 京都大学, 医学研究科, 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator 運動 / 遺伝子発現制御 / RNA結合タンパク質 / 高脂肪食 / 骨格筋代謝 / 脂質代謝 / ケミカルバイオロジー / ミトコンドリア / 筋量増加 / 運動模倣薬 … More / RNA代謝 / 運動模倣 / トランスクリプトーム比較 / 筋量制御 Less

骨格筋生物学とケミカルバイオロジーで代謝遺伝子発現機構を解明し、健康増進を目指すPrincipal Investigator
- Principal Investigator
  
  細川元靖
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Ehime University
Elucidation of Gene Expression Regulatory Networks in Skeletal Muscle Metabolism: Toward the Creation of Exercise Mimetic DrugsPrincipal Investigator
- Principal Investigator
  
  Hosokawa Motoyasu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Ehime University
  Kyoto University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation.2023
- Author(s)
  Eisho Kanemitsu, Xiangdong Zhao, Keiko Iwaisako, Asuka Inoue, Akihide Takeuchi, Shintaro Yagi, Hidetoshi Masumoto, Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Junken Aoki, Etsuro Hatano, Shinji Uemoto, Masatoshi Hagiwara
- Journal Title
  
  Translational research
  
  Volume: 255 Pages: 26-36
- DOI
  10.1016/j.trsl.2022.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17509, KAKENHI-PROJECT-19K06907, KAKENHI-PROJECT-19K22656, KAKENHI-PROJECT-23K18310, KAKENHI-PROJECT-21H05042, KAKENHI-PROJECT-23K24059
[Journal Article] Branchpoints as potential targets of exon-skipping therapies for genetic disorders2023
- Author(s)
  Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Atsuko Hagiwara, Ryo Kurosawa, Yukiya Sako, Megumu Ogawa, Masashi Ogasawara, Satoru Noguchi, Yuichi Goto, Ryosuke Takahashi, Ichizo Nishino, Masatoshi Hagiwara
- Journal Title
  
  Molecular Therapy-Nucleic Acids
  
  Volume: 33 Pages: 404-412
- DOI
  10.1016/j.omtn.2023.07.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16771, KAKENHI-PROJECT-22K20710, KAKENHI-PROJECT-22KJ2023, KAKENHI-PROJECT-20K17509
[Journal Article] Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC2023
- Author(s)
  Motoyasu Hosokawa, Ryuta Mikawa, Atsuko Hagiwara, Yukiko Okuno, Tomonari Awaya, Yuki Yamamoto, Senye Takahashi, Haruka Yamaki, Mitsujiro Osawa, Yasuhiro Setoguchi, Megumu K Saito, Shinji Abe, Toyohiro Hirai, Shimpei Gotoh, Masatoshi Hagiwara
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 10 Pages: 107731-107731
- DOI
  10.1016/j.isci.2023.107731
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K16771, KAKENHI-PROJECT-20K17509, KAKENHI-PROJECT-20H03642, KAKENHI-PROJECT-20H03687
[Journal Article] RNA-seq analysis, targeted long-read sequencing and in silico prediction to unravel pathogenic intronic events and complicated splicing abnormalities in dystrophinopathy2022
- Author(s)
  Okubo M, Noguchi S, Awaya T, Hosokawa M, Tsukui N, Ogawa M, Hayashi S, Komaki H, Mori-Yoshimura M, Oya Y, Takahashi Y, Fukuyama T, Funato M, Hosokawa Y, Kinoshita S, Matsumura T, Nakamura S, Oshiro A, Terashima H, Nagasawa T, Sato T, Shimada Y, Tokita Y, Hagiwara M, Ogata K, Nishino I
- Journal Title
  
  Human Genetics
  
  Volume: 142 Issue: 1 Pages: 59-71
- DOI
  10.1007/s00439-022-02485-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06961, KAKENHI-PROJECT-20K17509
[Journal Article] RNA制御機構の解析で明らかとなるRNA病の病態解明と新規治療法開発2021
- Author(s)
  細川元靖, 萩原正敏
- Journal Title
  
  生体の科学
  
  Volume: 72 Pages: 577-581
- Data Source
  KAKENHI-PROJECT-20K17509
[Presentation] Sfpq-KO-マウスをモデルとした骨格筋エネルギー代謝-筋量制御連関及び、SFPQ による長鎖遺伝子発現制御機構の解明2024
- Author(s)
  細川元靖、飯田慶、谷端淳、武田伸一、萩原正敏、武内章英
- Organizer
  第8回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-20K17509
[Presentation] Sfpq-KO-マウスをモデルとした骨格筋エネルギー代謝-筋量制御連関及び、SFPQ による長鎖遺伝子発現制御機構の解明2023
- Author(s)
  細川元靖、飯田慶、谷端淳、武田伸一、萩原正敏、武内章英
- Organizer
  第8回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-23K16771
[Presentation] 筋エネルギー代謝制御-筋量制御連関の解析モデルの作成2023
- Author(s)
  細川元靖、飯田慶、谷端淳、武田伸一、萩原正敏、武内章英
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K17509
[Presentation] 筋エネルギー代謝制御-筋量制御連関の解析モデルの作成2023
- Author(s)
  細川元靖、飯田慶、谷端淳、武田伸一、萩原正敏、武内章英
- Organizer
  第9回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17509
[Presentation] 筋エネルギー代謝制御-筋量制御連関の解析モデルの作成2023
- Author(s)
  細川元靖、飯田慶、谷端淳、武田伸一、萩原正敏、武内章英
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K16771
[Presentation] Deciphering the RNA-binding protein dependent crosstalk in Multi-Dimensional gene regulation2023
- Author(s)
  Takeuchi Akihide, Motoyasu Hosokawa, Masayoshi Kamon, and Koshi Imami
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-23K16771
[Presentation] RNA結合タンパク質依存性の高次遺伝子発現クロストーク制御機構の解明2023
- Author(s)
  武内章英, 細川元靖, 加門正義, 今見考志, 川上良介, 今村健志
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K16771
[Presentation] 神経細胞におけるRNA結合タンパク質複合体による高次遺伝子発現制御機構と、その破綻により発症する神経発生異常、神経変性疾患、精神疾患の解明2023
- Author(s)
  武内章英, 細川元靖, 加門正義, 今見考志, 川上良介, 今村健志
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-23K16771
[Presentation] Deciphering the RNA-binding protein dependent crosstalk in Multi-Dimensional gene regulation2023
- Author(s)
  Takeuchi Akihide, Motoyasu Hosokawa, Masayoshi Kamon, and Koshi Imami
- Organizer
  第24回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-20K17509
[Presentation] RNA結合タンパク質依存性の高次遺伝子発現クロストーク制御機構の解明2023
- Author(s)
  武内章英, 細川元靖, 加門正義, 今見考志, 川上良介, 今村健志
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K17509
[Presentation] 筋エネルギー代謝制御-筋量制御連関の解析モデルの作成2023
- Author(s)
  細川元靖、飯田慶、谷端淳、武田伸一、萩原正敏、武内章英
- Organizer
  第9回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-23K16771
[Presentation] 神経細胞におけるRNA結合タンパク質複合体による高次遺伝子発現制御機構と、その破綻により発症する神経発生異常、神経変性疾患、精神疾患の解明2023
- Author(s)
  武内章英, 細川元靖, 加門正義, 今見考志, 川上良介, 今村健志
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K17509

1. 林晋一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hosokawa Motoyasu 細川 元靖

Research Projects

Research Products

Co-Researchers

骨格筋生物学とケミカルバイオロジーで代謝遺伝子発現機構を解明し、健康増進を目指すPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Gene Expression Regulatory Networks in Skeletal Muscle Metabolism: Toward the Creation of Exercise Mimetic DrugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Branchpoints as potential targets of exon-skipping therapies for genetic disorders2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNA-seq analysis, targeted long-read sequencing and in silico prediction to unravel pathogenic intronic events and complicated splicing abnormalities in dystrophinopathy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNA制御機構の解析で明らかとなるRNA病の病態解明と新規治療法開発2021

Author(s)

Journal Title

Data Source

[Presentation] Sfpq-KO-マウスをモデルとした骨格筋エネルギー代謝-筋量制御連関及び、SFPQ による長鎖遺伝子発現制御機構の解明2024

Author(s)

Organizer

Data Source

[Presentation] Sfpq-KO-マウスをモデルとした骨格筋エネルギー代謝-筋量制御連関及び、SFPQ による長鎖遺伝子発現制御機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] 筋エネルギー代謝制御-筋量制御連関の解析モデルの作成2023

Author(s)

Organizer

Data Source

[Presentation] 筋エネルギー代謝制御-筋量制御連関の解析モデルの作成2023

Author(s)

Organizer

Data Source

[Presentation] 筋エネルギー代謝制御-筋量制御連関の解析モデルの作成2023

Author(s)

Organizer

Data Source

[Presentation] Deciphering the RNA-binding protein dependent crosstalk in Multi-Dimensional gene regulation2023

Author(s)

Organizer

Data Source

[Presentation] RNA結合タンパク質依存性の高次遺伝子発現クロストーク制御機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] 神経細胞におけるRNA結合タンパク質複合体による高次遺伝子発現制御機構と、その破綻により発症する神経発生異常、神経変性疾患、精神疾患の解明2023

Author(s)

Organizer

Data Source

[Presentation] Deciphering the RNA-binding protein dependent crosstalk in Multi-Dimensional gene regulation2023

Author(s)

Organizer

Data Source

[Presentation] RNA結合タンパク質依存性の高次遺伝子発現クロストーク制御機構の解明2023

Author(s)

Organizer

Data Source

Hosokawa Motoyasu 細川元靖