Nasu Yusuke 那須雄介

Researcher Number	60831328
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院理学系研究科(理学部), 客員共同研究員
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京大学, 大学院理学系研究科(理学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 37010:Bio-related chemistry / Transformative Research Areas, Section (III) Except Principal Investigator Basic Section 47040:Pharmacology-related / Medium-sized Section 10:Psychology and related fields
Keywords	Principal Investigator 乳酸 / Metabolism / 蛍光バイオセンサー / 蛍光タンパク質 / 蛍光センサー / タンパク質工学 Except Principal Investigator 乳酸代謝 / 乳酸 / 2光子顕微鏡 / 大脳皮質視覚野 … More / 神経可塑性 / アストロサイト / ニューロン / 体温制御 / 疲労 / 低体温・低代謝 / TRAP / 疲労困憊運動 Less

Development of ultrahigh-performance quantitative L-lactate biosensorPrincipal Investigator
- Principal Investigator
  
  那須雄介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  The University of Tokyo
Optogenetic control of L-lactate for elucidating the interaction between neurons and glial cellsPrincipal Investigator
- Principal Investigator
  
  那須雄介
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
Capturing the neuronal circuit that induces fatigue-like state
- Principal Investigator
  
  征矢晋吾
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 10:Psychology and related fields
- Research Institution
  University of Tsukuba
大脳皮質視覚野臨界期の神経可塑性における乳酸代謝の寄与の解明
- Principal Investigator
  
  神戸悠輝
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kagoshima University
A third generation of genetically encoded fluorescent lactate biosensorPrincipal Investigator
- Principal Investigator
  
  Nasu Yusuke
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  The University of Tokyo
Development of Ultrasensitive Fluorescent Lactate Indicator for Intercellular MetabolismPrincipal Investigator
- Principal Investigator
  
  Nasu Yusuke
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019

All Journal Article Presentation Book

[Book] 月刊細胞2023
- Author(s)
  那須雄介
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-21K14738
[Book] 先端の分析法新訂第２版2022
- Author(s)
  那須　雄介
- Total Pages
  8
- Publisher
  NTS
- ISBN
  9784860437374
- Data Source
  KAKENHI-PROJECT-21K14738
[Book] 化学2022
- Author(s)
  那須　雄介
- Total Pages
  2
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-21K14738
[Journal Article] The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria2023
- Author(s)
  Bassot Arthur、Chen Junsheng、Takahashi-Yamashiro Kei、他17名
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 1 Pages: 111899-111899
- DOI
  10.1016/j.celrep.2022.111899
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05633, KAKENHI-PROJECT-21K14738, KAKENHI-PUBLICLY-22H04743
[Journal Article] Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging2023
- Author(s)
  Nasu Yusuke、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 6598-6598
- DOI
  10.1038/s41467-023-42230-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17927, KAKENHI-PROJECT-22K14779, KAKENHI-PROJECT-23K06151, KAKENHI-PUBLICLY-22H04743, KAKENHI-PROJECT-22H00411
[Journal Article] High performance genetically-encoded green fluorescent biosensors for intracellular L-lactate2022
- Author(s)
  Le G. N. T., Hario S., Takahashi-Yamashiro K., Li S., Drobizhev M., Nasu Y.*, Campbell R. E.*
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.10.19.512892
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14738
[Journal Article] A genetically encoded far‐red fluorescent calcium ion biosensor derived from a biliverdin‐binding protein2022
- Author(s)
  Hashizume Rina、Fujii Hajime、Mehta Sohum、Ota Keisuke、Qian Yong、Zhu Wenchao、Drobizhev Mikhail、Nasu Yusuke、Zhang Jin、Bito Haruhiko、Campbell Robert E.
- Journal Title
  
  Protein Science
  
  Volume: 31 Issue: 10
- DOI
  10.1002/pro.4440
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05633, KAKENHI-PROJECT-21K14738, KAKENHI-PUBLICLY-22H04743, KAKENHI-ORGANIZER-19H05794
[Journal Article] A red fluorescent genetically encoded biosensor for extracellular L-lactate2022
- Author(s)
  Nasu Yusuke、Kamijo Yuki、Hashizume Rina、Sato Haruaki、Hori Yukiko、Tomita Taisuke、Drobizhev Mikhail、Campbell Robert E.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.08.30.505811
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-22KJ0968, KAKENHI-PROJECT-21K14738
[Journal Article] Improved genetically encoded fluorescent biosensors for monitoring of intra- and extracellular L-lactate2022
- Author(s)
  Nasu Y.*, Aggarwal A., Le G. N. T., Kamijo Y., Boisvert M., Paquet M-E., Drobizhev M., Podgorski K., Campbell R. E.*
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.12.27.522013
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14738
[Journal Article] Chemigenetic indicators based on synthetic chelators and green fluorescent protein2022
- Author(s)
  Zhu Wenchao、Takeuchi Shiori、Imai Shosei、Terada Tohru、Ueda Takumi、Nasu Yusuke、Terai Takuya、Campbell Robert E.
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 19 Issue: 1 Pages: 38-44
- DOI
  10.1038/s41589-022-01134-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05633, KAKENHI-PROJECT-21K14738, KAKENHI-PUBLICLY-21H00273, KAKENHI-PUBLICLY-22H04743
[Journal Article] Structure- and mechanism-guided design of single fluorescent protein-based biosensors2021
- Author(s)
  Nasu Y., Shen Y., Kramer L., Campbell R.E.
- Journal Title
  
  Nature Chemical Biology
  
  Volume: N/A Issue: 5 Pages: 509-518
- DOI
  10.1038/s41589-020-00718-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15691, KAKENHI-PROJECT-19H05633
[Journal Article] A genetically encoded fluorescent biosensor for extracellular L-lactate2021
- Author(s)
  Yusuke Nasu, Ciaran Murphy-Royal, Yurong Wen, Jordan N. Haidey, Rosana S. Molina, Abhi Aggarwal, Shuce Zhang, Yuki Kamijo, Marie-Eve Paquet, Kaspar Podgorski, Mikhail Drobizhev, Jaideep S. Bains, M. Joanne Lemieux, Grant R. Gordon & Robert E. Campbell
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 7058-7058
- DOI
  10.1038/s41467-021-27332-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14738, KAKENHI-PROJECT-19H05633
[Journal Article] A genetically encoded fluorescent biosensor for extracellular L-lactate2021
- Author(s)
  Y. Nasu, C. Murphy-Royal, Y. Wen, J. Haidey, M.R.S. Molina, A. Aggarwal, S. Zhang, Y. Kamijo, M.-E. Paquet, K. Podgorski, M. Drobizhev, J.S. Bains, M.J. Lemieux, G.R. Gordon, R.E. Campbell
- Journal Title
  
  bioRxiv
  
  Volume: N/A
- DOI
  10.1101/2021.03.05.434048
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15691
[Journal Article] Engineering genetically encoded fluorescent indicators for imaging of neuronal activity: Progress and prospects2020
- Author(s)
  Shen Yi、Nasu Yusuke、Shkolnikov Irene、Kim Anna、Campbell Robert E.
- Journal Title
  
  Neuroscience Research
  
  Volume: 152 Pages: 3-14
- DOI
  10.1016/j.neures.2020.01.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05633, KAKENHI-PROJECT-19K15691
[Presentation] 高感度蛍光乳酸バイオセンサー -LACCOシリーズ-2023
- Author(s)
  Nasu Y., Kamijo Y., Le G., Hario S., and Robert E. Campbell
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] High-performance genetically encoded biosensors for L-lactate2022
- Author(s)
  Nasu Y., Le G., Hario S., Kamijo Y., and Robert E. Campbell
- Organizer
  The 45th Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] Genetically encoded fluorescent biosensors for neuroscience2022
- Author(s)
  Nasu Y.
- Organizer
  Multiphoton Workshop 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] LACCO series: Genetically encoded fluorescent biosensors for extracellular and intracellular L-lactate2022
- Author(s)
  Nasu Y., Kamijo Y., Hario S., Le G. N. T., and Campbell R. E.
- Organizer
  Society for Neuroscience 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] 乳酸バイオセンサーの開発2022
- Author(s)
  那須雄介, 針尾紗彩, Robert E. Campbell
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] Lactate matters: Genetically encoded lactate biosensors2022
- Author(s)
  Nasu Y.
- Organizer
  Serendipity Workshop 2022
- Invited
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] 乳酸バイオセンサーの開発2022
- Author(s)
  Nasu Y., Le G., Hario S., Kamijo Y., and Robert E. Campbell
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] Engineering of genetically encoded fluorescent sensors2021
- Author(s)
  Nasu Y., and Robert E. Campbell
- Organizer
  Pacifichem
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] An ultrasensitive fluorescent biosensor for L-lactate2021
- Author(s)
  Nasu Y., and Robert E. Campbell
- Organizer
  Pacifichem
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14738
[Presentation] An ultrasensitive fluorescent biosensor for L-lactate2021
- Author(s)
  Nasu Y. and Campbell R.E.
- Organizer
  Pacifichem
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15691
[Presentation] Development of Genetically Encoded Fluorescent Indicator2020
- Author(s)
  Nasu Y., and Robert E. Campbell
- Organizer
  The 4th ETH Zurich UTokyo Strategic Partnership Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15691
[Presentation] Development of a genetically encoded intensiometric lactate indicator iLACCO12019
- Author(s)
  Nasu Y., and Robert E. Campbell
- Organizer
  ACS Fall 2019 National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15691

1. 草木迫司 (80815316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 新井敏 (70454056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 征矢晋吾 (90791442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松井崇 (80725549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 神戸悠輝 (60549913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 玉川直 (20611065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐藤達雄 (90830993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. キャンベルロバート.アール

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 富田泰輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 堀由起子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nasu Yusuke 那須 雄介

Research Projects

Research Products

Co-Researchers

Development of ultrahigh-performance quantitative L-lactate biosensorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optogenetic control of L-lactate for elucidating the interaction between neurons and glial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Capturing the neuronal circuit that induces fatigue-like state

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大脳皮質視覚野臨界期の神経可塑性における乳酸代謝の寄与の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A third generation of genetically encoded fluorescent lactate biosensorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Ultrasensitive Fluorescent Lactate Indicator for Intercellular MetabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 月刊細胞2023

Author(s)

Total Pages

Publisher

Data Source

[Book] 先端の分析法 新訂第２版2022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 化学2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High performance genetically-encoded green fluorescent biosensors for intracellular L-lactate2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A genetically encoded far‐red fluorescent calcium ion biosensor derived from a biliverdin‐binding protein2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A red fluorescent genetically encoded biosensor for extracellular L-lactate2022

Author(s)

Journal Title

DOI

Nasu Yusuke 那須雄介

[Book] 先端の分析法新訂第２版2022