Yoshimura Saki 吉村沙紀

… Alternative Names

中川沙紀

Nakagawa Saki 中川沙紀

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Researcher Number	60814522
Affiliation (based on the past Project Information) *help	2018 – 2022: 岡山大学, 歯学部, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related
Keywords	Principal Investigator 骨粗鬆症 / テレイン / 骨免疫学 / 抗炎症 / 骨免疫 / 炎症性骨破壊 / 歯周病 / terrein / 薬剤関連性顎骨壊死 / 低分子化合物 / 骨粗鬆症治療薬 / MRONJ / 破骨細胞

Immunological analysis of the effect of small molecule compound, terrein, on the mechanism of inflammatory bone destruction.Principal Investigator
- Principal Investigator
  
  Yoshimura Saki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University
The development of novel osteoporosis drug for the super aging society -Application of low molecular compound, terrein-Principal Investigator
- Principal Investigator
  
  Nakagawa Saki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Okayama University

All 2021 2020 2019 2018 Other

All Journal Article Presentation Other

[Journal Article] The fungal metabolite (+)-terrein abrogates ovariectomy-induced bone loss and receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis by suppressing protein kinase-C α/βII phosphorylation.2021
- Author(s)
  Kyosuke Sakaida, Kazuhiro Omori, Masaaki Nakayama, Hiroki Mandai, Saki Nakagawa, Hidefumi Sako, Chiaki Kamei, Satoshi Yamamoto, Hiroya Kobayashi, Satoki Ishii, Mitsuaki Ono, Soichiro Ibaragi, Keisuke Yamashiro, Tadashi Yamamoto, Seiji Suga and Shogo Takashiba
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 674366-674366
- DOI
  10.3389/fphar.2021.674366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11668, KAKENHI-PROJECT-19K05456, KAKENHI-PROJECT-19K10108, KAKENHI-PROJECT-21K09842, KAKENHI-PROJECT-20K18509, KAKENHI-PROJECT-21K21087
[Journal Article] The Fungal Metabolite (+)-Terrein Abrogates Osteoclast Differentiation via Suppression of the RANKL Signaling Pathway through NFATc12020
- Author(s)
  S. Nakagawa, K. Omori, M. Nakayama, H. Mandai, S. Yamamoto, H. Kobayashi, H. Sako, K. Sakaida, H. Yoshimura, S. Ishii, S. Ibaragi, K. Hirai, K. Yamashiro, T. Yamamoto, S. Suga
- Journal Title
  
  Int. Immunopharmacol
  
  Volume: 83 Pages: 106429-106429
- DOI
  10.1016/j.intimp.2020.106429
- NAID
  120006892916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05478, KAKENHI-PUBLICLY-18H04415, KAKENHI-PROJECT-18K17069, KAKENHI-PROJECT-17K11668, KAKENHI-PROJECT-19K05456, KAKENHI-PROJECT-19K10108, KAKENHI-PROJECT-20K18509
[Journal Article] Fungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts2018
- Author(s)
  Satoshi Yamamoto, Kazuhiro Omori, Hiroki Mandai, Masaaki Nakayama, Saki Nakagawa, Hiroya Kobayashi, Tadashi Kunimine, Hiroshi Yoshimura, Kyosuke Sakaida, Hidefumi Sako, Soichiro Ibaragi, Tadashi Yamamoto, Hiroshi Maeda, Seiji Suga, and Shogo Takashiba
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 11 Pages: e00979-e00979
- DOI
  10.1016/j.heliyon.2018.e00979
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11668, KAKENHI-PROJECT-18K17069, KAKENHI-PROJECT-16K11549, KAKENHI-PROJECT-17K17903
[Presentation] 真菌代謝産物(+)-terreinがマウス骨粗鬆症モデルにおける骨代謝に及ぼす影響2020
- Author(s)
  坂井田京佑, 大森一弘, 中川沙紀, 佐光秀文, 亀井千晶, 山本総司, 小林寛也, 山城圭介, 山本直史, 高柴正悟
- Organizer
  日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-20K18509
[Presentation] 真菌二次代謝産物(+)-terreinはTNF-αの発現を抑制し歯周炎マウスモデルにおける歯槽骨吸収を抑制する2020
- Author(s)
  佐光秀文, 大森一弘, 中川沙紀, 亀井千晶, 坂井田京佑, 山本総司, 井手口英隆, 小林寛也, 山城圭介, 山本直史, 高柴正悟
- Organizer
  日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K18509
[Presentation] 真菌二次代謝産物terreinはマウス歯周病モデルにおける歯槽骨吸収を抑制する2019
- Author(s)
  佐光秀文, 大森一弘, 中川沙紀, 坂井田京佑, 山本総司, 青柳浩明, 小林寛也, 大野充昭, 平井公人, 山城圭介, 山本直史, 高柴正悟
- Organizer
  第39回日本歯科薬物療法学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-18K17069
[Presentation] 真菌二次代謝産物terreinはマウス骨粗鬆症モデルにおいて大腿骨吸収を抑制する2019
- Author(s)
  坂井田京佑, 大森一弘, 中川沙紀, 佐光秀文, 山本総司, 小林寛也, 平井公人, 山城圭介, 山本直史, 高柴正悟
- Organizer
  日本歯周病学会
- Data Source
  KAKENHI-PROJECT-18K17069
[Presentation] 真菌二次代謝産物(+)-terreinはマウス実験的歯周炎モデルにおける歯槽骨吸収を抑制する2018
- Author(s)
  佐光秀文, 大森一弘, 中川沙紀, 坂井田京佑, 山本総司, 青柳浩明, 小林寛也, 山城圭介, 山本直史, 高柴正悟
- Organizer
  第149回日本歯科保存学会秋季学術大会
- Data Source
  KAKENHI-PROJECT-18K17069
[Presentation] 真菌二次代謝産物(+)-terreinはヒト歯肉上皮細胞におけるAggregatibacter actinomycetemcomitans刺激による細胞間接着分子の発現低下を抑制する2018
- Author(s)
  中村亜里紗, 大森一弘, 小林寛也, 冨川知子, 山本総司, 中川沙紀, 山本直史, 高柴正悟
- Organizer
  第148回日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-18K17069
[]

1. OMORI Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. NAKAYAMA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 菅誠治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshimura Saki 吉村 沙紀

中川沙紀

Nakagawa Saki 中川 沙紀

Research Projects

Research Products

Co-Researchers

Immunological analysis of the effect of small molecule compound, terrein, on the mechanism of inflammatory bone destruction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of novel osteoporosis drug for the super aging society -Application of low molecular compound, terrein-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The fungal metabolite (+)-terrein abrogates ovariectomy-induced bone loss and receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis by suppressing protein kinase-C α/βII phosphorylation.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Fungal Metabolite (+)-Terrein Abrogates Osteoclast Differentiation via Suppression of the RANKL Signaling Pathway through NFATc12020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Fungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 真菌代謝産物(+)-terreinがマウス骨粗鬆症モデルにおける骨代謝に及ぼす影響2020

Author(s)

Organizer

Data Source

[Presentation] 真菌二次代謝産物(+)-terreinはTNF-αの発現を抑制し歯周炎マウスモデルにおける歯槽骨吸収を抑制する2020

Author(s)

Organizer

Data Source

[Presentation] 真菌二次代謝産物terreinはマウス歯周病モデルにおける歯槽骨吸収を抑制する2019

Author(s)

Organizer

Data Source

[Presentation] 真菌二次代謝産物terreinはマウス骨粗鬆症モデルにおいて大腿骨吸収を抑制する2019

Author(s)

Organizer

Data Source

[Presentation] 真菌二次代謝産物(+)-terreinはマウス実験的歯周炎モデルにおける歯槽骨吸収を抑制する2018

Author(s)

Organizer

Data Source

[Presentation] 真菌二次代謝産物(+)-terreinはヒト歯肉上皮細胞におけるAggregatibacter actinomycetemcomitans刺激による細胞間接着分子の発現低下 を抑制する2018

Author(s)

Organizer

Data Source

[]

Yoshimura Saki 吉村沙紀

Nakagawa Saki 中川沙紀

[Presentation] 真菌二次代謝産物(+)-terreinはヒト歯肉上皮細胞におけるAggregatibacter actinomycetemcomitans刺激による細胞間接着分子の発現低下を抑制する2018