Maehara Touko 前原都有子

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Maehara Toko 前原都有子

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Researcher Number	60825529
Other IDs	https://orcid.org/0000-0001-7579-8553
Affiliation (Current)	2024: 岩手大学, 農学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2022: 岩手大学, 農学部, 助教 2021 – 2022: 大阪医科薬科大学, 薬学部, 助教 2018 – 2020: 大阪薬科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / 0801:Pharmaceutical sciences and related fields Except Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator プロスタグランジン / 敗血症 / 肺機能 / 肺炎 Except Principal Investigator 脂質 / エイコサノイド / 肥満

プロスタグランジンによる敗血症の病態制御機構の解明および診断・治療への応用Principal Investigator
- Principal Investigator
  
  前原都有子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Iwate University
Regulation mechanism of obesity by eicosanoids
- Principal Investigator
  
  Fujimori Ko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University of Pharmaceutical Sciences
investigation of the role of prostaglandin in lung inflammationPrincipal Investigator
- Principal Investigator
  
  Maehara Toko
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0801:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Leukotriene C4 synthase is a novel PPARγ target gene, and leukotriene C4 and D4 activate adipogenesis through cysteinyl LT1 receptors in adipocytes2022
- Author(s)
  Ko Fujimori, Saki Uno, Kyohei Kuroda, Chihiro Matsumoto, Toko Maehara
- Journal Title
  
  Biochim Biophys Acta Mol. Cell Res.
  
  Volume: 1869 Issue: 3 Pages: 119203-119203
- DOI
  10.1016/j.bbamcr.2021.119203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07024, KAKENHI-PROJECT-21K15279
[Journal Article] Inhibition of Prostaglandin F 2α Receptors Exaggerates HCl-Induced Lung Inflammation in Mice2021
- Author(s)
  Fujimori, K., Maehara, T.
- Journal Title
  
  Int J Mol Sci .
  
  Volume: 22 Issue: 23 Pages: 12843-12843
- DOI
  10.3390/ijms222312843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15279
[Journal Article] Contribution of FP receptors in M1 macrophage polarization via IL-10-regulated nuclear translocation of NF-κB p65.2020
- Author(s)
  Maehara, Toko, Fujimori, Ko
- Journal Title
  
  Biochim. Biophys. Acta Mol. Cell. Biol. Lipids.
  
  Volume: 1865 Issue: 5 Pages: 158654-158654
- DOI
  10.1016/j.bbalip.2020.158654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21235
[Journal Article] Limonoid 7-deacetoxy-7-oxogedunin from andiroba, Carapa guianensis, Meliaceae, decreased body weight gain, improved insulin sensitivity, and activated brown adipose tissue in high-fat-diet-fed mice.2020
- Author(s)
  Matsumoto, Chihiro, Maehara, Toko, Tanaka, Reiko, Fujimori, Ko
- Journal Title
  
  J. Agric. Food Chem.
  
  Volume: 67 Issue: 36 Pages: 10107-10115
- DOI
  10.1021/acs.jafc.9b04362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21235
[Journal Article] Hematopoietic prostaglandin D synthase-derived prostaglandin D2 ameliorates adjuvant-induced joint inflammation in mice.2019
- Author(s)
  Yoshiki Tsubosaka, Toko Maehara, Daiki Imai, Tatsuro Nakamura, Koji Kobayashi, Nanae Nagata, Wataru Fujii, Takahisa Murata
- Journal Title
  
  FASEB Journal
  
  Volume: 印刷中 Issue: 6 Pages: 6829-6837
- DOI
  10.1096/fj.201802153r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21235, KAKENHI-PROJECT-17H01509, KAKENHI-PROJECT-17H06252
[Journal Article] L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance.2019
- Author(s)
  Fujimori K, Aritake K, Oishi Y, Nagata N, Maehara T, Lazarus M, Urade Y.
- Journal Title
  
  Sci. Rep
  
  Volume: 9 Issue: 1 Pages: 1931-1931
- DOI
  10.1038/s41598-018-38453-y
- NAID
  120007128200
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01881, KAKENHI-PROJECT-19K21235, KAKENHI-PROJECT-16K08256, KAKENHI-PROJECT-18H02534
[Journal Article] Epithelial cell?derived prostaglandin D2 inhibits chronic allergic lung inflammation in mice2019
- Author(s)
  Maehara Toko、Nakamura Tatsuro、Maeda Shingo、Aritake Kosuke、Nakamura Masataka、Murata Takahisa
- Journal Title
  
  The FASEB Journal
  
  Volume: 印刷中 Issue: 7 Pages: 8202-8210
- DOI
  10.1096/fj.201802817r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21235, KAKENHI-PROJECT-17H01509, KAKENHI-PROJECT-17H06252
[Presentation] プロスタグランジンF2αがマウスの喘息および認知機能に及ぼす影響について2023
- Author(s)
  冨士村純輝，亀水麻衣，草山実久，小林加奈，前原都有子，佐藤洋
- Organizer
  第5回日本獣医薬理学・毒性学会春季研究会
- Data Source
  KAKENHI-PROJECT-21K15279
[Presentation] 慢性腎臓病モデルラットにおける認知機能，抑うつ・不安様行動の評価および脳由来神経栄養因子 (BDNF) の変化2022
- Author(s)
  井上聡士、中谷仁美、鈴木かんな、山口拓人、富士村純輝、大野晃治、前原都有子、佐藤洋
- Organizer
  日本獣医学会第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15279
[Presentation] 慢性腎臓病（ CKD）モデルラットにおける認知機能障害，不安・抑うつ様行動の評価および海馬での脳由来神経栄養因子（ BDNF）発現の変化2022
- Author(s)
  山口拓人、井上聡士、鈴木かんな、冨士村純輝、大野晃治、前原都有子、佐藤洋
- Organizer
  日本獣医学会第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15279
[Presentation] ビンクリスチン誘発筋障害の病理発生に関する解析2022
- Author(s)
  鈴木かんな、髙井雄也、井上聡士、山口拓人、冨士村純輝、大野晃治、前原都有子、佐藤洋
- Organizer
  日本獣医学会第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15279
[Presentation] ジェンツーペンギンの全身麻酔における麻酔前投与薬の効果2022
- Author(s)
  大野晃治、前原都有子、佐藤
- Organizer
  日本獣医学会第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15279
[Presentation] プロスタグランジン F2αは肺炎の悪化を抑制する2021
- Author(s)
  前原都有子, 藤森功
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K15279
[Presentation] 肺炎におけるプロスタグランジンF2α の機能解析2021
- Author(s)
  前原都有子, 藤森功
- Organizer
  第71回日本薬学会関西支部会
- Data Source
  KAKENHI-PROJECT-21K15279
[Presentation] 脂肪細胞が産生するロイコトリエンC4の産生制御と機能解析2021
- Author(s)
  宇野早紀、黒田恭平、前原都有子、藤森功
- Organizer
  第70回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-20K07024
[Presentation] The role of PGF2α in the progression of LPS-induced sepsis2019
- Author(s)
  Toko Maehara, Ko Fujimori
- Organizer
  60th International Conference on the Bioscience of Lipids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] プロスタグランジンF2αによる敗血症制御機構の解明2019
- Author(s)
  前原都有子、東垂水郁圭、近藤理沙、藤森功
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] プロスタグランジンF2αは肺炎の悪化を制御する2019
- Author(s)
  前原都有子、藤森功
- Organizer
  第66回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] PGF2α regulates the progression of LPS-induced sepsis2019
- Author(s)
  Toko Maehara, Fumiyoshi Higashitarumi, Risa Kondo, Ko Fujimori
- Organizer
  16th International Conference Bioactive Lipids in Cancer, Inflammation and Related Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] プロスタグランジンF2αは敗血症の悪化を抑制する2019
- Author(s)
  前原都有子、東垂水郁圭、近藤理沙、藤森功
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] PGF2α exaggerates LPS-induced sepsis in mice2019
- Author(s)
  Toko Maehara, Fumiyoshi Higashitarumi, Risa Kondo, Ko Fujimori
- Organizer
  2019ASCB/EMBO Meeting Cell Biology for the 21st Century
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] H-PGDS由来のPGD2は気道のムチン合成と放出を制御する2019
- Author(s)
  前原都有子　村達郎　藤森功　村田幸久
- Organizer
  第1回　日本比較薬理学毒性学会
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] 敗血症におけるプロスタグランジンF2αの機能解明2019
- Author(s)
  前原都有子、藤森功
- Organizer
  第61回日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] 肥満細胞由来のPGD2は気道のムチン合成と放出を制御する2018
- Author(s)
  前原都有子　中村達郎　藤森功　村田幸久
- Organizer
  第60回　日本脂質生化学会
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] 急性肺炎におけるプロスタグランジンF2αの機能解析2018
- Author(s)
  前原都有子　藤森功
- Organizer
  第68回　日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] PGF2αは肺炎の悪化を抑制する2018
- Author(s)
  前原都有子　藤森功
- Organizer
  第17回　次世代を担う若手ファーマ・バイオフォーラム
- Data Source
  KAKENHI-PROJECT-19K21235
[Presentation] マクロファージの極性変化におけるプロスタグランジンの影響2018
- Author(s)
  前原都有子　藤森功
- Organizer
  第91回　日本生化学大会
- Data Source
  KAKENHI-PROJECT-19K21235

1. Fujimori Ko (70425453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 小池敦資 (00625725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 裏出良博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maehara Touko 前原 都有子

Maehara Toko 前原 都有子

Research Projects

Research Products

Co-Researchers

プロスタグランジンによる敗血症の病態制御機構の解明および診断・治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation mechanism of obesity by eicosanoids

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

investigation of the role of prostaglandin in lung inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Leukotriene C4 synthase is a novel PPARγ target gene, and leukotriene C4 and D4 activate adipogenesis through cysteinyl LT1 receptors in adipocytes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of Prostaglandin F 2α Receptors Exaggerates HCl-Induced Lung Inflammation in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Contribution of FP receptors in M1 macrophage polarization via IL-10-regulated nuclear translocation of NF-κB p65.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Limonoid 7-deacetoxy-7-oxogedunin from andiroba, Carapa guianensis, Meliaceae, decreased body weight gain, improved insulin sensitivity, and activated brown adipose tissue in high-fat-diet-fed mice.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hematopoietic prostaglandin D synthase-derived prostaglandin D2 ameliorates adjuvant-induced joint inflammation in mice.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] L-PGDS-produced PGD2 in premature, but not in mature, adipocytes increases obesity and insulin resistance.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Epithelial cell?derived prostaglandin D2 inhibits chronic allergic lung inflammation in mice2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] プロスタグランジンF2αがマウスの喘息および認知機能に及ぼす影響について2023

Author(s)

Organizer

Data Source

[Presentation] 慢性腎臓病モデルラットにおける認知機能，抑うつ・不安様行動の評価お よび脳由来神経栄養因子 (BDNF) の変化2022

Author(s)

Organizer

Data Source

[Presentation] 慢性腎臓病（ CKD）モデルラットにおける認知機能障害，不安・抑うつ様 行動の評価および海馬での脳由来神経栄養因子（ BDNF）発現の変化2022

Author(s)

Organizer

Data Source

[Presentation] ビンクリスチン誘発筋障害の病理発生に関する解析2022

Author(s)

Organizer

Data Source

[Presentation] ジェンツーペンギンの全身麻酔における麻酔前投与薬の効果2022

Author(s)

Organizer

Data Source

[Presentation] プロスタグランジン F2αは肺炎の悪化を抑制する2021

Maehara Touko 前原都有子

Maehara Toko 前原都有子

[Presentation] 慢性腎臓病モデルラットにおける認知機能，抑うつ・不安様行動の評価および脳由来神経栄養因子 (BDNF) の変化2022

[Presentation] 慢性腎臓病（ CKD）モデルラットにおける認知機能障害，不安・抑うつ様行動の評価および海馬での脳由来神経栄養因子（ BDNF）発現の変化2022